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  1. Article ; Online: Importance of Comprehensive Transesophageal Echocardiography Examination in a Patient With Infective Endocarditis of the Mitral Valve.

    Fraessdorf, Jan / Klautz, Robert J M / Hermanns, Henning

    Journal of cardiothoracic and vascular anesthesia

    2023  Volume 37, Issue 12, Page(s) 2597–2599

    MeSH term(s) Humans ; Mitral Valve/diagnostic imaging ; Mitral Valve/surgery ; Echocardiography, Transesophageal ; Endocarditis, Bacterial/complications ; Endocarditis, Bacterial/diagnostic imaging ; Endocarditis, Bacterial/surgery ; Endocarditis/complications ; Endocarditis/diagnostic imaging
    Language English
    Publishing date 2023-09-09
    Publishing country United States
    Document type Case Reports
    ZDB-ID 1067317-9
    ISSN 1532-8422 ; 1053-0770
    ISSN (online) 1532-8422
    ISSN 1053-0770
    DOI 10.1053/j.jvca.2023.09.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Perioperative Complications in Infective Endocarditis.

    Hermanns, Henning / Alberts, Tim / Preckel, Benedikt / Strypet, Magnus / Eberl, Susanne

    Journal of clinical medicine

    2023  Volume 12, Issue 17

    Abstract: Infective endocarditis is a challenging condition to manage, requiring collaboration among various medical professionals. Interdisciplinary teamwork within endocarditis teams is essential. About half of the patients diagnosed with the disease will ... ...

    Abstract Infective endocarditis is a challenging condition to manage, requiring collaboration among various medical professionals. Interdisciplinary teamwork within endocarditis teams is essential. About half of the patients diagnosed with the disease will ultimately have to undergo cardiac surgery. As a result, it is vital for all healthcare providers involved in the perioperative period to have a comprehensive understanding of the unique features of infective endocarditis, including clinical presentation, echocardiographic signs, coagulopathy, bleeding control, and treatment of possible organ dysfunction. This narrative review provides a summary of the current knowledge on the incidence of complications and their management in the perioperative period in patients with infective endocarditis.
    Language English
    Publishing date 2023-09-04
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12175762
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Evaluation of Health Care Providers Satisfaction with the Implementation of a Transitional Pain Service.

    Admiraal, Manouk / Hermanides, Jeroen / Hollmann, Markus W / Hermanns, Henning

    Journal of clinical medicine

    2023  Volume 12, Issue 2

    Abstract: Chronic postsurgical pain develops in 10% of patients undergoing surgery. Recently, multidisciplinary, patient-tailored interventions, such as a Transitional Pain Service (TPS) have been developed and implemented to improve perioperative pain management ... ...

    Abstract Chronic postsurgical pain develops in 10% of patients undergoing surgery. Recently, multidisciplinary, patient-tailored interventions, such as a Transitional Pain Service (TPS) have been developed and implemented to improve perioperative pain management and thereby prevent chronic postsurgical pain. The purpose of this survey was to analyse health care providers satisfaction and learn from their experiences on the implementation of a TPS. In the TRUST study, a randomized controlled trial investigating the effectiveness of a TPS, 176 patients were enrolled. Afterwards, a satisfaction survey was internally developed, which consisted of eight items. Satisfaction was measured using a Likert scale with five response options from never (1 point) to always (5 points). Surveys were sent to all anaesthetists and anaesthesia residents in our department that were faced with the consequences of TPS implementation. In May 2022, 36 caregivers of the Department of Anaesthesiology returned the survey after four rounds of distribution, with a response rate of 82.3%. Thirty staff members (81.0%) strongly felt that patient care had improved with the introduction of a TPS and 33 (86.8%) would like to see the TPS to be continued in the future. Health care provider satisfaction improved after implementation of a TPS in our hospital.
    Language English
    Publishing date 2023-01-09
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12020537
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Differences in the Incidence of Hypotension and Hypertension between Sexes during Non-Cardiac Surgery: A Systematic Review and Meta-Analysis.

    Bos, Elke M E / Tol, Johan T M / de Boer, Fabienne C / Schenk, Jimmy / Hermanns, Henning / Eberl, Susanne / Veelo, Denise P

    Journal of clinical medicine

    2024  Volume 13, Issue 3

    Abstract: ... ...

    Abstract Background
    Language English
    Publishing date 2024-01-24
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm13030666
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Cerebral Glucose Metabolism following TBI: Changes in Plasma Glucose, Glucose Transport and Alternative Pathways of Glycolysis-A Translational Narrative Review.

    Gribnau, Annerixt / van Zuylen, Mark L / Coles, Jonathan P / Plummer, Mark P / Hermanns, Henning / Hermanides, Jeroen

    International journal of molecular sciences

    2024  Volume 25, Issue 5

    Abstract: Traumatic brain injury (TBI) is a major public health concern with significant consequences across various domains. Following the primary event, secondary injuries compound the outcome after TBI, with disrupted glucose metabolism emerging as a relevant ... ...

    Abstract Traumatic brain injury (TBI) is a major public health concern with significant consequences across various domains. Following the primary event, secondary injuries compound the outcome after TBI, with disrupted glucose metabolism emerging as a relevant factor. This narrative review summarises the existing literature on post-TBI alterations in glucose metabolism. After TBI, the brain undergoes dynamic changes in brain glucose transport, including alterations in glucose transporters and kinetics, and disruptions in the blood-brain barrier (BBB). In addition, cerebral glucose metabolism transitions from a phase of hyperglycolysis to hypometabolism, with upregulation of alternative pathways of glycolysis. Future research should further explore optimal, and possibly personalised, glycaemic control targets in TBI patients, with GLP-1 analogues as promising therapeutic candidates. Furthermore, a more fundamental understanding of alterations in the activation of various pathways, such as the polyol and lactate pathway, could hold the key to improving outcomes following TBI.
    MeSH term(s) Humans ; Brain Injuries/metabolism ; Blood Glucose ; Glucose/metabolism ; Brain Injuries, Traumatic/metabolism ; Glycolysis
    Chemical Substances Blood Glucose ; Glucose (IY9XDZ35W2)
    Language English
    Publishing date 2024-02-21
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms25052513
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Reply.

    Hermanns, Henning / Kaya, Abdullah

    The Annals of thoracic surgery

    2018  Volume 107, Issue 4, Page(s) 1289–1290

    MeSH term(s) Endocarditis ; Humans ; Mitral Valve
    Language English
    Publishing date 2018-12-23
    Publishing country Netherlands
    Document type Letter ; Comment
    ZDB-ID 211007-6
    ISSN 1552-6259 ; 0003-4975
    ISSN (online) 1552-6259
    ISSN 0003-4975
    DOI 10.1016/j.athoracsur.2018.11.056
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: The Options for Neuraxial Drug Administration.

    Hermanns, Henning / Bos, Elke M E / van Zuylen, Mark L / Hollmann, Markus W / Stevens, Markus F

    CNS drugs

    2022  Volume 36, Issue 8, Page(s) 877–896

    Abstract: Neuraxial drug administration, i.e., the injection of drugs into the epidural or intrathecal space to produce anesthesia or analgesia, is a technique developed more than 120 years ago. Today, it still is widely used in daily practice in anesthesiology ... ...

    Abstract Neuraxial drug administration, i.e., the injection of drugs into the epidural or intrathecal space to produce anesthesia or analgesia, is a technique developed more than 120 years ago. Today, it still is widely used in daily practice in anesthesiology and in acute and chronic pain therapy. A multitude of different drugs have been introduced for neuraxial injection, only a part of which have obtained official approval for that indication. A broad understanding of the pharmacology of those agents is essential to the clinician to utilize them in a safe and efficient manner. In the present narrative review, we summarize current knowledge on neuraxial anatomy relevant to clinical practice, including pediatric anatomy. Then, we delineate the general pharmacology of neuraxial drug administration, with particular attention to specific aspects of epidural and intrathecal pharmacokinetics and pharmacodynamics. Furthermore, we describe the most common clinical indications for neuraxial drug administration, including the perioperative setting, obstetrics, and chronic pain. Then, we discuss possible neurotoxic effects of neuraxial drugs, and moreover, we detail the specific properties of the most commonly used neuraxial drugs that are relevant to clinicians who employ epidural or intrathecal drug administration, in order to ensure adequate treatment and patient safety in these techniques. Finally, we give a brief overview on new developments in neuraxial drug therapy.
    MeSH term(s) Analgesia, Epidural/methods ; Central Nervous System ; Child ; Chronic Pain/drug therapy ; Female ; Humans ; Injections ; Pain Management ; Pregnancy
    Language English
    Publishing date 2022-07-15
    Publishing country New Zealand
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 1203800-3
    ISSN 1179-1934 ; 1172-7047
    ISSN (online) 1179-1934
    ISSN 1172-7047
    DOI 10.1007/s40263-022-00936-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: What Really Matters to Survivors of Acute Type A Aortic Dissection-A Survey of Patient-Reported Outcomes in the Dutch National Aortic Dissection Advocacy Group.

    Breel, Jennifer S / de Klerk, Eline S / Strypet, Magnus / de Heer, Frederiek / Hermanns, Henning / Hollmann, Markus W / Eberl, Susanne

    Journal of clinical medicine

    2023  Volume 12, Issue 20

    Abstract: 1) Background: Type A acute aortic dissection (TAAAD) almost always requires emergency surgery, and postoperative complications are common. Quality assurance systems tend to measure only the hard outcomes, e.g., complications and mortality. Our aim was ... ...

    Abstract (1) Background: Type A acute aortic dissection (TAAAD) almost always requires emergency surgery, and postoperative complications are common. Quality assurance systems tend to measure only the hard outcomes, e.g., complications and mortality. Our aim was to assess the health-related quality of life of TAAAD survivors. (2) Methods: An anonymized, Dutch language, web-based survey was sent out to all of the participants of the 2022 Annual Meeting of the Dutch National Aortic Dissection (DNAD) advocacy group via their own representatives. The survey was divided into five sections: patient information, global satisfaction, surgery, including complications, and the recovery period. (3) Results: Ninety members of the DNAD group attended the meeting. Seventy-five (83%) participated in the survey, and the responses from 61 (81%) were available for analysis. Despite hindrances in their daily life (complications, changes in physical, cognitive, and social functioning), patients were satisfied with their treatment, and all would undergo the procedure again. In addition they requested better post-discharge guidance and communication (4) Conclusion: The emphasis lies in equipping patients with knowledge about potential outcomes and effective coping strategies. This underscores the importance of communication and expectation management, in line with established literature.
    Language English
    Publishing date 2023-10-18
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12206584
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  9. Article: Comparison of Patient-Controlled versus Continuous Epidural Analgesia in Adult Surgical Patients: A Systematic Review.

    van Samkar, Ganapathy / Ru Tan, Yan / Hermanns, Henning / Preckel, Benedikt / Jamaludin, Faridi S / Hollmann, Markus W / Stevens, Markus F

    Journal of clinical medicine

    2023  Volume 12, Issue 9

    Abstract: Background: The advantages of PCEA over CEA have been demonstrated in obstetric patients. Whether a similar benefit applies to surgical patients is unclear.: Methods: Embase, PubMed, and Cochrane Library were searched, enabling a systematic review of ...

    Abstract Background: The advantages of PCEA over CEA have been demonstrated in obstetric patients. Whether a similar benefit applies to surgical patients is unclear.
    Methods: Embase, PubMed, and Cochrane Library were searched, enabling a systematic review of studies comparing PCEA and CEA in adult surgical patients (PROSPERO: CRD42018106644). The study quality was assessed using the Cochrane risk-of-bias tool (RoB2). The primary outcome was pain scores on postoperative day one (POD1). Secondary outcomes were 24 or 48 h epidural or intravenous total analgesic dose, systemic analgesics, manual top-ups, side effects, and patient satisfaction.
    Results: Six randomized controlled trials with high heterogeneity of study characteristics were identified with a moderate risk of bias. Two studies showed significantly reduced resting pain scores on POD1 in PCEA compared with CEA patients (36-44%,
    Conclusions: Regarding the reduction in pain scores, the effects of PCEA were not significant or clinically not relevant. However, regarding the amount of epidural drug use, the amount of required rescue systemic analgesics, patient satisfaction, and the number of required top-ups, PCEA had advantages over CEA in surgical patients.
    Language English
    Publishing date 2023-04-27
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12093164
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  10. Article ; Online: International Survey on Perioperative Management of Patients With Infective Endocarditis.

    Breel, Jennifer S / Eberl, Susanne / Preckel, Benedikt / Huhn, Ragnar / Hollmann, Markus W / Rex, Steffen / Hermanns, Henning

    Journal of cardiothoracic and vascular anesthesia

    2023  Volume 37, Issue 10, Page(s) 1951–1958

    Abstract: Objectives: To estimate the current practice in the perioperative management of patients undergoing cardiac surgery due to infective endocarditis.: Design: A prospective, open, 24-item, web-based cross-sectional survey.: Setting: Online survey ... ...

    Abstract Objectives: To estimate the current practice in the perioperative management of patients undergoing cardiac surgery due to infective endocarditis.
    Design: A prospective, open, 24-item, web-based cross-sectional survey.
    Setting: Online survey endorsed by the European Association of Cardiothoracic Anesthesiology and Intensive Care (EACTAIC).
    Participants: Members of the EACTAIC.
    Interventions: None.
    Measurements and main results: A total of 156 responses from 44 countries were received, with a completion rate of 99%. The response rate was 16.6%. Most respondents (76%) practiced cardiac anesthesia in European hospitals, and most respondents stated that a multidisciplinary endocarditis team was not established at their center, that cardiac anesthesiologists appeared to be involved infrequently in those teams (36%), and that they were not involved in decision-making on indication and timing of surgery (88%). In contrast, the cardiac anesthesiologist performed intraoperative antibiotic therapy (62%) and intraoperative transesophageal echocardiography (90%). Furthermore, there was a relative heterogeneity concerning perioperative monitoring, as well as for coagulation and transfusion management.
    Conclusions: This international survey evaluated current practice among cardiac anesthesiologists in the perioperative management of patients with infective endocarditis and the anesthesiologist's role in multidisciplinary decision-making. Heterogeneity in treatment approaches was identified, indicating relevant knowledge gaps that should encourage further clinical research to optimize treatment and postoperative outcomes in this specific population.
    MeSH term(s) Humans ; Cross-Sectional Studies ; Prospective Studies ; Cardiac Surgical Procedures ; Surveys and Questionnaires ; Endocarditis/surgery
    Language English
    Publishing date 2023-06-14
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1067317-9
    ISSN 1532-8422 ; 1053-0770
    ISSN (online) 1532-8422
    ISSN 1053-0770
    DOI 10.1053/j.jvca.2023.06.019
    Database MEDical Literature Analysis and Retrieval System OnLINE

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