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  1. Article ; Online: Coping With the "Small Sample-Small Relevant Effects" Dilemma in Elite Sport Research.

    Skorski, Sabrina / Hecksteden, Anne

    International journal of sports physiology and performance

    2021  Volume 16, Issue 11, Page(s) 1559–1560

    MeSH term(s) Adaptation, Psychological ; Athletes ; Humans ; Sports
    Language English
    Publishing date 2021-10-15
    Publishing country United States
    Document type Editorial
    ISSN 1555-0273
    ISSN (online) 1555-0273
    DOI 10.1123/ijspp.2021-0467
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Why Humble Farmers May in Fact Grow Bigger Potatoes: A Call for Street-Smart Decision-Making in Sport.

    Hecksteden, Anne / Keller, Niklas / Zhang, Guangze / Meyer, Tim / Hauser, Thomas

    Sports medicine - open

    2023  Volume 9, Issue 1, Page(s) 94

    Abstract: Background: The main task of applied sport science is to inform decision-making in sports practice, that is, enabling practitioners to compare the expectable outcomes of different options (e.g. training programs).: Main body: The "evidence" provided ... ...

    Abstract Background: The main task of applied sport science is to inform decision-making in sports practice, that is, enabling practitioners to compare the expectable outcomes of different options (e.g. training programs).
    Main body: The "evidence" provided may range from group averages to multivariable prediction models. By contrast, many decisions are still largely based on the subjective, experience-based judgement of athletes and coaches. While for the research scientist this may seem "unscientific" and even "irrational", it is important to realize the different perspectives: science values novelty, universal validity, methodological rigor, and contributions towards long-term advancement. Practitioners are judged by the performance outcomes of contemporary, specific athletes. This makes out-of-sample predictive accuracy and robustness decisive requirements for useful decision support. At this point, researchers must concede that under the framework conditions of sport (small samples, multifactorial outcomes etc.) near certainty is unattainable, even with cutting-edge methods that might theoretically enable near-perfect accuracy. Rather, the sport ecosystem favors simpler rules, learning by experience, human judgement, and integration across different sources of knowledge. In other words, the focus of practitioners on experience and human judgement, complemented-but not superseded-by scientific evidence is probably street-smart after all. A major downside of this human-driven approach is the lack of science-grade evaluation and transparency. However, methods are available to merge the assets of data- and human-driven strategies and mitigate biases.
    Short conclusion: This work presents the challenges of learning, forecasting and decision-making in sport as well as specific opportunities for turning the prevailing "evidence vs. eminence" contrast into a synergy.
    Language English
    Publishing date 2023-10-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2809942-4
    ISSN 2198-9761 ; 2199-1170
    ISSN (online) 2198-9761
    ISSN 2199-1170
    DOI 10.1186/s40798-023-00641-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Dealing with small samples in football research.

    Hecksteden, Anne / Kellner, Ralf / Donath, Lars

    Science & medicine in football

    2021  Volume 6, Issue 3, Page(s) 389–397

    Abstract: In football research, 'small' trials with low statistical power are common. On the elite level, the inherently low number of participants obviously conflicts with the relevance of even tiny effects. However, general characteristics of football also ... ...

    Abstract In football research, 'small' trials with low statistical power are common. On the elite level, the inherently low number of participants obviously conflicts with the relevance of even tiny effects. However, general characteristics of football also contribute (e.g. multifactorially influenced and/or complex outcomes). Importantly, small sample sizes are problematic regardless of the study outcome with issues ranging from inconclusive results and low precision to unrepeatable 'discoveries' and overestimation of effect sizes. Therefore, meeting the calculated, target sample size is the first priority. If a suboptimal sample size must be accepted, a range of tools can improve insights. To begin with, some general aspects of data collection and analysis become more important and should be optimally implemented (e.g. reliability of measures). Building on this foundation, specific amendments are available on the levels of data collection (e.g. aggregated single-subject designs) and data analysis (e.g. Bayesian methods). The present commentary aims to give an overview of selected, practical tools for dealing with small sample sizes in football research and provide recommendations for their application in scenarios typical for the field. Importantly, versatility and adaptability are mirrored by the need for utmost transparency including a predetermined (ideally preregistered) study plan. Collaboration or counselling with an expert statistician is strongly encouraged.
    MeSH term(s) Bayes Theorem ; Football ; Humans ; Reproducibility of Results ; Sample Size ; Soccer
    Language English
    Publishing date 2021-09-14
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 2473-4446
    ISSN (online) 2473-4446
    DOI 10.1080/24733938.2021.1978106
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Improved Strength and Recovery After Velocity-Based Training: A Randomized Controlled Trial.

    Held, Steffen / Hecksteden, Anne / Meyer, Tim / Donath, Lars

    International journal of sports physiology and performance

    2021  Volume 16, Issue 8, Page(s) 1185–1193

    Abstract: Purpose: The present intervention study examined the effects of intensity-matched velocity-based strength training with a 10% velocity loss (VL10) versus traditional 1-repetition maximum (1RM) based resistance training to failure (TRF) on 1RM and ... ...

    Abstract Purpose: The present intervention study examined the effects of intensity-matched velocity-based strength training with a 10% velocity loss (VL10) versus traditional 1-repetition maximum (1RM) based resistance training to failure (TRF) on 1RM and maximal oxygen uptake (V˙O2max) in a concurrent training setting.
    Methods: Using the minimization method, 21 highly trained rowers (4 females and 17 males; 19.6 [2.1] y, 1.83 [0.07] m, 74.6 [8.8] kg, V˙O2max: 64.9 [8.5] mL·kg-1·min-1) were either assigned to VL10 or TRF. In addition to rowing endurance training (about 75 min·d-1), both groups performed strength training (5 exercises, 80% 1RM, 4 sets, 2-3 min interset recovery, 2 times/week) over 8 weeks. Squat, deadlift, bench row, and bench press 1RM and V˙O2max rowing-ergometer ramp tests were completed. Overall recovery and overall stress were monitored every evening using the Short Recovery and Stress Scale.
    Results: Large and significant group × time interactions (P < .03, ηp2>.23, standard mean differences [SMD] > 0.65) in favor of VL10 (averaged +18.0% [11.3%]) were observed for squat, bench row, and bench press 1RM compared with TRF (averaged +8.0% [2.9%]). V˙O2max revealed no interaction effects (P = .55, ηp2=.01, standard mean difference < .23) but large time effects (P < .05, ηp2>.27). Significant group × time interactions (P = .001, ηp2>.54, SMD > |0.525|) in favor of VL10 were also observed for overall recovery and overall stress 24 and 48 hours after strength training.
    Conclusions: VL10 serves as a promising means to improve strength capacity at lower repetitions and stress levels in highly trained athletes. Future research should investigate the interference effects of VL10 in strength endurance sports and its effects when increasing weekly VL10 sessions within one macrocycle.
    MeSH term(s) Endurance Training ; Ergometry ; Female ; Humans ; Male ; Posture ; Resistance Training/methods ; Water Sports
    Language English
    Publishing date 2021-02-04
    Publishing country United States
    Document type Journal Article ; Randomized Controlled Trial
    ISSN 1555-0273
    ISSN (online) 1555-0273
    DOI 10.1123/ijspp.2020-0451
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Does Higher Intensity Increase the Rate of Responders to Endurance Training When Total Energy Expenditure Remains Constant? A Randomized Controlled Trial.

    Reuter, Marcel / Rosenberger, Friederike / Barz, Andreas / Venhorst, Andreas / Blanz, Laura / Hecksteden, Anne / Meyer, Tim

    Sports medicine - open

    2023  Volume 9, Issue 1, Page(s) 35

    Abstract: Background: Standardized training prescriptions often result in large variation in training response with a substantial number of individuals that show little or no response at all. The present study examined whether the response in markers of ... ...

    Abstract Background: Standardized training prescriptions often result in large variation in training response with a substantial number of individuals that show little or no response at all. The present study examined whether the response in markers of cardiorespiratory fitness (CRF) to moderate intensity endurance training can be elevated by an increase in training intensity.
    Methods: Thirty-one healthy, untrained participants (46 ± 8 years, BMI 25.4 ± 3.3 kg m
    Results: There was a significant difference in [Formula: see text]O
    Conclusion: High-intensity interval training increases the rate of response in VO
    Language English
    Publishing date 2023-05-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2809942-4
    ISSN 2198-9761 ; 2199-1170
    ISSN (online) 2198-9761
    ISSN 2199-1170
    DOI 10.1186/s40798-023-00579-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Passive heat therapy: a promising preventive measure for people at risk of adverse health outcomes during heat extremes.

    Rodrigues, Patrick / Orssatto, Lucas B R / Gagnon, Daniel / Dahhak, Amine / Hecksteden, Anne / Stewart, Ian B / Minett, Geoffrey M

    Journal of applied physiology (Bethesda, Md. : 1985)

    2024  Volume 136, Issue 4, Page(s) 677–694

    Abstract: The world is experiencing increased frequency, duration, and severity of life-threatening heat extremes. Most hospitalizations and excess deaths during extreme heat events are associated with preexisting diseases in older adults. As climate change ... ...

    Abstract The world is experiencing increased frequency, duration, and severity of life-threatening heat extremes. Most hospitalizations and excess deaths during extreme heat events are associated with preexisting diseases in older adults. As climate change persists, the global population ages and the number of individuals with chronic diseases expands, more people are at risk of adverse health outcomes during extreme heat events. Therefore, proactive preventive measures are urgently needed to mitigate heat-related health risks within these populations. In this context, passive heat therapy (e.g., hot baths, saunas, and water-perfused suits) emerges as a promising countermeasure to improve physiological resilience to a warming planet. Passive heating improves cardiovascular function and overall health in older adults and individuals living with chronic diseases, offering the prospect of reducing cardiovascular strain during hotter days. Moreover, some studies suggest that passive heat therapy can be an effective strategy for heat acclimation (i.e., improved thermoregulation). This review describes the existing literature on the effects of passive heat therapy on cardiovascular and thermoregulatory responses in individuals with higher heat-related health risks and explores the use of passive heating as a strategy for heat acclimation to mitigate health risks during extreme heat events.
    MeSH term(s) Middle Aged ; Humans ; Aged ; Hot Temperature ; Body Temperature Regulation/physiology ; Cardiovascular System ; Chronic Disease ; Outcome Assessment, Health Care
    Language English
    Publishing date 2024-02-01
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 219139-8
    ISSN 1522-1601 ; 0021-8987 ; 0161-7567 ; 8750-7587
    ISSN (online) 1522-1601
    ISSN 0021-8987 ; 0161-7567 ; 8750-7587
    DOI 10.1152/japplphysiol.00701.2023
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Book ; Online ; Thesis: Individualisiertes Monitoring des Ermüdungszustandes mittels Kreatinkinase und Harnstoff im professionellen Badminton

    Barth, Vanessa [Verfasser] / Hecksteden, Anne [Akademischer Betreuer]

    2022  

    Author's details Vanessa Norina Barth ; Betreuer: Anne Hecksteden
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Saarländische Universitäts- und Landesbibliothek
    Publishing place Saarbrücken
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  8. Article ; Online: Poor Reliability of Measurement Instruments to Assess Acute Responses to Load in Soccer Players Irrespective of Biological Maturity Status.

    Ruf, Ludwig / Drust, Barry / Ehmann, Paul / Forster, Sabrina / Hecksteden, Anne / Meyer, Tim

    Pediatric exercise science

    2022  Volume 34, Issue 3, Page(s) 125–134

    Abstract: Purpose: To assess the short-term reliability of measurement instruments to quantify the acute psychophysiological response to load in adolescent soccer players in relation to biological maturity.: Methods: Data were collected from 108 U12 to U17 ... ...

    Abstract Purpose: To assess the short-term reliability of measurement instruments to quantify the acute psychophysiological response to load in adolescent soccer players in relation to biological maturity.
    Methods: Data were collected from 108 U12 to U17 soccer players on 2 consecutive weeks (pre, n = 32; at, n = 34; and post, n = 42 estimated peak height velocity). Measurements consisted of the Short Recovery and Stress Scale, a countermovement jump, assessment of leg stiffness, and a submaximal run to assess exercise heart rate and heart rate recovery. Test-retest reliability was assessed with the coefficient of variation (CV) and intraclass correlation coefficient (ICC).
    Results: Items of the Short Recovery and Stress Scale showed poor reliability across maturity groups (CV = 7.0%-53.5%; ICC = .28 to .79). Only few countermovement jump variables (jump height, concentric impulse, and concentric velocity) possessed good reliability. For most variables of the countermovement jump, reliability was better for the post peak height velocity group followed by at-peak height velocity and prepeak height velocity. Very high levels of reliability across maturity groups were observed for exercise heart rate (CV < 1.8%; ICC > .94), while heart rate recovery was more variable (CV < 16.5%; ICC > .48).
    Conclusion: Results suggest that the majority of investigated variables have poor reliability, questioning their ability to detect small, yet meaningful changes in acute responses to load in adolescent soccer players.
    MeSH term(s) Adolescent ; Athletic Performance ; Body Height ; Exercise ; Exercise Test ; Humans ; Reproducibility of Results ; Soccer
    Language English
    Publishing date 2022-01-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1042382-5
    ISSN 1543-2920 ; 0899-8493
    ISSN (online) 1543-2920
    ISSN 0899-8493
    DOI 10.1123/pes.2021-0070
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Dwarfs on the Shoulders of Giants: Bayesian Analysis With Informative Priors in Elite Sports Research and Decision Making.

    Hecksteden, Anne / Forster, Sabrina / Egger, Florian / Buder, Felix / Kellner, Ralf / Meyer, Tim

    Frontiers in sports and active living

    2022  Volume 4, Page(s) 793603

    Abstract: While sample sizes in elite sports are necessarily small, so are the effects that may be relevant. This conundrum is complicated by an understandable reluctance of athletes to comply with extensive study requirements. In Bayesian analyses, pre-existing ... ...

    Abstract While sample sizes in elite sports are necessarily small, so are the effects that may be relevant. This conundrum is complicated by an understandable reluctance of athletes to comply with extensive study requirements. In Bayesian analyses, pre-existing knowledge (e.g., from sub-elite trials) can be formally included to supplement scarce data. Moreover, some design specifics for small sample research extend to the extreme case of a single subject. This provides the basis for actionable feedback (e.g., about individual responses) thereby incentivising participation. As a proof-of-concept, we conducted a replicated cross-over trial on the effect of cold-water immersion (CWI) on sprint performance recovery in soccer players. Times for 30 m linear sprint and the initial 5 m section, respectively, were measured by light gates before and 24 h after induction of fatigue. Data were analysed by Bayesian and by standard frequentist methods. Informative priors are based on a published metaanalysis. Seven players completed the trial. Sprint performance was 4.156 ± 0.193 s for 30 m linear sprint and 0.978 ± 0.064 s for the initial 5 m section. CWI improved recovery of sprint time for the initial 5 m section (difference to control: -0.060 ± 0.060 s,
    Language English
    Publishing date 2022-03-17
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2624-9367
    ISSN (online) 2624-9367
    DOI 10.3389/fspor.2022.793603
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Endotoxin Tolerance Acquisition and Altered Hepatic Fatty Acid Profile in Aged Mice.

    Wiesenthal, Amanda A / Legroux, Thierry M / Richter, Chris / Junker, Björn H / Hecksteden, Anne / Kessler, Sonja M / Hoppstädter, Jessica / Kiemer, Alexandra K

    Biology

    2023  Volume 12, Issue 4

    Abstract: 1) Background: Aging is linked to an altered immune response and metabolism. Inflammatory conditions, such as sepsis, COVID-19, and steatohepatitis are more prevalent in the elderly and steatosis is linked both to severe COVID-19 and sepsis. We ... ...

    Abstract (1) Background: Aging is linked to an altered immune response and metabolism. Inflammatory conditions, such as sepsis, COVID-19, and steatohepatitis are more prevalent in the elderly and steatosis is linked both to severe COVID-19 and sepsis. We hypothesized that aging is linked to a loss of endotoxin tolerance, which normally protects the host from excessive inflammation, and that this is accompanied by elevated levels of hepatic lipids. (2) Methods: An in vivo lipopolysaccharide (LPS) tolerance model in young and old mice was used and the cytokine serum levels were measured by ELISA. Cytokine and toll-like receptor gene expression was determined by qPCR in the lungs and the liver; hepatic fatty acid composition was assessed by GC-MS. (3) Results: The old mice showed a distinct potential for endotoxin tolerance as suggested by the serum cytokine levels and gene expression in the lung tissue. Endotoxin tolerance was less pronounced in the livers of the aged mice. However, the fatty acid composition strongly differed in the liver tissues of the young and old mice with a distinct change in the ratio of C18 to C16 fatty acids. (4) Conclusions: Endotoxin tolerance is maintained in advanced age, but changes in the metabolic tissue homeostasis may lead to an altered immune response in old individuals.
    Language English
    Publishing date 2023-03-31
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2661517-4
    ISSN 2079-7737
    ISSN 2079-7737
    DOI 10.3390/biology12040530
    Database MEDical Literature Analysis and Retrieval System OnLINE

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