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  1. Article ; Online: Probabilistic risk assessment of residential exposure to metal(loid)s in a mining impacted community.

    Huerta, Diego / Schobel, Taylor / Alexander-Ozinskas, Annika / Hild, Joanne / Lauder, Jeff / Reynolds, Peggy / Von Behren, Julie / Meltzer, Dan / Ramírez-Andreotta, Mónica D

    The Science of the total environment

    2023  Volume 872, Page(s) 162228

    Abstract: The "Gold Country" region of California is impacted by legacy and active gold mines. Concomitantly, Gold Country has an increased rate of female breast cancer relative to the state average. Using community-based participatory research methods, 40 ... ...

    Abstract The "Gold Country" region of California is impacted by legacy and active gold mines. Concomitantly, Gold Country has an increased rate of female breast cancer relative to the state average. Using community-based participatory research methods, 40 participants completed surveys and collected a total of 354 water, soil, home-grown foods, and dust samples from their homes, which we compared to state, federal, and international contamination standards for arsenic, cadmium, and lead. All soil samples exceeded U.S. EPA and California EPA soil standards for arsenic. When comparing other media to state, federal and international standards for arsenic, cadmium, and lead, 15 additional exceedances for indoor/outdoor dust, drinking water, and/or vegetable were documented. A probabilistic risk assessment was conducted to determine an adult female's exposure to arsenic, cadmium, and lead and estimated risk. Arsenic exposure, due largely to water (63.5 %) and homegrown food (33.3 %), presents carcinogenic risks in excess of the EPA recommended upper limit for contaminated sites (1 × 10
    MeSH term(s) Adult ; Humans ; Female ; Arsenic/analysis ; Cadmium ; Soil Pollutants/analysis ; Environmental Exposure/analysis ; Gold ; Dust/analysis ; Drinking Water/analysis ; Risk Assessment ; Breast Neoplasms ; Soil
    Chemical Substances Arsenic (N712M78A8G) ; Cadmium (00BH33GNGH) ; Soil Pollutants ; Gold (7440-57-5) ; Dust ; Drinking Water ; Soil
    Language English
    Publishing date 2023-02-14
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2023.162228
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Environmental monitoring and exposure science dataset to calculate ingestion and inhalation of metal(loid)s through preschool gardening

    Manjón, Iliana / Ramírez-Andreotta, Mónica D. / Sáez, A. Eduardo / Root, Robert A. / Hild, Joanne / Janes, M. Katy / Alexander-Ozinskas, Annika

    Data in Brief. 2020 Apr., v. 29

    2020  

    Abstract: Metal(loid) contamination may pose an increased risk of exposure to children residing near legacy and active resource extraction sites. Children may be exposed to arsenic, cadmium, and/or lead by ingestion and/or inhalation while engaging in school or ... ...

    Abstract Metal(loid) contamination may pose an increased risk of exposure to children residing near legacy and active resource extraction sites. Children may be exposed to arsenic, cadmium, and/or lead by ingestion and/or inhalation while engaging in school or home outdoor activities via environmental media including water, soil, dust, and locally grown produce. It is thus critical to collect site-specific data to best assess these risks. This data article provides gastric and lung in-vitro bioaccessibility assay (IVBA) data, as well as environmental monitoring data for water, soil, dust, and garden produce collected from preschools (N = 4) in mining communities throughout Nevada County, California in 2018. Arsenic, cadmium, and lead concentrations in the aforementioned media and synthetic gastric and lung fluids were measured by inductively coupled plasma-mass spectrometry (ICP-MS). This dataset provides useful metal(loid) concentrations for future risk assessments for similar settings.
    Keywords arsenic ; bioavailability ; breathing ; cadmium ; data collection ; dust ; gardens ; ingestion ; lead ; lungs ; risk ; soil ; California
    Language English
    Dates of publication 2020-04
    Publishing place Elsevier Inc.
    Document type Article
    ZDB-ID 2786545-9
    ISSN 2352-3409
    ISSN 2352-3409
    DOI 10.1016/j.dib.2019.105050
    Database NAL-Catalogue (AGRICOLA)

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  3. Article: Ingestion and inhalation of metal(loid)s through preschool gardening: An exposure and risk assessment in legacy mining communities

    Manjón, Iliana / Ramírez-Andreotta, Mónica D / Sáez, A. Eduardo / Root, Robert A / Hild, Joanne / Janes, M. Katy / Alexander-Ozinskas, Annika

    Science of the total environment. 2020 May 20, v. 718

    2020  

    Abstract: Children residing in mining towns are potentially disproportionately exposed to metal(loid)s via ingestion and dust inhalation, thus, increasing their exposure when engaging in school or home gardening or playing outside. This citizen science study ... ...

    Abstract Children residing in mining towns are potentially disproportionately exposed to metal(loid)s via ingestion and dust inhalation, thus, increasing their exposure when engaging in school or home gardening or playing outside. This citizen science study assessed preschool children’s potential arsenic (As), cadmium (Cd), and lead (Pb) exposure via locally grown produce, water, incidental soil ingestion, and dust inhalation at four sites. Participants were trained to properly collect water, soil, and vegetable samples from their preschools in Nevada County, California. As, Cd, and Pb concentrations in irrigation sources did not exceed the U.S. EPA’s maximum contaminant and action levels. In general, garden and playground As and Pb soil concentrations exceeded the U.S. EPA Regional Screening Level, CalEPA Human Health Screening Level, and California Department of Toxic Substances Control Screening Level. In contrast, all Cd concentrations were below these recommended screening levels. Dust samples (<10 μm diameter) were generated from surface garden and playground soil collected at the preschools by a technique that simulated windblown dust. Soil and dust samples were then analyzed by in-vitro bioaccessibility assays using synthetic lung and gastric fluids to estimate the bioaccessible fraction of As, Cd, and Pb in the body. Metal(loid) exposure via grown produce revealed that lettuce, carrot, and cabbage grown in the preschool gardens accumulated a higher concentration of metal(loid) than those store-bought nation-wide. None of the vegetables exceeded the respective recommendation maximum levels for Cd and Pb set by the World Health Organization Codex Alimentarius Commission. The results of this study indicate that consumption of preschool-grown produce and incidental soil ingestion were major contributors to preschool-aged children’s exposure to As, Cd, and Pb. Traditionally, this level of site- and age-specific assessment and analyses does not occur at contaminated sites. The results of this holistic risk assessment can inform future risk assessment and public health interventions related to childhood metal(loid) exposures.
    Keywords Codex Alimentarius ; United States Environmental Protection Agency ; World Health Organization ; arsenic ; bioavailability ; cabbage ; cadmium ; carrots ; childhood ; dust ; gardens ; gastric juice ; geophagia ; home gardening ; human health ; inhalation exposure ; irrigation ; lead ; lettuce ; lungs ; mining ; oral exposure ; preschool children ; preschools ; public health ; risk assessment ; screening ; soil ; towns ; toxic substances ; California
    Language English
    Dates of publication 2020-0520
    Publishing place Elsevier B.V.
    Document type Article
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2019.134639
    Database NAL-Catalogue (AGRICOLA)

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  4. Article ; Online: Environmental monitoring and exposure science dataset to calculate ingestion and inhalation of metal(loid)s through preschool gardening.

    Manjón, Iliana / Ramírez-Andreotta, Mónica D / Sáez, A Eduardo / Root, Robert A / Hild, Joanne / Janes, M Katy / Alexander-Ozinskas, Annika

    Data in brief

    2019  Volume 29, Page(s) 105050

    Abstract: Metal(loid) contamination may pose an increased risk of exposure to children residing near legacy and active resource extraction sites. Children may be exposed to arsenic, cadmium, and/or lead by ingestion and/or inhalation while engaging in school or ... ...

    Abstract Metal(loid) contamination may pose an increased risk of exposure to children residing near legacy and active resource extraction sites. Children may be exposed to arsenic, cadmium, and/or lead by ingestion and/or inhalation while engaging in school or home outdoor activities via environmental media including water, soil, dust, and locally grown produce. It is thus critical to collect site-specific data to best assess these risks. This data article provides gastric and lung
    Language English
    Publishing date 2019-12-31
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2786545-9
    ISSN 2352-3409 ; 2352-3409
    ISSN (online) 2352-3409
    ISSN 2352-3409
    DOI 10.1016/j.dib.2019.105050
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Ingestion and inhalation of metal(loid)s through preschool gardening: An exposure and risk assessment in legacy mining communities.

    Manjón, Iliana / Ramírez-Andreotta, Mónica D / Sáez, A Eduardo / Root, Robert A / Hild, Joanne / Janes, M Katy / Alexander-Ozinskas, Annika

    The Science of the total environment

    2019  Volume 718, Page(s) 134639

    Abstract: Children residing in mining towns are potentially disproportionately exposed to metal(loid)s via ingestion and dust inhalation, thus, increasing their exposure when engaging in school or home gardening or playing outside. This citizen science study ... ...

    Abstract Children residing in mining towns are potentially disproportionately exposed to metal(loid)s via ingestion and dust inhalation, thus, increasing their exposure when engaging in school or home gardening or playing outside. This citizen science study assessed preschool children's potential arsenic (As), cadmium (Cd), and lead (Pb) exposure via locally grown produce, water, incidental soil ingestion, and dust inhalation at four sites. Participants were trained to properly collect water, soil, and vegetable samples from their preschools in Nevada County, California. As, Cd, and Pb concentrations in irrigation sources did not exceed the U.S. EPA's maximum contaminant and action levels. In general, garden and playground As and Pb soil concentrations exceeded the U.S. EPA Regional Screening Level, CalEPA Human Health Screening Level, and California Department of Toxic Substances Control Screening Level. In contrast, all Cd concentrations were below these recommended screening levels. Dust samples (<10 μm diameter) were generated from surface garden and playground soil collected at the preschools by a technique that simulated windblown dust. Soil and dust samples were then analyzed by in-vitro bioaccessibility assays using synthetic lung and gastric fluids to estimate the bioaccessible fraction of As, Cd, and Pb in the body. Metal(loid) exposure via grown produce revealed that lettuce, carrot, and cabbage grown in the preschool gardens accumulated a higher concentration of metal(loid) than those store-bought nation-wide. None of the vegetables exceeded the respective recommendation maximum levels for Cd and Pb set by the World Health Organization Codex Alimentarius Commission. The results of this study indicate that consumption of preschool-grown produce and incidental soil ingestion were major contributors to preschool-aged children's exposure to As, Cd, and Pb. Traditionally, this level of site- and age-specific assessment and analyses does not occur at contaminated sites. The results of this holistic risk assessment can inform future risk assessment and public health interventions related to childhood metal(loid) exposures.
    MeSH term(s) California ; Child ; Child, Preschool ; Cities ; Gardening ; Humans ; Infant ; Metals ; Risk Assessment ; Soil Pollutants
    Chemical Substances Metals ; Soil Pollutants
    Language English
    Publishing date 2019-11-22
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2019.134639
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Heavy Metals in California Women Living in a Gold Mining-Impacted Community.

    Von Behren, Julie / Liu, Ruiling / Sellen, Jane / Duffy, Christine N / Gajek, Ryszard / Choe, Key-Young / DeGuzman, Josephine / Janes, M Katy / Hild, Joanne / Reynolds, Peggy

    International journal of environmental research and public health

    2019  Volume 16, Issue 13

    Abstract: Gold mining activities occurred throughout the foothills of the Sierra Nevada Mountains in California, leaving behind persistent toxic contaminants in the soil, dust, and water that include arsenic and cadmium. Despite a high level of concern among local ...

    Abstract Gold mining activities occurred throughout the foothills of the Sierra Nevada Mountains in California, leaving behind persistent toxic contaminants in the soil, dust, and water that include arsenic and cadmium. Despite a high level of concern among local residents about potential exposure and high breast cancer rates, no biomonitoring data has been collected to evaluate the levels of heavy metals. We conducted a study to characterize the urinary levels of heavy metals among women in this region by working with the community in Nevada County. Sixty women provided urine samples and completed a questionnaire. We examined levels of arsenic, cadmium, and other metals in relation to the length of residency in the area, age, dietary factors, recreational activities, and smoking. We compared urinary metal levels in participants to levels in the United States National Health and Nutrition Examination Survey (NHANES). Overall, study participants had higher urinary levels of arsenic than women in the national sample. Cadmium levels were similar to the national average, although they were elevated in women ≥35 years who had lived in the region for 10 years or more. Arsenic levels were higher among women who smoked, ate fish, ate home-grown produce, and who reported frequent hiking or trail running, although these differences were not statistically significant. This study established a successful community-research partnership, which facilitated community dialogue about possible human health consequences of living in a mining-impacted area.
    MeSH term(s) Adult ; Age Factors ; Aged ; Aged, 80 and over ; Arsenic/urine ; Cadmium/urine ; California ; Diet ; Environmental Monitoring ; Female ; Gold ; Health Surveys ; Humans ; Leisure Activities ; Metals, Heavy/urine ; Middle Aged ; Mining/statistics & numerical data ; Nutrition Surveys ; Smoking/epidemiology ; Young Adult
    Chemical Substances Metals, Heavy ; Cadmium (00BH33GNGH) ; Gold (7440-57-5) ; Arsenic (N712M78A8G)
    Language English
    Publishing date 2019-06-26
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1660-4601
    ISSN (online) 1660-4601
    DOI 10.3390/ijerph16132252
    Database MEDical Literature Analysis and Retrieval System OnLINE

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