Article: Rapid Phenotypic Antibiotic Susceptibility Profiling of Clinical
Antibiotics (Basel, Switzerland)
2024 Volume 13, Issue 3
Abstract: Bloodstream infections (BSI) are defined by the presence of viable bacteria or fungi, accompanied by systemic signs of infection. Choosing empirical therapy based solely on patient risk factors and prior antibiotic susceptibility test (AST) may lead to ... ...
| Abstract | Bloodstream infections (BSI) are defined by the presence of viable bacteria or fungi, accompanied by systemic signs of infection. Choosing empirical therapy based solely on patient risk factors and prior antibiotic susceptibility test (AST) may lead to either ineffective treatment or unnecessarily broad-spectrum antibiotic exposure. In general, Clinical & Laboratory Standards Institute guideline-approved ASTs have a turnaround time of 48-72 h from sample to answer, a period that may result in a critical delay in the appropriate selection of therapy. Therefore, reducing the time required for AST is highly advantageous. We have previously shown that our novel rapid AST method, MAPt (Micro-Agar-PCR-test), accurately identifies susceptibility profiles for spiked bioterrorism agents like |
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| Language | English |
| Publishing date | 2024-02-29 |
| Publishing country | Switzerland |
| Document type | Journal Article |
| ZDB-ID | 2681345-2 |
| ISSN | 2079-6382 |
| ISSN | 2079-6382 |
| DOI | 10.3390/antibiotics13030231 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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