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Article: [Preface].

He, J

Zhonghua zhong liu za zhi [Chinese journal of oncology

2022 Volume 44, Issue 7, Page(s) 593

Language	Chinese
Publishing date	2022-07-26
Publishing country	China
Document type	Journal Article
ZDB-ID	603424-x
ISSN	0253-3766
ISSN	0253-3766
DOI	10.3760/cma.j.issn.0253-3766.2022.07.101
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Article ; Online: Construction and simulation of a joint scale model for power electronic converters based on wavelet decomposition and reconstruction algorithms.

He, Jianhua

PloS one

2024 Volume 19, Issue 4, Page(s) e0298590

Abstract: In power electronics systems, system design and operation often involve multiple time and space scales, ranging from nanosecond switching dynamics to hour-level system operation behavior. Due to the complexity of these systems and the rise of wide-gap ... ...

Abstract	In power electronics systems, system design and operation often involve multiple time and space scales, ranging from nanosecond switching dynamics to hour-level system operation behavior. Due to the complexity of these systems and the rise of wide-gap semiconductor technology, a series of multi-scale phenomena have emerged that are difficult to ignore. The high frequency of switching operations makes multi-scale effects particularly significant, including the fast dynamic response of the power loop, EMI, and heat conduction problems. They are key factors that must be considered in the design to ensure the efficient and reliable operation of power electronic devices. This study proposes the construction and simulation of a joint scale model for power electronic converters based on wavelet decomposition and reconstruction algorithms to address the multi-scale phenomenon and limitations of single-scale power electronic converters. Firstly, a joint scale model for power electronic converters at both macro and micro-scales was established, targeting both single-scale models and simple combinations of multiple scale models for power electronic converters. The traditional single-scale model is sufficient to describe the average behavior of the converter, but it has serious limitations in capturing fast transient processes and high-frequency switching behavior in power electronic systems. These limitations often manifest themselves when there is a need to capture fine timescales of detail. By transforming between the time domain and the frequency domain, wavelet decomposition enables the model to capture both macroscopic average characteristics and microscopic transient dynamics. The wavelet reconstruction algorithm can simulate all kinds of fast changes in the actual working process more accurately and compress irrelevant information while retaining key signal features, so as to optimize the simulation performance of the model. Secondly, this algorithm is used to analyze BC in short time scale. Finally, the short time scale characteristics of power electronic converters are analyzed. Experimental results show that the fusion of wavelet decomposition and reconstruction algorithm enhances the accuracy of the power electronic converter model and improves the performance of the system. The model achieves an error reduction of nearly 3% in the calculation step size of 10-7s, which has a significant impact on the high precision requirements of high-frequency operations. In addition, the optimal calculation step size of 8×10-8s achieves an error reduction of more than 14%, making an important contribution to the transient analysis and fine structure simulation. The wavelet algorithm can improve the accuracy of multi-scale modeling in power electronic system and reduce the simulation time. The reduction of error not only shows the improvement of the accuracy of the model, but also shows its practical significance in the design and test of the actual power electronic system. The reduction in error reveals the ability to more accurately predict and mitigate potential performance problems in matching tests with actual hardware, as well as its ability to adapt to emerging wide bandgap semiconductor materials and structures.
MeSH term(s)	Algorithms ; Computer Simulation ; Electronics ; Heart Rate
Language	English
Publishing date	2024-04-05
Publishing country	United States
Document type	Journal Article
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0298590
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Book ; Thesis: Anteilige Haftung für ärztliche Behandlungsfehler

He, Jian

(Schriften zum Gesundheitsrecht ; 43)

2017

Abstract: Die Arbeit befasst sich mit dem oft unaufklärbaren und als Black Box bezeichneten Kausalitätsproblem bei der Haftung für ärztliche Behandlungsfehler. Es gibt dafür grundsätzlich zwei Lösungsansätze, nämlich das Alles-oder-nichts-Prinzip und die anteilige ...

Series title	Schriften zum Gesundheitsrecht ; 43
Abstract	Die Arbeit befasst sich mit dem oft unaufklärbaren und als Black Box bezeichneten Kausalitätsproblem bei der Haftung für ärztliche Behandlungsfehler. Es gibt dafür grundsätzlich zwei Lösungsansätze, nämlich das Alles-oder-nichts-Prinzip und die anteilige Haftung. Ersteres findet sich zwar in Form der Beweislastumkehr bei grobem Behandlungsfehler im geltenden Recht, es gibt dafür aber keine überzeugende dogmatische Begründung. Letztere hingegen ist an sich logisch schlüssig und konsequent, zum...
Keywords	LLWOG30 ; LLWBB80 ; MHMA090 ; LLWU045 ; LLWA060 ; Behandlungsfehler ; Proportionalhaftung ; Verlorene Chance
Language	German
Size	187 p.
Edition	1
Publisher	Duncker & Humblot GmbH
Document type	Book ; Thesis
Note	Hochschulschriften Medizin
Format	157 x 233
ISBN	9783428150014 ; 3428150015
Database	PDA

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Article: [Research on Yaowang Temple based on local chronicles of Henan].

He, J Y / He, J / Zhang, S S

Zhonghua yi shi za zhi (Beijing, China : 1980)

2024 Volume 54, Issue 1, Page(s) 58–61

Abstract: By looking up the local chronicles of the China Digital Chronicles Database and the China Chronicles Database, it was found that there are 450 kinds of local chronicles in Henan, of which 45 contain Yaowang Temple.According to these 45 kinds of local ... ...

Abstract	By looking up the local chronicles of the China Digital Chronicles Database and the China Chronicles Database, it was found that there are 450 kinds of local chronicles in Henan, of which 45 contain Yaowang Temple.According to these 45 kinds of local Chronicles, it can be seen that a total of 35 Yaowang temples were built in 25 counties (cities) of Henan, mostly distributed in the west, north and south of Henan, especially in the west. Among them, eight Yaowang temples recorded the construction time, from the Ming Dynasty to the Republic of China, but most of them were built in the Qing Dynasty. There are records of the builders of the 8 Yaowang Temples, most of whom were local government officials. Qi Bo, Hua Tuo, Bian Que, Sun Simiao and Wei Cizang were recorded as Yaowang in three places, and Sun Simiao was enshrined in two of them. The architectural pattern of Yaowang Temple varies greatly from three courtyards to natural caves. Local chronicles contain all kinds of legends and stories about the Yaowang, which is a concrete embodiment of the belief in Yaowang. The belief in Yaowang not only carries people's thirst for health, but also prays for good weather.
Language	Chinese
Publishing date	2024-03-06
Publishing country	China
Document type	English Abstract ; Journal Article
ZDB-ID	1052411-3
ISSN	0255-7053
ISSN	0255-7053
DOI	10.3760/cma.j.cn112155-20230918-00030
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Article ; Online: The impact of users' trust on intention to use the mobile medical platform: Evidence from China.

He, Jinjiang

Frontiers in public health

2023 Volume 11, Page(s) 1076367

Abstract: Introduction: The mobile medical platform effectively complements offline medical services as it can provide patients with broader and more convenient medical services, effectively solving the shortage of medical resources in the public health system. ... ...

Abstract	Introduction: The mobile medical platform effectively complements offline medical services as it can provide patients with broader and more convenient medical services, effectively solving the shortage of medical resources in the public health system. Although the public interest in healthcare service platforms continues to rise, the market data shows that the adoption and acceptance have not reached a high level. How to increase the utilization rate of the mobile medical platform to relieve medical pressure has become an urgent issue to be discussed. Based on the framework of "trust-intention" this research introduces innovation acceptance and technical risk concerns as the two moderating variables to attempt to build a research model of users' intention to use the mobile medical platform. The analysis illustrated that users' trust in the mobile medical platform would positively affect their use intention. The researchers further explored the moderating role of innovation acceptance and technical risk concerns. Methods: Use questionnaire to collect data in China, then use the OLS least square method for the regression test. Results: The results showed that users with high personal innovation acceptance would positively promote the relationship between trust and use intention. In contrast, users who are more concerned about the risks of innovative technologies will weaken the relationship between trust and use intention. Discussion: The findings theoretically extend the academic research of use intention to the specific context of the mobile medical platform and enrich the research framework of "trust-intention".
MeSH term(s)	Humans ; Intention ; Trust ; Telemedicine/methods ; China ; Surveys and Questionnaires
Language	English
Publishing date	2023-03-21
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2711781-9
ISSN	2296-2565 ; 2296-2565
ISSN (online)	2296-2565
ISSN	2296-2565
DOI	10.3389/fpubh.2023.1076367
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Article ; Online: Integration degree of China's the new development pattern of dual circulation and industrial green development.

He, Jianlin

PloS one

2023 Volume 18, Issue 7, Page(s) e0288160

Abstract: The long-standing development pattern dominated by international circulation makes China face the risk of "low-end lock-in" and "being decoupling". In addition, the current global climate change and environmental crisis are becoming increasingly severe, ... ...

Abstract	The long-standing development pattern dominated by international circulation makes China face the risk of "low-end lock-in" and "being decoupling". In addition, the current global climate change and environmental crisis are becoming increasingly severe, coupled with the COVID-19 impact. Chinese enterprises must actively build a green development system for domestic industries in a mutually reinforcing manner in the context of the domestic general circulation, in order to adapt to the new dual circulation environment as soon as possible. This paper analyzes the specific coupling and coordination relationship between the two systems based on the relevant data of China's three major industries from 2008-2014 using Index DEA, entropy value method, gray correlation analysis and coupling coordination model. The results of the study show that: the two systems of dual circulation pattern and industrial green development have a strong correlation and basically present a coupling relationship, but within the industry, there is a problem of the collapse of the tertiary industry. In terms of the type of coupling, the domestic and international circulation in general gradually present the green development leading state, except for the primary industrial segment of the international circulation. On the whole, the coupling quality of the two systems needs to be further improved. Based on this, this paper puts forward the following suggestions: (1) coordinate the internal and external development of the industry; (2) take innovation as the driving force to promote the green transformation of industries; (3) take green sharing as the goal to strengthen the policy orientation of green development; (4) take the opportunity of mutual promotion of dual circulation to stabilize the steady state of green development coupling.
MeSH term(s)	Humans ; Sustainable Development ; COVID-19/epidemiology ; Industrial Development ; Industry ; China ; Economic Development
Language	English
Publishing date	2023-07-07
Publishing country	United States
Document type	Journal Article
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0288160
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Book ; Online: CyberCardia

He, Jiyue

Patient-specific electrophysiological heart model for assisting left atrium arrhythmia ablation

2024

Abstract: Atrial arrhythmia can be categorized into tachycardia, flutter, and fibrillation. Atrial fibrillation is a prevalent heart disease that results in weak and irregular contractions of the atria. It affects millions people worldwide and contributes to ... ...

Abstract	Atrial arrhythmia can be categorized into tachycardia, flutter, and fibrillation. Atrial fibrillation is a prevalent heart disease that results in weak and irregular contractions of the atria. It affects millions people worldwide and contributes to hundreds of thousands deaths annually. Cardiac ablation is among the most successful treatment options, involving the use of radio frequency energy to kill diseased cells or create lesion lines that obstruct abnormal activation waves. During the procedure, catheters are inserted into the left atrium to map the atrium geometry and record endocardium electrograms that are then converted into electroanatomical maps to pinpoint the arrhythmia source locations. However, identifying these sources is challenging. The electrograms are asynchronous and can be susceptible to noise. The spatial distribution of sampling sites is non-uniform, which leads to inaccurate maps. Identifying arrhythmia source locations is not a trivial task. Therefore, an ablation procedure often lasts from 3 to 6 hours, and arrhythmia recurrence within 12 months after first ablation is around 50%. To address these challenges, we developed an integrated computational heart mode for clinical left atrium arrhythmia ablation. Our system takes in the left atrium geometry and electrograms, processes them to extract regional tissue properties, which are used to tune a heart model, creating a patient-specific whole-atrium model. With this model, we can simulate and detect arrhythmia sources, and provide ablation assistance. To build such a system, we investigated the fiber effects on atrial activation patterns. We developed a fast heart model tuning method which takes only a few seconds of computation time on a personal computer, enabling real-time assistance during the ablation procedure. We achieved high accuracy in simulating arrhythmias, which we validated on patient data. Comment: PhD thesis
Keywords	Physics - Medical Physics
Subject code	616
Publishing date	2024-01-06
Publishing country	us
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Baicalin mitigated IL-1β-Induced osteoarthritis chondrocytes damage through activating mitophagy.

He, Jun / He, Jian

Chemical biology & drug design

2023 Volume 101, Issue 6, Page(s) 1322–1334

Abstract: Mitophagy is related to chondrocyte homeostasis and plays a key role in the progress of osteoarthritis (OA). Baicalin has a protective effect on OA chondrocytes, the aim of this study was to explore whether the effect of Baicalin on IL-1β-induced ... ...

Abstract	Mitophagy is related to chondrocyte homeostasis and plays a key role in the progress of osteoarthritis (OA). Baicalin has a protective effect on OA chondrocytes, the aim of this study was to explore whether the effect of Baicalin on IL-1β-induced chondrocyte injury is related to the regulation of mitophagy. The expression of collagen II in chondrocytes was detected to identify chondrocytes. The effects of different concentrations of Baicalin (10, 20 and 40 μM), autophagy inhibitor (3-Methyladenine), autophagy activator (rapamycin) and Baicalin combined with PI3K agonist (740Y-P) on the viability (cell counting kit 8), apoptosis (flow cytometry), autophagy activation (Monodansylcadaverine staining) and mitochondrial membrane potential (JC-1 kit) of IL-1β-induced chondrocytes were evaluated. The co-localization of autophagosome and mitochondria was determined by immunofluorescence. Apoptosis-, autophagy-, PI3K/AKT/mTOR pathway- and mitophagy-related proteins were detected by western blot. Our result revealed that Baicalin and rapamycin facilitated cell viability, autophagy and mitophagy, elevated mitochondrial membrane potential and suppressed apoptosis of IL-1β-induced rat chondrocytes. In addition, Baicalin and rapamycin upregulated the levels of Bcl-2, Beclin 1, LC3-II/LC3-I, p-Drp1, PINK1 and Parkin as well as downregulated the levels of Bax, cleaved caspase-3, P62, p-PI3K/PI3K, p-mTOR/mTOR and Drp1 in IL-1β-induced rat chondrocytes. However, 3-Methyladenine did the opposite effects of Baicalin and 740Y-P reversed the effects of Baicalin on IL-1β-induced rat chondrocytes. In conclusion, Baicalin activated mitophagy in IL-1β-induced chondrocytes by inhibiting PI3K/AKT/mTOR pathway and activating PINK1/Parkin and PINK1/Drp-1 pathway, thereby reducing the chondrocyte injury.
MeSH term(s)	Animals ; Rats ; Apoptosis ; Chondrocytes/metabolism ; Interleukin-1beta/metabolism ; Mitophagy ; Osteoarthritis/drug therapy ; Osteoarthritis/metabolism ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Signal Transduction ; TOR Serine-Threonine Kinases/metabolism ; Ubiquitin-Protein Ligases/metabolism ; Ubiquitin-Protein Ligases/pharmacology
Chemical Substances	baicalin (347Q89U4M5) ; Interleukin-1beta ; Phosphatidylinositol 3-Kinases (EC 2.7.1.-) ; Proto-Oncogene Proteins c-akt (EC 2.7.11.1) ; TOR Serine-Threonine Kinases (EC 2.7.11.1) ; Ubiquitin-Protein Ligases (EC 2.3.2.27) ; 740Y-P
Language	English
Publishing date	2023-03-05
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2216600-2
ISSN	1747-0285 ; 1747-0277
ISSN (online)	1747-0285
ISSN	1747-0277
DOI	10.1111/cbdd.14215
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Article ; Online: Algorithm Composition and Emotion Recognition Based on Machine Learning.

He, Jiao

Computational intelligence and neuroscience

2022 Volume 2022, Page(s) 1092383

Abstract: This paper proposes a new algorithm composition network from the perspective of machine learning, based on an in-depth study of related literature. At the same time, this paper examines the characteristics of music and develops a model for recognising ... ...

Abstract	This paper proposes a new algorithm composition network from the perspective of machine learning, based on an in-depth study of related literature. At the same time, this paper examines the characteristics of music and develops a model for recognising musical emotions. Using the model's information entropy of pitch and intensity to extract the main melody track, note features are extracted from bar features. Finally, the cosine of the vector included angle is used to judge the similarity between feature vectors of several adjacent sections, allowing the music to be divided into several independent segments. The emotional model of music is used to analyze each segment's emotion. By quantifying music features, this paper classifies and quantifies music emotion based on the mapping relationship between music features and emotion. Music emotion can be accurately identified by the model. The model's emotion recognition accuracy is up to 93.78 percent, and the algorithm's recall rate is up to 96.3 percent, according to simulation results. The recognition method used in this paper has a higher recognition ability than other methods, and the emotion recognition result is more reliable. This paper can not only meet the composer's auxiliary creative needs, but it can also help intelligent music services.
MeSH term(s)	Algorithms ; Emotions ; Machine Learning ; Music/psychology ; Recognition, Psychology
Language	English
Publishing date	2022-06-06
Publishing country	United States
Document type	Journal Article
ZDB-ID	2388208-6
ISSN	1687-5273 ; 1687-5273
ISSN (online)	1687-5273
ISSN	1687-5273
DOI	10.1155/2022/1092383
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Article: Creatinine-to-body weight ratio is a predictor of incident diabetes: a population-based retrospective cohort study.

He, Jiacheng

Diabetology & metabolic syndrome

2022 Volume 14, Issue 1, Page(s) 7

Abstract: Purpose: Creatinine to body weight (Cre/BW) ratio is considered the independent risk factor for incident type 2 diabetes mellitus (T2DM), but research on this relationship is limited. The relationship between the Cre/BW ratio and T2DM among Chinse ... ...

Abstract	Purpose: Creatinine to body weight (Cre/BW) ratio is considered the independent risk factor for incident type 2 diabetes mellitus (T2DM), but research on this relationship is limited. The relationship between the Cre/BW ratio and T2DM among Chinse individuals is still ambiguous. This study aimed to evaluate the correlation between the Cre/BW ratio and the risk of T2DM in the Chinese population. Methods: This is a retrospective cohort study from a prospectively collected database. We included a total of 200,658 adults free of T2DM at baseline. The risk of incident T2DM according to Cre/BW ratio was estimated using multivariable Cox proportional hazards models, and a two-piece wise linear regression model was developed to find out the threshold effect. Results: With a median follow-up of 3.13 ± 0.94 years, a total of 4001 (1.99%) participants developed T2DM. Overall, there was an L-shaped relation of Cre/BW ratio with the risk of incident T2DM (P for non-linearity < 0.001). When the Cre/BW ratio (× 100) was less than 0.86, the risk of T2DM decreased significantly as the Cre/BW ratio increased [0.01 (0.00, 0.10), P < 0.001]. When the Cre/BW ratio (× 100) was between 0.86 and 1.36, the reduction in the risk of developing T2DM was not as significant as before [0.22 (0.12, 0.38), P < 0.001]. In contrast, when the Cre/BW ratio (× 100) was greater than 1.36, the reduction in T2DM incidence became significantly flatter than before [0.73 (0.29,1.8), P = 0.49]. Conclusion: There was an L-shaped relation of Cre/BW ratio with incidence of T2DM in general Chinese adults. A negative curvilinear association between Cre/BW ratio and incident T2DM was present, with a saturation effect predicted at 0.86 and 1.36 of Cre/BW ratio (× 100).
Language	English
Publishing date	2022-01-15
Publishing country	England
Document type	Journal Article
ZDB-ID	2518786-7
ISSN	1758-5996
ISSN	1758-5996
DOI	10.1186/s13098-021-00776-8
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