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  1. Book ; Online ; E-Book: Vascular mechanobiology in physiology and disease

    Hecker, Markus / Duncker, Dirk J.

    (Cardiac and vascular biology ; 8)

    2021  

    Author's details Markus Hecker, Dirk J. Duncker editors
    Series title Cardiac and vascular biology ; 8
    Collection
    Keywords Electronic books
    Language English
    Size 1 Online-Ressource (xi, 352 Seiten), Illustrationen, Diagramme
    Publisher Springer
    Publishing place Cham
    Publishing country Switzerland
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT020880111
    ISBN 978-3-030-63164-2 ; 9783030631635 ; 3-030-63164-8 ; 303063163X
    DOI 10.1007/978-3-030-63164-2
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Thesis: 15-deoxy-Δ12,14-Prostaglandin J2 als Kompensationsmechanismus der endothelialen Dysfunktion bei Patienten mit koronarer Herzkrankheit

    Turinsky, Martin / Hecker, Markus

    2021  

    Title variant 15-deoxy-Delta12,14-Prostaglandin J2 als Kompensationsmechanismus der endothelialen Dysfunktion bei Patienten mit koronarer Herzkrankheit
    Institution Universität Heidelberg
    Author's details vorgelegt von Martin Turinsky ; Doktorvater: Prof. Dr. Markus Hecker
    Language German
    Size 70 Blätter, Illustrationen, Diagramme, 12 cm
    Publishing place Heidelberg
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Ruprecht-Karls-Universität Heidelberg, 2021
    Note Im Titel sind die Zahlen 12 und 14 hochgestellt, die Zahl 2 ist tiefgestellt
    Accompanying material Beiheft
    HBZ-ID HT021213805
    Database Catalogue ZB MED Medicine, Health

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  3. Book ; Thesis: Immunological mechanism of allergic colitis

    Rothenberger, Raphael / Hecker, Markus

    2021  

    Institution Universität Heidelberg
    Author's details vorgelegt von Raphael Rothenberger ; Doktorvater: Herr Prof. Dr. Markus Hecker
    Language English
    Size vi, 57 Blätter, Illustrationen, Diagramme
    Publishing place Heidelberg
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Ruprecht-Karls-Universität Heidelberg, 2021
    Note Text auf Englisch, Zusammenfassung auf Englisch und Deutsch
    HBZ-ID HT021379317
    Database Catalogue ZB MED Medicine, Health

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  4. Book ; Thesis: Modulation of electrical signal propagation in stem cell-derived cardiomyocytes as a novel model for arrhythmogenic cardiomyopathies

    Ke, Xijian / Hecker, Markus

    2021  

    Institution Universität Heidelberg
    Author's details vorgelegt von Xijian Ke ; Doktorvater: Prof. Dr. Markus Hecker
    Language German
    Size 66 Blätter, Illustrationen, Diagramme
    Publishing place Heidelberg
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Ruprecht-Karls-Universität Heidelberg, 2022
    Note Text Englisch, Zusammenfassung in englischer und deutscher Sprache
    HBZ-ID HT030032093
    Database Catalogue ZB MED Medicine, Health

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  5. Book ; Thesis: Chronisch oxidativer Stress reguliert durch Induktion der mikroRNA-1 die Connexin-43-Expression in einem neuen Zellmodell ventrikulärer Arrhythmien

    Wahl, Carl-Mattheis / Hecker, Markus

    2022  

    Institution Universität Heidelberg
    Author's details vorgelegt von Carl-Mattheis Martin Wahl ; Doktorvater: Prof. Dr. Markus Hecker
    Language German
    Size V, 95 Blätter, Illustrationen, Diagramme
    Publishing place Heidelberg
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Ruprecht-Karls-Universität Heidelberg, 2022
    HBZ-ID HT030727523
    Database Catalogue ZB MED Medicine, Health

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  6. Book ; Thesis: Die Beeinflussung der Stickstoffmonoxid (NO)-Synthese in Endothelzellen durch a-Tocopherol [Alpha-Tocopherol] und sein kurzkettiges Derivat Trolox

    Hecker, Martin

    2009  

    Author's details von Martin Hecker
    Subject code 615.3
    Language German
    Size XII, 86 Bl., Ill., graph. Darst.
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Jena, Univ., Diss., 2009
    HBZ-ID HT016344412
    Database Catalogue ZB MED Medicine, Health

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  7. Book ; Thesis: Epidemiologische Studie über die Verbreitung der Karies unter farbigen und schwarzen Grundschülern im Großraum Kapstadt/Südafrika

    Hecker, Marcus

    2008  

    Author's details vorgelegt von Marcus Hecker
    Language German
    Size 105 S. : Ill., graph. Darst.
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Aachen, Techn. Hochsch., Diss., 2008
    HBZ-ID HT015495056
    Database Catalogue ZB MED Medicine, Health

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  8. Book ; Thesis: Ecto-5'-Nuleotidase (CD73) inhibits vascular inflammation during vein graft remodeling

    Lanzer, Jan David / Hecker, Markus

    2018  

    Institution Universität Heidelberg
    Author's details vorgelegt von Jan David Lanzer ; Doktorvater: Herr Prof. Dr. Markus Hecker, wissenschaftlicher Betreuer: Herr Dr. med. Manfred Boehm
    Language English
    Size 88 Blätter, Illustrationen, Diagramme, 30 cm
    Publishing place Heidelberg
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Ruprecht-Karls-Universität Heidelberg, 2018
    HBZ-ID HT020463247
    Database Catalogue ZB MED Medicine, Health

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  9. Article ; Online: Potential role of soluble CD40 receptor in chronic inflammatory diseases.

    Wagner, A H / Klersy, A / Sultan, C S / Hecker, M

    Biochemical pharmacology

    2023  Volume 217, Page(s) 115858

    Abstract: The CD40 receptor and its ligand CD154 are widely expressed in various immune-competent cells. Interaction of CD154 with CD40 is essential for B-cell growth, differentiation, and immunoglobulin class switching. Many other immune-competent cells involved ... ...

    Abstract The CD40 receptor and its ligand CD154 are widely expressed in various immune-competent cells. Interaction of CD154 with CD40 is essential for B-cell growth, differentiation, and immunoglobulin class switching. Many other immune-competent cells involved in innate and adaptive immunity communicate through this co-stimulatory ligand-receptor dyad. CD40-CD154 interaction is involved in the pathogenesis of numerous inflammatory and autoimmune diseases. While CD40 and CD154 are membrane-bound proteins, their soluble counterparts are generated by proteolytic cleavage or alternative splicing. This review summarises current knowledge about the impact of single nucleotide polymorphisms in the human CD40 gene and compensatory changes in the plasma level of the soluble CD40 receptor (sCD40) isoform in related pro-inflammatory diseases. It discusses regulation patterns of the disintegrin metalloprotease ADAM17 function leading to ectodomain shedding of transmembrane proteins, such as pro-inflammatory adhesion molecules or CD40. The role of sCD40 as a potential biomarker for chronic inflammatory diseases will also be discussed.
    MeSH term(s) Humans ; Ligands ; CD40 Antigens/genetics ; CD40 Antigens/metabolism ; CD40 Ligand/genetics ; CD40 Ligand/metabolism ; Chronic Disease ; Membrane Proteins
    Chemical Substances Ligands ; CD40 Antigens ; CD40 Ligand (147205-72-9) ; Membrane Proteins
    Language English
    Publishing date 2023-10-18
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 208787-x
    ISSN 1873-2968 ; 0006-2952
    ISSN (online) 1873-2968
    ISSN 0006-2952
    DOI 10.1016/j.bcp.2023.115858
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Blood transcriptome profiling captures dysregulated pathways and response to treatment in neuroimmunological disease.

    Hecker, Michael

    EBioMedicine

    2019  Volume 49, Page(s) 2–3

    MeSH term(s) Gene Expression Profiling ; Humans ; Interferon-beta ; Multiple Sclerosis ; Neuroprotection ; Transcriptome
    Chemical Substances Interferon-beta (77238-31-4)
    Language English
    Publishing date 2019-10-24
    Publishing country Netherlands
    Document type Journal Article ; Comment
    ZDB-ID 2851331-9
    ISSN 2352-3964
    ISSN (online) 2352-3964
    DOI 10.1016/j.ebiom.2019.10.035
    Database MEDical Literature Analysis and Retrieval System OnLINE

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