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  1. Article ; Online: Cardiopulmonary exercise testing in younger patients with persistent dyspnea following acute, outpatient COVID-19 infection.

    Holley, Aaron B / Fabyan, Kimberly D / Haynes, Zachary A / Holtzclaw, Arthur W / Huprikar, Nikhil A / Shumar, John N / Sheth, Phorum S / Hightower, Stephanie L

    Physiological reports

    2024  Volume 12, Issue 3, Page(s) e15934

    Abstract: Studies using cardiopulmonary exercise testing (CPET) to evaluate persistent dyspnea following infection with COVID-19 have focused on older patients with co-morbid diseases who are post-hospitalization. Less attention has been given to younger patients ... ...

    Abstract Studies using cardiopulmonary exercise testing (CPET) to evaluate persistent dyspnea following infection with COVID-19 have focused on older patients with co-morbid diseases who are post-hospitalization. Less attention has been given to younger patients with post-COVID-19 dyspnea treated as outpatients for their acute infection. We sought to determine causes of persistent dyspnea in younger patients recovering from acute COVID-19 infection that did not require hospitalization. We collected data on all post-COVID-19 patients who underwent CPET in our clinic in the calendar year 2021. Data on cardiac function and respiratory response were abstracted, and diagnoses were assigned using established criteria. CPET data on 45 patients (238.3 ± 124 days post-test positivity) with a median age of 27.0 (22.0-40.0) were available for analysis. All but two (95.6%) were active-duty service members. The group showed substantial loss of aerobic capacity-average VO
    MeSH term(s) Humans ; Exercise Test/methods ; Outpatients ; COVID-19/complications ; Dyspnea/diagnosis ; Dyspnea/etiology ; Respiration ; Exercise Tolerance/physiology
    Language English
    Publishing date 2024-02-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2724325-4
    ISSN 2051-817X ; 2051-817X
    ISSN (online) 2051-817X
    ISSN 2051-817X
    DOI 10.14814/phy2.15934
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Post-COVID-19 Pulmonary Fibrosis: Novel Sequelae of the Current Pandemic.

    Ambardar, Shiva Rattan / Hightower, Stephanie L / Huprikar, Nikhil A / Chung, Kevin K / Singhal, Anju / Collen, Jacob F

    Journal of clinical medicine

    2021  Volume 10, Issue 11

    Abstract: Since the initial identification of the novel coronavirus SARS-CoV-2 in December 2019, the COVID-19 pandemic has become a leading cause of morbidity and mortality worldwide. As effective vaccines and treatments begin to emerge, it will become ... ...

    Abstract Since the initial identification of the novel coronavirus SARS-CoV-2 in December 2019, the COVID-19 pandemic has become a leading cause of morbidity and mortality worldwide. As effective vaccines and treatments begin to emerge, it will become increasingly important to identify and proactively manage the long-term respiratory complications of severe disease. The patterns of imaging abnormalities coupled with data from prior coronavirus outbreaks suggest that patients with severe COVID-19 pneumonia are likely at an increased risk of progression to interstitial lung disease (ILD) and chronic pulmonary vascular disease. In this paper, we briefly review the definition, classification, and underlying pathophysiology of interstitial lung disease (ILD). We then review the current literature on the proposed mechanisms of lung injury in severe COVID-19 infection, and outline potential viral- and immune-mediated processes implicated in the development of post-COVID-19 pulmonary fibrosis (PCPF). Finally, we address patient-specific and iatrogenic risk factors that could lead to PCPF and discuss strategies for reducing risk of pulmonary complications/sequelae.
    Language English
    Publishing date 2021-06-01
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm10112452
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Recurrent Inactive Hydatid Cyst of the Liver Causing Restrictive Pulmonary Physiology.

    Boyce, Dacia S K / Ellis, John S / Hightower, Stephanie L / Lew, Jeffery L / Price, Michael W / Lin-Hurtubise, Kevin M / Hostler, Jordanna M

    Hawai'i journal of health & social welfare

    2019  Volume 78, Issue 7, Page(s) 230–235

    Abstract: Hydatid and alveolar cysts are formed by the ... ...

    Abstract Hydatid and alveolar cysts are formed by the helminths
    MeSH term(s) Aged ; Animals ; Echinococcosis/complications ; Echinococcosis/diagnosis ; Echinococcus granulosus/pathogenicity ; Egypt ; Humans ; Liver/abnormalities ; Liver/physiopathology ; Lung Diseases, Obstructive/etiology ; Lung Diseases, Obstructive/physiopathology ; Male ; Radiography/methods ; Recurrence ; Tomography, X-Ray Computed/methods ; Ultrasonography/methods
    Language English
    Publishing date 2019-08-29
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2983566-5
    ISSN 2641-5224 ; 2641-5216
    ISSN (online) 2641-5224
    ISSN 2641-5216
    Database MEDical Literature Analysis and Retrieval System OnLINE

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