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  1. Article ; Online: Myoepithelioma-like hyalinising epithelioid tumour of the foot: biopsy diagnosis, with molecular confirmation.

    Neyaz, Azfar / Omman, Reeba A / Wald, Abigail I / Herradura, Armando / Fritchie, Karen J / John, Ivy

    Histopathology

    2022  Volume 81, Issue 6, Page(s) 847–849

    MeSH term(s) Humans ; Myoepithelioma/diagnosis ; Myoepithelioma/pathology ; Biopsy ; Neoplasms
    Language English
    Publishing date 2022-09-19
    Publishing country England
    Document type Letter
    ZDB-ID 131914-0
    ISSN 1365-2559 ; 0309-0167
    ISSN (online) 1365-2559
    ISSN 0309-0167
    DOI 10.1111/his.14788
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1328: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Epithelioid inflammatory myofibroblastic sarcomas are not exclusive to ventral cavity sites.

    Zilla, Megan L / Khoshnoodi, Pooria / Bailey, Nathanael G / Herradura, Armando / Lee, Stella J / John, Ivy

    Histopathology

    2021  Volume 80, Issue 3, Page(s) 610–612

    MeSH term(s) Abdominal Neoplasms/genetics ; Abdominal Neoplasms/pathology ; Aged, 80 and over ; Anaplastic Lymphoma Kinase/genetics ; Epithelioid Cells/pathology ; Exons ; Gene Fusion ; Groin ; Humans ; Male ; Molecular Chaperones/genetics ; Nuclear Pore Complex Proteins/genetics ; Sarcoma/genetics ; Sarcoma/pathology ; Soft Tissue Neoplasms/genetics ; Soft Tissue Neoplasms/pathology
    Chemical Substances Molecular Chaperones ; Nuclear Pore Complex Proteins ; ran-binding protein 2 ; ALK protein, human (EC 2.7.10.1) ; Anaplastic Lymphoma Kinase (EC 2.7.10.1)
    Language English
    Publishing date 2021-12-13
    Publishing country England
    Document type Case Reports ; Letter
    ZDB-ID 131914-0
    ISSN 1365-2559 ; 0309-0167
    ISSN (online) 1365-2559
    ISSN 0309-0167
    DOI 10.1111/his.14582
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1328: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Osteoid osteomas of the hands and feet: a series of 71 cases.

    Alruwaii, Fatimah / Molligan, Jeremiah F / Ilaslan, Hakan / John, Ivy / Herradura, Armando S / Alkashash, Ahmad / Chen, Shaoxiong / Nystrom, Lukas / Kilpatrick, Scott E / Reith, John D / Wenger, Doris E / Powell, Garret M / Fritchie, Karen J

    Virchows Archiv : an international journal of pathology

    2023  Volume 483, Issue 1, Page(s) 41–46

    Abstract: Osteoid osteomas typically arise in the long bones of extremities. Patients often report pain relieved by NSAIDS, and radiographic findings are often sufficient for diagnosis. However, when involving the hands/feet, these lesions may go unrecognized or ... ...

    Abstract Osteoid osteomas typically arise in the long bones of extremities. Patients often report pain relieved by NSAIDS, and radiographic findings are often sufficient for diagnosis. However, when involving the hands/feet, these lesions may go unrecognized or misdiagnosed radiographically due to their small size and prominent reactive changes. The clinicopathologic features of this entity involving the hands and feet are not well-described. Our institutional and consultation archives were searched for all cases of pathologically confirmed osteoid osteomas arising in the hands and feet. Clinical data was obtained and recorded. Seventy-one cases (45 males and 26 females, 7 to 64 years; median 23 years) arose in the hands and feet, representing 12% of institutional and 23% of consultation cases. The clinical impression often included neoplastic and inflammatory etiologies. Radiology studies demonstrated a small lytic lesion in all cases (33/33), the majority of which had a tiny focus of central calcification (26/33). Nearly, all cases demonstrated cortical thickening and/or sclerosis and perilesional edema which almost always had an extent two times greater than the size of the nidus. Histologic examination showed circumscribed osteoblastic lesions with formation of variably mineralized woven bone with single layer of osteoblastic rimming. The most common growth pattern of bone was trabecular (n = 34, 48%) followed by combined trabecular and sheet-like (n = 26, 37%) with only 11 (15%) cases presenting with pure sheet-like growth pattern. The majority (n = 57, 80%) showed intra-trabecular vascular stroma. No case showed significant cytology atypia. Follow up was available for 48 cases (1-432 months), and 4 cases recurred. Osteoid osteomas involving the hands and feet follow a similar age and sex distribution as their non-acral counterparts. These lesions often present with a broad differential diagnosis and may initially be confused with chronic osteomyelitis or a reactive process. While the majority of cases have classic morphologic features on histologic exam, a small subset consists solely of sheet-like sclerotic bone. Awareness that this entity may present in the hands and feet will help pathologists, radiologists, and clinicians accurately diagnose these tumors.
    MeSH term(s) Male ; Female ; Humans ; Osteoma, Osteoid/diagnosis ; Osteoma, Osteoid/pathology ; Bone Neoplasms/pathology ; Neoplasm Recurrence, Local/diagnosis ; Bone and Bones ; Diagnosis, Differential
    Language English
    Publishing date 2023-06-09
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1184867-4
    ISSN 1432-2307 ; 0945-6317
    ISSN (online) 1432-2307
    ISSN 0945-6317
    DOI 10.1007/s00428-023-03576-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ud III Zs.10: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Expanding the molecular signatures of malignant ossifying fibromyxoid tumours with two novel gene fusions: PHF1::FOXR1 and PHF1::FOXR2.

    Srivastava, Pooja / Zilla, Megan L / Naous, Rana / Marker, Daniel / Khoshnoodi, Pooria / Burgess, Melissa / Herradura, Armando / Wu, Jinhua / Surrey, Lea F / John, Ivy

    Histopathology

    2023  Volume 82, Issue 6, Page(s) 946–952

    Abstract: Aims: Ossifying fibromyxoid tumor (OFMT) is a rare enigmatic tumor of uncertain differentiation that can be classified as typical, atypical, and malignant subtypes based on cellularity, nuclear grade, and mitotic activity. The majority of OFMTs, ... ...

    Abstract Aims: Ossifying fibromyxoid tumor (OFMT) is a rare enigmatic tumor of uncertain differentiation that can be classified as typical, atypical, and malignant subtypes based on cellularity, nuclear grade, and mitotic activity. The majority of OFMTs, regardless of the risk of malignancy, harbor genetic translocations. We report two malignant OFMTs, including one with evidence of dedifferentiation, with novel genefusions.
    Methods and results: Case 1 was a 63-year-old male with a dedifferentiated OFMT arising in the right wrist, while case 2 was a 41-year-old male with a malignant OFMT presenting as a posterior mediastinal mass. Case 2 showed multifocal expression with EMA and synaptophysin, while desmin and S100 were absent in both tumors. NGS sequencing studies detected PHF1::FOXR1 and PHF1::FOXR2 gene fusions in cases 1 and 2, respectively. Despite aggressive regimens, both progressed with wide spread metastases resulting in death within six years of diagnosis.
    Conclusions: We expand the genetic spectrum of OFMTs with two novel gene fusions, PHF1::FOXR1 and PHF1::FOXR2. These cases confirm the previously reported tendencies for OFMTs with rare variant fusions to demonstrate malignant behavior, unusual morphology, and non-specific immunophenotype.
    MeSH term(s) Male ; Humans ; Middle Aged ; Adult ; Fibroma, Ossifying/pathology ; Soft Tissue Neoplasms/pathology ; Fibroma/pathology ; Gene Fusion ; DNA-Binding Proteins/genetics ; Polycomb-Group Proteins/genetics ; Polycomb-Group Proteins/metabolism ; Forkhead Transcription Factors/genetics
    Chemical Substances PHF1 protein, human ; DNA-Binding Proteins ; Polycomb-Group Proteins ; FOXR2 protein, human ; Forkhead Transcription Factors
    Language English
    Publishing date 2023-02-06
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 131914-0
    ISSN 1365-2559 ; 0309-0167
    ISSN (online) 1365-2559
    ISSN 0309-0167
    DOI 10.1111/his.14868
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1328: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Novel APOD-GLI1 rearrangement in a sarcoma of unknown lineage.

    Lopez-Nunez, Oscar / Surrey, Lea F / Alaggio, Rita / Herradura, Armando / McGough, Richard L / John, Ivy

    Histopathology

    2020  Volume 78, Issue 2, Page(s) 338–340

    MeSH term(s) Adult ; Apolipoproteins D ; Female ; High-Throughput Nucleotide Sequencing ; Humans ; Oncogene Proteins, Fusion ; Sarcoma/classification ; Sarcoma/diagnosis ; Sarcoma/genetics ; Sarcoma/pathology ; Soft Tissue Neoplasms ; Thigh/pathology ; Zinc Finger Protein GLI1
    Chemical Substances Apolipoproteins D ; Oncogene Proteins, Fusion ; Zinc Finger Protein GLI1
    Language English
    Publishing date 2020-10-25
    Publishing country England
    Document type Case Reports ; Letter
    ZDB-ID 131914-0
    ISSN 1365-2559 ; 0309-0167
    ISSN (online) 1365-2559
    ISSN 0309-0167
    DOI 10.1111/his.14235
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1328: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

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