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Article ; Online: IL-17 Receptor C Signaling Controls CD4

Schmidt, Tilman / Luebbe, Jonas / Kilian, Christoph / Riedel, Jan-Hendrik / Hiekmann, Sonja / Asada, Nariaki / Ginsberg, Pauline / Robben, Lennart / Song, Ning / Kaffke, Anna / Peters, Anett / Borchers, Alina / Flavell, Richard A / Gagliani, Nicola / Pelzcar, Penelope / Huber, Samuel / Huber, Tobias B / Turner, Jan-Eric / Paust, Hans-Joachim /
Krebs, Christian F / Panzer, Ulf

Journal of the American Society of Nephrology : JASN

2022  Volume 32, Issue 12, Page(s) 3081–3098

Abstract: Background: IL-17A-producing CD4: Methods: Crescentic GN (nephrotoxic nephritis) was induced in IL-17A, IFN: Results: We identified a specific expression of the IL-17 receptor A/C complex on CD4: Conclusions: Our findings indicate that IL-17 ... ...

Abstract Background: IL-17A-producing CD4
Methods: Crescentic GN (nephrotoxic nephritis) was induced in IL-17A, IFN
Results: We identified a specific expression of the IL-17 receptor A/C complex on CD4
Conclusions: Our findings indicate that IL-17 receptor C signaling has a previously unrecognized function in the regulation of CD4
MeSH term(s) Animals ; CD4-Positive T-Lymphocytes/immunology ; Glomerulonephritis/etiology ; Glomerulonephritis/immunology ; Interleukin-17/biosynthesis ; Male ; Mice ; Mice, Inbred C57BL ; Psoriasis/etiology ; Receptors, Interleukin/physiology ; Receptors, Interleukin-17/physiology ; Signal Transduction/physiology ; Th17 Cells/immunology
Chemical Substances IL17RC protein, human ; Il17ra protein, mouse ; Il17rc protein, mouse ; Interleukin-17 ; Receptors, Interleukin ; Receptors, Interleukin-17
Language English
Publishing date 2022-02-15
Publishing country United States
Document type Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID 1085942-1
ISSN 1533-3450 ; 1046-6673
ISSN (online) 1533-3450
ISSN 1046-6673
DOI 10.1681/ASN.2021030426
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ab Jg. 2022: Lesesaal (EG)
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Zs.A 3344: Show issues Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

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