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  1. Book ; Online ; E-Book: Pflege-Pocket Zentrale Notaufnahme

    Welk, Ina / Kegel, Michael / Herrmann, Tobias

    häufige Krankheitsbilder - besondere Patientengruppen - Techniken von A bis Z

    2023  

    Abstract: Notfallpflege kompakt und strukturiert von A-Z Die Notaufnahme gehört für Pflegekräfte zu den vielschichtigsten und spannendsten Arbeitsbereichen. Hier sind schnelles und sicheres Handeln, Kompetenz und Umsicht gefragt. Das erfahrende Autorenteam zeigt, ... ...

    Author's details Ina Welk, Michael Kegel, Tobias Herrmann
    Abstract Notfallpflege kompakt und strukturiert von A-Z Die Notaufnahme gehört für Pflegekräfte zu den vielschichtigsten und spannendsten Arbeitsbereichen. Hier sind schnelles und sicheres Handeln, Kompetenz und Umsicht gefragt. Das erfahrende Autorenteam zeigt, was wichtig ist und wie man den Alltag meistern kann. Fachwissen konkret · Leitsymptomorientierung mit praxisnahen Handlungsempfehlungen · Sicheres Handeln im traumatologischen und nicht-traumatologischen Schockraum · die wichtigsten Pflegetechniken, diagnostische und apparative Maßnahmen von A-Z · Der besondere Patient: u. a. Schwangere, Patienten nach Gewaltdelikten, Menschen mit Demenz, Kinder Hilfreich für den ZNA-Alltag Tipps zum Anleiten und Beraten Gesprächsführung mit Patienten und Angehörigen in Akutsituationen Fakten im Überblick: Algorithmen, Skalen u.v.m. Die 2. Auflage wurde komplett überarbeitet und aktualisiert! Das Autorenteam: Ina Welk, Fachpflegekraft für Intensiv- und Anästhesiepflege, Pflegemanagerin, Erfahrung im Bereich Notaufnahme und Notfallpflege Michael Kegel (M.A.), Leitung der Fachweiterbildung für Notfallpflege an der Bildungsakademie der Gesundheit-Nord am Klinikum Links der Weser in Bremen, Sprecher der DGINA AG Notfallpflege Tobias Herrmann, Fachkrankenpfleger für Notfallpflege in der Zentralen Notfallambulanz am Städt. Klinikum Solingen gGmbH, Sprecher der DGINA AG Notfallpflege .
    Keywords Nursing ; Emergency medicine ; Medical sciences ; Public health ; Primary care (Medicine)
    Language German
    Size 1 Online-Ressource (XVI, 304 Seiten)
    Edition 2., vollständig überarbeitete Auflage
    Publisher Springer
    Publishing place Berlin
    Publishing country Germany
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT030717810
    ISBN 978-3-662-66586-2 ; 9783662665855 ; 3-662-66586-7 ; 3662665859
    DOI 10.1007/978-3-662-66586-2
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Conference proceedings: Planung und Umsetzung einer komplexen Intervention im Rahmen des Innovationsfonds: Das DEMAND-Projekt

    Herrmann, Tobias

    2019  , Page(s) 19dkvf070

    Event/congress 18. Deutscher Kongress für Versorgungsforschung (DKVF); Berlin; Deutsches Netzwerk Versorgungsforschung; 2019
    Keywords Medizin, Gesundheit
    Publishing date 2019-10-02
    Publisher German Medical Science GMS Publishing House; Düsseldorf
    Document type Conference proceedings
    DOI 10.3205/19dkvf070
    Database German Medical Science

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  3. Article ; Online: The rotavirus VP5*/VP8* conformational transition permeabilizes membranes to Ca2.

    de Sautu, Marilina / Herrmann, Tobias / Scanavachi, Gustavo / Jenni, Simon / Harrison, Stephen C

    PLoS pathogens

    2024  Volume 20, Issue 4, Page(s) e1011750

    Abstract: Rotaviruses infect cells by delivering into the cytosol a transcriptionally active inner capsid particle (a "double-layer particle": DLP). Delivery is the function of a third, outer layer, which drives uptake from the cell surface into small vesicles ... ...

    Abstract Rotaviruses infect cells by delivering into the cytosol a transcriptionally active inner capsid particle (a "double-layer particle": DLP). Delivery is the function of a third, outer layer, which drives uptake from the cell surface into small vesicles from which the DLPs escape. In published work, we followed stages of rhesus rotavirus (RRV) entry by live-cell imaging and correlated them with structures from cryogenic electron microscopy and tomography (cryo-EM and cryo-ET). The virus appears to wrap itself in membrane, leading to complete engulfment and loss of Ca2+ from the vesicle produced by the wrapping. One of the outer-layer proteins, VP7, is a Ca2+-stabilized trimer; loss of Ca2+ releases both VP7 and the other outer-layer protein, VP4, from the particle. VP4, activated by cleavage into VP8* and VP5*, is a trimer that undergoes a large-scale conformational rearrangement, reminiscent of the transition that viral fusion proteins undergo to penetrate a membrane. The rearrangement of VP5* thrusts a 250-residue, C-terminal segment of each of the three subunits outward, while allowing the protein to remain attached to the virus particle and to the cell being infected. We proposed that this segment inserts into the membrane of the target cell, enabling Ca2+ to cross. In the work reported here, we show the validity of key aspects of this proposed sequence. By cryo-EM studies of liposome-attached virions ("triple-layer particles": TLPs) and single-particle fluorescence imaging of liposome-attached TLPs, we confirm insertion of the VP4 C-terminal segment into the membrane and ensuing generation of a Ca2+ "leak". The results allow us to formulate a molecular description of early events in entry. We also discuss our observations in the context of other work on double-strand RNA virus entry.
    MeSH term(s) Rotavirus/genetics ; Capsid Proteins/metabolism ; Capsid/metabolism ; Calcium/metabolism ; Liposomes/analysis ; Liposomes/metabolism
    Chemical Substances Capsid Proteins ; Calcium (SY7Q814VUP) ; Liposomes
    Language English
    Publishing date 2024-04-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2205412-1
    ISSN 1553-7374 ; 1553-7374
    ISSN (online) 1553-7374
    ISSN 1553-7374
    DOI 10.1371/journal.ppat.1011750
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: The rotavirus VP5*/VP8* conformational transition permeabilizes membranes to Ca

    De Sautu, Marilina / Herrmann, Tobias / Jenni, Simon / Harrison, Stephen C

    bioRxiv : the preprint server for biology

    2023  

    Abstract: Rotaviruses infect cells by delivering into the cytosol a transcriptionally active inner capsid particle (a "double-layer particle": DLP). Delivery is the function of a third, outer layer, which drives uptake from the cell surface into small vesicles ... ...

    Abstract Rotaviruses infect cells by delivering into the cytosol a transcriptionally active inner capsid particle (a "double-layer particle": DLP). Delivery is the function of a third, outer layer, which drives uptake from the cell surface into small vesicles from which the DLPs escape. In published work, we followed stages of rhesus rotavirus (RRV) entry by live-cell imaging and correlated them with structures from cryogenic electron microscopy and tomography (cryo-EM and cryo-ET). The virus appears to wrap itself in membrane, leading to complete engulfment and loss of Ca
    Language English
    Publishing date 2023-10-16
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2023.10.15.562449
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Conference proceedings: Evaluation einer standardisierten Ersteinschätzung in der ambulanten Notfallversorgung anhand von GKV-Routinedaten – Ergebnisse aus dem Projekt DEMAND

    Pollmann, Thorsten / Grobe, Thomas / Herrmann, Tobias

    2023  , Page(s) 23dkvf461

    Event/congress 22. Deutscher Kongress für Versorgungsforschung (DKVF); Berlin; Deutsches Netzwerk Versorgungsforschung; 2023
    Keywords Medizin, Gesundheit
    Publishing date 2023-10-02
    Publisher German Medical Science GMS Publishing House; Düsseldorf
    Document type Conference proceedings
    DOI 10.3205/23dkvf461
    Database German Medical Science

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  6. Book ; Thesis: Entwicklung einer neuen N-Oxid-vermittelten Hydroxylierung von Arylborspezies und deren Anwendung zur Phenolsynthese und Wirkstoffmodifikation ausgehend von Arylhalogeniden

    Herrmann, Tobias

    2015  

    Author's details vorgelegt von Tobias Herrmann
    Language German
    Size III, 245 S., graph. Darst.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Univ., FB Chemie, Diss. 2015--Hamburg, 2015
    Note Zsfassung in dt. und engl. Sprache
    Database Former special subject collection: coastal and deep sea fishing

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  7. Article ; Online: Patient satisfaction with computer-assisted structured initial assessment facilitating patient streaming to emergency departments and primary care practices: results from a cross-sectional observational study accompanying the DEMAND intervention in Germany.

    Schäfer, Ingmar / Menzel, Agata / Herrmann, Tobias / Oltrogge, Jan Hendrik / Lühmann, Dagmar / Scherer, Martin

    BMC primary care

    2022  Volume 23, Issue 1, Page(s) 213

    Abstract: Background: Patient numbers in emergency departments are on the rise. The DEMAND intervention aims to improve the efficacy of emergency services by computer-assisted structured initial assessment assigning patients to emergency departments or primary ... ...

    Abstract Background: Patient numbers in emergency departments are on the rise. The DEMAND intervention aims to improve the efficacy of emergency services by computer-assisted structured initial assessment assigning patients to emergency departments or primary care practices. The aims of our study were to evaluate patient satisfaction with this intervention and to analyse if reduced patient satisfaction is predicted by sociodemographic data, health status or health literacy.
    Methods: We conducted a cross-sectional patient survey in emergency departments and co-located primary care practices. Each intervention site was planned to participate for two observation periods, each with a duration of one full week. Study participants were recruited by the local staff. The patients filled out a written questionnaire during their waiting time. Patient satisfaction was assessed by agreement to four statements on a four point Likert scale. Predictors of patient satisfaction were identified by multilevel, multivariable logistic regression models adjusted for random effects at the intervention site level.
    Results: The sample included 677 patients from 10 intervention sites. The patients had a mean age of 38.9 years and 59.0% were women. Between 67.5% and 55.0% were fully satisfied with aspects of the intervention. The most criticised aspect was that the staff showed too little interest in the patients' personal situation. Full satisfaction ("clearly yes" to all items) was reported by 44.2%. Reduced patient satisfaction (at least one item rated as "rather yes", "rather no", "clearly no") was predicted by lower age (odds ratio 0.79 for ten years difference, 95% confidence interval 0.67/0.95, p = 0.009), presenting with infections (3.08,1.18/8.05,p = 0.022) or injuries (3.46,1.01/11.82,p = 0.048), a higher natural logarithm of the symptom duration (1.23,1.07/1.30,p = 0.003) and a lower health literacy (0.71 for four points difference, 0.53/0.94,p = 0.019).
    Conclusions: The patients were for the most part satisfied with the intervention. Assessment procedures should be evaluated a) regarding if all relevant patient-related aspects are included; and whether patient information can be improved b) for patients with strong opinions about cause, consequences and treatment options for their health problem; and c) for patients who have problems in the handling of information relevant to health and healthcare.
    Trial registration: German Clinical Trials Register ( https://www.drks.de/drks_web/setLocale_EN.do ) no. DRKS00017014.
    MeSH term(s) Adult ; Child ; Computers ; Cross-Sectional Studies ; Emergency Service, Hospital ; Female ; Germany ; Humans ; Male ; Patient Satisfaction ; Primary Health Care
    Language English
    Publishing date 2022-08-23
    Publishing country England
    Document type Journal Article ; Observational Study ; Research Support, Non-U.S. Gov't
    ISSN 2731-4553
    ISSN (online) 2731-4553
    DOI 10.1186/s12875-022-01825-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Book ; Online: CargoCBM - Zustandsorientierte Instandhaltungsdisposition/Condition Based Maintenance im Schienengüterverkehr am Beispiel eines vorhandenen Güterwagenfahrwerkes im CARGO-Bereich

    Hecht, Markus / Herrmann, Tobias

    Schlussbericht CargoCBM ; Schlussbericht des FG Schienenfahrzeuge der TU Berlin ; Projektlaufzeit: 01.01.2010 - 30.09.2013

    2014  

    Author's details Autoren: Markus Hecht (TU Berlin); Tobias Herrmann (TU Berlin)
    Language German ; English
    Size Online-Ressource (PDF-Datei: 38 S., 954 KB), Ill., graph. Darst.
    Publisher Techn. Informationsbibl. und Univ.-Bibl ; Techn. Univ. Berlin, Fak. V - Verkehrs- und Maschinensysteme, Inst. für Land- und Seeverkehr, Fachgebiet Schienenfahrzeuge
    Publishing place Hannover ; Berlin
    Document type Book ; Online
    Note Zsfassungen in dt. u. engl. Sprache ; Förderkennzeichen BMWi 19 G 9012 C. - Verbund-Nr. 01073839 ; Unterschiede zwischen dem gedruckten Dokument und der elektronischen Ressource können nicht ausgeschlossen werden
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  9. Book ; Thesis: Propriozeption des Kniegelenks

    Herrmann, Tobias

    ein Literaturüberblick

    2014  

    Author's details von Tobias Herrmann
    Size V, 45 Blatt: graphische Darstellungen
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Köln, Deutsche Sporthochschule, Bachelorarbeit, 2014
    HBZ-ID ZT000003814
    Database Central Library of Sport Science of the German Sport University Cologne

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  10. Article ; Online: Compliance and patient satisfaction with treatment settings recommended by the medical on-call service 116117 in Germany using computer-assisted structured initial assessment: a cross-sectional observational study accompanying the demand intervention.

    Schäfer, Ingmar / Menzel, Agata / Herrmann, Tobias / Willms, Gerald / Oltrogge, Jan Hendrik / Lühmann, Dagmar / Scherer, Martin

    BMJ open

    2023  Volume 13, Issue 5, Page(s) e070475

    Abstract: Objectives: In order to reduce the use of emergency departments, computer-assisted initial assessment was implemented at the medical on-call service 116117. Our study assessed compliance and patient satisfaction.: Design: Cross-sectional ... ...

    Abstract Objectives: In order to reduce the use of emergency departments, computer-assisted initial assessment was implemented at the medical on-call service 116117. Our study assessed compliance and patient satisfaction.
    Design: Cross-sectional observational postal survey.
    Setting: Medical on-call service 116117 by eight Associations of Statutory Health Insurance Physicians in Germany.
    Participants: The intervention was observed between January 2020 and March 2021. Minors and patients with invalid contact data were excluded. A random sample of eligible patients received standardised questionnaires by mail.
    Outcome measures: We analysed associations of sociodemographic data, health status, previous service use, health literacy, and recommended settings with compliance and patient satisfaction by multivariable, multilevel logistic regression.
    Interventions: Based on symptoms and context factors, the computer software suggested service levels. Staff and patient discussed if higher levels were indicated, services were available and self-transport was possible. They then agreed on recommendations for treatment settings.
    Results: Of 9473 contacted eligible patients, 1756 patients (18.5%) participated. Median age was 66 years (IQR=50-79), and 986 (59.0%) were women. At least one recommended setting was used by 1397 patients (85.4%). General practitioner (GP) practices were used by 143 patients (68.4%). Generally, better compliance was associated with lower depression levels (OR 1.59, 95% CI 1.17 to 2.17, p=0.003), fewer previous hospital stays (OR 2.02, 95% CI 1.27 to 3.23, p=0.003) and recommendations for any setting other than GP practices (OR 0.13, 95% CI 0.06 to 0.29, p<0001, to OR 0.37, 95% CI 0.19 to 0.72, p=0.003). A total of 606 patients (50.7%) were completely satisfied. Patient satisfaction was associated with higher age (OR 1.30, 95% CI 1.13 to 1.49, p<0.001), better self-rated health (OR 1.30, 95% CI 1.10 to 1.53, p=0.002), not having musculoskeletal disorders (OR 0.68, 95% CI 0.49 to 0.94, p=0.021), better health literacy (OR 0.69, 95% CI 0.54 to 0.89, p=0.005, and OR 0.49, 95% CI 0.36 to 0.67, p<0.001) and receiving no recommendation for GP practices (OR 0.61, 95% CI 0.43 to 0.87, p=0.006).
    Conclusions: Most patients were compliant and satisfied. Lowest compliance and satisfaction were found in GP practices, but nonetheless, two of three patients with respective recommendations were willing to use this setting.
    Trial registration number: German Clinical Trials Register DRKS00017014.
    MeSH term(s) Humans ; Female ; Aged ; Male ; Patient Satisfaction ; Cross-Sectional Studies ; Germany ; General Practitioners ; Computers
    Language English
    Publishing date 2023-05-09
    Publishing country England
    Document type Observational Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2599832-8
    ISSN 2044-6055 ; 2044-6055
    ISSN (online) 2044-6055
    ISSN 2044-6055
    DOI 10.1136/bmjopen-2022-070475
    Database MEDical Literature Analysis and Retrieval System OnLINE

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