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  1. Article ; Online: A safe method to evacuate pneumoperitoneum during laparoscopic surgery in suspected COVID-19 patients.

    Hanbali, N / Herrod, Pjj / Patterson, J

    Annals of the Royal College of Surgeons of England

    2020  Volume 102, Issue 5, Page(s) 392–393

    MeSH term(s) Betacoronavirus/isolation & purification ; COVID-19 ; Coronavirus Infections/complications ; Coronavirus Infections/transmission ; Disease Transmission, Infectious/prevention & control ; Humans ; Infection Control/methods ; Laparoscopy/adverse effects ; Laparoscopy/methods ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/transmission ; Pneumoperitoneum, Artificial/adverse effects ; Pneumoperitoneum, Artificial/methods ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-04-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 80044-2
    ISSN 1478-7083 ; 0035-8843
    ISSN (online) 1478-7083
    ISSN 0035-8843
    DOI 10.1308/rcsann.2020.0079
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Regarding "Cutaneous vascularization of the femoral triangle in respect to groin incisions".

    Herrod, Philip / McMahon, Greg

    Journal of vascular surgery

    2017  Volume 65, Issue 6, Page(s) 1872–1873

    Language English
    Publishing date 2017-06
    Publishing country United States
    Document type Letter
    ZDB-ID 605700-7
    ISSN 1097-6809 ; 0741-5214
    ISSN (online) 1097-6809
    ISSN 0741-5214
    DOI 10.1016/j.jvs.2016.12.130
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  3. Article ; Online: The importance of fluid and electrolyte management--a medical student's perspective.

    Herrod, Philip

    Clinical nutrition (Edinburgh, Scotland)

    2009  Volume 28, Issue 2, Page(s) 218

    MeSH term(s) Education, Medical, Undergraduate ; Health Knowledge, Attitudes, Practice ; Humans ; Students, Medical ; Water-Electrolyte Balance
    Language English
    Publishing date 2009-04
    Publishing country England
    Document type Comment ; Letter
    ZDB-ID 604812-2
    ISSN 1532-1983 ; 0261-5614
    ISSN (online) 1532-1983
    ISSN 0261-5614
    DOI 10.1016/j.clnu.2008.10.004
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  4. Article ; Online: Random duodenal biopsy to exclude coeliac disease as a cause of anaemia is not cost-efective and should be replaced with universally performed pre-endoscopy serology in patients on a suspected cancer pathway.

    Herrod, P J J / Lund, J N

    Techniques in coloproctology

    2018  Volume 22, Issue 2, Page(s) 121–124

    Abstract: Background: Random duodenal biopsy to exclude coeliac disease during upper gastrointestinal endoscopy for the investigation of iron deficiency anaemia remains a common procedure, but is expensive and time-consuming. Serological investigation for coeliac ...

    Abstract Background: Random duodenal biopsy to exclude coeliac disease during upper gastrointestinal endoscopy for the investigation of iron deficiency anaemia remains a common procedure, but is expensive and time-consuming. Serological investigation for coeliac disease is also recommended, having excellent accuracy with the added benefit of lower cost. This study sought to examine the utility of duodenal biopsy and coeliac serology in the diagnosis of coeliac disease.
    Methods: A prospectively maintained database was interrogated to identify all patients having upper gastrointestinal endoscopy for the investigation of anaemia between January 01, 2016, and December 31, 2016.
    Results: Of the 1131 patients having an endoscopy, coeliac serology was measured in only 412 (36%) and was positive in 9 cases (2%), leading to 6 histological diagnoses of coeliac disease and 3 false positives. Two-hundred and seventy-four patients with negative serology had biopsies taken which were all negative. Only 2/451 (0.4%) patients who had biopsies performed in the absence of a serology test were histologically positive for coeliac disease. The cost per diagnosis of a case of coeliac disease in those with either negative or absent coeliac serology was £18,839 (US$25,244, €21,196).
    Conclusions: Random duodenal biopsy is not a cost-effective method of diagnosing coeliac disease and should be replaced with pre-endoscopy coeliac serology.
    MeSH term(s) Anemia/diagnosis ; Anemia/etiology ; Biopsy/economics ; Biopsy/methods ; Celiac Disease/complications ; Celiac Disease/diagnosis ; Celiac Disease/pathology ; Cost-Benefit Analysis ; Databases, Factual ; Duodenum/pathology ; Duodenum/surgery ; Endoscopy, Gastrointestinal/economics ; Endoscopy, Gastrointestinal/methods ; False Positive Reactions ; Humans ; Prospective Studies ; Serologic Tests/economics ; Serologic Tests/methods
    Language English
    Publishing date 2018-02-23
    Publishing country Italy
    Document type Evaluation Studies ; Journal Article
    ZDB-ID 2083309-X
    ISSN 1128-045X ; 1123-6337
    ISSN (online) 1128-045X
    ISSN 1123-6337
    DOI 10.1007/s10151-018-1756-7
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  6. Article ; Online: CT-derived measures of muscle quantity and quality predict poorer outcomes from elective colorectal surgery: a UK multicentre retrospective cohort study.

    Blackwell, J E M / Herrod, P J J / Doleman, B / Boyd-Carson, H / Dolan, D / Wheldon, L / Brown, S R / Banerjea, A / Moug, S / Lund, J N

    Techniques in coloproctology

    2023  Volume 27, Issue 11, Page(s) 1091–1098

    Abstract: Purpose: To assess whether preoperative radiologically defined lean muscle measures are associated with adverse clinical outcomes in patients undergoing elective surgery for colorectal cancer.: Methods: This retrospective UK-based multicentre data ... ...

    Abstract Purpose: To assess whether preoperative radiologically defined lean muscle measures are associated with adverse clinical outcomes in patients undergoing elective surgery for colorectal cancer.
    Methods: This retrospective UK-based multicentre data collection study identified patients having had colorectal cancer resection with curative intent between January 2013 to December 2016. Preoperative computed-tomography (CT) scans were used to measure psoas muscle characteristics. Clinical records provided postoperative morbidity and mortality data.
    Results: This study included 1122 patients. The cohort was separated into a combined group (patients with both sarcopenia and myosteatosis) and others group (either sarcopenia or myosteatosis, or neither). For the combined group, anastomotic leak was predicted on univariate (OR 4.1, 95% CI 1.43-11.79; p = 0.009) and multivariate analysis (OR 4.37, 95% CI 1.41-13.53; p = 0.01). Also for the combined group, mortality (up to 5 years postoperatively) was predicted on univariate (HR 2.41, 95% CI 1.64-3.52; p < 0.001) and multivariate analysis (HR 1.93, 95% CI 1.28-2.89; p = 0.002). A strong correlation exists between freehand-drawn region of interest-derived psoas density measurement and using the ellipse tool (R
    Conclusion: Measures of lean muscle quality and quantity, which predict important clinical outcomes, can be quickly and easily taken from routine preoperative imaging in patients being considered for colorectal cancer surgery. As poor muscle mass and quality are again shown to predict poorer clinical outcomes, these should be proactively targeted within prehabilitation, perioperative and rehabilitation phases to minimise negative impact of these pathological states.
    MeSH term(s) Humans ; Sarcopenia/diagnostic imaging ; Sarcopenia/etiology ; Retrospective Studies ; Colorectal Surgery ; Postoperative Complications/etiology ; Risk Factors ; Colorectal Neoplasms/diagnostic imaging ; Colorectal Neoplasms/surgery ; Psoas Muscles/diagnostic imaging ; Psoas Muscles/pathology ; Tomography, X-Ray Computed/methods ; United Kingdom ; Muscle, Skeletal/diagnostic imaging ; Muscle, Skeletal/pathology
    Language English
    Publishing date 2023-05-03
    Publishing country Italy
    Document type Multicenter Study ; Journal Article
    ZDB-ID 2083309-X
    ISSN 1128-045X ; 1123-6337
    ISSN (online) 1128-045X
    ISSN 1123-6337
    DOI 10.1007/s10151-023-02769-3
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  7. Article ; Online: Appendix viriliformis: an intra-abdominal testis and an appendicoileal fistula.

    Herrod, P J J / Cirolli, R

    Annals of the Royal College of Surgeons of England

    2013  Volume 95, Issue 7, Page(s) e107–9

    Abstract: When a patient is taken to theatre for a laparotomy, surprises can still be found despite modern investigative techniques. We present the case of two rare abdominal pathologies (an appendicoileal fistula and an intra-abdominal testis adherent to the ... ...

    Abstract When a patient is taken to theatre for a laparotomy, surprises can still be found despite modern investigative techniques. We present the case of two rare abdominal pathologies (an appendicoileal fistula and an intra-abdominal testis adherent to the vermiform appendix) being found simultaneously and review the literature on these topics.
    MeSH term(s) Abdominal Pain/etiology ; Aged ; Appendicitis/complications ; Appendix/abnormalities ; Cecal Diseases/etiology ; Humans ; Ileal Diseases/etiology ; Incidental Findings ; Intestinal Fistula/etiology ; Male ; Testis/abnormalities ; Tomography, X-Ray Computed
    Language English
    Publishing date 2013-10-10
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 80044-2
    ISSN 1478-7083 ; 0035-8843
    ISSN (online) 1478-7083
    ISSN 0035-8843
    DOI 10.1308/003588413X13511609957614
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  8. Article ; Online: NICE guidance on sepsis is of limited value in postoperative colorectal patients: the scores that cry 'wolf!'

    Herrod, Pjj / Cox, M / Keevil, H / Smith, Kje / Lund, J N

    Annals of the Royal College of Surgeons of England

    2018  Volume 100, Issue 4, Page(s) 275–278

    Abstract: Background and aims Late recognition of sepsis and consequent death remains a problem. To address this, the National Institute for Health and Care Excellence has published updated guidance recommending the use of the Quick Sequential Organ Failure ... ...

    Abstract Background and aims Late recognition of sepsis and consequent death remains a problem. To address this, the National Institute for Health and Care Excellence has published updated guidance recommending the use of the Quick Sequential Organ Failure Assessment (Q-SOFA) score when assessing patients at risk of sepsis following the publication of the Third International Consensus Definitions for Sepsis and Septic Shock. The trauma from major surgery produces a systemic inflammatory response syndrome (SIRS) postoperatively as part of its natural history, which may falsely trigger scoring systems. We aimed to assess the accuracy of Q-SOFA and SIRS criteria as recommended scores for early detection of sepsis and septic complications in the first 48hrs after colorectal cancer surgery. Methods We reviewed all elective major colorectal operations in a single centre during a 12-month period from prospectively maintained electronic records. Results One hundred and thirty nine patients were included in this study. In all, 29 patients developed postoperative infective complications in hospital. Nineteen patients triggered on SIRS without developing infective complications, while 42 patients triggered on Q-SOFA with no infective complications. The area under the ROC curve was 0.52 for Q-SOFA and 0.67 for SIRS. Discussion Q-SOFA appears to perform little better than a coin toss at identifying postoperative sepsis after colorectal cancer resection and is inferior to the SIRS criteria. More work is required to assess whether a combination of scoring criteria, biochemical markers and automated tools could increase accurate detection of postoperative infection and trigger early intervention.
    MeSH term(s) Aged ; Biomarkers/blood ; Colectomy/adverse effects ; Colorectal Neoplasms/surgery ; Female ; Hospital Mortality ; Humans ; Laparoscopy/adverse effects ; Male ; Organ Dysfunction Scores ; Postoperative Care/standards ; Postoperative Complications/blood ; Postoperative Complications/diagnosis ; Postoperative Complications/etiology ; Practice Guidelines as Topic ; ROC Curve ; Retrospective Studies ; Sepsis/blood ; Sepsis/diagnosis ; Sepsis/etiology ; Sepsis/mortality ; Systemic Inflammatory Response Syndrome/blood ; Systemic Inflammatory Response Syndrome/diagnosis ; Systemic Inflammatory Response Syndrome/etiology ; Systemic Inflammatory Response Syndrome/mortality
    Chemical Substances Biomarkers
    Language English
    Publishing date 2018-01-24
    Publishing country England
    Document type Comparative Study ; Journal Article
    ZDB-ID 80044-2
    ISSN 1478-7083 ; 0035-8843
    ISSN (online) 1478-7083
    ISSN 0035-8843
    DOI 10.1308/rcsann.2017.0227
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  9. Article ; Online: Fibrin glue is a quick and effective treatment for primary and recurrent pilonidal sinus disease.

    Sian, T S / Herrod, P J J / Blackwell, J E M / Hardy, E J O / Lund, J N

    Techniques in coloproctology

    2018  Volume 22, Issue 10, Page(s) 779–784

    Abstract: Background: Pilonidal sinus disease (PSD) is a common, chronic inflammatory condition involving hair follicles within the natal cleft. It mainly affects young males and creates a significant health, social and economic burden. Traditional surgery is ... ...

    Abstract Background: Pilonidal sinus disease (PSD) is a common, chronic inflammatory condition involving hair follicles within the natal cleft. It mainly affects young males and creates a significant health, social and economic burden. Traditional surgery is often radical resulting in pain, wound complications, long recovery times and poor cosmesis. The aim of our study was to evaluate fibrin glue as a primary treatment for PSD.
    Methods: Fibrin glue procedures for a single surgeon at our institution were identified from operative coding databases and the logbook from January 2011 to January 2016. Patients had curettage of the sinus with fibrin glue obliteration. Recurrence data was collected retrospectively.
    Results: One hundred and forty-six patients were identified; (115 (79%) males, mean age 30 (range 16-78 years). One hundred and forty-four (99%) were discharged the same day. Four (2.7%) were treated conservatively for wound discharge. Median operating time was 9 (range 4-28) min. There were 40 (27%) recurrences after one glue application. Median time to recurrence was 4 (range 0.25-36) months. Twenty-four (60%) of the recurrences had repeat glue treatment with 4 (16.6%) recurrences. After 2 rounds of treatment with glue alone, 126 out of 130 (96.9%) patients had healed.
    Conclusions: Fibrin glue application following curettage of the sinus is a quick and effective procedure for first and second line treatment of PSD.
    MeSH term(s) Adolescent ; Adult ; Aged ; Curettage/methods ; Female ; Fibrin Tissue Adhesive/therapeutic use ; Humans ; Male ; Middle Aged ; Operative Time ; Pilonidal Sinus/surgery ; Recurrence ; Retrospective Studies ; Tissue Adhesives/therapeutic use ; Treatment Outcome ; Young Adult
    Chemical Substances Fibrin Tissue Adhesive ; Tissue Adhesives
    Language English
    Publishing date 2018-11-09
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2083309-X
    ISSN 1128-045X ; 1123-6337
    ISSN (online) 1128-045X
    ISSN 1123-6337
    DOI 10.1007/s10151-018-1864-4
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  10. Article ; Online: Can mobile technology improve response times of junior doctors to urgent out-of-hours calls? A prospective observational study.

    Herrod, P J J / Barclay, C / Blakey, J D

    QJM : monthly journal of the Association of Physicians

    2014  Volume 107, Issue 4, Page(s) 271–276

    Abstract: Background: The Hospital at Night system has been widely adopted to manage Out-of-Hours workload. However, it has the potential to introduce delays and corruption of information. The introduction of newer technologies to replace landlines, pagers and ... ...

    Abstract Background: The Hospital at Night system has been widely adopted to manage Out-of-Hours workload. However, it has the potential to introduce delays and corruption of information. The introduction of newer technologies to replace landlines, pagers and paper may ameliorate these issues.
    Aim: To establish if the introduction of a Hospital at Night system supported by a wireless taskflow system affected the escalation of high Early Warning Scores (EWSs) to medical attention, and the time taken to medical review.
    Design: Prospective 'pre and post' observational study in a teaching hospital in the UK.
    Methods: Review of observation charts and medical records, and data extraction from the electronic taskflow system.
    Results: The implementation of a technology-supported Hospital at Night system was associated with a significant decrease in time to documentation of initial review in those who were reviewed. However, there was no change in the proportion of those with a high EWS that were reviewed, and throughout the study a majority of patients with high EWSs were not reviewed in accordance with guidelines.
    Conclusion: Introduction of a Hospital at Night system supported by mobile technology appeared to improve the transfer of information, but did not affect the nursing decision whether to escalate abnormal findings.
    MeSH term(s) After-Hours Care/organization & administration ; After-Hours Care/standards ; Computers, Handheld ; Emergencies ; England ; Hospital Communication Systems/organization & administration ; Hospitals, Teaching/organization & administration ; Hospitals, Teaching/standards ; Humans ; Kaplan-Meier Estimate ; Medical Staff, Hospital/organization & administration ; Medical Staff, Hospital/standards ; Outcome Assessment (Health Care)/methods ; Personnel Staffing and Scheduling/organization & administration ; Prospective Studies ; Time Factors ; Wireless Technology/organization & administration
    Language English
    Publishing date 2014-04
    Publishing country England
    Document type Journal Article ; Observational Study
    ZDB-ID 1199985-8
    ISSN 1460-2393 ; 0033-5622 ; 1460-2725
    ISSN (online) 1460-2393
    ISSN 0033-5622 ; 1460-2725
    DOI 10.1093/qjmed/hct242
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