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Article ; Online: An Assay to Study Intra-Chromosomal Deletions in Yeast.

Lucas, Bailey E / McPherson, Matthew T / Hawk, Tila M / Wilson, Lexia N / Kroh, Jacob M / Hickman, Kyle G / Fitzgerald, Sean R / Disbennett, W Miguel / Rollins, P Daniel / Hylton, Hannah M / Baseer, Mohammed A / Montgomery, Paige N / Wu, Jian-Qiu / Petreaca, Ruben C

Methods and protocols

2019  Volume 2, Issue 3

Abstract: An accurate DNA damage response pathway is critical for the repair of DNA double-strand breaks. Repair may occur by homologous recombination, of which many different sub-pathways have been identified. Some recombination pathways are conservative, meaning ...

Abstract An accurate DNA damage response pathway is critical for the repair of DNA double-strand breaks. Repair may occur by homologous recombination, of which many different sub-pathways have been identified. Some recombination pathways are conservative, meaning that the chromosome sequences are preserved, and others are non-conservative, leading to some alteration of the DNA sequence. We describe an in vivo genetic assay to study non-conservative intra-chromosomal deletions at regions of non-tandem direct repeats in
Language English
Publishing date 2019-08-26
Publishing country Switzerland
Document type Journal Article
ISSN 2409-9279
ISSN (online) 2409-9279
DOI 10.3390/mps2030074
Database MEDical Literature Analysis and Retrieval System OnLINE

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