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  1. Article: Interrater reliability of the Fugl-Meyer Motor assessment in stroke patients: a quality management project within the ESTREL study.

    Wiesner, Karin / Schwarz, Anne / Meya, Louisa / Kaufmann, Josefin Emelie / Traenka, Christopher / Luft, Andreas Rüdiger / Held, Jeremia Philipp Oskar / Engelter, Stefan

    Frontiers in neurology

    2024  Volume 15, Page(s) 1335375

    Abstract: Introduction: The Fugl-Meyer Motor Assessment (FMMA) is recommended for evaluating stroke motor recovery in clinical practice and research. However, its widespread use requires refined reliability data, particularly across different health professions. ... ...

    Abstract Introduction: The Fugl-Meyer Motor Assessment (FMMA) is recommended for evaluating stroke motor recovery in clinical practice and research. However, its widespread use requires refined reliability data, particularly across different health professions. We therefore investigated the interrater reliability of the FMMA scored by a physical therapist and a physician using video recordings of stroke patients.
    Methods: The FMMA videos of 50 individuals 3 months post stroke (28 females, mean age 71.64 years, median National Institutes of Health Stroke Scale score 3.00) participating in the ESTREL trial (Enhancement of Stroke Rehabilitation with Levodopa: a randomized placebo-controlled trial) were independently scored by two experienced assessors (i.e., a physical therapist and a physician) with specific training to ensure consistency. As primary endpoint, the interrater reliability was calculated for the total scores of the entire FMMA and the total scores of the FMMA for the upper and lower extremities using intraclass correlation coefficients (ICC). In addition, Spearman's rank order correlation coefficients (Spearman's rho) were calculated for the total score and subscale levels. Secondary endpoints included the FMMA item scores using percentage agreement, weighted Cohen's kappa coefficients, and Gwet's AC1/AC2 coefficients.
    Results: ICCs were 0.98 (95% confidence intervals (CI) 0.96-0.99) for the total scores of the entire FMMA, 0.98 (95% CI 0.96-0.99) for the total scores of the FMMA for the upper extremity, and 0.85 (95% CI 0.70-0.92) for the total scores of the FMMA for the lower extremity. Spearman's rho ranged from 0.61 to 0.94 for total and subscale scores. The interrater reliability at the item level of the FMMA showed (i) percentage agreement values with a median of 77% (range 44-100%), (ii) weighted Cohen's kappa coefficients with a median of 0.69 (range 0.00-0.98) and (iii) Gwet's AC1/AC2 coefficients with a median of 0.84 (range 0.42-0.98).
    Discussion and conclusion: The FMMA appears to be a highly reliable measuring instrument at the overall score level for assessors from different health professions. The FMMA total scores seem to be suitable for the quantitative measurement of stroke recovery in both clinical practice and research, although there is potential for improvement at the item level.
    Language English
    Publishing date 2024-04-08
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2564214-5
    ISSN 1664-2295
    ISSN 1664-2295
    DOI 10.3389/fneur.2024.1335375
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Augmented Reality-Based Rehabilitation of Gait Impairments: Case Report.

    Held, Jeremia Philipp Oskar / Yu, Kevin / Pyles, Connor / Veerbeek, Janne Marieke / Bork, Felix / Heining, Sandro-Michael / Navab, Nassir / Luft, Andreas Rüdiger

    JMIR mHealth and uHealth

    2020  Volume 8, Issue 5, Page(s) e17804

    Abstract: Background: Gait and balance impairments are common in neurological diseases, including stroke, and negatively affect patients' quality of life. Improving balance and gait are among the main goals of rehabilitation. Rehabilitation is mainly performed in ...

    Abstract Background: Gait and balance impairments are common in neurological diseases, including stroke, and negatively affect patients' quality of life. Improving balance and gait are among the main goals of rehabilitation. Rehabilitation is mainly performed in clinics, which lack context specificity; therefore, training in the patient's home environment is preferable. In the last decade, developed rehabilitation technologies such as virtual reality and augmented reality (AR) have enabled gait and balance training outside clinics. Here, we propose a new method for gait rehabilitation in persons who have had a stroke in which mobile AR technology and a sensor-based motion capture system are combined to provide fine-grained feedback on gait performance in real time.
    Objective: The aims of this study were (1) to investigate manipulation of the gait pattern of persons who have had a stroke based on virtual augmentation during overground walking compared to walking without AR performance feedback and (2) to investigate the usability of the AR system.
    Methods: We developed the ARISE (Augmented Reality for gait Impairments after StrokE) system, in which we combined a development version of HoloLens 2 smart glasses (Microsoft Corporation) with a sensor-based motion capture system. One patient with chronic minor gait impairment poststroke completed clinical gait assessments and an AR parkour course with patient-centered performance gait feedback. The movement kinematics during gait as well as the usability and safety of the system were evaluated.
    Results: The patient changed his gait pattern during AR parkour compared to the pattern observed during the clinical gait assessments. He recognized the virtual objects and ranked the usability of the ARISE system as excellent. In addition, the patient stated that the system would complement his standard gait therapy. Except for the symptom of exhilaration, no adverse events occurred.
    Conclusions: This project provided the first evidence of gait adaptation during overground walking based on real-time feedback through visual and auditory augmentation. The system has potential to provide gait and balance rehabilitation outside the clinic. This initial investigation of AR rehabilitation may aid the development and investigation of new gait and balance therapies.
    MeSH term(s) Augmented Reality ; Gait ; Humans ; Male ; Quality of Life ; Stroke Rehabilitation ; Walking
    Language English
    Publishing date 2020-05-26
    Publishing country Canada
    Document type Case Reports ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2719220-9
    ISSN 2291-5222 ; 2291-5222
    ISSN (online) 2291-5222
    ISSN 2291-5222
    DOI 10.2196/17804
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Corrigendum: Consensus-Based Core Set of Outcome Measures for Clinical Motor Rehabilitation After Stroke-A Delphi Study.

    Pohl, Johannes / Held, Jeremia Philipp Oskar / Verheyden, Geert / Alt Murphy, Margit / Engelter, Stefan / Flöel, Agnes / Keller, Thierry / Kwakkel, Gert / Nef, Tobias / Ward, Nick / Luft, Andreas Rüdiger / Veerbeek, Janne Marieke

    Frontiers in neurology

    2021  Volume 12, Page(s) 697935

    Abstract: This corrects the article DOI: 10.3389/fneur.2020.00875.]. ...

    Abstract [This corrects the article DOI: 10.3389/fneur.2020.00875.].
    Language English
    Publishing date 2021-05-27
    Publishing country Switzerland
    Document type Published Erratum
    ZDB-ID 2564214-5
    ISSN 1664-2295
    ISSN 1664-2295
    DOI 10.3389/fneur.2021.697935
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Economic Impact of Poststroke Delirium and Associated Risk Factors: Findings From a Prospective Cohort Study.

    Zipser, Carl Moritz / Deuel, Jeremy Werner / Held, Jeremia Philipp Oskar / Ernst, Jutta / Schubert, Maria / Weller, Michael / Luft, Andreas Rüdiger / von Känel, Roland / Boettger, Soenke

    Stroke

    2021  Volume 52, Issue 10, Page(s) 3325–3334

    Abstract: Background and purpose: Delirium is a common severe complication of stroke. We aimed to determine the cost-of-illness and risk factors of poststroke delirium (PSD).: Methods: This prospective single-center study included n=567 patients with acute ... ...

    Abstract Background and purpose: Delirium is a common severe complication of stroke. We aimed to determine the cost-of-illness and risk factors of poststroke delirium (PSD).
    Methods: This prospective single-center study included n=567 patients with acute stroke from a hospital-wide delirium cohort study and the Swiss Stroke Registry in 2014. Delirium was determined by Delirium Observation Screening Scale or Intensive Care Delirium Screening Checklist 3 times daily during the first 3 days of admission. Costs reflected the case-mix index and diagnosis-related groups from 2014 and were divided into nursing, physician, and total costs. Factors associated with PSD were assessed with multiple regression analysis. Partial correlations and quantile regression were performed to assess costs and other factors associated with PSD.
    Results: The incidence of PSD was 39.0% (221/567). Patients with delirium were older than non-PSD (median 76 versus 70 years; P<0.001), 52% male (115/221) versus 62% non-PSD (214/346) and hospitalized longer (mean 11.5 versus 9.3 days; P<0.001). Dementia was the most relevant predisposing factor for PSD (odds ratio, 16.02 [2.83–90.69], P=0.002). Moderate to severe stroke (National Institutes of Health Stroke Scale score 16–20) was the most relevant precipitating factor (odds ratio, 36.10 [8.15–159.79], P<0.001). PSD was a strong predictor for 3-month mortality (odds ratio, 15.11 [3.33–68.53], P<0.001). Nursing and total costs were nearly twice as high in PSD (P<0.001). There was a positive correlation between total costs and admission National Institutes of Health Stroke Scale (correlation coefficient, 0.491; P<0.001) and length of stay (correlation coefficient, 0.787; P<0.001) in all patients. Quantile regression revealed rising nursing and total costs associated with PSD, higher National Institutes of Health Stroke Scale, and longer hospital stay (all P<0.05).
    Conclusions: PSD was associated with greater stroke severity, prolonged hospitalization, and increased nursing and total costs. In patients with severe stroke, dementia, or seizures, PSD is anticipated, and additional costs are associated with hospitalization.
    MeSH term(s) Aged ; Aged, 80 and over ; Cohort Studies ; Cost of Illness ; Delirium/economics ; Delirium/etiology ; Economics, Nursing ; Female ; Humans ; Incidence ; Length of Stay ; Male ; Middle Aged ; Prognosis ; Prospective Studies ; Risk Factors ; Seizures/economics ; Seizures/etiology ; Stroke/complications ; Stroke/economics ; Stroke/mortality ; Switzerland
    Language English
    Publishing date 2021-07-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80381-9
    ISSN 1524-4628 ; 0039-2499 ; 0749-7954
    ISSN (online) 1524-4628
    ISSN 0039-2499 ; 0749-7954
    DOI 10.1161/STROKEAHA.120.033005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Augmented Reality–Based Rehabilitation of Gait Impairments

    Held, Jeremia Philipp Oskar / Yu, Kevin / Pyles, Connor / Veerbeek, Janne Marieke / Bork, Felix / Heining, Sandro-Michael / Navab, Nassir / Luft, Andreas Rüdiger

    JMIR mHealth and uHealth, Vol 8, Iss 5, p e

    Case Report

    2020  Volume 17804

    Abstract: BackgroundGait and balance impairments are common in neurological diseases, including stroke, and negatively affect patients’ quality of life. Improving balance and gait are among the main goals of rehabilitation. Rehabilitation is mainly performed in ... ...

    Abstract BackgroundGait and balance impairments are common in neurological diseases, including stroke, and negatively affect patients’ quality of life. Improving balance and gait are among the main goals of rehabilitation. Rehabilitation is mainly performed in clinics, which lack context specificity; therefore, training in the patient’s home environment is preferable. In the last decade, developed rehabilitation technologies such as virtual reality and augmented reality (AR) have enabled gait and balance training outside clinics. Here, we propose a new method for gait rehabilitation in persons who have had a stroke in which mobile AR technology and a sensor-based motion capture system are combined to provide fine-grained feedback on gait performance in real time. ObjectiveThe aims of this study were (1) to investigate manipulation of the gait pattern of persons who have had a stroke based on virtual augmentation during overground walking compared to walking without AR performance feedback and (2) to investigate the usability of the AR system. MethodsWe developed the ARISE (Augmented Reality for gait Impairments after StrokE) system, in which we combined a development version of HoloLens 2 smart glasses (Microsoft Corporation) with a sensor-based motion capture system. One patient with chronic minor gait impairment poststroke completed clinical gait assessments and an AR parkour course with patient-centered performance gait feedback. The movement kinematics during gait as well as the usability and safety of the system were evaluated. ResultsThe patient changed his gait pattern during AR parkour compared to the pattern observed during the clinical gait assessments. He recognized the virtual objects and ranked the usability of the ARISE system as excellent. In addition, the patient stated that the system would complement his standard gait therapy. Except for the symptom of exhilaration, no adverse events occurred. ConclusionsThis project provided the first evidence of gait adaptation during overground walking based on ...
    Keywords Information technology ; T58.5-58.64 ; Public aspects of medicine ; RA1-1270
    Subject code 629
    Language English
    Publishing date 2020-05-01T00:00:00Z
    Publisher JMIR Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article: Consensus-Based Core Set of Outcome Measures for Clinical Motor Rehabilitation After Stroke-A Delphi Study.

    Pohl, Johannes / Held, Jeremia Philipp Oskar / Verheyden, Geert / Alt Murphy, Margit / Engelter, Stefan / Flöel, Agnes / Keller, Thierry / Kwakkel, Gert / Nef, Tobias / Ward, Nick / Luft, Andreas Rüdiger / Veerbeek, Janne Marieke

    Frontiers in neurology

    2020  Volume 11, Page(s) 875

    Abstract: Introduction: ...

    Abstract Introduction:
    Language English
    Publishing date 2020-09-02
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2564214-5
    ISSN 1664-2295
    ISSN 1664-2295
    DOI 10.3389/fneur.2020.00875
    Database MEDical Literature Analysis and Retrieval System OnLINE

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