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  1. AU="Hermans, Philippe"
  2. AU="Jayaprakash Nattamai Subramanian"
  3. AU="Thorstensen, Matt J"
  4. AU="Konishi, Teruaki"
  5. AU="Jiang, Haiyue"
  6. AU="Kuznetsov, N S"
  7. AU=Rimmer Abi AU=Rimmer Abi
  8. AU="Zhou, Qinyao"
  9. AU="Taniguchi, Ryou"
  10. AU="Krauss, Thomas F"
  11. AU="Papoulidis, Ioannis"
  12. AU="Migaud, Henri"
  13. AU="Kelion, Andrew"
  14. AU="Harry Jabs"
  15. AU="Patel, Yatindra"
  16. AU="Aziza Jamal-Allial"
  17. AU="Montiel, Olga Martha"
  18. AU="Pérez Latorre, Leire"
  19. AU=Vardhan Seshu
  20. AU="OJ Baker"
  21. AU="Dalton, R C"
  22. AU="Mrozikiewicz-Rakowska, Beata"
  23. AU="Penkert, Judith"
  24. AU="Mak, Susanna"
  25. AU="Karkoszka, Henryk"
  26. AU="Burton, Jeffrey H"
  27. AU="Frederique Pitel"
  28. AU="Pierce, Aimee"
  29. AU="Luque-Ballesteros, Laura"
  30. AU="Dondi, Francesco"
  31. AU="McLachlan, Alex"
  32. AU="Krizova, Ludmila"
  33. AU="Balog, Attila"
  34. AU="Faerber, Karin"
  35. AU="Prettner, Klaus"
  36. AU="Ambrožová, I."
  37. AU="William, Doreen"
  38. AU="Gutiérrez-Sánchez, A M"
  39. AU="Bohan, Dana"
  40. AU="Spracklen, D."
  41. AU="Lobo, Brian C"
  42. AU=Zhuang Jianjian AU=Zhuang Jianjian
  43. AU=Pathanki Adithya M
  44. AU="Armando Vilchis-Ordoñez"
  45. AU="Zhongfu Lu"
  46. AU="Lo, Hong-Yip"
  47. AU="Ziman Xiong"
  48. AU="Oakes, Allison H"
  49. AU="Ma, Shaotong"
  50. AU="Zang, Lili"
  51. AU="Adams Brian D"
  52. AU="Maria Papaioannou"
  53. AU="Kollia, Georgia"
  54. AU="Auxiette, Catherine"
  55. AU="Guzmán, Luis"
  56. AU="Alipour, Elnaz"
  57. AU="Queiroz, Dayanna Joyce Marques"
  58. AU="Ramamurthy, Santosh"
  59. AU="Xueying Huang"
  60. AU="Cromwell, Howard C"
  61. AU="Spence, John C H"
  62. AU="Chapinal, Libertad"
  63. AU=Rohaim Mohammed A AU=Rohaim Mohammed A
  64. AU=Hempel Cornelius

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  1. Buch: De wereld van de djinn

    Hermans, Philippe

    traditionele geneeswijzen in Marokko

    2007  

    Verfasserangabe Philip Hermans
    Mesh-Begriff(e) Medicine, Traditional
    Schlagwörter Morocco
    Sprache Niederländisch
    Umfang 207 p. :, ill.
    Verlag Bulaaq
    Erscheinungsort Amsterdam
    Dokumenttyp Buch
    ISBN 9789054601425 ; 9054601426
    Datenquelle Katalog der US National Library of Medicine (NLM)

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  2. Artikel ; Online: Management and Prevention of Percutaneous Iliac Stent Infection: A Case Report.

    Wissanji, Tahir / Fouard, Olivier / Herman, Dominique / Hermans, Philippe / Vindevogel, Christophe

    Annals of vascular surgery

    2016  Band 32, Seite(n) 131.e1–5

    Abstract: A 52-year-old man was admitted in the emergency department for deteriorating mental status and suspicion of discitis. Computed tomography and positron emission tomography scan showed evidence of localized infection of the aortic bifurcation and blood ... ...

    Abstract A 52-year-old man was admitted in the emergency department for deteriorating mental status and suspicion of discitis. Computed tomography and positron emission tomography scan showed evidence of localized infection of the aortic bifurcation and blood cultures were positive for Staphylococcus aureus. Ten years ago, the patient underwent placement of covered metal stents on each common iliac artery due to arteritic stenosis. The infected material was removed and aortic bifurcation repaired using an autologous femoral vein graft. This case report describes the surgical procedure, patient outcome, and review on prevention of such complications.
    Mesh-Begriff(e) Computed Tomography Angiography ; Device Removal ; Endovascular Procedures/adverse effects ; Endovascular Procedures/instrumentation ; Femoral Vein/transplantation ; Humans ; Iliac Artery/diagnostic imaging ; Iliac Artery/microbiology ; Iliac Artery/surgery ; Male ; Metals ; Middle Aged ; Prosthesis Design ; Prosthesis-Related Infections/diagnosis ; Prosthesis-Related Infections/microbiology ; Prosthesis-Related Infections/surgery ; Staphylococcal Infections/diagnosis ; Staphylococcal Infections/microbiology ; Staphylococcal Infections/surgery ; Staphylococcus aureus/isolation & purification ; Stents/adverse effects ; Time Factors ; Transplantation, Autologous ; Treatment Outcome
    Chemische Substanzen Metals
    Sprache Englisch
    Erscheinungsdatum 2016-04
    Erscheinungsland Netherlands
    Dokumenttyp Case Reports ; Journal Article ; Review
    ZDB-ID 1027366-9
    ISSN 1615-5947 ; 0890-5096
    ISSN (online) 1615-5947
    ISSN 0890-5096
    DOI 10.1016/j.avsg.2015.10.031
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel: Plasmablastic microlymphoma occurring in human herpesvirus 8 (HHV-8)-positive multicentric Castleman's disease and featuring a follicular growth pattern.

    Dargent, Jean-Louis / Lespagnard, Laurence / Sirtaine, Nicolas / Cantinieaux, Brigitte / Li, Rong / Hermans, Philippe

    APMIS : acta pathologica, microbiologica, et immunologica Scandinavica

    2007  Band 115, Heft 7, Seite(n) 869–874

    Abstract: Plasmablastic microlymphoma (PML) is defined as the accumulation of monotypic but polyclonal plasmablasts in lymphoid tissues involved in human herpes virus 8 (HHV-8)-positive multicentric Castleman's disease (MCD). So far, the nature of this very rare ... ...

    Abstract Plasmablastic microlymphoma (PML) is defined as the accumulation of monotypic but polyclonal plasmablasts in lymphoid tissues involved in human herpes virus 8 (HHV-8)-positive multicentric Castleman's disease (MCD). So far, the nature of this very rare condition remains poorly determined. In this study, we describe a human immunodeficiency virus (HIV)-seropositive patient who developed a PML in the setting of HHV-8-positive MCD. In contrast to the cases previously reported, most of the plasmablasts in our patient were localized within the germinal center (GC) of lymphoid follicles. These plasmablasts expressed the multiple myeloma-1/interferon regulatory factor-4 (MUM1/IRF4) protein as well as IgMlambda in a monotypic fashion. They did not show any immunoreactivity with antibodies directed against Pax-5, CD20, CD79a, CD10, CD30, CD23, CD138, epithelial membrane antigen (EMA) or BCL-6. These cells exhibited a high proliferation rate, expressed the HHV-8 latent nuclear antigen-1, and secreted the HHV-8 viral homologue of human interleukin-6. Polymerase chain reaction analysis did not demonstrate any clonal rearrangement of the genes coding for the heavy chain of the immunoglobulin. Moreover, no Epstein-Barr virus (EBV) RNA transcript could be found, using in situ hybridization. The present case illustrates that PML may arise within the GC of lymphoid follicles in the absence of EBV coinfection. In our opinion, PML occurring in MCD likely represents a variant of HHV-8-positive MCD in which lytic HHV-8 replication is particularly prominent, due to a local or systemic immune imbalance.
    Mesh-Begriff(e) Adult ; Biomarkers, Tumor/analysis ; Castleman Disease/complications ; Castleman Disease/virology ; Fatal Outcome ; HIV Seropositivity/complications ; Herpesvirus 8, Human/isolation & purification ; Humans ; Lymph Nodes/pathology ; Lymphoma, B-Cell/diagnosis ; Lymphoma, B-Cell/pathology ; Lymphoma, B-Cell/virology
    Chemische Substanzen Biomarkers, Tumor
    Sprache Englisch
    Erscheinungsdatum 2007-07
    Erscheinungsland Denmark
    Dokumenttyp Case Reports ; Journal Article
    ZDB-ID 93340-5
    ISSN 1600-0463 ; 0903-4641
    ISSN (online) 1600-0463
    ISSN 0903-4641
    DOI 10.1111/j.1600-0463.2007.apm_631.x
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel: Delayed HIV primary infection diagnosis with a fourth-generation HIV assay.

    Delforge, Marie-Luce / Dollé, Nicole / Hermans, Philippe / Liesnard, Corinne

    AIDS (London, England)

    2002  Band 16, Heft 1, Seite(n) 128–130

    Mesh-Begriff(e) AIDS Serodiagnosis ; Adult ; HIV Antibodies/blood ; HIV Core Protein p24/blood ; HIV Infections/diagnosis ; HIV Infections/virology ; Humans ; Male ; Reagent Kits, Diagnostic
    Chemische Substanzen HIV Antibodies ; HIV Core Protein p24 ; Reagent Kits, Diagnostic
    Sprache Englisch
    Erscheinungsdatum 2002-01-04
    Erscheinungsland England
    Dokumenttyp Case Reports ; Evaluation Studies ; Letter
    ZDB-ID 639076-6
    ISSN 1473-5571 ; 0269-9370 ; 1350-2840
    ISSN (online) 1473-5571
    ISSN 0269-9370 ; 1350-2840
    DOI 10.1097/00002030-200201040-00018
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: Neutralizing anti-Tat antibodies prolonged HAART interruption in vaccines in a prospective structured interruption study

    Redfield Robert / Gilliam Bruce / Bizzini Bernard / Burny Arsène / Buanec Hélène Le / Zagury Daniel / Hermans Philippe / Clumeck Nathan / Gallo Robert

    Retrovirology, Vol 3, Iss Suppl 1, p S

    2006  Band 15

    Schlagwörter Medicine (General) ; R5-920 ; Medicine ; R ; DOAJ:Medicine (General) ; DOAJ:Health Sciences ; Immunologic diseases. Allergy ; RC581-607
    Sprache Englisch
    Erscheinungsdatum 2006-12-01T00:00:00Z
    Verlag BioMed Central
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  6. Artikel ; Online: Effect of N-acetylcysteine on pain in daily life in patients with sickle cell disease: a randomised clinical trial.

    Sins, Joep W R / Fijnvandraat, Karin / Rijneveld, Anita W / Boom, Martine B / Kerkhoffs, Jean-Louis H / van Meurs, Alfred H / de Groot, Marco R / Heijboer, Harriët / Dresse, Marie-Françoise / Lê, Phu Quoc / Hermans, Philippe / Vanderfaeillie, Anna / Van Den Neste, Eric W / Benghiat, Fleur S / Kesse-Adu, Rachel / Delannoy, André / Efira, André / Azerad, Marie-Agnès / de Borgie, Corianne A /
    Biemond, Bart J

    British journal of haematology

    2017  Band 182, Heft 3, Seite(n) 444–448

    Mesh-Begriff(e) Acetylcysteine/adverse effects ; Acetylcysteine/pharmacology ; Acetylcysteine/therapeutic use ; Adolescent ; Adult ; Anemia, Sickle Cell/drug therapy ; Anemia, Sickle Cell/pathology ; Antioxidants ; Child ; Female ; Humans ; Male ; Medication Adherence ; Pain/prevention & control ; Treatment Outcome ; Young Adult
    Chemische Substanzen Antioxidants ; Acetylcysteine (WYQ7N0BPYC)
    Sprache Englisch
    Erscheinungsdatum 2017-06-23
    Erscheinungsland England
    Dokumenttyp Letter ; Multicenter Study ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
    ZDB-ID 80077-6
    ISSN 1365-2141 ; 0007-1048
    ISSN (online) 1365-2141
    ISSN 0007-1048
    DOI 10.1111/bjh.14809
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel: Expression of the fibroblast/macrophage marker 1B10 by spindle cells in Kaposi's sarcoma lesions and by Kaposi's sarcoma-derived tumor cells.

    Simonart, Thierry / Degraef, Chantale / Heenen, Michel / Hermans, Philippe / Van Vooren, Jean-Paul / Noel, Jean-Christophe

    Journal of cutaneous pathology

    2002  Band 29, Heft 2, Seite(n) 72–78

    Abstract: Background: Kaposi's sarcoma (KS) is a tumor whose ontogenic origin remains a matter of contention. KS tissues are characterized by predominant expression of endothelial markers, while KS-derived cell cultures are usually characterized by expression of ... ...

    Abstract Background: Kaposi's sarcoma (KS) is a tumor whose ontogenic origin remains a matter of contention. KS tissues are characterized by predominant expression of endothelial markers, while KS-derived cell cultures are usually characterized by expression of mesenchymal non-endothelial cell markers.
    Aims: In order to clarify the ontogenic origin of KS cells, we investigated the expression of the fibroblast/macrophage marker 1B10 in KS tissues (AIDS-associated KS, n = 9; classic KS, n = 6; iatrogenic KS, n = 6) and in KS-derived cell cultures.
    Results: 1B10 was expressed by loosely distributed spindle-shaped cells in early 'patch-stage' KS and by a variable proportion of spindle cells in late 'plaque- and nodular-stage' KS. Using immunohistochemistry and immunoblot analysis, we found that, in vitro, reactivity for 1B10 was uniformly evidenced in fibroblasts and in KS-derived spindle cell cultures, irrespective of their histological or epidemiological setting. By contrast, vascular smooth muscle cells and endothelial cells were negative for 1B10.
    Conclusions: These results suggest that the KS spindle cells isolated in vitro may represent a particular subpopulation of the KS spindle cell compartment.
    Mesh-Begriff(e) Antigens, Surface/analysis ; Antigens, Surface/biosynthesis ; Biomarkers, Tumor/analysis ; Biopsy ; Fibroblasts/metabolism ; Immunohistochemistry ; Macrophages/metabolism ; Sarcoma, Kaposi/metabolism ; Sarcoma, Kaposi/pathology ; Skin Neoplasms/metabolism ; Skin Neoplasms/pathology ; Tumor Cells, Cultured
    Chemische Substanzen Antigens, Surface ; Biomarkers, Tumor
    Sprache Englisch
    Erscheinungsdatum 2002-02
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 187078-6
    ISSN 1600-0560 ; 0303-6987
    ISSN (online) 1600-0560
    ISSN 0303-6987
    DOI 10.1034/j.1600-0560.2002.290202.x
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel ; Online: Cultured Kaposi's sarcoma tumor cells exhibit a chemokine receptor repertoire that does not allow infection by HIV-1

    Hermans Philippe / de Lavareille Aurore / Delforge Marie-Luce / Debaisieux Laurent / Liesnard Corinne / Debussher Claire / Simonart Thierry / Van Vooren Jean-Paul / Stordeur Patrick

    BMC Dermatology, Vol 1, Iss 1, p

    2001  Band 2

    Abstract: Abstract Background HIV-1 is known to play a critical role in the pathogenesis of AIDS-associated Kaposi's sarcoma (KS). However, it remains controversial whether KS cells are target cells for HIV infection. The aim of this study was to investigate the ... ...

    Abstract Abstract Background HIV-1 is known to play a critical role in the pathogenesis of AIDS-associated Kaposi's sarcoma (KS). However, it remains controversial whether KS cells are target cells for HIV infection. The aim of this study was to investigate the expression of chemokine receptors in KS cell cultures and to determine whether these cells can be infected by HIV-1. Material and Methods KS-derived cells and KS-Y1 cells were investigated using RT-PCR for the expression of CD4, CCR3, CCR5, CCR8 and CXCR4 mRNA. HIV infectivity of these cells was determined by p24 antigen and HIV-1 RNA production, as well as by HIV-1 DNA integration. Results and Discussion With the exception of CCR8 which is expressed by KS-derived spindle cell cultures but not by KS-Y1 cells, unstimulated KS cells express no significant levels of CD4, CCR3, CCR5 or CXCR4 mRNA. HIV infectivity assays showed that KS cells were unpermissive to HTLVIIIB and JRFL strains. Although the expression of CXCR4 mRNA could be upregulated by interleukin-1β, stimulation of KS cells by this cytokine did not allow infection by HIV-1. Conclusions This shows that KS cells exhibit a chemokine receptor repertoire that does not allow infection by HIV-1. Other cell types making up KS lesions, such as inflammatory cells, are likely to represent the source of HIV-1 products cooperating to promote KS development and progression.
    Schlagwörter Dermatology ; RL1-803 ; Medicine ; R ; DOAJ:Dermatology ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
    Thema/Rubrik (Code) 570
    Sprache Englisch
    Erscheinungsdatum 2001-07-01T00:00:00Z
    Verlag BioMed Central
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  9. Artikel: Rising prevalence of HIV-1 non-B subtypes in Belgium: 1983-2001.

    Snoeck, Joke / Van Laethem, Kristel / Hermans, Philippe / Van Wijngaerden, Eric / Derdelinckx, Inge / Schrooten, Yoeri / van de Vijver, David A M C / De Wit, Stéphanie / Clumeck, Nathan / Vandamme, Anne-Mieke

    Journal of acquired immune deficiency syndromes (1999)

    2004  Band 35, Heft 3, Seite(n) 279–285

    Abstract: This study documented the HIV-1 subtype distribution in 2 Belgian hospitals and determined predictive demographics for non-B subtypes. Overall, subtype B was the most prevalent subtype in this population, followed by subtypes A and C. Several ... ...

    Abstract This study documented the HIV-1 subtype distribution in 2 Belgian hospitals and determined predictive demographics for non-B subtypes. Overall, subtype B was the most prevalent subtype in this population, followed by subtypes A and C. Several recombinants were detected, circulating recombinants as well as new ones. We found a rise in non-B subtypes from 0% in 1983 to 57% in 2001. The Cochran-Armitage trend test (P < 0.001) as well as the correlation analysis (R = 0.71, P = 0.0006) was highly significant. Recombinants were also increasing in this patient population from 0% in 1983 to 10% in 2001, with good support from the statistical analyses (trend test P < 0.001; correlation analysis R = 0.67, P = 0.0016). Heterosexual route of infection, black African race, African origin of the virus, and year of diagnosis were predictors for infection with non-B subtypes in multivariate analysis. This analysis indicates that the prevalence of non-B subtypes and recombinants in this patient population is high and increasing. Gathering demographic and sequence information from newly diagnosed patients could be useful to further follow the spread of non-B subtypes in Belgium and Europe, but subtyping based on sequence information still remains the most reliable method.
    Mesh-Begriff(e) Acquired Immunodeficiency Syndrome/classification ; Acquired Immunodeficiency Syndrome/epidemiology ; Adult ; Belgium/epidemiology ; Continental Population Groups ; Female ; Geography ; HIV Infections/classification ; HIV Infections/epidemiology ; HIV-1/classification ; HIV-1/isolation & purification ; Humans ; Male ; Sexual Behavior
    Sprache Englisch
    Erscheinungsdatum 2004-04-09
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 645053-2
    ISSN 1944-7884 ; 1077-9450 ; 1525-4135 ; 0897-5965 ; 0894-9255
    ISSN (online) 1944-7884 ; 1077-9450
    ISSN 1525-4135 ; 0897-5965 ; 0894-9255
    DOI 10.1097/00126334-200403010-00009
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  10. Artikel: A clinically prognostic scoring system for patients receiving highly active antiretroviral therapy: results from the EuroSIDA study.

    Lundgren, Jens D / Mocroft, Amanda / Gatell, Jose M / Ledergerber, Bruno / D'Arminio Monforte, Antonella / Hermans, Philippe / Goebel, Frank-Detlef / Blaxhult, Anders / Kirk, Ole / Phillips, Andrew N

    The Journal of infectious diseases

    2002  Band 185, Heft 2, Seite(n) 178–187

    Abstract: The risk of clinical progression for human immunodeficiency virus (HIV)-infected persons receiving treatment with highly active antiretroviral therapy (HAART) is poorly defined. From an inception cohort of 8457 HIV-infected persons, 2027 patients who ... ...

    Abstract The risk of clinical progression for human immunodeficiency virus (HIV)-infected persons receiving treatment with highly active antiretroviral therapy (HAART) is poorly defined. From an inception cohort of 8457 HIV-infected persons, 2027 patients who started HAART during prospective follow-up were examined. Results were validated in another 2 groups of patients (n=1946 and n=1442). In total, 200 patients (9.9%) experienced clinical progression during 5177 person-years (incidence, 3.9/100 years). The most recently measured CD4 cell count, virus load, and hemoglobin level all were independently related to the risk of clinical progression, as was a diagnosis of severe AIDS before the start of HAART. On the basis of these findings, a scoring system was derived (range, 0-17). A single unit increase in the score was associated with a 38% increased risk of clinical progression (relative hazard, 1.38; 95% confidence interval, 1.33-1.43; P<.0001). The scoring system was validated with remarkably good agreement in the 2 other cohorts. This system can be used in patient and resource management.
    Mesh-Begriff(e) Adult ; Antiretroviral Therapy, Highly Active ; CD4 Lymphocyte Count ; Cohort Studies ; Female ; HIV Infections/drug therapy ; HIV Infections/immunology ; Humans ; Male ; Prognosis ; Prospective Studies
    Sprache Englisch
    Erscheinungsdatum 2002-01-15
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 3019-3
    ISSN 1537-6613 ; 0022-1899
    ISSN (online) 1537-6613
    ISSN 0022-1899
    DOI 10.1086/338267
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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