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  1. Book: Amyotrophe Lateralsklerose und andere Motoneuronerkrankungen

    Hermann, Andreas

    Pathophysiologie, Diagnostik und Therapie

    (Klinische Neurologie)

    2022  

    Abstract: In den letzten Jahren hat sich das Verständnis der ALS grundlegend revolutioniert. So handelt es sich um eine neuromuskuläre Multisystemerkrankung auf neurodegenerativer Grundlage, die ein Krankheitsspektrum mit den frontotemporalen Demenzen bildet. ... ...

    Author's details Andreas Hermann (Hrsg.)
    Series title Klinische Neurologie
    Abstract In den letzten Jahren hat sich das Verständnis der ALS grundlegend revolutioniert. So handelt es sich um eine neuromuskuläre Multisystemerkrankung auf neurodegenerativer Grundlage, die ein Krankheitsspektrum mit den frontotemporalen Demenzen bildet. Kognitive und Verhaltensstörungen sind heute fester Bestandteil der Diagnosekriterien, erste diagnostische Biomarker sind etabliert. Dies hat nicht nur erhebliche Konsequenzen für die Diagnostik, Behandlung und Versorgung der Patienten, sondern auch für das pathophysiologische Verständnis. Rasant zunehmende technische Entwicklungen, wie z. B. augensteuerungsbasierte Kommunikation, schaffen neuartige Möglichkeiten für Behandler, Patienten und deren Angehörige, die die Grenzentscheidungen für und gegen lebensverlängernde Maßnahmen zunehmend beeinflussen. Das Buch trägt diesen neuen Entwicklungen Rechnung und entwickelt neuartige Konzepte von der Grundlagenwissenschaft über Klassifikation und Diagnostik der Erkrankung bis hin zu Möglichkeiten und Grenzen aktueller und zukünftiger Therapieoptionen und Versorgungskonzepten.
    Keywords ALS ; Gentechnologie ; Gesundheitsversorgung ; Neurowissenschaften ; Palliativ ; Myatrophische Lateralsklerose ; Motoneuron ; Krankheit
    Subject Erkrankung ; Krankheitszustand ; Krankheiten ; Morbus ; Nosos ; Pathos ; Motorisches Neuron ; Amyotrophe Lateralsklerose ; Amyotrophe Seitenstrangsklerose ; Amyotrophische Lateralsklerose ; Amyotrophische Seitenstrangsklerose ; MALS ; ALS
    Language German
    Size 158 Seiten, Illustrationen
    Edition 1. Auflage
    Publisher Kohlhammer
    Publishing place Stuttgart
    Publishing country Germany
    Document type Book
    HBZ-ID HT021493555
    ISBN 978-3-17-039166-6 ; 3-17-039166-6 ; 9783170391673 ; 9783170391680 ; 3170391674 ; 3170391682
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2022 A 1155 available for loan (reading room) Lesesaal EG

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  2. Book ; Online: First-Principles Prediction of Structures and Properties in Crystals

    Hermann, Andreas / Kurzydlowski, Dominik

    2019  

    Abstract: The term "first-principles calculations" is a synonym for the numerical determination of the electronic structure of atoms, molecules, clusters, or materials from 'first principles', i.e., without any approximations to the underlying quantum-mechanical ... ...

    Abstract The term "first-principles calculations" is a synonym for the numerical determination of the electronic structure of atoms, molecules, clusters, or materials from 'first principles', i.e., without any approximations to the underlying quantum-mechanical equations. Although numerous approximate approaches have been developed for small molecular systems since the late 1920s, it was not until the advent of the density functional theory (DFT) in the 1960s that accurate "first-principles" calculations could be conducted for crystalline materials. The rapid development of this method over the past two decades allowed it to evolve from an explanatory to a truly predictive tool. Yet, challenges remain: complex chemical compositions, variable external conditions (such as pressure), defects, or properties that rely on collective excitations-all represent computational and/or methodological bottlenecks. This Special Issue comprises a collection of papers that use DFT to tackle some of these challenges and thus highlight what can (and cannot yet) be achieved using first-principles calculations of crystals
    Keywords Science (General) ; Chemistry ; Physical and theoretical chemistry
    Size 1 electronic resource (128 pages)
    Publisher MDPI - Multidisciplinary Digital Publishing Institute
    Document type Book ; Online
    Note eng ; Open Access
    HBZ-ID HT020324157
    ISBN 9783039216703 ; 9783039216710 ; 3039216708 ; 3039216716
    DOI 10.3390/books978-3-03921-671-0
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Book ; Thesis: Der Palmomentalreflex bei der Amyotrophen Lateralsklerose

    Vidović, Maximilian Reinhold Johann / Hermann, Andreas / Donix, Markus

    Zeichen einer kognitiven oder motoneuronalen Dysfunktion?

    2022  

    Institution Klinik und Poliklinik für Neurologie
    Author's details von Maximilian Reinhold Johann Vidović aus Frankfurt am Main ; Klinik und Poliklinik für Neurologie [Dresden]
    Language German
    Size V, 98 Seiten, Illustrationen, Diagramme
    Publishing place Dresden
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Technische Universität Dresden, Medizinische Fakultät, 2022
    HBZ-ID HT030629972
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2024 E 141 order for loan Magazin

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  4. Book ; Online: Assessment of impacts of a European register of products containing nanomaterials

    Hermann, Andreas / Schwirn, Kathrin

    (Texte / Umweltbundesamt ; 2014,23 ; UBA-FB ; 1907/E ; Environmental research of the Federal Ministry of the Environment, Nature Conservation, Building and Nuclear Safety)

    2014  

    Author's details by Andreas Hermann ... [ed. by Section IV 2.2 Pharmaceuticals, Washing and Cleaning Agents, Kathrin Schwirn]
    Series title Texte / Umweltbundesamt ; 2014,23
    UBA-FB ; 1907/E
    Environmental research of the Federal Ministry of the Environment, Nature Conservation, Building and Nuclear Safety
    Collection
    Subject code 610
    Language English
    Size 139 S.
    Publisher Umweltbundesamt
    Publishing place Dessau-Roßlau
    Publishing country Germany
    Document type Book ; Online
    Note Zsfassung in dt. Sprache
    HBZ-ID HT018203097
    DOI 10.4126/38m-005541885
    Database Repository for Life Sciences

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  5. Book ; Online: Verantwortungsvoller Umgang mit neuen gentechnischen Verfahren

    Möller, Martin / Hermann, Andreas / Köhler, Andreas R. / Moch, Katja

    Positionspapier zu den Chancen und Risiken der Anwendung von "Genome Editing" in der Landwirtschaft

    2018  

    Institution Öko-Institut
    Author's details Öko-Insititut e.V. ; Ansprechpartner am Öko-Institut: Dipl.-Ing. Martin Möller, Andreas Hermann LL.M.; weitere Autoren und Autorinnen: Dr. Andreas Köhler, Dipl.-Biol. Katja Moch
    Subject code 630
    Language German
    Size 1 Online-Ressource (6 Seiten)
    Publisher Öko-Institut e.V.
    Publishing place Freiburg ; Darmstadt
    Publishing country Germany
    Document type Book ; Online
    Remark Elektronischer Volltext
    HBZ-ID HT019770865
    DOI 10.4126/FRL01-006409259
    Database Repository for Life Sciences

    Full text online

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  6. Book ; Online: Verantwortungsvoller Umgang mit neuen gentechnischen Verfahren

    Möller, Martin / Hermann, Andreas / Köhler, Andreas R. / Moch, Katja

    Positionspapier zu den Chancen und Risiken der Anwendung von "Genome Editing" in der Landwirtschaft

    2018  

    Institution Öko-Institut
    Author's details Öko-Insititut e.V. ; Ansprechpartner am Öko-Institut: Dipl.-Ing. Martin Möller, Andreas Hermann LL.M.; weitere Autoren und Autorinnen: Dr. Andreas Köhler, Dipl.-Biol. Katja Moch
    Subject code 630
    Language German
    Size 1 Online-Ressource (6 Seiten)
    Publisher Öko-Institut e.V.
    Publishing place Freiburg ; Darmstadt
    Publishing country Germany
    Document type Book ; Online
    Remark Elektronischer Volltext
    HBZ-ID HT019770865
    DOI 10.4126/FRL01-006409259
    Database Repository for Life Sciences

    Full text online

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    Inter-library loan at ZB MED

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  7. Article: Combination of novel RNA sequencing and sophisticated network modeling to reveal a common denominator in amyotrophic lateral sclerosis?

    Dash, Banaja P / Hermann, Andreas

    Neural regeneration research

    2023  Volume 18, Issue 11, Page(s) 2403–2405

    Language English
    Publishing date 2023-06-06
    Publishing country India
    Document type Journal Article
    ZDB-ID 2388460-5
    ISSN 1876-7958 ; 1673-5374
    ISSN (online) 1876-7958
    ISSN 1673-5374
    DOI 10.4103/1673-5374.371364
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Increased Vulnerability to Ferroptosis in FUS-ALS.

    Ismail, Muhammad / Großmann, Dajana / Hermann, Andreas

    Biology

    2024  Volume 13, Issue 4

    Abstract: Ferroptosis, a regulated form of cell death characterized by iron-dependent lipid peroxide accumulation, plays a pivotal role in various pathological conditions, including neurodegenerative diseases. While reasonable evidence for ferroptosis exists, e.g., ...

    Abstract Ferroptosis, a regulated form of cell death characterized by iron-dependent lipid peroxide accumulation, plays a pivotal role in various pathological conditions, including neurodegenerative diseases. While reasonable evidence for ferroptosis exists, e.g., in Parkinson's disease or Alzheimer's disease, there are only a few reports on amyotrophic lateral sclerosis (ALS), a fast progressive and incurable neurodegenerative disease characterized by progressive motor neuron degeneration. Interestingly, initial studies have suggested that ferroptosis might be significantly involved in ALS. Key features of ferroptosis include oxidative stress, glutathione depletion, and alterations in mitochondrial morphology and function, mediated by proteins such as GPX4, xCT, ACSL4 FSP1, Nrf2, and TfR1. Induction of ferroptosis involves small molecule compounds like erastin and RSL3, which disrupt system Xc
    Language English
    Publishing date 2024-03-26
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2661517-4
    ISSN 2079-7737
    ISSN 2079-7737
    DOI 10.3390/biology13040215
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Book ; Thesis: Registrierung porciner CT- und EIT-Thoraxaufnahmen und Verifikation elastischer Registrierungsverfahren zur Atemlagenkorrektur in pulmonalen CT-Aufnahmen mittels intrinsischer Landmarken

    Prüm, Hermann

    2013  

    Author's details vorgelegt von Hermann Prüm
    Language German
    Size IV, 131 Bl. : Ill., graph. Darst.
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Heidelberg, Univ., Diss., 2014
    HBZ-ID HT018673173
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2015 E 927 order for loan Magazin

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  10. Book: Spinale Muskelatrophie

    Kleinschnitz, Christoph / Hagenacker, Tim / Hermann, Andreas / Günther, René / Kamm, Christoph / Walter, Maggie C. / Weiler, Markus / Wurster, Claudia

    Expertenempfehlungen zur Behandlung von erwachsenen Patienten mit Nusinersen

    (Therapie Report spezial ; 7. Jahrgang, Heft 1 (September 2019))

    2019  

    Author's details Herausgeber [und Autoren] Prof. Dr. Christoph Kleinschnitz. Autoren: Priv.-Doz. Dr. med. Tim Hagenacker, Prof. Dr. med. Dr. rer. med. Andreas Hermann, Dr. med. René Günther, Priv.-Doz. Dr. med. Christoph Kamm, Prof. Dr. med. Maggie C. Walter, Priv.-Doz. Dr. med. Markus Weiler, Dr. med. Claudia Wurster
    Series title Therapie Report spezial ; 7. Jahrgang, Heft 1 (September 2019)
    Therapie Report Spezial
    Collection Therapie Report Spezial
    Language German
    Size 11 Seiten, Illustrationen, Diagramme
    Publisher Thieme
    Publishing place Stuttgart
    Publishing country Germany
    Document type Book
    HBZ-ID HT020360318
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Zs A 7165 -7,1- verfügbar in Königswinter Königswinter

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