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  1. Article: Clinical hypnotherapy for smoking cessation.

    Hempstead, J S

    Professional nurse (London, England)

    2001  Volume 17, Issue 4, Page(s) 265

    MeSH term(s) Humans ; Hypnosis ; Smoking Cessation/methods
    Language English
    Publishing date 2001-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 639486-3
    ISSN 0266-8130
    ISSN 0266-8130
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: In vivo evaluation of battery-operated light-emitting diode-based photodynamic therapy efficacy using tumor volume and biomarker expression as endpoints.

    Mallidi, Srivalleesha / Mai, Zhiming / Rizvi, Imran / Hempstead, Joshua / Arnason, Stephen / Celli, Jonathan / Hasan, Tayyaba

    Journal of biomedical optics

    2015  Volume 20, Issue 4, Page(s) 48003

    Abstract: In view of the increase in cancer-related mortality rates in low- to middle-income countries (LMIC), there is an urgent need to develop economical therapies that can be utilized at minimal infrastructure institutions. Photodynamic therapy (PDT), a ... ...

    Abstract In view of the increase in cancer-related mortality rates in low- to middle-income countries (LMIC), there is an urgent need to develop economical therapies that can be utilized at minimal infrastructure institutions. Photodynamic therapy (PDT), a photochemistry-based treatment modality, offers such a possibility provided that low-cost light sources and photosensitizers are available. In this proof-of-principle study, we focus on adapting the PDT light source to a low-resource setting and compare an inexpensive, portable, battery-powered light-emitting diode (LED) light source with a standard, high-cost laser source. The comparison studies were performed in vivo in a xenograft murine model of human squamous cell carcinoma subjected to 5-aminolevulinic acid-induced protoporphyrin IX PDT. We observed virtually identical control of the tumor burden by both the LED source and the standard laser source. Further insights into the biological response were evaluated by biomarker analysis of necrosis, microvessel density, and hypoxia [carbonic anhydrase IX (CAIX) expression] among groups of control, LED-PDT, and laser-PDT treated mice. There is no significant difference in the percent necrotic volume and CAIX expression in tumors that were treated with the two different light sources. These encouraging preliminary results merit further investigations in orthotopic animal models of cancers prevalent in LMICs.
    MeSH term(s) Animals ; Biomarkers, Tumor/analysis ; Carbonic Anhydrase IX ; Carbonic Anhydrases/analysis ; Cell Line, Tumor ; Electric Power Supplies ; Equipment Design ; Equipment Failure Analysis ; Female ; Lighting/instrumentation ; Mice ; Mice, Nude ; Neoplasms, Experimental/chemistry ; Neoplasms, Experimental/drug therapy ; Neoplasms, Experimental/pathology ; Photochemotherapy/instrumentation ; Photosensitizing Agents/therapeutic use ; Protoporphyrins/therapeutic use ; Semiconductors ; Treatment Outcome ; Tumor Burden
    Chemical Substances Biomarkers, Tumor ; Photosensitizing Agents ; Protoporphyrins ; protoporphyrin IX (C2K325S808) ; Carbonic Anhydrase IX (EC 4.2.1.1) ; Carbonic Anhydrases (EC 4.2.1.1) ; Car9 protein, mouse (EC 4.2.1.1.)
    Language English
    Publishing date 2015-04-14
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 1309154-2
    ISSN 1560-2281 ; 1083-3668
    ISSN (online) 1560-2281
    ISSN 1083-3668
    DOI 10.1117/1.JBO.20.4.048003
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  3. Article ; Online: Low-cost photodynamic therapy devices for global health settings: Characterization of battery-powered LED performance and smartphone imaging in 3D tumor models.

    Hempstead, Joshua / Jones, Dustin P / Ziouche, Abdelali / Cramer, Gwendolyn M / Rizvi, Imran / Arnason, Stephen / Hasan, Tayyaba / Celli, Jonathan P

    Scientific reports

    2015  Volume 5, Page(s) 10093

    Abstract: A lack of access to effective cancer therapeutics in resource-limited settings is implicated in global cancer health disparities between developed and developing countries. Photodynamic therapy (PDT) is a light-based treatment modality that has exhibited ...

    Abstract A lack of access to effective cancer therapeutics in resource-limited settings is implicated in global cancer health disparities between developed and developing countries. Photodynamic therapy (PDT) is a light-based treatment modality that has exhibited safety and efficacy in the clinic using wavelengths and irradiances achievable with light-emitting diodes (LEDs) operated on battery power. Here we assess low-cost enabling technology to extend the clinical benefit of PDT to regions with little or no access to electricity or medical infrastructure. We demonstrate the efficacy of a device based on a 635 nm high-output LED powered by three AA disposable alkaline batteries, to achieve strong cytotoxic response in monolayer and 3D cultures of A431 squamous carcinoma cells following photosensitization by administering aminolevulinic acid (ALA) to induce the accumulation of protoporphyrin IX (PpIX). Here we characterize challenges of battery-operated device performance, including battery drain and voltage stability specifically over relevant PDT dose parameters. Further motivated by the well-established capacity of PDT photosensitizers to serve as tumour-selective fluorescence contrast agents, we demonstrate the capability of a consumer smartphone with low-cost add-ons to measure concentration-dependent PpIX fluorescence. This study lays the groundwork for the on-going development of image-guided ALA-PDT treatment technologies for global health applications.
    MeSH term(s) Humans ; Imaging, Three-Dimensional/methods ; Neoplasms/drug therapy ; Neoplasms/pathology ; Photochemotherapy/instrumentation ; Photochemotherapy/methods ; Smartphone
    Language English
    Publishing date 2015-05-12
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/srep10093
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Treatment of immune-mediated keratitis in horses with episcleral silicone matrix cyclosporine delivery devices.

    Gilger, Brian C / Stoppini, Riccardo / Wilkie, David A / Clode, Alison B / Pinto, Nelson H / Hempstead, Julie / Gerding, Joseph / Salmon, Jacklyn H

    Veterinary ophthalmology

    2014  Volume 17 Suppl 1, Page(s) 23–30

    Abstract: Purpose: To describe the use of episcleral silicone matrix cyclosporine (ESMC) drug delivery devices in horses with immune-mediated keratitis (IMMK) with evaluation of tolerability and efficacy in long-term control of inflammation.: Methods: ... ...

    Abstract Purpose: To describe the use of episcleral silicone matrix cyclosporine (ESMC) drug delivery devices in horses with immune-mediated keratitis (IMMK) with evaluation of tolerability and efficacy in long-term control of inflammation.
    Methods: Retrospective study. ESMC implants (1.2 cm length, 30% wt/wt cyclosporine (CsA) in silicone; with approximately 2 μg/day steady-state release for at least 400 days) were used.
    Results: Nineteen horses (20 eyes) received two or more ESMC implants for superficial stromal (n = 9), midstromal (n = 3), or endothelial (n = 5) IMMK. Three additional horses received two or more ESMC implants for pigmentary keratouveitis (PK). Nine eyes of eight horses with superficial and five eyes of five horses with endothelial IMMK were well controlled after placement of ESMC implants (mean follow-up 176.8 and 207.2 days, respectively). Horses with midstromal IMMK and PK were not controlled with ESMC implants alone, but instead required frequent use of other medications or surgery to control the disease. The mean duration of disease prior to ESMC implantation of horses with midstromal IMMK was 495 ± 203.9 days, compared with 121.6 ± 92.7 days with superficial IMMK. ESMC implants were well tolerated by all horses without documented loss of the device.
    Conclusions: Results from this preliminary retrospective study suggest that the ESMC implants were well tolerated and associated with treatment success with superficial and endothelial IMMK, especially if placed early in the disease process. Further study is needed to determine the duration of efficacy, number of implants required, and better therapies for chronic midstromal IMMK and pigmentary keratouveitis.
    MeSH term(s) Animals ; Cyclosporine/administration & dosage ; Cyclosporine/therapeutic use ; Drug Implants/administration & dosage ; Female ; Horse Diseases/drug therapy ; Horses ; Immunosuppressive Agents/administration & dosage ; Immunosuppressive Agents/therapeutic use ; Keratitis/drug therapy ; Keratitis/veterinary ; Male ; Sclera ; Silicones ; Treatment Outcome
    Chemical Substances Drug Implants ; Immunosuppressive Agents ; Silicones ; Cyclosporine (83HN0GTJ6D)
    Language English
    Publishing date 2014-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 2011043-1
    ISSN 1463-5224 ; 1463-5216
    ISSN (online) 1463-5224
    ISSN 1463-5216
    DOI 10.1111/vop.12087
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  5. Article: A further consideration in the application of an analysis-of-variance model for the intrasubject replication design.

    Kratochwill, T / Alden, K / Demuth, D / Dawson, D / Panicucci, C / Arntson, P / McMurray, N / Hempstead, J / Levin, J

    Journal of applied behavior analysis

    2006  Volume 7, Issue 4, Page(s) 629–633

    Abstract: It is argued that the analysis-of-variance model is inappropriate for assessing treatment effects in single-subject designs. In particular, such designs are demonstrated to violate the crucial assumption concerning the statistical independence of ... ...

    Abstract It is argued that the analysis-of-variance model is inappropriate for assessing treatment effects in single-subject designs. In particular, such designs are demonstrated to violate the crucial assumption concerning the statistical independence of observations. Alternative methods of data analysis are suggested.
    Language English
    Publishing date 2006-06-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 218065-0
    ISSN 1938-3703 ; 0021-8855
    ISSN (online) 1938-3703
    ISSN 0021-8855
    DOI 10.1901/jaba.1974.7-629
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  6. Article: Thymosin beta 10 levels in developing human brain and its regulation by retinoic acid in the HTB-10 neuroblastoma.

    Hall, A K / Hempstead, J / Morgan, J I

    Brain research. Molecular brain research

    1990  Volume 8, Issue 2, Page(s) 129–135

    Abstract: Human fetal brain expresses high levels of a polypeptide identified by protein biochemistry and molecular cloning as thymosin beta 10. Within the first 18 months after birth, the thymosin beta 10 content of human brain falls to undetectable levels. In ... ...

    Abstract Human fetal brain expresses high levels of a polypeptide identified by protein biochemistry and molecular cloning as thymosin beta 10. Within the first 18 months after birth, the thymosin beta 10 content of human brain falls to undetectable levels. In order to establish the molecular basis of this process we screened a number of human tumor cell lines derived from the nervous system for the presence of thymosin beta 10. All of the cell line expressed authentic thymosin beta 10. However, in the HTB-10 neuroblastoma, retinoic acid caused a reduction in the level of thymosin beta 10. This effect of the retinoid was conditional upon its continual presence in the tissue culture medium and was not evident in the other cell lines examined. These results suggest that the thymosin beta 10 gene may be a target for retinoids in the developing nervous system.
    MeSH term(s) Amino Acid Sequence ; Base Sequence ; Brain/embryology ; Brain/growth & development ; Brain Chemistry ; Gene Expression Regulation/drug effects ; Gene Expression Regulation, Neoplastic/drug effects ; Genes ; Humans ; Infant ; Infant, Newborn ; Molecular Sequence Data ; Neoplasm Proteins/biosynthesis ; Nerve Tissue Proteins/biosynthesis ; Nerve Tissue Proteins/genetics ; Neuroblastoma/pathology ; Thymosin/analogs & derivatives ; Thymosin/biosynthesis ; Thymosin/genetics ; Tretinoin/pharmacology ; Tumor Cells, Cultured/drug effects ; Tumor Cells, Cultured/metabolism
    Chemical Substances Neoplasm Proteins ; Nerve Tissue Proteins ; Tretinoin (5688UTC01R) ; Thymosin (61512-21-8) ; thymosin beta(10) (87397-91-9)
    Language English
    Publishing date 1990-07
    Publishing country Netherlands
    Document type Journal Article ; Research Support, U.S. Gov't, P.H.S.
    ZDB-ID 632883-0
    ISSN 1872-6941 ; 0169-328X
    ISSN (online) 1872-6941
    ISSN 0169-328X
    DOI 10.1016/0169-328x(90)90057-k
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  7. Article: Molecular cloning of a neuron-specific transcript and its regulation during normal and aberrant cerebellar development.

    Sangameswaran, L / Hempstead, J / Morgan, J I

    Proceedings of the National Academy of Sciences of the United States of America

    1989  Volume 86, Issue 14, Page(s) 5651–5655

    Abstract: PEP-19 is a brain-specific polypeptide whose levels increase dramatically during the late maturation of the rodent nervous system. By using immunocytochemistry, PEP-19 is shown to be localized to several regions of the central nervous system, notably ... ...

    Abstract PEP-19 is a brain-specific polypeptide whose levels increase dramatically during the late maturation of the rodent nervous system. By using immunocytochemistry, PEP-19 is shown to be localized to several regions of the central nervous system, notably cerebellum, thalamus caudate putamen, and olfactory bulb. We have isolated a 0.5-kilobase cDNA clone that encodes the entire PEP-19 protein sequence, making this one of the smallest primary transcripts and translation products ever identified in eukaryotes. The cDNA was used to investigate the developmental expression of PEP-19 in rodent brain. PEP-19 mRNA rises from low levels at embryonic day 17 of gestation in the rat to a plateau value by day 18 postpartum. This mirrored the levels of the protein determined by radioimmunoassay. Since the rise coincided with the formation of synaptic contacts onto Purkinje cells (a major site of PEP-19 expression), the hypothesis was tested that the activity and/or presence of afferent input modulated PEP-19 expression. Parallel fiber innervation was disrupted either by killing granule cells with the cytostatic agent methylazoxymethanol or by examining PEP-19 levels in cerebellar granuloprival mutant mice (reeler and weaver). The influence of climbing fiber input was assessed by either eliminating them with 3-acetylpyridine or stimulating them with harmaline in both neonatal and mature rats. None of the above altered PEP-19 gene expression in cerebellum, leading us to propose that the signals triggering the PEP-19 gene do not emanate from granule cells or neurons in the olivary nucleus. However, preliminary evidence suggests that PEP-19 is under posttranscriptional regulation.
    MeSH term(s) Aging ; Amino Acid Sequence ; Animals ; Base Sequence ; Blotting, Northern ; Brain/drug effects ; Brain/growth & development ; Brain/metabolism ; Calmodulin-Binding Proteins ; Cerebellar Diseases/chemically induced ; Cerebellar Diseases/metabolism ; Cerebellum/metabolism ; Cloning, Molecular ; Gene Expression Regulation ; Genes ; Harmaline/pharmacology ; Male ; Methylazoxymethanol Acetate/toxicity ; Mice ; Mice, Mutant Strains ; Molecular Sequence Data ; Mutation ; Nerve Tissue Proteins/genetics ; Pyridines/pharmacology ; RNA, Messenger/genetics ; Rats ; Rats, Inbred Strains ; Reference Values ; Transcription, Genetic/drug effects
    Chemical Substances Calmodulin-Binding Proteins ; Nerve Tissue Proteins ; Pcp4 protein, mouse ; Pcp4 protein, rat ; Pyridines ; RNA, Messenger ; 3-acetylpyridine (00QT8FX306) ; Methylazoxymethanol Acetate (592-62-1) ; Harmaline (CN58I4TOET)
    Language English
    Publishing date 1989-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 209104-5
    ISSN 1091-6490 ; 0027-8424
    ISSN (online) 1091-6490
    ISSN 0027-8424
    DOI 10.1073/pnas.86.14.5651
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  8. Article: Catecholamines in the vasculature of the rat and rabbit: dopamine, norepinephrine, epinephrine.

    Head, R J / Hempstead, J / Berkowitz, B A

    Blood vessels

    1982  Volume 19, Issue 3, Page(s) 135–147

    Abstract: A highly sensitive radioenzymatic assay for the measurement of catecholamines in small blood vessels was applied to the measurement of the levels of norepinephrine (NE), dopamine (DA) and epinephrine (E). The results showed the presence of NE, E and DA ... ...

    Abstract A highly sensitive radioenzymatic assay for the measurement of catecholamines in small blood vessels was applied to the measurement of the levels of norepinephrine (NE), dopamine (DA) and epinephrine (E). The results showed the presence of NE, E and DA in all segments of rat or rabbit vascular tissue analyzed. The predominant catecholamine in the vasculature from both species was NE, and the contents of E and DA were similar for most vessels. Unexpectedly large concentrations of E were associated with rabbit blood vessels.
    MeSH term(s) Animals ; Aorta, Abdominal/analysis ; Catecholamines/analysis ; Dopamine/analysis ; Epinephrine/analysis ; Female ; Male ; Mesenteric Arteries/analysis ; Mesenteric Veins/analysis ; Methyltyrosines/pharmacology ; Muscle, Smooth, Vascular/analysis ; Myocardium/analysis ; Norepinephrine/analysis ; Rabbits ; Rats ; Rats, Inbred Strains ; Vena Cava, Inferior/analysis
    Chemical Substances Catecholamines ; Methyltyrosines ; Dopamine (VTD58H1Z2X) ; Norepinephrine (X4W3ENH1CV) ; Epinephrine (YKH834O4BH)
    Language English
    Publishing date 1982
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 125104-1
    ISSN 0303-6847 ; 0302-2765
    ISSN 0303-6847 ; 0302-2765
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  9. Article: Monoclonal antibodies to mammalian carnosine synthetase.

    Margolis, F L / Grillo, M / Hempstead, J / Morgan, J I

    Journal of neurochemistry

    1987  Volume 48, Issue 2, Page(s) 593–600

    Abstract: A set of mouse monoclonal antibodies has been generated against rabbit muscle carnosine synthetase. The immunoreactivity of these antibodies has been characterized using an immunoassay that permits the separation and direct measurement of the synthetase ... ...

    Abstract A set of mouse monoclonal antibodies has been generated against rabbit muscle carnosine synthetase. The immunoreactivity of these antibodies has been characterized using an immunoassay that permits the separation and direct measurement of the synthetase activity on a second antibody bead complex. Four IgG monoclonal antibodies bind the carnosine synthetase activity from muscle of all mammals tested (mouse, rat, rabbit, cow, dog, and monkey) but not that from chicken muscle. This indicates the mammalian enzymes share epitopes that are absent from the avian enzyme. In addition, relative tissue levels of synthetase activity can be quantified with this immunoassay. Thus, high levels of carnosine synthetase activity are immunoprecipitated from the olfactory tissues of both rat and rabbit. Synthetase activity is generally lower in other tissues (muscle, brain, heart, liver, and gut). Nevertheless, the cross-reactivity of the synthetase from several tissues (olfactory mucosa, muscle, brain, gut, heart, and liver) of a single species indicates the enzyme protein contains similar epitopes in these tissues. Immunoaffinity purification of this low-abundance, unstable enzyme should now be possible for subsequent studies of structure and regulation.
    MeSH term(s) Animals ; Antibodies, Monoclonal ; Cross Reactions ; Immunoglobulin G ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Peptide Synthases/immunology ; Rabbits ; Rats ; Rats, Inbred Strains
    Chemical Substances Antibodies, Monoclonal ; Immunoglobulin G ; Peptide Synthases (EC 6.3.2.-) ; carnosine synthetase (EC 6.3.2.11)
    Language English
    Publishing date 1987-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 80158-6
    ISSN 1471-4159 ; 0022-3042 ; 1474-1644
    ISSN (online) 1471-4159
    ISSN 0022-3042 ; 1474-1644
    DOI 10.1111/j.1471-4159.1987.tb04134.x
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  10. Article ; Online: Measurement of the Positive Muon Anomalous Magnetic Moment to 0.20 ppm.

    Aguillard, D P / Albahri, T / Allspach, D / Anisenkov, A / Badgley, K / Baeßler, S / Bailey, I / Bailey, L / Baranov, V A / Barlas-Yucel, E / Barrett, T / Barzi, E / Bedeschi, F / Berz, M / Bhattacharya, M / Binney, H P / Bloom, P / Bono, J / Bottalico, E /
    Bowcock, T / Braun, S / Bressler, M / Cantatore, G / Carey, R M / Casey, B C K / Cauz, D / Chakraborty, R / Chapelain, A / Chappa, S / Charity, S / Chen, C / Cheng, M / Chislett, R / Chu, Z / Chupp, T E / Claessens, C / Convery, M E / Corrodi, S / Cotrozzi, L / Crnkovic, J D / Dabagov, S / Debevec, P T / Di Falco, S / Di Sciascio, G / Drendel, B / Driutti, A / Duginov, V N / Eads, M / Edmonds, A / Esquivel, J / Farooq, M / Fatemi, R / Ferrari, C / Fertl, M / Fienberg, A T / Fioretti, A / Flay, D / Foster, S B / Friedsam, H / Froemming, N S / Gabbanini, C / Gaines, I / Galati, M D / Ganguly, S / Garcia, A / George, J / Gibbons, L K / Gioiosa, A / Giovanetti, K L / Girotti, P / Gohn, W / Goodenough, L / Gorringe, T / Grange, J / Grant, S / Gray, F / Haciomeroglu, S / Halewood-Leagas, T / Hampai, D / Han, F / Hempstead, J / Hertzog, D W / Hesketh, G / Hess, E / Hibbert, A / Hodge, Z / Hong, K W / Hong, R / Hu, T / Hu, Y / Iacovacci, M / Incagli, M / Kammel, P / Kargiantoulakis, M / Karuza, M / Kaspar, J / Kawall, D / Kelton, L / Keshavarzi, A / Kessler, D S / Khaw, K S / Khechadoorian, Z / Khomutov, N V / Kiburg, B / Kiburg, M / Kim, O / Kinnaird, N / Kraegeloh, E / Krylov, V A / Kuchinskiy, N A / Labe, K R / LaBounty, J / Lancaster, M / Lee, S / Li, B / Li, D / Li, L / Logashenko, I / Lorente Campos, A / Lu, Z / Lucà, A / Lukicov, G / Lusiani, A / Lyon, A L / MacCoy, B / Madrak, R / Makino, K / Mastroianni, S / Miller, J P / Miozzi, S / Mitra, B / Morgan, J P / Morse, W M / Mott, J / Nath, A / Ng, J K / Nguyen, H / Oksuzian, Y / Omarov, Z / Osofsky, R / Park, S / Pauletta, G / Piacentino, G M / Pilato, R N / Pitts, K T / Plaster, B / Počanić, D / Pohlman, N / Polly, C C / Price, J / Quinn, B / Qureshi, M U H / Ramachandran, S / Ramberg, E / Reimann, R / Roberts, B L / Rubin, D L / Santi, L / Schlesier, C / Schreckenberger, A / Semertzidis, Y K / Shemyakin, D / Sorbara, M / Stöckinger, D / Stapleton, J / Still, D / Stoughton, C / Stratakis, D / Swanson, H E / Sweetmore, G / Sweigart, D A / Syphers, M J / Tarazona, D A / Teubner, T / Tewsley-Booth, A E / Tishchenko, V / Tran, N H / Turner, W / Valetov, E / Vasilkova, D / Venanzoni, G / Volnykh, V P / Walton, T / Weisskopf, A / Welty-Rieger, L / Winter, P / Wu, Y / Yu, B / Yucel, M / Zeng, Y / Zhang, C

    Physical review letters

    2023  Volume 131, Issue 16, Page(s) 161802

    Abstract: We present a new measurement of the positive muon magnetic anomaly, a_{μ}≡(g_{μ}-2)/2, from the Fermilab Muon g-2 Experiment using data collected in 2019 and 2020. We have analyzed more than 4 times the number of positrons from muon decay than in our ... ...

    Abstract We present a new measurement of the positive muon magnetic anomaly, a_{μ}≡(g_{μ}-2)/2, from the Fermilab Muon g-2 Experiment using data collected in 2019 and 2020. We have analyzed more than 4 times the number of positrons from muon decay than in our previous result from 2018 data. The systematic error is reduced by more than a factor of 2 due to better running conditions, a more stable beam, and improved knowledge of the magnetic field weighted by the muon distribution, ω[over ˜]_{p}^{'}, and of the anomalous precession frequency corrected for beam dynamics effects, ω_{a}. From the ratio ω_{a}/ω[over ˜]_{p}^{'}, together with precisely determined external parameters, we determine a_{μ}=116 592 057(25)×10^{-11} (0.21 ppm). Combining this result with our previous result from the 2018 data, we obtain a_{μ}(FNAL)=116 592 055(24)×10^{-11} (0.20 ppm). The new experimental world average is a_{μ}(exp)=116 592 059(22)×10^{-11} (0.19 ppm), which represents a factor of 2 improvement in precision.
    Language English
    Publishing date 2023-11-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208853-8
    ISSN 1079-7114 ; 0031-9007
    ISSN (online) 1079-7114
    ISSN 0031-9007
    DOI 10.1103/PhysRevLett.131.161802
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