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  1. AU="Hense, Peter"
  2. AU="Chien, Jung-Ting"
  3. AU="Rashidi, Muhammad Mahdi"
  4. AU="Gryton, Igal"
  5. AU="Carvajal, Zaira Y García"
  6. AU="Li, Kaixun"
  7. AU="Khuituan, Pissared"
  8. AU="L.Milano, "
  9. AU="Chandramouli, Vaishnavi"
  10. AU="Jose Luis Lavín"
  11. AU="Csályi, Kitti"
  12. AU="Orobello, Nicklas C"
  13. AU=Kim Chang H.
  14. AU="Livingston, Abel"
  15. AU="DeKoven, Mitchell P"
  16. AU="Kubota, Katsumi"

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  1. Artikel ; Online: Evaluation of the cytotoxic and genotoxic potential of printer toner particles in a 3D air-liquid interface, primary cell-based nasal tissue model.

    Meyer, Till Jasper / Tekin, Nursen / Hense, Peter / Ehret-Kasemo, Totta / Lodes, Nina / Stöth, Manuel / Ickrath, Pascal / Gehrke, Thomas / Hagen, Rudolf / Dembski, Sofia / Peer, Michael / Steinke, Maria R / Scherzad, Agmal / Hackenberg, Stephan

    Toxicology letters

    2023  Band 379, Seite(n) 1–10

    Abstract: Printer toner particles (TPs) are a common, potentially hazardous substance, with an unclear toxicological impact on the respiratory mucosa. Most of the airways surface is covered by a ciliated respiratory mucosa, therefore appropriate tissue models of ... ...

    Abstract Printer toner particles (TPs) are a common, potentially hazardous substance, with an unclear toxicological impact on the respiratory mucosa. Most of the airways surface is covered by a ciliated respiratory mucosa, therefore appropriate tissue models of the respiratory epithelium with a high in vivo correlation are necessary for in vitro evaluation of airborne pollutants toxicology and the impact on the functional integrity. The aim of this study is the evaluation of TPs toxicology in a human primary cell-based air-liquid-interface (ALI) model of respiratory mucosa. The TPs were analyzed and characterized by scanning electron microscopy, pyrolysis and X-ray fluorescence spectrometry. ALI models of 10 patients were created using the epithelial cells and fibroblasts derived from nasal mucosa samples. TPs were applied to the ALI models via a modified Vitrocell® cloud and submerged in the dosing 0.89 - 892.96 µg/ cm
    Mesh-Begriff(e) Humans ; Benzene ; Epithelial Cells ; Nasal Mucosa ; Respiratory Mucosa ; Cilia
    Chemische Substanzen Benzene (J64922108F)
    Sprache Englisch
    Erscheinungsdatum 2023-03-11
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article
    ZDB-ID 433788-8
    ISSN 1879-3169 ; 0378-4274
    ISSN (online) 1879-3169
    ISSN 0378-4274
    DOI 10.1016/j.toxlet.2023.03.004
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Evaluation of the cytotoxic and genotoxic potential of printer toner particles in a 3D air-liquid interface, primary cell-based nasal tissue model

    Meyer, Till Jasper / Tekin, Nursen / Hense, Peter / Ehret-Kasemo, Totta / Lodes, Nina / Stöth, Manuel / Ickrath, Pascal / Gehrke, Thomas / Hagen, Rudolf / Dembski, Sofia / Peer, Michael / Steinke, Maria / Scherzad, Agmal / Hackenberg, Stephan

    2023  

    Abstract: 1 ... 10 ... Printer toner particles (TPs) are a common, potentially hazardous substance, with an unclear toxicological impact on the respiratory mucosa. Most of the airways surface is covered by a ciliated respiratory mucosa, therefore appropriate tissue ... ...

    Abstract 1

    10

    Printer toner particles (TPs) are a common, potentially hazardous substance, with an unclear toxicological impact on the respiratory mucosa. Most of the airways surface is covered by a ciliated respiratory mucosa, therefore appropriate tissue models of the respiratory epithelium with a high in vivo correlation are necessary for in vitro evaluation of airborne pollutants toxicology and the impact on the functional integrity. The aim of this study is the evaluation of TPs toxicology in a human primary cell-based air-liquid-interface (ALI) model of respiratory mucosa. The TPs were analyzed and characterized by scanning electron microscopy, pyrolysis and X-ray fluorescence spectrometry. ALI models of 10 patients were created using the epithelial cells and fibroblasts derived from nasal mucosa samples. TPs were applied to the ALI models via a modified Vitrocell® cloud and submerged in the dosing 0.89 - 892.96 µg/ cm2. Particle exposure and intracellular distribution were evaluated by electron microscopy. The MTT assay and the comet assay were used to investigate cytotoxicity and genotoxicity, respectively. The used TPs showed an average particle size of 3 - 8 µm. Mainly carbon, hydrogen, silicon, nitrogen, tin, benzene and benzene derivates were detected as chemical ingredients. By histomorphology and electron microscopy we observed the development of a highly functional, pseudostratified epithelium with a continuous layer of cilia. Using electron microscopy, TPs could be detected on the cilia surface and also intracellularly. Cytotoxicity was detected from 9 µg/ cm2 and higher, but no genotoxicity after ALI and submerged exposure. The ALI with primary nasal cells represents a highly functional model of the respiratory epithelium in terms of histomorphology and mucociliary differentiation. The toxicological results indicate a weak TP-concentration-dependent cytotoxicity. Availability of data and materials: The datasets used and analysed during the current study are available from the corresponding author on ...
    Schlagwörter Air-liquid interface ; Cytotoxicity ; Genotoxicity ; Primary cell based model ; Printer toner particle ; Respiratory epithelium ; DDC::600 Technik ; Medizin ; angewandte Wissenschaften::610 Medizin und Gesundheit
    Thema/Rubrik (Code) 500
    Sprache Englisch
    Erscheinungsland de
    Dokumenttyp Artikel ; Online
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  3. Konferenzbeitrag ; Online: Optimization of a thermochemical process to increase metal recycling from WEEE

    Hense, Peter / Aigner, Jonathan / Franke, Matthias / Reh, Katharina / Hornung, Andreas

    2017  

    Abstract: S.44-45 ... In order to enable a sustainable supply, the recovery of raw materials from secondary resources offers promising potential. Waste Electrical and Electronic Equipment (WEEE) is a source of various metals and polymers, but also includes hazardous ...

    Abstract S.44-45

    In order to enable a sustainable supply, the recovery of raw materials from secondary resources offers promising potential. Waste Electrical and Electronic Equipment (WEEE) is a source of various metals and polymers, but also includes hazardous substances. Therefore, a process for a thermo-chemical treatment of different fractions from WEEE were developed and optimized. With the aim to dehalogenate pyrolysis products and recover base and precious metals from shredder residues as well as gallium, indium and tantalum from Liquid Crystal Displays (LCD) and tantalum capacitors, three thermochemical technology approaches were developed. From shredder residues, not only a concentrate of char and metals was produced, but also liquid and gaseous fuels. The char-metal mixture can be utilized directly in integrated copper smelters in order to recycle contained metals. Special attention was given on how formations of dioxins and furans (PXDD/F) can be suppressed and on how already formed PXDD/F can be decomposed continuously. Regarding LCD, the developed technology is able to extract >99 wt.-% of indium selectively from LCD by using waste polyvinylchloride (PVC). For the last mentioned feedstock, a combination of pyrolytic and mechanical treatment was developed and optimized, which is able to form a concentrate of nearly 80 wt.-% tantalum.
    Schlagwörter WEEE ; PXDD / F ; Shredder Residues ; critical metals
    Thema/Rubrik (Code) 660
    Sprache Englisch
    Erscheinungsland de
    Dokumenttyp Konferenzbeitrag ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  4. Konferenzbeitrag ; Online: Pyrolysis of waste electrical and electronic equipment (WEEE) for recovering metals and energy

    Hense, Peter / Reh, Katharina / Franke, Matthias / Hornung, Andreas

    2015  

    Abstract: S.55-56 ... Waste Electrical and Electronic Equipment (WEEE) is one of the fastest growing waste streams worldwide. This waste stream contains a number of economically relevant base, precious and high-tech metals. However, only a limited number of these ... ...

    Abstract S.55-56

    Waste Electrical and Electronic Equipment (WEEE) is one of the fastest growing waste streams worldwide. This waste stream contains a number of economically relevant base, precious and high-tech metals. However, only a limited number of these metals can be recovered by mechanical treatment. The pyrolysis technology allows a baring and an accumulation of metals from WEEE-fractions without oxidation as well as the generation of high calorific gases and liquids for energetic utilization in a combined heat and power plant. Recovered metals can be used in pyro-metallurgical recycling processes to recover secondary raw materials. In this article, results from pyrolysis batch tests with residuals from a treatment of WEEE are presented. In an ecological assessment the environmental performance of the pyrolysis process is compared to a treatment in a municipal waste incinerator. The results of the ecological assessment clearly evidence that a thermo-chemical treatment of residuals from a WEEE treatment presents a promising option concerning environmental aspects of global warming potential, acidification potential and abiotic resource depletion potential.
    Schlagwörter pyrolysis ; WEEE ; solid residuals ; metal recycling ; ecological assessment ; 620
    Thema/Rubrik (Code) 660
    Sprache Englisch
    Erscheinungsland de
    Dokumenttyp Konferenzbeitrag ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  5. Konferenzbeitrag ; Online: Pyrolysis - a key component for the recovery of metals and energy

    Hense, Peter / Reh, Katharina / Franke, Matthias / Aigner, Jonathan / Mayer, Dominik / Hornung, Andreas / Contin, Andrea

    2015  

    Abstract: S.91-99 ... Waste Electrical and Electronic Equipment (WEEE) is one of the fastest growing waste streams worldwide. This waste stream contains a number of economically relevant base, precious and high-tech metals. However, only a limited number of these ... ...

    Abstract S.91-99

    Waste Electrical and Electronic Equipment (WEEE) is one of the fastest growing waste streams worldwide. This waste stream contains a number of economically relevant base, precious and high-tech metals. However, only a limited number of these metals can be recovered by mechanical treatment. The pyrolysis technology allows a baring and an accumulation of metals from WEEE-fractions without oxidation as well as the generation of high calorific gases and liquids for energetic utilization in a combined heat and power plant. Recovered metals can be used in pyro-metallurgical recycling processes to recover secondary raw materials. In this article, results from pyrolysis batch tests with residuals from a treatment of WEEE are presented. In an ecological assessment the environmental performance of the pyrolysis process is compared to a treatment in a municipal waste incinerator. The results of the ecological assessment clearly evidence that a thermo-chemical treatment of residuals from a WEEE treatment presents a promising option concerning environmental aspects of global warming potential, acidification potential and abiotic resource depletion potential.
    Schlagwörter 620
    Thema/Rubrik (Code) 660
    Sprache Englisch
    Erscheinungsland de
    Dokumenttyp Konferenzbeitrag ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  6. Buch: Nederlands Dans Theater

    Hense, Peter / Utrecht, Luuk

    1981  

    Verfasserangabe Peter Hense; Luuk Utrecht
    Sprache Niederländisch
    Umfang 83 S., Ill, 29 cm
    Verlag Brigg-Verl
    Erscheinungsort Augsburg
    Dokumenttyp Buch
    ISBN 3871011797 ; 9783871011795
    Datenquelle Ehemaliges Sondersammelgebiet Küsten- und Hochseefischerei

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