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  1. Book ; Thesis: The mpt operon of Mycobacterium avium subspecies paratuberculosis

    Heinzmann, Julia

    characterization and protective efficacy as recombinant antigen in mice

    2008  

    Author's details by Julia Heinzmann
    Language English
    Size 139 Bl., Ill., graph. Darst., 30 cm
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Hannover, Med. Hochsch., Diss., 2008
    HBZ-ID HT016111403
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2010 E 255 order for loan Magazin

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  2. Article ; Online: Paenibacillus helianthi sp. nov., a nitrogen fixing species isolated from the rhizosphere of Helianthus annuus L.

    Ambrosini, Adriana / Sant'Anna, Fernando Hayashi / Heinzmann, Júlia / de Carvalho Fernandes, Gabriela / Bach, Evelise / Passaglia, Luciane Maria Pereira

    Antonie van Leeuwenhoek

    2018  Volume 111, Issue 12, Page(s) 2463–2471

    Abstract: Three facultatively anaerobic endospore-forming bacteria were isolated from the rhizosphere of sunflowers grown in fields of Rio Grande do Sul State, Brazil. The designated type strain ... ...

    Abstract Three facultatively anaerobic endospore-forming bacteria were isolated from the rhizosphere of sunflowers grown in fields of Rio Grande do Sul State, Brazil. The designated type strain P26E
    MeSH term(s) Anaerobiosis/physiology ; Bacterial Typing Techniques ; Base Composition ; Brazil ; DNA, Bacterial/genetics ; Fatty Acids/biosynthesis ; Genotype ; Helianthus/microbiology ; Nitrogen/metabolism ; Nitrogen Fixation/physiology ; Paenibacillus/classification ; Paenibacillus/genetics ; Paenibacillus/isolation & purification ; Paenibacillus/metabolism ; Phenotype ; Phylogeny ; RNA, Ribosomal, 16S/genetics ; Rhizosphere ; Spores, Bacterial/physiology
    Chemical Substances DNA, Bacterial ; Fatty Acids ; RNA, Ribosomal, 16S ; Nitrogen (N762921K75)
    Language English
    Publishing date 2018-08-02
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 214861-4
    ISSN 1572-9699 ; 0003-6072
    ISSN (online) 1572-9699
    ISSN 0003-6072
    DOI 10.1007/s10482-018-1135-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Sportverletzungen an Hüfte und Becken

    Heinzmann, Julia / Pohlemann, Tim

    OP-JOURNAL - Wissenschaftliche, klinische und technische Informationen

    2008  Volume 24, Issue 2, Page(s) 84–94

    Abstract: Sportverletzungen an Hüfte, Becken und Leiste betreffen überwiegend die Weichteile wie Muskeln, Sehnen, Bänder und Schleimbeutel. Das Spektrum umfasst Prellungen, Zerrungen, Rupturen, Tendinitiden und Bursitiden. Darüber hinaus stellen Leistenschmerzen ... ...

    Abstract Sportverletzungen an Hüfte, Becken und Leiste betreffen überwiegend die Weichteile wie Muskeln, Sehnen, Bänder und Schleimbeutel. Das Spektrum umfasst Prellungen, Zerrungen, Rupturen, Tendinitiden und Bursitiden. Darüber hinaus stellen Leistenschmerzen ein häufiges Problem bei Sportlern dar. Aufgrund der Komplexizität der Anatomie von Hüfte, Becken und Leiste stellen die Weichteilverletzungen in diesem Bereich eines der schwierigsten Probleme in der Sportmedizin dar. Die Diagnosefindung erfordert neben einem umfassenden Wissen der differenzialdiagnostischen Möglichkeiten häufig eine interdisziplinäre Zusammenarbeit von Unfallchirurgen, Orthopäden, Allgemeinchirurgen, Gynäkologen und Neurologen. Frakturen treten in der Regel seltener auf. Meist handelt es sich dann um unkomplizierte Abriss- oder Stressfrakturen mit überwiegend konservativer Therapie. Schwere Frakturen von Becken, Hüfte und Azetabulum entstehen entweder durch Rasanztraumen bei Sportarten wie Skifahren, Motorsport und Reiten oder durch Sturz aus großer Höhe wie beim Fallschirmspringen, Bergsteigen etc. Die Behandlung dieser Frakturen richtet sich nach den Kriterien der Beckenchirurgie.
    Language German
    Document type Article
    ZDB-ID 1016068-1
    ISSN 1439-2496 ; 0178-1715
    ISSN 0178-1715
    DOI 10.1055/s-0028-1098002
    Database bibnet.org

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    Zs.A 2900: Show issues Location:
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  4. Conference proceedings: Multizenterstudie zur Erfassung der klinischen Langzeitergebnisse nach operativer Versorgung von Tibiakopfluxationsfrakturen vom Typ Moore V

    Weber, Axel / Heinzmann, Julia / Meyer, Christoph / Wirbel, Reiner

    2014  , Page(s) WI55–1363

    Event/congress Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU 2014); Berlin; ; Berufsverband der Fachärzte für Orthopädie; 2014
    Keywords Medizin, Gesundheit
    Publishing date 2014-10-13
    Publisher German Medical Science GMS Publishing House; Düsseldorf
    Document type Conference proceedings
    DOI 10.3205/14dkou397
    Database German Medical Science

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  5. Book ; Thesis: Die Buhllieder des Hans Sachs

    Heinzmann, Julia-Maria

    Form, Gehalt, Funktion und sozialhistorischer Ort

    (Gratia ; 38)

    2001  

    Author's details Julia-Maria Heinzmann
    Series title Gratia ; 38
    Keywords Liebeslied
    Language German
    Size 229 S, 24 cm
    Publisher Harrassowitz
    Publishing place Wiesbaden
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Univ., Diss.--Bamberg, 1999
    Note Literaturverz. S. [213] - 225
    ISBN 3447044314 ; 9783447044318
    Database Former special subject collection: coastal and deep sea fishing

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  6. Article ; Online: Gene-specific profiling of DNA methylation and mRNA expression in bovine oocytes derived from follicles of different size categories

    Mattern, F. / Heinzmann, Julia / Herrmann, Doris / Lucas-Hahn, Andrea / Haaf, T. / Niemann, Heiner

    2017  

    Abstract: Epigenetic changes, such as DNA methylation, play an essential role in the acquisition of full developmental competence by mammalian oocytes during the late follicular growth phase. Here we used the bovine model to investigate the DNA methylation ... ...

    Abstract Epigenetic changes, such as DNA methylation, play an essential role in the acquisition of full developmental competence by mammalian oocytes during the late follicular growth phase. Here we used the bovine model to investigate the DNA methylation profiles of seven candidate genes (imprinted: bH19, bSNRPN; non-imprinted: bZAR1, bDNMT3A, bOCT4, bDNMT3 Lo and bDNMT3 Ls) and the mRNA expression of nine candidate genes (imprinted: bSNRPN, bPEG3, bIGF2R; non-imprinted: bPRDX1, bDNMT1B, bDNMT3A, bZAR1, bHSF1 and bNLRP9) in oocytes from antral follicles of three different size classes (≤2 mm, 3–5 mm, ≥6 mm) to unravel the epigenetic contribution to this process. We observed an increased number of aberrantly methylated alleles in bH19, bSNRPN and bDNMT3 Lo of oocytes from small antral follicles (≤2 mm), correlating with lower developmental competence. Furthermore, we detected an increased frequency of CpG sites with an unclear methylation status for DNMT3 Ls, specifically in oocytes from follicles ≥6 mm, predominantly at three CpG positions (CpG2, CpG7 and CpG8), of which CpG7 is a potential regulatory site. No major differences in mRNA expression were observed, indicating that the transcriptional machinery may not yet be active during the follicular growth phase. Our results support the notion that a follicle diameter of ~2 mm is a critical stage for establishing DNA methylation profiles and indicate a link between DNA methylation and the acquisition of oocyte developmental competence.
    Keywords ddc:570 ; abnormally methylated alleles--CpG sites--epigenetics--imprinted genes--limited dilution assay--pyro-sequencing
    Subject code 570
    Language English
    Publishing date 2017-02-03
    Publishing country de
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Gene-specific profiling of DNA methylation and mRNA expression in bovine oocytes derived from follicles of different size categories

    Mattern, F. / Heinzmann, Julia / Herrmann, Doris / Lucas-Hahn, Andrea / Haaf, T. / Niemann, Heiner

    2017  

    Abstract: Epigenetic changes, such as DNA methylation, play an essential role in the acquisition of full developmental competence by mammalian oocytes during the late follicular growth phase. Here we used the bovine model to investigate the DNA methylation ... ...

    Abstract Epigenetic changes, such as DNA methylation, play an essential role in the acquisition of full developmental competence by mammalian oocytes during the late follicular growth phase. Here we used the bovine model to investigate the DNA methylation profiles of seven candidate genes (imprinted: bH19, bSNRPN; non-imprinted: bZAR1, bDNMT3A, bOCT4, bDNMT3 Lo and bDNMT3 Ls) and the mRNA expression of nine candidate genes (imprinted: bSNRPN, bPEG3, bIGF2R; non-imprinted: bPRDX1, bDNMT1B, bDNMT3A, bZAR1, bHSF1 and bNLRP9) in oocytes from antral follicles of three different size classes (≤2 mm, 3–5 mm, ≥6 mm) to unravel the epigenetic contribution to this process. We observed an increased number of aberrantly methylated alleles in bH19, bSNRPN and bDNMT3 Lo of oocytes from small antral follicles (≤2 mm), correlating with lower developmental competence. Furthermore, we detected an increased frequency of CpG sites with an unclear methylation status for DNMT3 Ls, specifically in oocytes from follicles ≥6 mm, predominantly at three CpG positions (CpG2, CpG7 and CpG8), of which CpG7 is a potential regulatory site. No major differences in mRNA expression were observed, indicating that the transcriptional machinery may not yet be active during the follicular growth phase. Our results support the notion that a follicle diameter of ~2 mm is a critical stage for establishing DNA methylation profiles and indicate a link between DNA methylation and the acquisition of oocyte developmental competence.
    Keywords Text ; ddc:570 ; abnormally methylated alleles -- CpG sites -- epigenetics -- imprinted genes -- limited dilution assay -- pyro-sequencing
    Subject code 570
    Language English
    Publishing date 2017-02-03
    Publishing country de
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: DNA methylation and mRNA expression of developmentally important genes in bovine oocytes collected from donors of different age categories.

    Mattern, Felix / Herrmann, Doris / Heinzmann, Julia / Hadeler, Klaus Gerd / Bernal-Ulloa, Sandra Milena / Haaf, Thomas / Niemann, Heiner

    Molecular reproduction and development

    2016  Volume 83, Issue 9, Page(s) 802–814

    Abstract: Epigenetic changes are critical for the acquisition of developmental potential by oocytes and embryos, yet these changes may be sensitive to maternal ageing. Here, we investigated the impact of maternal ageing on DNA methylation and mRNA expression in a ... ...

    Abstract Epigenetic changes are critical for the acquisition of developmental potential by oocytes and embryos, yet these changes may be sensitive to maternal ageing. Here, we investigated the impact of maternal ageing on DNA methylation and mRNA expression in a panel of eight genes that are critically involved in oocyte and embryo development. Bovine oocytes were collected from donors of three different age categories-prepubertal (9-12 months old), mature (3-7 years old), and aged (8-11 years old)-and were analyzed for gene-specific DNA methylation (bTERF2, bREC8, bBCL-XL, bPISD, bBUB1, bDNMT3Lo, bH19, and bSNRPN) and mRNA expression (bTERF2, bBCL-XL, bPISD, and bBUB1). A total of 1,044 alleles with 88,740 CpGs were amplified and sequenced from 362 bovine oocytes. Most of the detected molecules were either fully methylated or completely unmethylated. Only 9 out of 1,044 alleles (<1%) were abnormally methylated (>50% of CpGs with an aberrant methylation status), and seven of the nine abnormally methylated alleles were within only two candidate genes (bDNMT3Lo and bH19). No significant differences were detected with regard to mRNA expression between oocytes from the three groups of donors. These results suggest that genes predominantly important for early embryo development (bH19 and bDNMT3Lo) are less resistant to abnormal methylation than genes critically involved in oocyte development (bTERF2, bBCL-XL, bPISD, bBUB1, and bSNRPN). Establishment of DNA methylation in bovine oocytes seems to be largely resistant to changes caused by maternal ageing, irrespective of whether the genes are critical to achieve developmental competence in oocytes or early embryos. Mol. Reprod. Dev. 83: 802-814, 2016 © 2016 Wiley Periodicals, Inc.
    Language English
    Publishing date 2016-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 20321-x
    ISSN 1098-2795 ; 1040-452X
    ISSN (online) 1098-2795
    ISSN 1040-452X
    DOI 10.1002/mrd.22692
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2759: Show issues Location:
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  9. Article: Sportverletzungen an Hüfte und Becken

    Heinzmann, Julia / Pohlemann, Tim

    OP-JOURNAL

    2008  Volume 24, Issue 02, Page(s) 84–94

    Abstract: Sportverletzungen an Hüfte, Becken und Leiste betreffen überwiegend die Weichteile wie Muskeln, Sehnen, Bänder und Schleimbeutel. Das Spektrum umfasst Prellungen, Zerrungen, Rupturen, Tendinitiden und Bursitiden. Darüber hinaus stellen Leistenschmerzen ... ...

    Abstract Sportverletzungen an Hüfte, Becken und Leiste betreffen überwiegend die Weichteile wie Muskeln, Sehnen, Bänder und Schleimbeutel. Das Spektrum umfasst Prellungen, Zerrungen, Rupturen, Tendinitiden und Bursitiden. Darüber hinaus stellen Leistenschmerzen ein häufiges Problem bei Sportlern dar. Aufgrund der Komplexizität der Anatomie von Hüfte, Becken und Leiste stellen die Weichteilverletzungen in diesem Bereich eines der schwierigsten Probleme in der Sportmedizin dar. Die Diagnosefindung erfordert neben einem umfassenden Wissen der differenzialdiagnostischen Möglichkeiten häufig eine interdisziplinäre Zusammenarbeit von Unfallchirurgen, Orthopäden, Allgemeinchirurgen, Gynäkologen und Neurologen. Frakturen treten in der Regel seltener auf. Meist handelt es sich dann um unkomplizierte Abriss– oder Stressfrakturen mit überwiegend konservativer Therapie. Schwere Frakturen von Becken, Hüfte und Azetabulum entstehen entweder durch Rasanztraumen bei Sportarten wie Skifahren, Motorsport und Reiten oder durch Sturz aus großer Höhe wie beim Fallschirmspringen, Bergsteigen etc. Die Behandlung dieser Frakturen richtet sich nach den Kriterien der Beckenchirurgie.
    Language German
    Publishing date 2008-10-01
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2375266-X
    ISSN 1439-2496 ; 0178-1715
    ISSN (online) 1439-2496
    ISSN 0178-1715
    DOI 10.1055/s-0028-1098002
    Database Thieme publisher's database

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  10. Book ; Audio / Video ; Online: Postovulatory ageing influences methylation marks and development in bovine oocytes and early embryos

    Heinzmann, Julia* / Heinzmann, Julia / Mattern, F. / Aldag, Patrick / Lucas-Hahn, Andrea / Wrenzycki, C. / Haaf, T. / Niemann, Heiner

    2014  

    Language English
    Publishing country de
    Document type Book ; Audio / Video ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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