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  1. Article ; Online: Not All Tumor-Infiltrating CD8

    Held, Werner / Speiser, Daniel E

    Cancer cell

    2021  Volume 39, Issue 2, Page(s) 145–147

    Abstract: Adoptive cell immunotherapy using in vitro expanded autologous tumor-infiltrating lymphocytes has the potential to mediate durable remission of certain types of cancer. A recent paper in Science shows that complete and durable control of metastatic ... ...

    Abstract Adoptive cell immunotherapy using in vitro expanded autologous tumor-infiltrating lymphocytes has the potential to mediate durable remission of certain types of cancer. A recent paper in Science shows that complete and durable control of metastatic melanoma requires the infusion of tumor-specific CD8
    Language English
    Publishing date 2021-02-09
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 2078448-X
    ISSN 1878-3686 ; 1535-6108
    ISSN (online) 1878-3686
    ISSN 1535-6108
    DOI 10.1016/j.ccell.2021.01.015
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Stem-cell-like T cells have a specific entry gate to the tumor.

    Held, Werner / Luther, Sanjiv A / Petrova, Tatiana V

    Cancer cell

    2022  Volume 40, Issue 3, Page(s) 243–245

    Abstract: Tumor-infiltrated T cells with stem-cell-like properties are important for determining the immunotherapy response. In this issue of Cancer Cell, Asrir and colleagues show that their entry requires specialized tumor-associated endothelial cells that ... ...

    Abstract Tumor-infiltrated T cells with stem-cell-like properties are important for determining the immunotherapy response. In this issue of Cancer Cell, Asrir and colleagues show that their entry requires specialized tumor-associated endothelial cells that resemble immature and inflamed lymph node vessels and that immunotherapy enhances the recruitment capacity of these endothelial cells.
    MeSH term(s) CTLA-4 Antigen ; Endothelial Cells ; Humans ; Immunotherapy ; Lymph Nodes/pathology ; Lymphocytes ; Neoplasms/pathology ; Neoplasms/therapy ; Programmed Cell Death 1 Receptor ; T-Lymphocytes/pathology ; Venules/pathology
    Chemical Substances CTLA-4 Antigen ; Programmed Cell Death 1 Receptor
    Language English
    Publishing date 2022-02-16
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 2078448-X
    ISSN 1878-3686 ; 1535-6108
    ISSN (online) 1878-3686
    ISSN 1535-6108
    DOI 10.1016/j.ccell.2022.02.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: PD-1

    Charmoy, Mélanie / Wyss, Tania / Delorenzi, Mauro / Held, Werner

    Cell reports

    2021  Volume 37, Issue 6, Page(s) 110010

    Language English
    Publishing date 2021-11-24
    Publishing country United States
    Document type Published Erratum
    ZDB-ID 2649101-1
    ISSN 2211-1247 ; 2211-1247
    ISSN (online) 2211-1247
    ISSN 2211-1247
    DOI 10.1016/j.celrep.2021.110010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Inhibitory receptors and their mode of action: key insights from NK cells.

    Held, Werner

    Journal of immunology (Baltimore, Md. : 1950)

    2013  Volume 191, Issue 7, Page(s) 3489–3490

    MeSH term(s) Cytotoxicity, Immunologic ; HLA-C Antigens/metabolism ; Humans ; Killer Cells, Natural/immunology ; Protein Tyrosine Phosphatases/immunology ; Receptors, Cytoplasmic and Nuclear/immunology ; Receptors, Immunologic/immunology ; Receptors, KIR/immunology
    Chemical Substances HLA-C Antigens ; Receptors, Cytoplasmic and Nuclear ; Receptors, Immunologic ; Receptors, KIR ; Protein Tyrosine Phosphatases (EC 3.1.3.48)
    Language English
    Publishing date 2013-10-01
    Publishing country United States
    Document type Comment ; Journal Article
    ZDB-ID 3056-9
    ISSN 1550-6606 ; 0022-1767 ; 1048-3233 ; 1047-7381
    ISSN (online) 1550-6606
    ISSN 0022-1767 ; 1048-3233 ; 1047-7381
    DOI 10.4049/jimmunol.1302158
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: PD-1

    Charmoy, Mélanie / Wyss, Tania / Delorenzi, Mauro / Held, Werner

    Cell reports

    2021  Volume 36, Issue 10, Page(s) 109672

    Abstract: Virus-specific ... ...

    Abstract Virus-specific PD1
    MeSH term(s) Animals ; CD8-Positive T-Lymphocytes/immunology ; Gene Expression Profiling/methods ; Immunologic Memory/immunology ; Lymphocytic Choriomeningitis/immunology ; Lymphocytic Choriomeningitis/virology ; Lymphocytic choriomeningitis virus/immunology ; Lymphocytic choriomeningitis virus/pathogenicity ; Mice, Inbred C57BL ; Persistent Infection/immunology ; Persistent Infection/virology ; T Cell Transcription Factor 1/immunology ; Mice
    Chemical Substances T Cell Transcription Factor 1 ; TCF7 protein, human
    Language English
    Publishing date 2021-09-08
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2649101-1
    ISSN 2211-1247 ; 2211-1247
    ISSN (online) 2211-1247
    ISSN 2211-1247
    DOI 10.1016/j.celrep.2021.109672
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Hugh Robson MacDonald (1946-2023).

    Wilson, Anne / Ferrero, Isabel / Speiser, Daniel E / Held, Werner / Romero, Pedro

    Immunity

    2023  Volume 56, Issue 5, Page(s) 893–894

    Language English
    Publishing date 2023-05-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1217235-2
    ISSN 1097-4180 ; 1074-7613
    ISSN (online) 1097-4180
    ISSN 1074-7613
    DOI 10.1016/j.immuni.2023.04.018
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Nonclassical NK cell education.

    Held, Werner

    Nature immunology

    2012  Volume 13, Issue 12, Page(s) 1135–1137

    MeSH term(s) Animals ; Histocompatibility Antigens Class I/immunology ; Histocompatibility Antigens Class I/metabolism ; Killer Cells, Natural/immunology ; Lymphocyte Activation ; NK Cell Lectin-Like Receptor Subfamily A/metabolism
    Chemical Substances H2-M3 antigen ; Histocompatibility Antigens Class I ; Klra1 protein, mouse ; NK Cell Lectin-Like Receptor Subfamily A
    Language English
    Publishing date 2012-11-19
    Publishing country United States
    Document type News ; Comment
    ZDB-ID 2016987-5
    ISSN 1529-2916 ; 1529-2908
    ISSN (online) 1529-2916
    ISSN 1529-2908
    DOI 10.1038/ni.2470
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Book ; Thesis: Neurologische Komplikationen nach Herzoperationen bei Kindern

    Held, Werner

    1985  

    Size 155 S. : graph. Darst.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Erlangen, Nürnberg, Univ., Diss., 1985
    HBZ-ID HT003077453
    Database Catalogue ZB MED Medicine, Health

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  9. Article ; Online: A KIR-TLR connection.

    Held, Werner

    Blood

    2010  Volume 116, Issue 10, Page(s) 1629–1630

    Language English
    Publishing date 2010-09-09
    Publishing country United States
    Document type Comment ; Journal Article
    ZDB-ID 80069-7
    ISSN 1528-0020 ; 0006-4971
    ISSN (online) 1528-0020
    ISSN 0006-4971
    DOI 10.1182/blood-2010-03-272203
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Emergence and fate of stem cell-like

    Silva, Joana Gomes / Pais Ferreira, Daniela / Dumez, Alexandre / Wyss, Tania / Veber, Romain / Danilo, Maxime / Pinschewer, Daniel D / Charmoy, Mélanie / Held, Werner

    Science immunology

    2023  Volume 8, Issue 89, Page(s) eadh3113

    Abstract: In response to infection, naïve ... ...

    Abstract In response to infection, naïve CD8
    MeSH term(s) Humans ; CD8-Positive T-Lymphocytes ; Virus Diseases ; Stem Cells ; Inflammation/metabolism ; Immunity
    Language English
    Publishing date 2023-11-17
    Publishing country United States
    Document type Journal Article
    ISSN 2470-9468
    ISSN (online) 2470-9468
    DOI 10.1126/sciimmunol.adh3113
    Database MEDical Literature Analysis and Retrieval System OnLINE

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