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  1. Article ; Online: Leflunomide as a therapeutic alternative to methotrexate as a glucocorticoid-sparing agent in polymyalgia rheumatica.

    González-Gay, Miguel A / Heras-Recuero, Elena / Blázquez-Sánchez, Teresa / Castañeda, Santos / Largo, Raquel

    Rheumatology advances in practice

    2024  Volume 8, Issue 2, Page(s) rkae047

    Language English
    Publishing date 2024-03-28
    Publishing country England
    Document type Editorial
    ISSN 2514-1775
    ISSN (online) 2514-1775
    DOI 10.1093/rap/rkae047
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Biopsy-proven giant cell arteritis in an elderly woman diagnosed 11 years earlier with microscopic polyangiitis: two different vasculitis in the same patient separated in time.

    Fernandez-Prado, Raul / García-Fernández, Antía / Avello, Alejandro / Heras-Recuero, Elena / Cannata, Pablo / González-Gay, Miguel A

    Clinical and experimental rheumatology

    2024  Volume 42, Issue 4, Page(s) 938–939

    MeSH term(s) Humans ; Giant Cell Arteritis/complications ; Giant Cell Arteritis/drug therapy ; Giant Cell Arteritis/diagnosis ; Microscopic Polyangiitis/complications ; Microscopic Polyangiitis/drug therapy ; Microscopic Polyangiitis/diagnosis ; Female ; Biopsy ; Aged ; Treatment Outcome ; Temporal Arteries/pathology ; Time Factors
    Language English
    Publishing date 2024-01-02
    Publishing country Italy
    Document type Case Reports ; Letter
    ZDB-ID 605886-3
    ISSN 1593-098X ; 0392-856X
    ISSN (online) 1593-098X
    ISSN 0392-856X
    DOI 10.55563/clinexprheumatol/r847a0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2002: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  3. Article: Polymyalgia rheumatica: when should we suspect an underlying large vessel vasculitis?

    González-Gay, Miguel Angel / Vicente-Rabaneda, Esther F / Heras-Recuero, Elena / Castañeda, Santos

    Clinical and experimental rheumatology

    2023  Volume 41, Issue 4, Page(s) 774–776

    MeSH term(s) Humans ; Polymyalgia Rheumatica/complications ; Polymyalgia Rheumatica/diagnosis ; Polymyalgia Rheumatica/drug therapy ; Giant Cell Arteritis/complications ; Giant Cell Arteritis/diagnosis ; Giant Cell Arteritis/drug therapy ; Fluorodeoxyglucose F18
    Chemical Substances Fluorodeoxyglucose F18 (0Z5B2CJX4D)
    Language English
    Publishing date 2023-03-27
    Publishing country Italy
    Document type Editorial
    ZDB-ID 605886-3
    ISSN 1593-098X ; 0392-856X
    ISSN (online) 1593-098X
    ISSN 0392-856X
    DOI 10.55563/clinexprheumatol/3bozph
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2002: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Lights and shadows on the efficacy of tocilizumab monotherapy in large vessel giant cell arteritis.

    González-Gay, Miguel Ángel / Castañeda, Santos / Heras-Recuero, Elena / Largo, Raquel

    Rheumatology (Oxford, England)

    2023  Volume 63, Issue 1, Page(s) 6–7

    MeSH term(s) Humans ; Giant Cell Arteritis/drug therapy ; Antibodies, Monoclonal, Humanized/therapeutic use ; Treatment Outcome ; Takayasu Arteritis
    Chemical Substances tocilizumab (I031V2H011) ; Antibodies, Monoclonal, Humanized
    Language English
    Publishing date 2023-07-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 1464822-2
    ISSN 1462-0332 ; 1462-0324
    ISSN (online) 1462-0332
    ISSN 1462-0324
    DOI 10.1093/rheumatology/kead358
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.MO 497: Show issues

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  5. Article ; Online: Challenges in the diagnosis of polymyalgia rheumatica and related giant cell arteritis.

    González-Gay, Miguel A / Vicente-Rabaneda, Esther F / Martínez-López, Juan A / Largo, Raquel / Heras-Recuero, Elena / Castañeda, Santos

    Expert review of clinical immunology

    2023  Volume 19, Issue 5, Page(s) 517–526

    Abstract: Introduction: Polymyalgia rheumatica (PMR) has emerged as a relatively common condition in Western countries. Although the diagnosis is relatively straightforward in people over 50 years of age who complain of sudden onset of pain and stiffness in the ... ...

    Abstract Introduction: Polymyalgia rheumatica (PMR) has emerged as a relatively common condition in Western countries. Although the diagnosis is relatively straightforward in people over 50 years of age who complain of sudden onset of pain and stiffness in the shoulder and hip girdles along with elevation of biomarkers of inflammation, manifestations of polymyalgia can also occur in the context of different conditions. For this reason, a complete history and examination is required, including looking for symptoms and signs suggestive of giant cell arteritis (GCA).
    Areas covered: The review describes when and how to identify PMR, as well as when to suspect the presence of associated GCA or multiple conditions mimicking PMR.
    Expert opinion: PMR does not have a specific diagnostic test. For this reason, a thorough clinical history searching for clinical data of GCA is needed. Moreover, the possibility of other diseases mimicking PMR should be considered, particularly when atypical presentation or unusual clinical data are present.
    MeSH term(s) Humans ; Middle Aged ; Giant Cell Arteritis/diagnosis ; Polymyalgia Rheumatica/diagnosis ; Diagnosis, Differential ; Pain/complications
    Language English
    Publishing date 2023-03-15
    Publishing country England
    Document type Case Reports ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2274260-8
    ISSN 1744-8409 ; 1744-666X
    ISSN (online) 1744-8409
    ISSN 1744-666X
    DOI 10.1080/1744666X.2023.2189586
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6661: Show issues Location:
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  6. Article ; Online: Use of risk chart algorithms for the identification of psoriatic arthritis patients at high risk for cardiovascular disease: findings derived from the project CARMA cohort after a 7.5-year follow-up period.

    Polo Y La Borda, Jessica / Castañeda, Santos / Heras-Recuero, Elena / Sánchez-Alonso, Fernando / Plaza, Zulema / García Gómez, Carmen / Ferraz-Amaro, Ivan / Sanchez-Costa, Jesús Tomás / Sánchez-González, Olga Carmen / Turrión-Nieves, Ana Isabel / Perez-Alcalá, Ana / Pérez-García, Carolina / González-Juanatey, Carlos / Llorca, Javier / Gonzalez-Gay, Miguel Angel

    RMD open

    2024  Volume 10, Issue 2

    Abstract: Objective: To assess the predictive value of four cardiovascular (CV) risk algorithms for identifying high-risk psoriatic arthritis (PsA) patients.: Methods: Evaluation of patients with PsA enrolled in the Spanish prospective project CARdiovascular ... ...

    Abstract Objective: To assess the predictive value of four cardiovascular (CV) risk algorithms for identifying high-risk psoriatic arthritis (PsA) patients.
    Methods: Evaluation of patients with PsA enrolled in the Spanish prospective project CARdiovascular in RheuMAtology. Baseline data of 669 PsA patients with no history of CV events at the baseline visit, who were followed in rheumatology outpatient clinics at tertiary centres for 7.5 years, were retrospectively analysed to test the performance of the Systematic Coronary Risk Assessment (SCORE), the modified version (mSCORE) European Alliance of Rheumatology Associations (EULAR) 2015/2016, the SCORE2 algorithm (the updated and improved version of SCORE) and the QRESEARCH risk estimator version 3 (QRISK3).
    Results: Over 4790 years of follow-up, there were 34 CV events, resulting in a linearised rate of 7.10 per 1000 person-years (95% CI 4.92 to 9.92). The four CV risk scales showed strong correlations and all showed significant associations with CV events (p<0.001). SCORE, mSCORE EULAR 2015/2016 and QRISK3 effectively differentiated between low and high CV risk patients, although the cumulative rate of CV events observed over 7.5 years was lower than expected based on the frequency predicted by these risk scales. Additionally, model improvement was observed when combining QRISK3 with any other scale, particularly the combination of QRISK3 and SCORE2, which yielded the lowest Akaike information criterion (411.15) and Bayesian information criterion (420.10), making it the best predictive model.
    Conclusions: Risk chart algorithms are very useful for discriminating PsA at low and high CV risk. An integrated model featuring QRISK3 and SCORE2 yielded the optimal synergy of QRISK3's discrimination ability and SCORE2's calibration accuracy.
    MeSH term(s) Humans ; Cardiovascular Diseases/complications ; Prospective Studies ; Retrospective Studies ; Arthritis, Psoriatic/complications ; Bayes Theorem ; Follow-Up Studies ; Algorithms
    Language English
    Publishing date 2024-04-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 2812592-7
    ISSN 2056-5933 ; 2056-5933
    ISSN (online) 2056-5933
    ISSN 2056-5933
    DOI 10.1136/rmdopen-2024-004207
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: 18F-Fluorodeoxyglucose Positron Emission Tomography-Computed Tomography Findings of Polymyalgia Rheumatica in Patients with Giant Cell Arteritis.

    Heras-Recuero, Elena / Martínez de Bourio-Allona, Marta / Landaeta-Kancev, Laura Cristina / Blázquez-Sánchez, Teresa / Torres-Roselló, Arantxa / Álvarez-Rubio, Miguel / Belhaj-Gandar, Mariam / Martínez-López, Juan Antonio / Martínez-Dhier, Luis / Llorca, Javier / Largo, Raquel / González-Gay, Miguel Ángel

    Journal of clinical medicine

    2023  Volume 12, Issue 22

    Abstract: Objective: Giant cell arteritis (GCA) and polymyalgia rheumatica (PMR) are often overlapping conditions. We studied whether 18F-fluorodeoxyglucose (FDG) positron emission tomography-computed tomography (PET-CT) is useful in identifying PMR in the ... ...

    Abstract Objective: Giant cell arteritis (GCA) and polymyalgia rheumatica (PMR) are often overlapping conditions. We studied whether 18F-fluorodeoxyglucose (FDG) positron emission tomography-computed tomography (PET-CT) is useful in identifying PMR in the setting of large vessel (LV) GCA.
    Methods: LV-GCA patients diagnosed by PET-CT at a tertiary care center for a population of 450,000 people over a two-year period were reviewed. Scoring was performed based on potential significant FDG uptake at up to 16 sites in nine different extravascular areas (SCORE 16). Differences in extravascular sites of significant FDG uptake were evaluated between LV-GCA with a clinical diagnosis of PMR or not.
    Results: Fifty-four patients were diagnosed with LV-GCA by 18F-FDG-PET-CT. Of them, 21 (38.8%) were clinically diagnosed with PMR. Significant extravascular FDG uptake was more frequently observed in those with a clinical diagnosis of PMR. In this sense, the SCORE 16 was higher in those with clinical PMR (5.10 ± 4.05 versus 1.73 ± 2.31 in those without a clinical diagnosis of PMR;
    Conclusions: Significant extravascular 18F-FDG-PET-CT uptake may help establish a clinical diagnosis of PMR in patients with LV-GCA. These patients are more commonly diagnosed with PMR if they have significant FDG uptake in the shoulder, greater trochanter, and lumbar interspinous areas.
    Language English
    Publishing date 2023-11-08
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12226983
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Positron Emission Computed Tomography Spectrum of Large Vessel Vasculitis in a Tertiary Center: Differences in 18F-fluorodeoxyglucose Uptake between Large Vessel Vasculitis with Predominant Cranial and Extracranial Giant Cell Arteritis Phenotypes.

    Heras-Recuero, Elena / Landaeta-Kancev, Laura Cristina / Martínez de Bourio-Allona, Marta / Torres-Rosello, Arantxa / Blázquez-Sánchez, Teresa / Ferraz-Amaro, Iván / Castañeda, Santos / Martínez-López, Juan Antonio / Martínez-Dhier, Luis / Largo, Raquel / González-Gay, Miguel Ángel

    Journal of clinical medicine

    2023  Volume 12, Issue 19

    Abstract: 1) Objective:To assess the spectrum of PET-CT-related large vessel vasculitis (LVV) in a Spanish tertiary center and to determine whether FDG uptake by PET-CT differs between giant cell arteritis (GCA) with predominant cranial or extracranial phenotypes. ...

    Abstract (1) Objective:To assess the spectrum of PET-CT-related large vessel vasculitis (LVV) in a Spanish tertiary center and to determine whether FDG uptake by PET-CT differs between giant cell arteritis (GCA) with predominant cranial or extracranial phenotypes. (2) Methods: The spectrum of patients diagnosed with LVV by PET-CT in a tertiary referral hospital that cares for 450,000 people over a period of two years was reviewed. Moreover, differences in FDG uptake between LVV-GCA with predominantly cranial and extracranial phenotype were analyzed. (3) Results: Eighty patients were diagnosed with LVV by PET-CT. Most were due to systemic vasculitis (
    Language English
    Publishing date 2023-09-24
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12196164
    Database MEDical Literature Analysis and Retrieval System OnLINE

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