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  1. Article ; Online: Research Progress in the Epidemiology of HIV/AIDS in China.

    He, Na

    China CDC weekly

    2021  Volume 3, Issue 48, Page(s) 1022–1030

    Abstract: After thirty-two years since the first domestic outbreak of human immunodeficiency virus (HIV)/ acquired immune deficiency syndrome (AIDS) among injection drug users (IDUs) and almost two decades of comprehensive response efforts by the Chinese ... ...

    Abstract After thirty-two years since the first domestic outbreak of human immunodeficiency virus (HIV)/ acquired immune deficiency syndrome (AIDS) among injection drug users (IDUs) and almost two decades of comprehensive response efforts by the Chinese government, HIV/AIDS remains a major public health problem. The increasing burden of HIV/AIDS and comorbidities, the emergence of new HIV subtypes and/or circulating recombinant forms and drug mutations, the changing transmission networks, and the urgency of immediate antiretroviral therapy initiation upon an HIV diagnosis are increasingly challenging and altogether likely to have significant impact on the HIV epidemic in China. Upon the call for the global AIDS response to end AIDS by 2030, China needs to develop an innovative and pragmatic roadmap to address these challenges. This review is intended to provide a succinct overview of what China has done in efforts to achieve the global goal of ending AIDS by 2030 and the recently proposed "95-95-95-95" target (95% combination prevention, 95% detection, 95% treatment, 95% viral suppression), and to summarize the most recent progresses in the epidemiological research of HIV/AIDS in China with the aim of providing insights on the next generation of HIV control and prevention approaches and to shed light on upgrading the national strategy to end AIDS in this country.
    Language English
    Publishing date 2021-02-15
    Publishing country China
    Document type Journal Article
    ISSN 2096-7071
    ISSN (online) 2096-7071
    DOI 10.46234/ccdcw2021.249
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Rapid evolution of the COVID-19 pandemic calls for a unified public health response.

    He, Na

    Bioscience trends

    2021  Volume 15, Issue 4, Page(s) 196–200

    Abstract: The globe has witnessed the rapid evolution of SARS-CoV-2 mutations and emerging variants of concern (VOCs) and variants of interest (VOIs) that have broadly impacted the transmissibility, antigenicity, morbidity, and mortality of the virus. Although ... ...

    Abstract The globe has witnessed the rapid evolution of SARS-CoV-2 mutations and emerging variants of concern (VOCs) and variants of interest (VOIs) that have broadly impacted the transmissibility, antigenicity, morbidity, and mortality of the virus. Although around 2.5 billion vaccine doses have been administered worldwide, vaccine coverage remains far behind the minimum threshold needed to achieve herd immunity overall and it varies substantially by country. Many countries, and especially low- and middle-income countries (LMICs), are struggling with access to COVID-19 vaccines and a lack of personnel to perform mass vaccination. Effective nonpharmaceutical interventions (NPIs) are also not unanimously accepted and strictly complied with by the public and local communities. Moreover, the global fight against COVID-19 is and continues to face geopolitical, social, economic, and human rights concerns. Taken together, these circumstances call for a unified public health response with well-organized individual, local, national, and global efforts and actions to achieve success in controlling the COVID-19 pandemic and achieving sustainable health and development goals.
    MeSH term(s) COVID-19/epidemiology ; COVID-19/prevention & control ; COVID-19/therapy ; COVID-19 Vaccines/administration & dosage ; Communicable Disease Control ; Humans ; Pandemics ; SARS-CoV-2/classification ; SARS-CoV-2/genetics
    Chemical Substances COVID-19 Vaccines
    Language English
    Publishing date 2021-07-01
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 2543899-2
    ISSN 1881-7823 ; 1881-7815
    ISSN (online) 1881-7823
    ISSN 1881-7815
    DOI 10.5582/bst.2021.01261
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Comment: Effects of virtual reality on preoperative anxiety in children: A systematic review and meta-analysis of randomised controlled trials.

    He, Na / Tan, Xiaoxue

    Journal of clinical nursing

    2023  Volume 33, Issue 2, Page(s) 768–769

    MeSH term(s) Child ; Humans ; Anxiety/prevention & control ; Anxiety Disorders ; Virtual Reality ; Virtual Reality Exposure Therapy ; Randomized Controlled Trials as Topic
    Language English
    Publishing date 2023-08-16
    Publishing country England
    Document type Meta-Analysis ; Systematic Review ; Letter
    ZDB-ID 1159483-4
    ISSN 1365-2702 ; 0962-1067 ; 1752-9816
    ISSN (online) 1365-2702
    ISSN 0962-1067 ; 1752-9816
    DOI 10.1111/jocn.16844
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Amoxicillin-Clavulanate vs Amoxicillin for Pediatric Acute Sinusitis.

    He, Na / Ying, Yingqiu / Cheng, Yinchu

    JAMA

    2024  Volume 331, Issue 3, Page(s) 257–258

    MeSH term(s) Child ; Humans ; Amoxicillin/therapeutic use ; Amoxicillin-Potassium Clavulanate Combination/therapeutic use ; Sinusitis/drug therapy ; Acute Disease ; Drug Combinations ; Anti-Bacterial Agents/therapeutic use
    Chemical Substances Amoxicillin (804826J2HU) ; Amoxicillin-Potassium Clavulanate Combination (74469-00-4) ; Drug Combinations ; Anti-Bacterial Agents
    Language English
    Publishing date 2024-01-16
    Publishing country United States
    Document type Comparative Study ; Letter ; Comment
    ZDB-ID 2958-0
    ISSN 1538-3598 ; 0254-9077 ; 0002-9955 ; 0098-7484
    ISSN (online) 1538-3598
    ISSN 0254-9077 ; 0002-9955 ; 0098-7484
    DOI 10.1001/jama.2023.23642
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Effects of innovative reinforced concrete slit shaft configuration on seismic performance of elevated water tanks.

    Gurkalo, Filip / He, Chaofan / Poutos, Konstantinos / He, Na

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 6113

    Abstract: Elevated water tanks are considered crucial infrastructure due to their significant role in supporting essential services. A strong ground motion may result in a failure or significant damage to a reinforced concrete shaft of an elevated water tank ... ...

    Abstract Elevated water tanks are considered crucial infrastructure due to their significant role in supporting essential services. A strong ground motion may result in a failure or significant damage to a reinforced concrete shaft of an elevated water tank because hysteric energy dissipation is limited to the formation of plastic hinges at the base of the shaft, while the nonlinear properties of the rest of the shaft remain underutilised. The innovative system of assembling RC shafts for elevated water tanks using a slit wall technique was developed to enhance energy dissipation along with the shaft height by introducing slit zones. The comparative nonlinear dynamic analysis between three-dimensional models of elevated water tanks with different shaft diameters and heights was conducted using SAP2000 software. The results of elevated water tanks with slit and solid reinforced concrete shafts were compared. The research findings showed that during a seismic event, the slit zones increased the ductility of the shaft, reduced stress concentration in the lower part of the shaft, and provided uniform stress distribution throughout the shaft's height. The effect of the innovative system is especially noticeable in the elevated water tanks with tall and slender shafts.
    Language English
    Publishing date 2024-03-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-56851-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Advances in research of multimorbidity among HIV-positive individuals

    MA Zhonghui / DING Yingying / HE Na

    Shanghai yufang yixue, Vol 35, Iss 1, Pp 78-

    2023  Volume 82

    Abstract: Multimorbidity is the co‑existing of two or more chronic diseases or health problems. Widespread access to antiretroviral therapy has led to a marked improvement in the immune status and life expectancy among HIV-positive individuals. HIV-positive ... ...

    Abstract Multimorbidity is the co‑existing of two or more chronic diseases or health problems. Widespread access to antiretroviral therapy has led to a marked improvement in the immune status and life expectancy among HIV-positive individuals. HIV-positive individuals suffer from higher burden of chronic non-communicable diseases and are more likely to show a premature aging and frailty trend compared with the general population. The consequent increase in the prevalence of multimorbidity leads to the increasing in medical and economic burden, and different comorbidity patterns may indicate different risk factors and have different effects on health outcomes, posing challenges to healthcare and comprehensive management for HIV-positive individuals. This review summarizes research advances in prevalence, associated factors and patterns of comorbidities among HIV-positive individuals.
    Keywords human immunodeficiency virus(hiv) ; multimorbidity ; associated factor ; comorbidity pattern ; Medicine ; R
    Subject code 306
    Language Chinese
    Publishing date 2023-01-01T00:00:00Z
    Publisher Shanghai Preventive Medicine Association
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Association of SOX6 gene polymorphisms with Kashin-Beck disease risk in the Chinese Han population

    He Na / Hong Aiwen / Zhao Kun / Zhang Zhefan / Wang Shengli / Jia Yaofei

    Open Medicine, Vol 19, Iss 1, Pp 1732-

    2024  Volume 8

    Abstract: Kashin-Beck disease (KBD) is an endemic osteochondropathy. A specific gene called SRY-box transcription factor 6 (SOX6) is important for forming cartilage. This study aims to explore the potential correlation between SOX6 single nucleotide polymorphisms ( ...

    Abstract Kashin-Beck disease (KBD) is an endemic osteochondropathy. A specific gene called SRY-box transcription factor 6 (SOX6) is important for forming cartilage. This study aims to explore the potential correlation between SOX6 single nucleotide polymorphisms (SNPs) and KBD risk for the first time. In the case–control study, 735 unrelated Chinese Han individuals were enrolled. The four mutation sites of the SOX6 gene (rs4539287 G/A, rs3203295 C/A, rs7928675 C/A, and rs10832681 A/G) were screened and genotyped on the Agena MassARRAY platform. The correlation between SOX6 SNPs and KBD risk was explored based on logistic regression analysis. The interaction between SNP and SNP was analyzed based on the multi-factor dimensionality reduction (MDR) method. Overall analysis revealed a remarkable correlation between rs7928675 and rs10832681 and the reduction of KBD risk (p < 0.05). Subgroup analyses further indicated that these two SNPs have a significant protective effect on KBD risk among participants aged ≤65 years, males, and non-smokers (p < 0.05). MDR displayed a marked interaction between rs3203295 and rs10832681. Our study revealed that SOX6 rs7928675 and rs10832681 are markedly correlated with a reduced risk of KBD in the Chinese Han population, providing a new direction for the prevention, diagnosis, and treatment of KBD.
    Keywords kashin-beck disease ; risk ; sox6 ; snps ; case–control study ; Medicine ; R
    Subject code 610
    Language English
    Publishing date 2024-01-01T00:00:00Z
    Publisher De Gruyter
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Home bias and local equity portfolio decisions of Chinese insurance institutional investors.

    Yang, Shanshan / He, Na / Yu, Haizong

    PloS one

    2023  Volume 18, Issue 7, Page(s) e0288250

    Abstract: Our paper explores whether Chinese insurance companies exhibit a local preference in deciding their equity portfolios and the incentive of this preference. Our research finds that Chinese insurance institutional investors significantly tilt to invest in ... ...

    Abstract Our paper explores whether Chinese insurance companies exhibit a local preference in deciding their equity portfolios and the incentive of this preference. Our research finds that Chinese insurance institutional investors significantly tilt to invest in local firms geographically close to them, and local investments do not significantly outperform non-local investments. The results indicate that the behavioral aspect of home bias, rather than information advantage, play a more significant role in deciding equity holdings of China's insurance companies. Additionally, local equity preference is more pronounced in dialect-segmented areas and life insurance firms. This paper incorporates hometown identification into the analysis framework of insurance companies' portfolio decision-making and enriches the research of their investing strategies from the perspective of behavioral finance.
    Language English
    Publishing date 2023-07-14
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0288250
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: How Do We Credit the Evidence Generated From Subgroup Analyses in Randomized Clinical Trials?

    Cheng, Yinchu / He, Na / Yan, Yingying

    JAMA cardiology

    2023  Volume 8, Issue 6, Page(s) 623

    MeSH term(s) Humans ; Randomized Controlled Trials as Topic ; Data Interpretation, Statistical
    Language English
    Publishing date 2023-04-19
    Publishing country United States
    Document type Journal Article ; Comment
    ISSN 2380-6591
    ISSN (online) 2380-6591
    DOI 10.1001/jamacardio.2023.0668
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: DCSAU-Net: A deeper and more compact split-attention U-Net for medical image segmentation.

    Xu, Qing / Ma, Zhicheng / He, Na / Duan, Wenting

    Computers in biology and medicine

    2023  Volume 154, Page(s) 106626

    Abstract: Deep learning architecture with convolutional neural network achieves outstanding success in the field of computer vision. Where U-Net has made a great breakthrough in biomedical image segmentation and has been widely applied in a wide range of practical ...

    Abstract Deep learning architecture with convolutional neural network achieves outstanding success in the field of computer vision. Where U-Net has made a great breakthrough in biomedical image segmentation and has been widely applied in a wide range of practical scenarios. However, the equal design of every downsampling layer in the encoder part and simply stacked convolutions do not allow U-Net to extract sufficient information of features from different depths. The increasing complexity of medical images brings new challenges to the existing methods. In this paper, we propose a deeper and more compact split-attention u-shape network, which efficiently utilises low-level and high-level semantic information based on two frameworks: primary feature conservation and compact split-attention block. We evaluate the proposed model on CVC-ClinicDB, 2018 Data Science Bowl, ISIC-2018, SegPC-2021 and BraTS-2021 datasets. As a result, our proposed model displays better performance than other state-of-the-art methods in terms of the mean intersection over union and dice coefficient. More significantly, the proposed model demonstrates excellent segmentation performance on challenging images. The code for our work and more technical details can be found at https://github.com/xq141839/DCSAU-Net.
    MeSH term(s) Neural Networks, Computer ; Semantics ; Image Processing, Computer-Assisted
    Language English
    Publishing date 2023-02-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 127557-4
    ISSN 1879-0534 ; 0010-4825
    ISSN (online) 1879-0534
    ISSN 0010-4825
    DOI 10.1016/j.compbiomed.2023.106626
    Database MEDical Literature Analysis and Retrieval System OnLINE

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