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  1. Book: Leben mit Kollagenosen und Vaskulitiden

    Witzke, Oliver / Moog, Philipp / Heemann, Uwe

    ein Ratgeber für Patienten ; [Fieber, Gelenkschmerzen, Hautausschläge, Hautverhärtungen, abgestorbene Finger, Nierenversagen, rote Augen, Lungenbluten, Nasenbluten, Asthma, Leistungsknick, Muskelschwäche, Thrombosen, Kopfschmerzen]

    2015  

    Author's details Oliver Witzke ; Philipp Moog ; Uwe Heemann
    Keywords Autoimmunerkrankungen ; Autoimmunkrankheiten ; Bindegewebserkrankungen ; Gefäßentzündungen ; Bindegewebskrankheit ; Vaskulitis ; Therapie
    Subject Medizinische Behandlung ; Behandlung ; Krankenbehandlung ; Gefäßentzündung ; Vasculitis ; Vascularitis ; Vaskulitiden ; Angiitis ; Systemische Vasculitis ; Vasculitides ; Angiitides ; Kollagenose ; Kollagenkrankheit ; Kollagenopathie ; Bindegewebserkrankung
    Language German
    Size XII, 162 S. : Ill., 185 mm x 125 mm, 270 g
    Edition 3. überarb. und erw. Aufl.
    Publisher Zuckschwerdt
    Publishing place München
    Publishing country Germany
    Document type Book
    HBZ-ID HT018603064
    ISBN 978-3-86371-152-8 ; 3-86371-152-1
    Database Catalogue ZB MED Medicine, Health

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  2. Book ; Thesis: Faktoren der chronischen Nierenabstoßung

    Heemann, Uwe

    1997  

    Author's details vorgelegt von Uwe Heemann
    Language German
    Size 87 Bl. : Ill., graph. Darst.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Essen, Univ., Habil.-Schr., 1997
    HBZ-ID HT008014812
    Database Catalogue ZB MED Medicine, Health

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  3. Book: Leben mit Kollagenosen und Vaskulitiden

    Witzke, Oliver / Heemann, Uwe

    ein Ratgeber für Patienten ; [Fieber, Gelenkschmerzen, Hautausschläge, Hautverhärtungen, abgestorbene Finger, Nierenversagen, rote Augen, Lungenbluten, Nasenbluten, Asthma, Leistungsknick, Muskelschwäche, Thrombosen, Kopfschmerzen]

    2010  

    Author's details Oliver Witzke und Uwe Heemann
    Keywords Bindegewebskrankheit ; Vaskulitis ; Therapie
    Subject Medizinische Behandlung ; Behandlung ; Krankenbehandlung ; Gefäßentzündung ; Vasculitis ; Vascularitis ; Vaskulitiden ; Angiitis ; Systemische Vasculitis ; Vasculitides ; Angiitides ; Kollagenose ; Kollagenkrankheit ; Kollagenopathie ; Bindegewebserkrankung
    Subject code 616.7706
    Language German
    Size XII, 156 S. : Ill., 19 cm, 270 gr.
    Edition 2., überarb. Aufl.
    Publisher Zuckschwerdt
    Publishing place München u.a.
    Publishing country Germany ; Austria ; United States
    Document type Book
    HBZ-ID HT016516027
    ISBN 978-3-88603-977-7 ; 3-88603-977-3
    Database Catalogue ZB MED Medicine, Health

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  4. Article ; Online: Is urine mRNA analysis a useful tool in the detection of acute rejection?

    Heemann, Uwe

    Expert review of clinical immunology

    2013  Volume 9, Issue 11, Page(s) 1011–1013

    Abstract: Suthanthiran et al. have correlated the mRNA of more than 4000 urine samples in a blinded fashion with the result of kidney biopsies after transplantation. This was the first study which used mRNA evaluation on a broad scale to investigate acute ... ...

    Abstract Suthanthiran et al. have correlated the mRNA of more than 4000 urine samples in a blinded fashion with the result of kidney biopsies after transplantation. This was the first study which used mRNA evaluation on a broad scale to investigate acute rejection. This study established an algorithm of different markers which was highly predictive for the outcome of the biopsy retrospectively. The study is highly relevant to the field, but as other studies needs to be validated in a prospective design testing whether the algorithm suggested indeed predicts the result of the biopsy. In the near future, a method such as used in this study could be applied to patients after transplantation as an early follow-up marker.
    MeSH term(s) Chemokine CXCL10/genetics ; Female ; Graft Rejection/diagnosis ; Humans ; Intracellular Signaling Peptides and Proteins/genetics ; Kidney Transplantation ; Male ; RNA, Messenger/urine ; RNA, Ribosomal/urine
    Chemical Substances Chemokine CXCL10 ; Intracellular Signaling Peptides and Proteins ; RNA, Messenger ; RNA, Ribosomal
    Language English
    Publishing date 2013-11
    Publishing country England
    Document type Comment ; Journal Article
    ZDB-ID 2274260-8
    ISSN 1744-8409 ; 1744-666X
    ISSN (online) 1744-8409
    ISSN 1744-666X
    DOI 10.1586/1744666X.2013.850417
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Intradialytic neuromuscular electrical stimulation with optional virtual reality distraction improves not only muscle strength and functional capacity but also serum albumin level in haemodialysis patients: a pilot randomized clinical trial.

    Schinner, Lena / Nagels, Klaus / Scherf, Julia / Schmaderer, Christoph / Heemann, Uwe / Küchle, Claudius / Hannemann, Liya

    BMC nephrology

    2023  Volume 24, Issue 1, Page(s) 246

    Abstract: Background: Sarcopenia is highly prevalent in haemodialysis (HD) patients and linked to a poor prognosis regarding comorbidities and premature mortality. Previous studies assessed the effects of neuromuscular electrical stimulation in haemodialysis ... ...

    Abstract Background: Sarcopenia is highly prevalent in haemodialysis (HD) patients and linked to a poor prognosis regarding comorbidities and premature mortality. Previous studies assessed the effects of neuromuscular electrical stimulation in haemodialysis patients. This study adds to the relevance of neuromuscular electrical stimulation (NMES) applications combined with a virtual reality (VR) distraction to increase intensity, dosage, and efficiency of NMES and slow sarcopenia progression in HD patients.
    Methods: We conducted a 12-week multicenter prospective randomised controlled trial. The patients were randomly assigned to one of the three groups: neuromuscular electrical stimulation with or without combined virtual reality distraction or control group.
    Results: The final analysis included 32 haemodialysis patients (mean age of 68 ± 10 years, 26 men). Interaction effects between groups and time (12 weeks) were significant regarding serum albumin levels (p = 0.008) and left quadriceps femoris muscle (QFM) force (p = 0.026). Both endpoints were increased in the NMES compared to the CO group at the end of the intervention. The NMES group increased serum albumin levels significantly after 12 weeks. The main effect of time was an increase in mean right QFM force between beginning and end of the intervention (p = 0.021). Functional capacity improved after 12 weeks in the NMES and NMES + VR but not in the control group, with a significant difference between the three groups (p = 0.022). Weight and body mass index increased in the NMES and NMES + VR groups, albeit not significantly. The effects of VR distraction on NMES efficiency were inconclusive.
    Conclusion: Intradialytic NMES increases serum albumin level, functional capacity, muscle strength in lower limb and in tendency weight and body mass index of HD patients. Effects on VR distraction are inconclusive. Large-scaled follow-up studies on integrated sports programs with NMES and active training in combination with VR as distraction and motivation accelerator are needed.
    Trial registration: German Clinical Trial Register: DRKS00029276 (Retrospectively registered: 30/06/2022).
    MeSH term(s) Male ; Humans ; Middle Aged ; Aged ; Sarcopenia ; Pilot Projects ; Prospective Studies ; Muscle Strength ; Electric Stimulation ; Serum Albumin
    Chemical Substances Serum Albumin
    Language English
    Publishing date 2023-08-23
    Publishing country England
    Document type Randomized Controlled Trial ; Multicenter Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2041348-8
    ISSN 1471-2369 ; 1471-2369
    ISSN (online) 1471-2369
    ISSN 1471-2369
    DOI 10.1186/s12882-023-03283-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Book ; Online ; Thesis: Bedeutung der "single-dose" Rituximab-Therapie in der Remissionsinduktion und Erhaltungstherapie bei ANCA-assozierter Vaskulitis

    Probst, Michael Egon Verfasser] / [Heemann, Uwe [Akademischer Betreuer] / Ibrahim, Tareq Gutachter] / [Heemann, Uwe [Gutachter]

    2022  

    Author's details Michael Egon Probst ; Gutachter: Tareq Ibrahim, Uwe Heemann ; Betreuer: Uwe Heemann
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Universitätsbibliothek der TU München
    Publishing place München
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  7. Article ; Online: The impact of regulatory T cells in acute rejection.

    Heemann, Uwe

    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association

    2012  Volume 27, Issue 6, Page(s) 2145–2146

    MeSH term(s) Antibodies, Monoclonal/therapeutic use ; Female ; Graft Rejection/immunology ; Humans ; Immunosuppressive Agents/therapeutic use ; Kidney Transplantation/immunology ; Male ; T-Lymphocytes, Regulatory/drug effects ; T-Lymphocytes, Regulatory/immunology
    Chemical Substances Antibodies, Monoclonal ; Immunosuppressive Agents
    Language English
    Publishing date 2012-06
    Publishing country England
    Document type Comment ; Editorial
    ZDB-ID 90594-x
    ISSN 1460-2385 ; 0931-0509
    ISSN (online) 1460-2385
    ISSN 0931-0509
    DOI 10.1093/ndt/gfs032
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Book ; Thesis: Regionale Analyse der Ursachen neonataler Letalität

    Heemann, Uwe

    1981 - 1983

    1986  

    Size 58 Bl. : graph. Darst.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Bochum, Univ., Diss., 1987
    HBZ-ID HT002891237
    Database Catalogue ZB MED Medicine, Health

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  9. Article: Fabry disease: what the cardiologist should consider in non-cardiac screening, diagnosis, and management-narrative review.

    Regenbogen, Claudia / Braunisch, Matthias Christoph / Schmaderer, Christoph / Heemann, Uwe

    Cardiovascular diagnosis and therapy

    2021  Volume 11, Issue 2, Page(s) 661–671

    Abstract: Fabry disease (FD) is a rare X chromosomally transmitted lysosomal storage disorders with an absence or deficiency of the enzyme alpha-galactosidase. The deposition of globotriaosylceramide (Gb3) may cause damage to all organs, particularly brain, heart ... ...

    Abstract Fabry disease (FD) is a rare X chromosomally transmitted lysosomal storage disorders with an absence or deficiency of the enzyme alpha-galactosidase. The deposition of globotriaosylceramide (Gb3) may cause damage to all organs, particularly brain, heart and kidney. While acroparaesthesia, hypo- or anhydrosis and diarrhoea are the main symptoms in childhood, cardiac involvement with left ventricular hypertrophy (LVH), renal insufficiency, diffuse pain attacks and apoplexy are the main symptoms in adulthood. Regular examinations are necessary to record organ involvement and its progression. A major challenge is therefore to make a diagnosis at an early disease stage. This is the only way that treatment can be started if there is an indication. If FD is suspected, alpha-galactosidase should be tested in male patients and genetic testing should be performed in females to confirm the diagnosis. Since 2001, enzyme replacement therapy (ERT) has been available as a causal therapy. In 2016, chaperone therapy with the drug Migalastat was approved in the European Union, which leads to stabilisation of the defective alpha-galactosidase. Studies on gene therapy to cure FD in phase I/II. This review summarizes which patient should be screened, how to confirm the diagnosis and which examinations should be performed in FD patients during the course of the disease.
    Language English
    Publishing date 2021-05-04
    Publishing country China (Republic : 1949- )
    Document type Journal Article ; Review
    ZDB-ID 2685043-6
    ISSN 2223-3660 ; 2223-3652
    ISSN (online) 2223-3660
    ISSN 2223-3652
    DOI 10.21037/cdt-20-845
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Book: Leben mit Kollagenosen und Vaskulitiden

    Witzke, Oliver / Heemann, Uwe

    ein Ratgeber für Patienten ; [Fieber, Gelenkschmerzen, Hautausschläge, Hautverhärtungen, abgestorbene Finger, Nierenversagen, rote Augen, Lungenbluten, Nasenbluten, Asthma, Leistungsknick, Muskelschwäche, Thrombosen, Kopfschmerzen]

    2007  

    Author's details Oliver Witzke und Uwe Heemann unter Mitarb. von Benjamin Wilde und Sebastian Dolff
    Keywords Bindegewebskrankheit ; Therapie ; Vaskulitis
    Subject Medizinische Behandlung ; Behandlung ; Krankenbehandlung ; Gefäßentzündung ; Vasculitis ; Vascularitis ; Vaskulitiden ; Angiitis ; Systemische Vasculitis ; Vasculitides ; Angiitides ; Kollagenose ; Kollagenkrankheit ; Kollagenopathie ; Bindegewebserkrankung
    Subject code 616.7706
    Language German
    Size XII, 156 S., Ill., 19 cm, 230 gr.
    Publisher Zuckschwerdt
    Publishing place München ; Wien ; New York
    Publishing country Germany ; Austria ; United States
    Document type Book
    HBZ-ID HT015439187
    ISBN 978-3-88603-911-1 ; 3-88603-911-0
    Database Catalogue ZB MED Medicine, Health

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