LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 103

Search options

  1. Book: Yao & Artusio's anesthesiology

    Yao, Fun-Sun F. / Hemmings, Hugh C. / Malhotra, Vinod / Fong, Jill

    problem-oriented patient management

    2021  

    Title variant Yao and Artusio's anesthesiology ; Anesthesiology
    Author's details [edited by] Fun-Sun F. Yao, Hugh C. Hemmings, Jr., Vinod Malhotra, Jill Fong
    Keywords Anesthesia
    Language English
    Size xx, 1256 Seiten, Illustrationen, Diagramme
    Edition Ninth edition
    Publisher Wolters Kluwer
    Publishing place Philadelphia
    Publishing country United States
    Document type Book
    Note Zugang zur Online-Ausgabe über Code ; Includes bibliographical references and index
    HBZ-ID HT020997700
    ISBN 9781975120016 ; 1975120019
    Database Catalogue ZB MED Medicine, Health

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2021 A 1031 available for loan (reading room) Lesesaal EG
    Zugang zu Online-Ausgabe über Code aus lizenzrechtlichen Gründen nicht verfügbar

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Book: Pharmacology and physiology for anesthesia

    Hemmings, Hugh C. / Egan, Talmage D.

    foundations and clinical application

    (Expert consult)

    2013  

    Author's details Hugh C. Hemmings Jr. ; Talmage D. Egan
    Series title Expert consult
    Keywords Anesthesia ; Pharmacological Processes ; Physiological Processes
    Language English
    Size XIV, 690 S. : Ill., graph. Darst.
    Publisher Elsevier Saunders
    Publishing place Philadelphia, Pa
    Publishing country United States
    Document type Book
    Note Includes bibliographical references and index
    Accompanying material Zugang zur Internetausgabe über Code
    HBZ-ID HT017596260
    ISBN 978-1-4377-1679-5 ; 1-4377-1679-2
    Database Catalogue ZB MED Medicine, Health

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2013 A 277 available for loan (reading room) Lesesaal EG
    Zugang zur Internetausgabe über Code aus lizenzrechtlichen Gründen nicht verfügbar

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article ; Online: Turning the page on 2021: an eventful year for the British Journal of Anaesthesia.

    Hemmings, Hugh C

    British journal of anaesthesia

    2021  Volume 128, Issue 1, Page(s) 1–3

    Abstract: The British Journal of Anaesthesia (BJA) had an eventful 2021, following what was a cataclysmic 2020 for the whole world. Despite the tragic challenges of multiple waves of the COVID-19 pandemic and the unparalleled burdens this created for everyone ... ...

    Abstract The British Journal of Anaesthesia (BJA) had an eventful 2021, following what was a cataclysmic 2020 for the whole world. Despite the tragic challenges of multiple waves of the COVID-19 pandemic and the unparalleled burdens this created for everyone working in anaesthesia and critical care, the BJA underwent a major transformation during 2021. The BJA strongly supported research and education relevant to the pandemic, and to the broader missions of anaesthesia, critical, and pain medicine. Innovations to the BJA in 2021 included a special section on COVID-19 and the Anaesthetist; a new open access journal in the BJA stable; creation of a new social media editor position; new webinar and author interview series; transition to a new manuscript management system; and a move away from paper to electronic publication.
    MeSH term(s) Anesthesia ; Anesthesiology ; COVID-19 ; Humans ; Periodicals as Topic/trends ; Publishing/trends ; Social Media ; United Kingdom
    Language English
    Publishing date 2021-11-22
    Publishing country England
    Document type Editorial
    ZDB-ID 80074-0
    ISSN 1471-6771 ; 0007-0912
    ISSN (online) 1471-6771
    ISSN 0007-0912
    DOI 10.1016/j.bja.2021.11.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Uk I Zs.80: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article ; Online: Effects of General Anesthetics on Synaptic Transmission and Plasticity.

    Platholi, Jimcy / Hemmings, Hugh C

    Current neuropharmacology

    2023  Volume 20, Issue 1, Page(s) 27–54

    Abstract: General anesthetics depress excitatory and/or enhance inhibitory synaptic transmission principally by modulating the function of glutamatergic or GABAergic synapses, respectively, with relative anesthetic agent-specific mechanisms. Synaptic signaling ... ...

    Abstract General anesthetics depress excitatory and/or enhance inhibitory synaptic transmission principally by modulating the function of glutamatergic or GABAergic synapses, respectively, with relative anesthetic agent-specific mechanisms. Synaptic signaling proteins, including ligand- and voltage-gated ion channels, are targeted by general anesthetics to modulate various synaptic mechanisms, including presynaptic neurotransmitter release, postsynaptic receptor signaling, and dendritic spine dynamics to produce their characteristic acute neurophysiological effects. As synaptic structure and plasticity mediate higher-order functions such as learning and memory, long-term synaptic dysfunction following anesthesia may lead to undesirable neurocognitive consequences depending on the specific anesthetic agent and the vulnerability of the population. Here we review the cellular and molecular mechanisms of transient and persistent general anesthetic alterations of synaptic transmission and plasticity.
    MeSH term(s) Anesthetics, General/pharmacology ; Humans ; Learning ; Synapses ; Synaptic Transmission
    Chemical Substances Anesthetics, General
    Language English
    Publishing date 2023-02-28
    Publishing country United Arab Emirates
    Document type Journal Article ; Review
    ZDB-ID 2192352-8
    ISSN 1875-6190 ; 1570-159X
    ISSN (online) 1875-6190
    ISSN 1570-159X
    DOI 10.2174/1570159X19666210803105232
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 6150: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article: Relevance of Cortical and Hippocampal Interneuron Functional Diversity to General Anesthetic Mechanisms: A Narrative Review.

    Speigel, Iris A / Hemmings, Hugh C

    Frontiers in synaptic neuroscience

    2022  Volume 13, Page(s) 812905

    Abstract: General anesthetics disrupt brain processes involved in consciousness by altering synaptic patterns of excitation and inhibition. In the cerebral cortex and hippocampus, GABAergic inhibition is largely mediated by inhibitory interneurons, a heterogeneous ...

    Abstract General anesthetics disrupt brain processes involved in consciousness by altering synaptic patterns of excitation and inhibition. In the cerebral cortex and hippocampus, GABAergic inhibition is largely mediated by inhibitory interneurons, a heterogeneous group of specialized neuronal subtypes that form characteristic microcircuits with excitatory neurons. Distinct interneuron subtypes regulate specific excitatory neuron networks during normal behavior, but how these interneuron subtypes are affected by general anesthetics is unclear. This narrative review summarizes current principles of the synaptic architecture of cortical and interneuron subtypes, their contributions to different forms of inhibition, and their roles in distinct neuronal microcircuits. The molecular and cellular targets in these circuits that are sensitive to anesthetics are reviewed in the context of how anesthetics impact interneuron function in a subtype-specific manner. The implications of this functional interneuron diversity for mechanisms of anesthesia are discussed, as are their implications for anesthetic-induced changes in neural plasticity and overall brain function.
    Language English
    Publishing date 2022-01-26
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2592086-8
    ISSN 1663-3563
    ISSN 1663-3563
    DOI 10.3389/fnsyn.2021.812905
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article ; Online: Change management: the British Journal of Anaesthesia in 2018.

    Hemmings, Hugh C

    British journal of anaesthesia

    2018  Volume 122, Issue 1, Page(s) 1–3

    MeSH term(s) Anesthesiology/trends ; Periodicals as Topic/statistics & numerical data ; Periodicals as Topic/trends ; Publishing/statistics & numerical data ; Publishing/trends ; United Kingdom
    Language English
    Publishing date 2018-12-19
    Publishing country England
    Document type Editorial
    ZDB-ID 80074-0
    ISSN 1471-6771 ; 0007-0912
    ISSN (online) 1471-6771
    ISSN 0007-0912
    DOI 10.1016/j.bja.2018.12.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Uk I Zs.80: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Book: Foundations of anesthesia

    Hemmings, Hugh C. / Hopkins, Philip M.

    basic sciences for clinical practice

    2006  

    Title variant Anesthesia
    Author's details Hugh C. Hemmings ; Philip M. Hopkins
    Keywords Anesthesia ; Biological Sciences
    Language English
    Size XV, 903 S. : zahlr. Ill., graph. Darst.
    Edition 2. ed.
    Publisher Mosby
    Publishing place Philadelphia, Pa
    Publishing country United States
    Document type Book
    Note Systemvoraussetzungen: Windows: Windows 98 or higher; Pentium processor-based PC; 16 MB RAM (32 MB recommended); 10 MB of available hard-disk space; 2x or faster CD-ROM drive; VGA monitor supporting thousands of colors (16-bit). - Macintosh: Apple Power Macintosh Mac OS version 9 or later; 64 MB of available RAM; 2x or faster CD-ROM drive
    Accompanying material 1 CD-ROM (12 cm) + Begleith. (2 Bl.)
    HBZ-ID HT014441725
    ISBN 0-323-03707-0 ; 978-0-323-03707-5
    Database Catalogue ZB MED Medicine, Health

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2005 A 4666 order for loan Magazin
    2005 MO 733 <<[Begleitmaterial]>> order for loan Magazin

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Article ; Online: Selective inhibition of gamma aminobutyric acid release from mouse hippocampal interneurone subtypes by the volatile anaesthetic isoflurane.

    Speigel, Iris A / Hemmings, Hugh C

    British journal of anaesthesia

    2021  Volume 127, Issue 4, Page(s) 587–599

    Abstract: Background: The cellular and molecular mechanisms by which general anaesthesia occurs is poorly understood. Hippocampal interneurone subpopulations, which are critical regulators of cognitive function, have diverse neurophysiological and synaptic ... ...

    Abstract Background: The cellular and molecular mechanisms by which general anaesthesia occurs is poorly understood. Hippocampal interneurone subpopulations, which are critical regulators of cognitive function, have diverse neurophysiological and synaptic properties, but their responses to anaesthetics are unclear.
    Methods: We used live-cell imaging of fluorescent biosensors expressed in mouse hippocampal neurones to delineate interneurone subtype-specific effects of isoflurane on synaptic vesicle exocytosis. The role of voltage-gated sodium channel (Na
    Results: Clinically relevant concentrations of isoflurane differentially inhibited synaptic vesicle exocytosis: to 83.1% (11.7%) of control in parvalbumin-expressing interneurones, and to 58.6% (13.3%) and 64.5% (8.5%) of control in somatostatin-expressing interneurones and glutamatergic neurones, respectively. The relative expression of Na
    Conclusions: Isoflurane inhibits synaptic vesicle exocytosis from hippocampal glutamatergic neurones and GABAergic interneurones in a cell-type-specific manner depending on their expression of voltage-gated sodium channel subtypes.
    MeSH term(s) Anesthetics, Inhalation/pharmacology ; Animals ; Exocytosis/drug effects ; Female ; Gene Knockdown Techniques ; Hippocampus/drug effects ; Hippocampus/metabolism ; Isoflurane/pharmacology ; Male ; Mice ; Mice, Transgenic ; Neurons/drug effects ; Neurons/metabolism ; Synaptic Transmission/drug effects ; Voltage-Gated Sodium Channels/genetics ; gamma-Aminobutyric Acid/metabolism
    Chemical Substances Anesthetics, Inhalation ; Voltage-Gated Sodium Channels ; gamma-Aminobutyric Acid (56-12-2) ; Isoflurane (CYS9AKD70P)
    Language English
    Publishing date 2021-08-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 80074-0
    ISSN 1471-6771 ; 0007-0912
    ISSN (online) 1471-6771
    ISSN 0007-0912
    DOI 10.1016/j.bja.2021.06.042
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Uk I Zs.80: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Book: Regulatory protein modification

    Hemmings, Hugh C.

    techniques and protocols

    (Neuromethods ; 30)

    1997  

    Author's details ed. by Hugh C. Hemmings
    Series title Neuromethods ; 30
    Collection
    Keywords Neurons / physiology / laboratory manuals ; Phosphorylation / laboratory manuals ; Protein Processing, Post-Translational ; Protein Engineering / methods / laboratory manuals ; Protein Kinases / laboratory manuals ; Synaptosomes / chemistry / laboratory manuals ; Proteine ; Methode
    Subject Methodik ; Verfahren ; Technik ; Methoden ; Eiweiss ; Protein
    Language English
    Size XIV, 445 S. : Ill., graph. Darst.
    Publisher Humana Press
    Publishing place Totowa, NJ
    Publishing country United States
    Document type Book
    HBZ-ID HT007417238
    ISBN 0-89603-415-1 ; 978-0-89603-415-0
    Database Catalogue ZB MED Medicine, Health

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    1997 A 3391 order for loan Magazin

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article ; Online: Isoflurane Alters Presynaptic Endoplasmic Reticulum Calcium Dynamics in Wild-Type and Malignant Hyperthermia-Susceptible Rodent Hippocampal Neurons.

    Osman, Vanessa / Speigel, Iris / Patel, Kishan / Hemmings, Hugh C

    eNeuro

    2023  Volume 10, Issue 8

    Abstract: Volatile anesthetics reduce excitatory synaptic transmission by both presynaptic and postsynaptic mechanisms which include inhibition of depolarization-evoked increases in presynaptic ... ...

    Abstract Volatile anesthetics reduce excitatory synaptic transmission by both presynaptic and postsynaptic mechanisms which include inhibition of depolarization-evoked increases in presynaptic Ca
    MeSH term(s) Rats ; Mice ; Animals ; Calcium ; Isoflurane/pharmacology ; Malignant Hyperthermia/genetics ; Ryanodine Receptor Calcium Release Channel ; Rodentia ; Endoplasmic Reticulum ; Neurons ; Hippocampus
    Chemical Substances Calcium (SY7Q814VUP) ; Isoflurane (CYS9AKD70P) ; Ryanodine Receptor Calcium Release Channel
    Language English
    Publishing date 2023-08-29
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2800598-3
    ISSN 2373-2822 ; 2373-2822
    ISSN (online) 2373-2822
    ISSN 2373-2822
    DOI 10.1523/ENEURO.0114-23.2023
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top