LIVIVO - Search results -

Search results

Result 1 - 10 of total 54

Search options

Article ; Online: Abdominal Aspergillosis - an Underdiagnosed Disease? Three Cases of Abdominal Aspergillosis in Severely Immunocompromised Infants.

Hauch, Richard / Jankofsky, Martin / Klohs, Stefan / Herden, Uta / Blohm, Martin / Winkler, Beate

2024 Volume 236, Issue 3, Page(s) 189–192

Title translation	Abdominelle Aspergillose – eine unterdiagnostizierte Erkrankung? Drei Fälle abdomineller Aspergillose in immunkompromittierten Säuglingen.
MeSH term(s)	Female ; Humans ; Infant ; Male ; Antifungal Agents/therapeutic use ; Aspergillosis/diagnosis ; Aspergillosis/drug therapy ; Aspergillosis/immunology ; Diagnosis, Differential ; Immunocompromised Host ; Opportunistic Infections/immunology ; Opportunistic Infections/diagnosis ; Opportunistic Infections/drug therapy ; Severe Combined Immunodeficiency/diagnosis ; Severe Combined Immunodeficiency/complications ; Tomography, X-Ray Computed
Chemical Substances	Antifungal Agents
Language	English
Publishing date	2024-01-30
Publishing country	Germany
Document type	Journal Article ; Case Reports
ZDB-ID	120650-3
ISSN	1439-3824 ; 0300-8630
ISSN (online)	1439-3824
ISSN	0300-8630
DOI	10.1055/a-2233-1021
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Um IV Zs.15: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Details ▾
- See ZB MED holdings
- Order with fees

Article: Liver transplantation in glycogen storage disease type Ib: The role of SGLT2 inhibitors.

Murko, Simona / Peschka, Manuela / Tsiakas, Konstantinos / Schulz-Jürgensen, Sebastian / Herden, Uta / Santer, René

Molecular genetics and metabolism reports

2023 Volume 35, Page(s) 100977

Abstract: We report on liver transplantation in two patients with GSD Ib on treatment with empagliflozin. The use of this SGLT2 inhibitor resulted in a marked decrease of 1,5-anhydroglucitol which has an important role in the development of neutropenia in this ... ...

Abstract	We report on liver transplantation in two patients with GSD Ib on treatment with empagliflozin. The use of this SGLT2 inhibitor resulted in a marked decrease of 1,5-anhydroglucitol which has an important role in the development of neutropenia in this condition. As intended, this caused a significant rise of neutrophil numbers. Liver transplantation alone did not produce the desired effect and our observation argues for continuing SGLT2 inhibitor treatment after transplantation.
Language	English
Publishing date	2023-05-04
Publishing country	United States
Document type	Journal Article
ZDB-ID	2821908-9
ISSN	2214-4269
ISSN	2214-4269
DOI	10.1016/j.ymgmr.2023.100977
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Hepatic Artery Delineation on Ultrasound Volumes Comparing B-Flow and Color Doppler for Postoperative Monitoring of Pediatric Liver Transplants.

Dammann, Elena / Steinmeister, Leonhard / Groth, Michael / Herden, Uta / Fischer, Lutz / Brinkert, Florian / Beime, Jan / Tozakidou, Magdalini / Bannas, Peter / Herrmann, Jochen

Diagnostics (Basel, Switzerland)

2024 Volume 14, Issue 6

Abstract: 1) Background: Accurate hepatic artery (HA) depiction following pediatric liver transplantation (LT) is essential for graft surveillance but challenging on ultrasound (US). This study assesses if improved HA delineation can be achieved by recording two- ... ...

Abstract	(1) Background: Accurate hepatic artery (HA) depiction following pediatric liver transplantation (LT) is essential for graft surveillance but challenging on ultrasound (US). This study assesses if improved HA delineation can be achieved by recording two-dimensional US volumes in Color Doppler (CD) and B-flow technique. (2) Methods: Of 42 consecutive LT, 37 cases were included, and HA delineation was retrospectively rated using a four-point score (0 = HA not detectable, 3 = HA fully detectable, separable from portal vein) within 48 h post-LT (U1) and before discharge (U2). (3) Results: Adding B-flow compared with CD alone showed superior results at neohilar (U1: 2.2 ± 1.0 vs. 1.1 ± 0.8,
Language	English
Publishing date	2024-03-14
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662336-5
ISSN	2075-4418
ISSN	2075-4418
DOI	10.3390/diagnostics14060617
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: [No title information]

Hauch, Richard / Jankofsky, Martin / Klohs, Stefan / Herden, Uta / Blohm, Martin / Winkler, Beate

Klinische Pädiatrie

2024 Volume 236, Issue 03, Page(s) 189–192

Language	English
Publishing date	2024-01-30
Publisher	Georg Thieme Verlag
Publishing place	Stuttgart ; New York
Document type	Article
ZDB-ID	120650-3
ISSN	1439-3824 ; 0300-8630
ISSN (online)	1439-3824
ISSN	0300-8630
DOI	10.1055/a-2233-1021
Database	Thieme publisher's database

In stock of ZB MED Cologne/Königswinter

Um IV Zs.15: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Book ; Thesis: Analyse von Einflussfaktoren auf das Organ-/Patientenüberleben nach Kinderlebertransplantation

Herden, Uta

2014

Author's details	vorgelegt von Uta Herden
Language	German ; English
Size	getr. Zählung, Ill., graph. Darst.
Document type	Book ; Thesis
Thesis / German Habilitation thesis	Univ., FB Medizin, Habil.-Schr.--Hamburg, 2015
Note	Enth. zahlr. Zeitschriftenart. ; Text in dt. u. engl. Sprache
Database	Former special subject collection: coastal and deep sea fishing

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾

Article ; Online: Long-term Outcome of Pediatric Liver Transplant Recipients Who Have Reached Adulthood: A Single-center Experience.

Lund, Louisa Katharina / Grabhorn, Enke Freya / Rüther, Darius / Buchholz, Angela / Lang, Melanie / Herden, Uta / Fischer, Lutz / Sterneck, Martina

Transplantation

2023 Volume 107, Issue 8, Page(s) 1756–1763

Abstract: Background: As long-term survival of pediatric liver transplant recipients increases, the assessment of physical, psychological, and social well-being becomes more important.: Methods: In this retrospective analysis, 120 young adult patients (age ≥18 ...

Abstract	Background: As long-term survival of pediatric liver transplant recipients increases, the assessment of physical, psychological, and social well-being becomes more important. Methods: In this retrospective analysis, 120 young adult patients (age ≥18 y) who underwent liver transplantation in childhood were studied. Patients with ideal outcome were defined as patients with perfect graft function, with no complications from the immunosuppressive medication, no late retransplantation, and no steroid treatment. Also, the patients' drug adherence and their psychosocial situation were assessed. Results: After a median follow-up of 19 y, only 16.7% of the patients (mean age: 26.5 y) were considered patients with ideal outcome. The main reasons precluding ideal outcome were chronic kidney disease (38.3%), elevated liver enzymes (33.3%), and arterial hypertension (31.7%). Ideal outcome decreased over time from 54% to 42%, 26%, and 8% at 10-, 15-, 20-, and 25-y follow-up, respectively. Reduced drug adherence was noted in 24.8% of patients and associated with a significantly higher prevalence of donor-specific antibodies class II ( P = 0.015), elevated transaminases ( P = 0.010), and chronic rejection ( P < 0.001). Also, 15% of patients had a psychiatric disease, mainly depression. Conclusions: The morbidity of young adults who underwent liver transplantation as children was high and increased over time. The majority developed complications from immunosuppression or chronic graft dysfunction. More than 1 in 7 patients had a psychiatric disease and 1 in 4 was not perfectly drug adherent. Therefore, immunosuppressive treatment and psychological care should be optimized for these particularly vulnerable patients.
MeSH term(s)	Young Adult ; Child ; Humans ; Adult ; Liver Transplantation/adverse effects ; Retrospective Studies ; Immunosuppressive Agents/adverse effects ; Immunosuppression Therapy ; Liver Diseases ; Graft Rejection/epidemiology ; Graft Rejection/prevention & control ; Transplant Recipients ; Graft Survival
Chemical Substances	Immunosuppressive Agents
Language	English
Publishing date	2023-02-23
Publishing country	United States
Document type	Journal Article
ZDB-ID	208424-7
ISSN	1534-6080 ; 0041-1337
ISSN (online)	1534-6080
ISSN	0041-1337
DOI	10.1097/TP.0000000000004556
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 488: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 509: Show issues

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Protocol Biopsies in Pediatric Liver Transplantation Recipients Improve Graft Histology and Personalize Immunosuppression.

Karbaum, Eva / Weidemann, Sören / Grabhorn, Enke / Fischer, Lutz / Herden, Uta / Oh, Jun / Briem-Richter, Andrea / Krebs-Schmitt, Dorothee

Journal of pediatric gastroenterology and nutrition

2023 Volume 76, Issue 5, Page(s) 627–633

Abstract: Objectives: Protocol liver biopsies (PLBs) are part of the follow-up program at many pediatric liver transplant centers, but the impact on clinical decision-making and allograft histology following adjustments of immunosuppression (IS) after PLB has not ...

Abstract	Objectives: Protocol liver biopsies (PLBs) are part of the follow-up program at many pediatric liver transplant centers, but the impact on clinical decision-making and allograft histology following adjustments of immunosuppression (IS) after PLB has not been thoroughly analyzed. Methods: Following our previous single-center cohort study, we have now evaluated histological findings of 178 PLBs of 118 pediatric patients transplanted at our center between 1998 and 2017. In particular, we focused on the changes in allograft histology in the follow-up biopsy of a subgroup of 22 patients, in which the histologic findings led to an adjustment of immunosuppressive therapy. All biopsies of this sub-study group were reevaluated by an experienced pathologist. Results: The overall frequency and severity of fibrosis increased over time after orthotopic liver transplantation. Patients with donor-specific antibodies (DSAs) had a higher prevalence of fibrosis than DSA-negative patients. Graft inflammation decreased significantly after intensifying IS, but renal function needs to be monitored. A significant increase in fibrosis was detected in children with reduced IS. Conclusion: The adjustment of IS following PLBs has a significant impact on allograft histology. Since chronic inflammatory changes may lead to graft failure, adjustment of IS seems to be of major importance for the long-term outcome.
MeSH term(s)	Child ; Humans ; Liver Transplantation/methods ; Cohort Studies ; Graft Rejection/prevention & control ; Liver/pathology ; Fibrosis ; Immunosuppression Therapy ; Biopsy
Language	English
Publishing date	2023-01-24
Publishing country	United States
Document type	Journal Article
ZDB-ID	603201-1
ISSN	1536-4801 ; 0277-2116
ISSN (online)	1536-4801
ISSN	0277-2116
DOI	10.1097/MPG.0000000000003707
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 1728: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Impact of probe-induced abdominal compression on two-dimensional shear wave elastography measurement of split liver transplants in children.

Groth, Michael / Fischer, Lutz / Herden, Uta / Brinkert, Florian / Beime, Jan / Deindl, Philipp / Adam, Gerhard / Herrmann, Jochen

RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin

2023 Volume 195, Issue 10, Page(s) 905–912

Abstract: Purpose: To evaluate the effect of probe-induced abdominal compression of split liver transplants (SLT) in children on 2D-shear wave elastography (SWE) values.: Materials and methods: Data from 11 children (4.7 ± 4.8 years) who had undergone SLT and ... ...

Title translation	Der Einfluss der schallkopfinduzierten abdominellen Kompression auf die 2-dimensionale Scherwellen-Elastografie in Kindern mit Split-Leber-Transplantaten.
Abstract	Purpose: To evaluate the effect of probe-induced abdominal compression of split liver transplants (SLT) in children on 2D-shear wave elastography (SWE) values. Materials and methods: Data from 11 children (4.7 ± 4.8 years) who had undergone SLT and SWE were evaluated retrospectively. Elastograms were obtained with probes placed in an epigastric, midline position on the abdominal wall, with no and slight compression, using convex and linear transducers. For each identically positioned probe and condition, 12 serial elastograms were obtained and the SLT diameter was measured. Liver stiffness and degree of SLT compression were compared. Results: Slight probe pressure resulted in SLT compression, with a shorter distance between the cutis and the posterior margin of the liver transplant than in the measurement with no pressure (curved array, 5.0 ± 1.1 vs. 5.9 ± 1.3 cm, mean compression 15 %± 8 %; linear array, 4.7 ± 0.9 vs. 5.3 ± 1.0 cm, mean compression 12 %± 8 %; both p < 0.0001). The median liver stiffness was significantly greater with slight pressure than with no pressure (curved transducer, 13.38 ± 3.0 vs. 7.02 ± 1.7 kPa, p < 0.0001; linear transducer, 18.53 ± 7.1 vs. 9.03 ± 1.5 kPa, p = 0.0003). Conclusion: Slight abdominal compression can significantly increase SWE values in children with left-lateral SLT. To obtain meaningful results and reduce operator dependency in free-hand examinations, probe pressure must be controlled carefully. Key points: · Probe-induced compression can increase elastography values in split liver transplants in children. · In free-hand examination, probe pressure must be controlled carefully. · Pressure loading can be determined indirectly by the anteroposterior transplant diameter. Citation format: · Groth M, Fischer L, Herden U et al. Impact of probe-induced abdominal compression on two-dimensional shear wave elastography measurement of split liver transplants in children. Fortschr Röntgenstr 2023; 195: 905 - 912.
MeSH term(s)	Humans ; Child ; Liver Transplantation ; Elasticity Imaging Techniques/methods ; Retrospective Studies ; Pressure ; Liver/diagnostic imaging ; Liver/surgery ; Liver Cirrhosis
Language	English
Publishing date	2023-05-03
Publishing country	Germany
Document type	Journal Article
ZDB-ID	554830-5
ISSN	1438-9010 ; 0340-1618 ; 0936-6652 ; 1433-5972 ; 1438-9029
ISSN (online)	1438-9010
ISSN	0340-1618 ; 0936-6652 ; 1433-5972 ; 1438-9029
DOI	10.1055/a-2049-9369
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Ue I Zs.12: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Impact of donor-specific antibodies on long-term graft survival with pediatric liver transplantation.

Schotters, Felicitas Leonie / Beime, Jan / Briem-Richter, Andrea / Binder, Thomas / Herden, Uta / Grabhorn, Enke Freya

World journal of hepatology

2021 Volume 13, Issue 6, Page(s) 673–685

Abstract: Background: In a previous paper, we reported a high prevalence of donor-specific antibody (DSA) in pediatric patients with chronic rejection and expressed the need for confirmation of these findings in a larger cohort.: Aim: To clarify the importance ...

Abstract	Background: In a previous paper, we reported a high prevalence of donor-specific antibody (DSA) in pediatric patients with chronic rejection and expressed the need for confirmation of these findings in a larger cohort. Aim: To clarify the importance of DSAs on long-term graft survival in a larger cohort of pediatric patients. Methods: We performed a retrospective analysis of 123 pediatric liver transplantation (LT) recipients who participated in yearly follow-ups including Luminex testing for DSA at our center. The cohort was split into two groups according to the DSA status (DSA-positive Results: DSA-positive pediatric patients showed a higher prevalence of chronic rejection ( Conclusion: DSA prevalence significantly affected long-term liver allograft performance and liver allograft survival in our cohort of pediatric LT. Screening for class II DSAs in combination with assessment of protocol liver biopsies for chronic antibody-mediated rejection improved early identification of patients at risk of graft loss.
Language	English
Publishing date	2021-06-20
Publishing country	United States
Document type	Journal Article
ZDB-ID	2573703-X
ISSN	1948-5182
ISSN	1948-5182
DOI	10.4254/wjh.v13.i6.673
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: A single-center, open-label, randomized cross-over study to evaluate the pharmacokinetics and bioavailability of once-daily prolonged-release formulations of tacrolimus in de novo liver transplant recipients.

Herden, Uta / Sterneck, Martina / Buchholz, Bettina M / Achilles, Eike G / Ott, Armin / Fischer, Lutz

Immunity, inflammation and disease

2021 Volume 9, Issue 4, Page(s) 1771–1780

Abstract: Background: The narrow therapeutic window of tacrolimus (Tac) requires intense drug monitoring to achieve adequate efficacy while minimizing dose-related toxicities. Once-daily formulations of Tac (LCP-Tac and PR-Tac) have been recently designed for ... ...

Abstract	Background: The narrow therapeutic window of tacrolimus (Tac) requires intense drug monitoring to achieve adequate efficacy while minimizing dose-related toxicities. Once-daily formulations of Tac (LCP-Tac and PR-Tac) have been recently designed for higher bioavailability and a more consistent exposure over time, as opposed to the twice-daily, administered immediate-release formulation of Tac (IR-Tac). Methods: This single-center, open-label, randomized cross-over pharmacokinetic (PK) study compares extended-release LCP-Tac with the prolonged-release formulation of tacrolimus (PR-Tac) in adult de novo liver transplant recipients. Eligible patients were screened and randomized 1:1 to the two treatment arms up to 30 days after liver transplantation. Patients were administered either LCP-Tac or PR-Tac for 14 days followed by another 14-day time interval of the other once-daily Tac medication. A 24hr-PK profile was obtained at the end of each time interval. Results: Nine patients (45%) completed the study resulting in a total of 18 Tac PK profiles. Overall, the profile of the mean concentrations indicated a flattened kinetic of LCP-Tac compared to PR-Tac, especially in the first 3 h after drug intake. The average cumulative dose per day to achieve equivalent trough levels was approximately 25% lower for LCP-Tac (8.7 mg) than for PR-Tac (11.7 mg). LCP-Tac resulted in a longer t Conclusion: Despite methodological weaknesses that limit the conclusions, we have found a more consistent drug exposure for LCP-Tac in de novo LT recipients. LCP-Tac demonstrated a greater bioavailability compared to PR-Tac.
MeSH term(s)	Adult ; Biological Availability ; Cross-Over Studies ; Drug Administration Schedule ; Humans ; Immunosuppressive Agents ; Liver Transplantation ; Tacrolimus
Chemical Substances	Immunosuppressive Agents ; Tacrolimus (WM0HAQ4WNM)
Language	English
Publishing date	2021-09-24
Publishing country	England
Document type	Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
ZDB-ID	2740382-8
ISSN	2050-4527 ; 2050-4527
ISSN (online)	2050-4527
ISSN	2050-4527
DOI	10.1002/iid3.537
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

To top

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito