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  1. Article: Quantitative gait analysis in children with osteogenesis imperfecta: relationship between gait deviations and clinical features.

    De Wouters, Solange / Detrembleur, Christine / Durnez, Anne / Mahaudens, Philippe / Henry, Brice / Schrooyen, Jean / Docquier, Pierre-Louis

    Acta orthopaedica Belgica

    2022  Volume 88, Issue 2, Page(s) 255–262

    Abstract: Osteogenesis imperfecta is a rare congenital disease of connective tissue characterized by recurrent fractures and progressive skeletal deformities which may impact on gait. The aims of this prospective study were to identify gait deviations in children ... ...

    Abstract Osteogenesis imperfecta is a rare congenital disease of connective tissue characterized by recurrent fractures and progressive skeletal deformities which may impact on gait. The aims of this prospective study were to identify gait deviations in children with osteogenesis imperfecta compared to age-matched controls and establish relationships with clinical features. We evaluated 22 patients with different types of osteogenesis imperfecta using three-dimensional gait analysis. The incidence and location of frac- tures, fracture at birth, age at first fracture, use of intramedullary rodding and number of surgical in- terventions in the lower extremities, bone mineral density, hypermobility and number of injections of bisphosphonates were recorded for each patient. Step length was lower in the osteogenesis imperfecta group compared with the control group. Kinematics showed that sagittal pelvic and transversal hip range of motion were higher in the osteogenesis imperfecta group, whereas sagittal knee range of motion during swing phase was reduced. Regarding kinetics, hip flexion moment and hip negative power peak were significantly decreased in the osteogenesis imperfecta group. Mechanical and energetic parameters were considered as normal. The principal component analysis revealed that the bone mineral density was increased in children who had received more in- jections of bisphosphonates and these had also less deficit in kinematic parameters. Main modifications in gait parameters were observed in spatiotemporal, kinematic and kinetic data. More studies are necessary to allow stratification of severity of the osteogenesis imperfecta disease, help improve its challenging multidisciplinary treatment and ob- jectively assess treatment outcomes.
    MeSH term(s) Child ; Diphosphonates/therapeutic use ; Gait ; Gait Analysis ; Humans ; Infant, Newborn ; Osteogenesis Imperfecta/complications ; Prospective Studies
    Chemical Substances Diphosphonates
    Language English
    Publishing date 2022-06-03
    Publishing country Belgium
    Document type Journal Article
    ZDB-ID 210367-9
    ISSN 0001-6462 ; 1784-407X
    ISSN 0001-6462 ; 1784-407X
    DOI 10.52628/88.2.9117
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 37: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Pectus Arcuatum: A Pectus Unlike Any Other.

    Abdellaoui, Sarah / Scalabre, Aurélien / Piolat, Christian / Lavrand, Frédéric / Lachkar, Amane-Allah / Lehn, Anne / Klipfel, Clémence / Henry, Brice / Soldea, Valentin / Hameury, Frédéric / Becmeur, François

    Journal of pediatric surgery

    2023  Volume 58, Issue 9, Page(s) 1679–1685

    Abstract: Background: Pectus arcuatum is often mistaken for a type of pectus carinatum. However, pectus arcuatum is a unique clinical form of pectus caused by premature obliteration of the sternal sutures (manubrial sternum, four sternebrae and xiphoïd process), ... ...

    Abstract Background: Pectus arcuatum is often mistaken for a type of pectus carinatum. However, pectus arcuatum is a unique clinical form of pectus caused by premature obliteration of the sternal sutures (manubrial sternum, four sternebrae and xiphoïd process), whereas pectus carinatum is due to abnormal growth of the costal cartilage. In order to better describe pectus arcuatum, we analysed the files of patients with pectus arcuatum followed in our centers.
    Methods: Multicenter retrospective study of young patients' files diagnosed with pectus arcuatum.
    Results: The clinical diagnosis of pectus arcuatum was made in 34 patients with a mean age at diagnosis of 10.3 years (4-23 years). A chest profile X-ray or a CT scan was performed in 16 patients (47%) and confirmed the diagnosis of PA by the presence of a sternal fusion. It was complete in 12 patients. A malformation was associated in 35% of cases (Noonan syndrome 33%, scoliosis 25% or cardiopathy 16%). 11 patients (32%) had a family history of skeletal malformation. Orthopedic treatment was initiated in 3 patients without any success. 11 patients underwent surgical correction, which was completed in 7 of them.
    Conclusion: The diagnosis of pectus arcuatum is based on clinical experience and if necessary, on a profile chest X-ray showing the fusion of the sternal pieces. It implies the search for any associated malformations (musculoskeletal, cardiac, syndromic). Bracing treatment is useless for pectus arcuatum. Corrective surgery, based on a sternotomy associated with a partial chondro-costal resection, can be performed at the end of growth.
    Level of evidence: IV.
    MeSH term(s) Humans ; Child ; Pectus Carinatum/diagnostic imaging ; Pectus Carinatum/surgery ; Retrospective Studies ; Thoracic Wall/diagnostic imaging ; Thoracic Wall/surgery ; Sternum/diagnostic imaging ; Sternum/surgery ; Musculoskeletal Abnormalities/diagnostic imaging ; Musculoskeletal Abnormalities/surgery ; Funnel Chest/diagnostic imaging ; Funnel Chest/surgery ; Treatment Outcome
    Language English
    Publishing date 2023-03-23
    Publishing country United States
    Document type Multicenter Study ; Journal Article
    ZDB-ID 80165-3
    ISSN 1531-5037 ; 0022-3468
    ISSN (online) 1531-5037
    ISSN 0022-3468
    DOI 10.1016/j.jpedsurg.2023.03.013
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 607: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article: Lung Middle Lobe Laceration Needing Lobectomy as Complication of Nuss Bar Removal.

    Henry, Brice / Lacroix, Valérie / Pirotte, Thierry / Docquier, Pierre-Louis

    Case reports in orthopedics

    2018  Volume 2018, Page(s) 8965641

    Abstract: Minimally invasive procedure for the treatment of pectus excavatum as described by Nuss has been used from 1987. The bar initially introduced blindly is now introduced under thoracoscopic control to increase safety of the procedure. It is usually removed ...

    Abstract Minimally invasive procedure for the treatment of pectus excavatum as described by Nuss has been used from 1987. The bar initially introduced blindly is now introduced under thoracoscopic control to increase safety of the procedure. It is usually removed two to three years after its insertion in a one-day procedure. Complications of the bar removal are rare but potentially serious. We report the case of a serious complication which occurred immediately after the Nuss bar removal. A 15-year-old boy underwent a Nuss procedure for a severe pectus excavatum without relevant complication. The bar has been removed two years after its insertion in a minimally invasive procedure. Unfortunately, he developed in the immediate postoperative period a hemopneumothorax due to a right middle lobe laceration which required a middle lobectomy by thoracotomy for hemostasis. Lesions of intrathoracic organs are a rare but potentially serious complication of the removal of the Nuss bar. We now propose to perform this procedure under thoracoscopic control to avoid it. In our experience, adhesions between the bar and the pleura are always present, and those with potential risk for bleeding or inducing intrathoracic organ lesions are suppressed prior to the bar removal.
    Language English
    Publishing date 2018-02-22
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2684648-2
    ISSN 2090-6757 ; 2090-6749
    ISSN (online) 2090-6757
    ISSN 2090-6749
    DOI 10.1155/2018/8965641
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Gait abnormalities following slipped capital femoral epiphysis treated with in situ fixation.

    Henry, Brice / Detrembleur, Christine / Mahaudens, Philippe / Boulet, Sophie / Docquier, Pierre-Louis

    Gait & posture

    2019  Volume 69, Page(s) 156–161

    Abstract: Background: Slipped capital femoral epiphysis (SCFE) is a common disorder in adolescent for which no consensus exists regarding management. The aim of the present study was to analyze gait modifications following SCFE treated with in situ fixation (ISF) ...

    Abstract Background: Slipped capital femoral epiphysis (SCFE) is a common disorder in adolescent for which no consensus exists regarding management. The aim of the present study was to analyze gait modifications following SCFE treated with in situ fixation (ISF) and to relate it to radiologic stage.
    Research question: To verify if gait biomechanics are impaired in patients with SCFE and to try to determine a degree of slippage from which gait modifications would appear.
    Methods: We evaluated 16 patients treated by ISF for SCFE with slippage ranging from 11° to 61°. Gait variables were compared to normal population according to age and walking speed and were normalized in Z-scores.
    Results: Spatiotemporal parameters, mechanical and energetic variables were inferior to |1.5| Z-scores and considered as normal. Kinematics showed increase of pelvic tilt and hip adduction. Kinetic variables showed modifications with increased hip extension moment. There was also a strong increase in power of hip extensor. Hip extension moment and power of hip extensors were significantly correlated to radiologic stage. Analysis of ROC curves showed a cut-off value of slippage about 25°-30° affecting kinematics of pelvis and hip and kinetic variables.
    Conclusion: The gait variables were close to normal values. Main modifications were observed in kinematic and kinetic data with a significant increase in extension moment and power generated at the operated hip. This could participate to long-term joint degradation observed in SCFE, even in mild slips. The clinical message is to control regularly SCFE with initial slippage greater than >25-30° to allow for early diagnosis of premature hip osteoarthritis.
    MeSH term(s) Adolescent ; Biomechanical Phenomena ; Child ; Female ; Follow-Up Studies ; Gait ; Hip Joint/physiopathology ; Hip Joint/surgery ; Humans ; Kinetics ; Male ; Movement Disorders/diagnosis ; Movement Disorders/etiology ; Movement Disorders/physiopathology ; Orthopedic Procedures ; Osteoarthritis, Hip/diagnosis ; Osteoarthritis, Hip/etiology ; Osteoarthritis, Hip/prevention & control ; Postoperative Complications/diagnosis ; Postoperative Complications/physiopathology ; Range of Motion, Articular ; Retrospective Studies ; Slipped Capital Femoral Epiphyses/physiopathology ; Slipped Capital Femoral Epiphyses/surgery ; Treatment Outcome
    Language English
    Publishing date 2019-01-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 1162323-8
    ISSN 1879-2219 ; 0966-6362
    ISSN (online) 1879-2219
    ISSN 0966-6362
    DOI 10.1016/j.gaitpost.2019.01.036
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3804: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Deformity correction in thoracic adolescent idiopathic scoliosis.

    Pesenti, Sébastien / Lafage, Renaud / Henry, Brice / Kim, Han J / Bolzinger, Manon / Elysée, Jonathan / Cunningham, Mathew / Choufani, Elie / Lafage, Virginie / Blanco, John / Jouve, Jean-Luc / Widmann, Roger

    The bone & joint journal

    2020  Volume 102-B, Issue 3, Page(s) 376–382

    Abstract: Aims: To compare the rates of sagittal and coronal correction for all-pedicle screw instrumentation and hybrid instrumentation using sublaminar bands in the treatment of thoracic adolescent idiopathic scoliosis (AIS).: Methods: We retrospectively ... ...

    Abstract Aims: To compare the rates of sagittal and coronal correction for all-pedicle screw instrumentation and hybrid instrumentation using sublaminar bands in the treatment of thoracic adolescent idiopathic scoliosis (AIS).
    Methods: We retrospectively reviewed the medical records of 124 patients who had undergone surgery in two centres for the correction of Lenke 1 or 2 AIS. Radiological evaluation was carried out preoperatively, in the early postoperative phase, and at two-year follow-up. Parameters measured included coronal Cobb angles and thoracic kyphosis. Postoperative alignment was compared after matching the cohorts by preoperative coronal Cobb angle, thoracic kyphosis, lumbar lordosis, and pelvic incidence.
    Results: A total of 179 patients were available for analysis. After matching, 124 patients remained (62 in each cohort). Restoration of thoracic kyphosis was significantly better in the sublaminar band group than in the pedicle screw group (from 23.7° to 27.5° to 34.0° versus 23.9° to 18.7° to 21.5°; all p < 0.001). When the preoperative thoracic kyphosis was less than 20°, sublaminar bands achieved a normal postoperative thoracic kyphosis, whereas pedicle screws did not. In the coronal plane, pedicle screws resulted in a significantly better correction than sublaminar bands at final follow-up (73.0% versus 59.7%; p < 0.001).
    Conclusion: This is the first study to compare sublaminar bands and pedicle screws for the correction of a thoracic AIS. We have shown that pedicle screws give a good coronal correction which is maintained at two-year follow-up. Conversely, sublaminar bands restore the thoracic kyphosis better while pedicle screws are associated with a flattening of the thoracic spine. In patients with preoperative hypokyphosis, sublaminar bands should be used to restore a proper sagittal profile. Cite this article:
    MeSH term(s) Adolescent ; Female ; Follow-Up Studies ; Humans ; Male ; Pedicle Screws ; Radiography ; Retrospective Studies ; Scoliosis/diagnosis ; Scoliosis/surgery ; Spinal Fusion/methods ; Thoracic Vertebrae/diagnostic imaging ; Thoracic Vertebrae/surgery
    Language English
    Publishing date 2020-03-01
    Publishing country England
    Document type Comparative Study ; Journal Article ; Multicenter Study
    ZDB-ID 2697156-2
    ISSN 2049-4408 ; 2049-4394
    ISSN (online) 2049-4408
    ISSN 2049-4394
    DOI 10.1302/0301-620X.102B3.BJJ-2019-0993.R1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6989: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  6. Article: Impact of Late Holocene climate variability and anthropogenic activities on Biscayne Bay (Florida, U.S.A.): Evidence from diatoms

    Wachnicka, Anna / Evelyn Gaiser / Lynn Wingard / Henry Briceño / Peter Harlem

    Palaeogeography, palaeoclimatology, palaeoecology. 2013 Feb. 01, v. 371

    2013  

    Abstract: Shallow marine ecosystems are experiencing significant environmental alterations as a result of changing climate and increasing human activities along coasts. Intensive urbanization of the southeast Florida coast and intensification of climate change ... ...

    Abstract Shallow marine ecosystems are experiencing significant environmental alterations as a result of changing climate and increasing human activities along coasts. Intensive urbanization of the southeast Florida coast and intensification of climate change over the last few centuries changed the character of coastal ecosystems in the semi-enclosed Biscayne Bay, Florida. In order to develop management policies for the Bay, it is vital to obtain reliable scientific evidence of past ecological conditions. The long-term records of subfossil diatoms obtained from No Name Bank and Featherbed Bank in the Central Biscayne Bay, and from the Card Sound Bank in the neighboring Card Sound, were used to study the magnitude of the environmental change caused by climate variability and water management over the last ~600yr. Analyses of these records revealed that the major shifts in the diatom assemblage structures at No Name Bank occurred in 1956, at Featherbed Bank in 1966, and at Card Sound Bank in 1957. Smaller magnitude shifts were also recorded at Featherbed Bank in 1893, 1942, 1974 and 1983. Most of these changes coincided with severe drought periods that developed during the cold phases of El Niño Southern Oscillation (ENSO), Atlantic Multidecadal Oscillation (AMO) and Pacific Decadal Oscillation (PDO), or when AMO was in warm phase and PDO was in the cold phase. Only the 1983 change coincided with an unusually wet period that developed during the warm phases of ENSO and PDO. Quantitative reconstructions of salinity using the weighted averaging partial least squares (WA-PLS) diatom-based salinity model revealed a gradual increase in salinity at the three coring locations over the last ~600yr, which was primarily caused by continuously rising sea level and in the last several decades also by the reduction of the amount of freshwater inflow from the mainland. Concentration of sediment total nitrogen (TN), total phosphorus (TP) and total organic carbon (TOC) increased in the second half of the 20th century, which coincided with the construction of canals, landfills, marinas and water treatment plants along the western margin of Biscayne Bay. Increased magnitude and rate of the diatom assemblage restructuring in the mid- and late-1900s, suggest that large environmental changes are occurring more rapidly now than in the past.
    Keywords Bacillariophyceae ; El Nino ; anthropogenic activities ; carbon ; climate ; climate change ; coasts ; drought ; freshwater ; issues and policy ; landfills ; marinas ; marine ecosystems ; models ; nitrogen content ; phosphorus ; salinity ; sea level ; sediments ; urbanization ; water management ; water treatment ; Florida
    Language English
    Dates of publication 2013-0201
    Size p. 80-92.
    Publishing place Elsevier B.V.
    Document type Article
    ZDB-ID 417718-6
    ISSN 0031-0182
    ISSN 0031-0182
    DOI 10.1016/j.palaeo.2012.12.020
    Database NAL-Catalogue (AGRICOLA)

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