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  1. Article ; Online: Cuisine in transition? Organic residue analysis of domestic containers from 9th-14th century Sicily

    Jasmine Lundy / Lea Drieu / Paola Orecchioni / Antonino Meo / Veronica Aniceti / Girolamo Fiorentino / Milena Primavera / Helen Talbot / Alessandra Molinari / Martin O. H. Carver / Oliver E. Craig

    Royal Society Open Science, Vol 10, Iss

    2023  Volume 3

    Abstract: From the 9th to 14th centuries AD, Sicily experienced a series of rapid and quite radical changes in political regime, but the impact of these regime changes on the lives of the people that experienced them remains largely elusive within the historical ... ...

    Abstract From the 9th to 14th centuries AD, Sicily experienced a series of rapid and quite radical changes in political regime, but the impact of these regime changes on the lives of the people that experienced them remains largely elusive within the historical narrative. We use a multi-faceted lipid residue approach to give direct chemical evidence of the use of 248 everyday domestic ceramic containers from Islamic and post-Islamic contexts in western Sicily to aid our understanding of daily habits throughout this period of political change. A range of commodities was successfully identified, including animal fats, vegetable products, fruit products (potentially including wine) and plant resins. The study highlights the complexity of residues in early medieval Mediterranean society as, in many cases, mixtures of commodities were observed reflecting sequential cooking events and/or the complex mixtures reflective of medieval recipes. However, overall, there were no clear changes in the composition of the residues following the imposition of Norman control over the island and through subsequent periods, despite some differences between urban centres and rural sites. Thus, lending to the idea that post-Islamic populations largely flourished and benefited from the agricultural systems, resources and recipes left by their predecessors.
    Keywords archaeology ; medieval Sicily ; organic residue analysis ; cuisine ; ceramics ; Science ; Q
    Subject code 930
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher The Royal Society
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: A mixed-methods feasibility and external pilot study to inform a large pragmatic randomised controlled trial of the effects of surgical wound dressing strategies on surgical site infections (Bluebelle Phase B)

    The Bluebelle Study Group / Barnaby C. Reeves / Lazaros Andronis / Jane M. Blazeby / Natalie S. Blencowe / Melanie Calvert / Joanna Coast / Tim Draycott / Jenny L. Donovan / Rachael Gooberman-Hill / Robert J. Longman / Laura Magill / Jonathan M. Mathers / Thomas D. Pinkney / Chris A. Rogers / Leila Rooshenas / Andrew Torrance / Nicky J. Welton / Mark Woodward /
    Kate Ashton / Katarzyna D. Bera / Gemma L. Clayton / Lucy A. Culliford / Jo C. Dumville / Daisy Elliott / Lucy Ellis / Hannah Gould-Brown / Rhiannon C. Macefield / Christel McMullan / Caroline Pope / Dimitrios Siassakos / Sean Strong / Helen Talbot

    Trials, Vol 18, Iss 1, Pp 1-

    study protocol for a randomised controlled trial

    2017  Volume 12

    Abstract: Abstract Background Surgical site infections (SSIs) are common, occurring in up to 25% of > 4 million operations performed in England each year. Previous trials of the effect of wound dressings on the risk of developing a SSI are of poor quality and ... ...

    Abstract Abstract Background Surgical site infections (SSIs) are common, occurring in up to 25% of > 4 million operations performed in England each year. Previous trials of the effect of wound dressings on the risk of developing a SSI are of poor quality and underpowered. Methods/Design This study is a feasibility and pilot trial to examine the feasibility of a full trial that will compare simple dressings, no dressing and tissue-glue as a dressing. It is examining the overall acceptability of trial participation, identifying opportunities for refinement, testing the feasibility of and validating new outcome tools to assess SSI, wound management issues and patients’ wound symptom experiences. It is also exploring methods for avoiding performance bias and blinding outcome assessors by testing the feasibility of collecting wound photographs taken in theatre immediately after wound closure and, at 4–8 weeks after surgery, taken by participants themselves or their carers. Finally, it is identifying the main cost drivers for an economic evaluation of dressing types. Integrated qualitative research is exploring acceptability and reasons for non-adherence to allocation. Adults undergoing primary elective or unplanned abdominal general surgery or Caesarean section are eligible. The main exclusion criteria are abdominal or other major surgery less than three months before the index operation or contraindication to dressing allocation. The trial is scheduled to recruit for nine months. The findings will be used to inform the design of a main trial. Discussion This pilot trial is the first pragmatic study to randomise participants to no dressing or tissue-glue as a dressing versus a simple dressing. Early evidence from the ongoing pilot shows that recruitment is proceeding well and that the interventions are acceptable to participants. Combined with the qualitative findings, the findings will inform whether a main, large trial is feasible and, if so, how it should be designed. Trial registration ISRCTN49328913 . Registered on 20 ...
    Keywords Pilot study ; Feasibility study ; Randomised controlled trial ; Wound dressing ; Abdominal surgery ; Caesarean section ; Medicine (General) ; R5-920
    Language English
    Publishing date 2017-08-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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