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  1. AU="Helliwell, Alexandra"
  2. AU="Pitman, Roger K"
  3. AU="España-Sanchez, Beatriz Liliana"
  4. AU="Deibel, C M"
  5. AU="Duarte, Aires"
  6. AU="Man Hong"
  7. AU=McDonald Nathan A.

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  1. Article ; Online: Predictors of hospital length of stay and long-term care facility placement in aneurysmal subarachnoid hemorrhage.

    Snow, Ryan / Shamshad, Alizeh / Helliwell, Alexandra / Wendell, Linda C / Thompson, Bradford B / Furie, Karen L / Reznik, Michael E / Mahta, Ali

    World neurosurgery: X

    2024  Volume 22, Page(s) 100320

    Abstract: Background: Aneurysmal subarachnoid hemorrhage (aSAH) is frequently associated with complications, extended hospital length of stay (LOS) and high health care related costs. We sought to determine predictors for hospital LOS and discharge disposition to ...

    Abstract Background: Aneurysmal subarachnoid hemorrhage (aSAH) is frequently associated with complications, extended hospital length of stay (LOS) and high health care related costs. We sought to determine predictors for hospital LOS and discharge disposition to a long-term care facility (LTCF) in aSAH patients.
    Methods: We performed a retrospective study of a prospectively collected cohort of consecutive patients with aSAH admitted to an academic referral center from 2016 to 2021. Multiple linear regression was performed to identify predictors for hospital LOS. We then created a 10-point scoring system to predict discharge disposition to a LTCF.
    Results: In a cohort of 318 patients with confirmed aSAH, mean age was 57 years (SD 13.7), 61% were female and 70% were white. Hospital LOS was longer for survivors (median 19 days, IQR 14-25) than for non-survivors (median 5 days, IQR 2-8;
    Conclusions: VPS requirement and aSAH related complications were associated with longer hospital LOS compared to other factors. LTCF score has high accuracy in predicting discharge disposition to a LTCF.
    Language English
    Publishing date 2024-02-25
    Publishing country United States
    Document type Journal Article
    ISSN 2590-1397
    ISSN (online) 2590-1397
    DOI 10.1016/j.wnsx.2024.100320
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Highs and Lows: Dysnatremia and Patient Outcomes in Aneurysmal Subarachnoid Hemorrhage.

    Helliwell, Alexandra / Snow, Ryan / Wendell, Linda C / Thompson, Bradford B / Reznik, Michael E / Furie, Karen L / Mahta, Ali

    World neurosurgery

    2023  Volume 173, Page(s) e298–e305

    Abstract: Background: Disturbances in serum sodium concentration (dysnatremia) are common following aneurysmal subarachnoid hemorrhage (aSAH), but its direct impact on outcomes is not well understood. This study aimed to examine the association between ... ...

    Abstract Background: Disturbances in serum sodium concentration (dysnatremia) are common following aneurysmal subarachnoid hemorrhage (aSAH), but its direct impact on outcomes is not well understood. This study aimed to examine the association between dysnatremia following aSAH and patient outcomes.
    Methods: A retrospective cohort study of consecutive patients with aSAH who were admitted to an academic referral center between 2015 and 2021 was performed. Multivariate logistic regression was used to test the association of dysnatremia and outcomes including modified Rankin Scale score at 3 months after discharge and vasospasm. Multiple linear regression was used to test the association of hospital length of stay and dysnatremia.
    Results: We included 320 patients with confirmed aneurysmal etiology (mean [SD] age = 57.8 [14.3] years; 61% female; 70% White). No independent associations were found between hyponatremia or hypernatremia and functional outcome or vasospasm. However, hospital length of stay was longer in patients with hypernatremia (7 more days; 95% confidence interval = 4.4-9.6, P < 0.001) independent of age, Hunt and Hess grade, modified Fisher score, delayed cerebral ischemia, and other hospital complications.
    Conclusions: Although dysnatremia may not directly impact functional outcome or vasospasm risk, hypernatremia may prolong hospital length of stay. Judicious use of hypertonic saline solutions and avoidance of unnecessary dysnatremia in patients with aSAH should be considered.
    MeSH term(s) Humans ; Female ; Middle Aged ; Male ; Subarachnoid Hemorrhage/complications ; Subarachnoid Hemorrhage/therapy ; Hypernatremia ; Retrospective Studies ; Sodium ; Hyponatremia/complications ; Vasospasm, Intracranial/complications
    Chemical Substances Sodium (9NEZ333N27)
    Language English
    Publishing date 2023-02-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2534351-8
    ISSN 1878-8769 ; 1878-8750
    ISSN (online) 1878-8769
    ISSN 1878-8750
    DOI 10.1016/j.wneu.2023.02.043
    Database MEDical Literature Analysis and Retrieval System OnLINE

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