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  1. Book: Summitt's fundamentals of operative dentistry

    Hilton, Thomas J. / Ferracane, Jack L. / Broome, James C.

    a contemporary approach

    2013  

    Title variant Fundamentals of operative dentistry
    Author's details ed. by Thomas J. Hilton ; Jack L. Ferracane ; James C. Broome
    Keywords Dentistry, Operative / methods ; Dentistry, Operative / instrumentation ; Dental Materials / therapeutic use ; Dental Prosthesis ; Dental Caries / therapy ; Esthetics, Dental
    Language English
    Size XII, 600 S. : zahlr. Ill., graph. Darst.
    Edition 4. ed.
    Publisher Quintessence Publ
    Publishing place Chicago u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT017707478
    ISBN 978-0-86715-528-0 ; 0-86715-528-0
    Database Catalogue ZB MED Medicine, Health

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  2. Article ; Online: Lessons learned from the Cracked Tooth Registry: A 3-year clinical study in the Nation's Network.

    Ferracane, Jack L / Hilton, Thomas J / Funkhouser, Ellen

    Journal of the American Dental Association (1939)

    2023  Volume 154, Issue 3, Page(s) 235–244

    Abstract: Background: This article reviews the most salient lessons learned from a large, multisite, 3-year observational study of posterior teeth with cracks conducted by The National Dental Practice-Based Research Network.: Types of studies reviewed: Eight ... ...

    Abstract Background: This article reviews the most salient lessons learned from a large, multisite, 3-year observational study of posterior teeth with cracks conducted by The National Dental Practice-Based Research Network.
    Types of studies reviewed: Eight articles published over a 6-year period (2017-2022) describing clinical characteristics of posterior teeth with cracks and their treatment and outcomes are reviewed and discussed to answer 3 common questions faced by oral health care clinicians: Which cracked teeth will get worse? When should practitioners intervene? What is the best treatment?
    Results: Although cracks in teeth are prevalent, few will fracture (3%) or show crack progression in 3 years (12%). Characteristics that guide the clinician to treatment include active caries, biting pain, and to a lesser degree, having a crack detectable with an explorer, connecting with a restoration, or blocking transilluminated light; the main treatment chosen is a complete crown. Of those teeth treated (36%), few (14%) will need retreatment but will still survive, despite having an internal crack as well.
    Conclusions and practical implications: Although cracked teeth often pose a dilemma to clinicians, clincians are generally good at deciding which teeth to treat and when and which to monitor.
    MeSH term(s) Humans ; Cracked Tooth Syndrome ; Dental Caries ; Fractures, Bone ; Crowns ; Oral Health ; Observational Studies as Topic
    Language English
    Publishing date 2023-01-21
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 220622-5
    ISSN 1943-4723 ; 0002-8177 ; 1048-6364
    ISSN (online) 1943-4723
    ISSN 0002-8177 ; 1048-6364
    DOI 10.1016/j.adaj.2022.11.020
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Sealers, Liners, and Bases.

    Hilton, Thomas J

    Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.

    2016  Volume 28, Issue 3, Page(s) 141–143

    MeSH term(s) Dental Cavity Lining ; Humans ; Pit and Fissure Sealants
    Chemical Substances Pit and Fissure Sealants
    Language English
    Publishing date 2016-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 2043146-6
    ISSN 1708-8240 ; 1496-4155
    ISSN (online) 1708-8240
    ISSN 1496-4155
    DOI 10.1111/jerd.12218
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Authors' response.

    Hilton, Thomas / Ferracane, Jack L / Funkhouser, Ellen

    Journal of the American Dental Association (1939)

    2021  Volume 152, Issue 6, Page(s) 424

    MeSH term(s) Humans ; Tooth Fractures
    Language English
    Publishing date 2021-05-28
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 220622-5
    ISSN 1943-4723 ; 0002-8177 ; 1048-6364
    ISSN (online) 1943-4723
    ISSN 0002-8177 ; 1048-6364
    DOI 10.1016/j.adaj.2021.04.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Filling the gap: a series of 3D-printed titanium truss cages for the management of large, lower limb bone defects in a developing country setting.

    Gamieldien, Hammaad / Ferreira, Nando / Birkholtz, Franz Friedrich / Hilton, Thomas / Campbell, Neil / Laubscher, Maritz

    European journal of orthopaedic surgery & traumatology : orthopedie traumatologie

    2022  Volume 33, Issue 3, Page(s) 497–505

    Abstract: Introduction: Large segmental long bone defects are notoriously difficult to manage. Treatment is resource-intensive due to the complexity, cost, and specialized skills required. Truss designs are known for their triangular shapes organized in web ... ...

    Abstract Introduction: Large segmental long bone defects are notoriously difficult to manage. Treatment is resource-intensive due to the complexity, cost, and specialized skills required. Truss designs are known for their triangular shapes organized in web configurations. This allows for maximal mechanical strength, the least mass, and a lattice that can be filled with bone graft. Using a truss cage combined with contemporary internal fixation provides immediate stability for bone ingrowth and long-term potential union. The implant is designed using virtual 3D modelling of the patient's bone defect based on a CT scan. The truss cage can be used in a staged procedure combined with Masquelet's induced membrane technique. This study aims to review the outcomes of patient-specific, locally designed 3D titanium truss cages packed with cancellous autograft in treating segmental, long bone defects in the lower limb in a developing country setting.
    Methods: This retrospective series reviewed cases performed at various institutions between January 2019 and March 2022. Parameters assessed included patient demographics, size and location of the defect, time to clinical and radiological union and complications.
    Results: Nine cases were included for review, with a mean age of 36 years (range 19-52). Defects ranged from 60 to 205 mm, and eight cases were staged procedures. Eight cases used intramedullary reamings as bone graft. Contemporary intramedullary nails were used for fixation in all cases. No peri- or post-operative complications occurred. All cases progressed to functional union.
    Conclusion: 3D-printed titanium truss cages combined with bone graft appear to be an effective treatment of large bone defects in the lower limb in a developing country setting in the short term. No complications were encountered, but longer follow-up is needed before definitive recommendations can be made.
    Level of evidence: Level IV (retrospective case series).
    MeSH term(s) Humans ; Young Adult ; Adult ; Middle Aged ; Titanium ; Retrospective Studies ; Developing Countries ; Lower Extremity ; Printing, Three-Dimensional
    Chemical Substances Titanium (D1JT611TNE)
    Language English
    Publishing date 2022-11-16
    Publishing country France
    Document type Journal Article
    ZDB-ID 1231084-0
    ISSN 1432-1068 ; 1633-8065 ; 0948-4817 ; 0940-3264
    ISSN (online) 1432-1068
    ISSN 1633-8065 ; 0948-4817 ; 0940-3264
    DOI 10.1007/s00590-022-03434-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Developing an antibiogram for empiric antibiotic prescribing for adult non-spinal orthopaedic infections in a developing world setting.

    Arakkal, Ashley / Centner, Chad M / Hilton, Thomas / Nortje, Marc / Held, Michael / Roche, Stephen / Brink, Adrian J / Mendelson, Marc / Laubscher, Maritz

    European journal of orthopaedic surgery & traumatology : orthopedie traumatologie

    2023  Volume 34, Issue 2, Page(s) 815–821

    Abstract: Purpose: Empiric antibiotic strategies in the treatment of fracture-related infections, chronic osteomyelitis, prosthetic joint infection, and septic arthritis should be based on local microbiological antibiograms. This study aims to describe the ... ...

    Abstract Purpose: Empiric antibiotic strategies in the treatment of fracture-related infections, chronic osteomyelitis, prosthetic joint infection, and septic arthritis should be based on local microbiological antibiograms. This study aims to describe the microbiology and review the antibiogram profiles of bacterial isolates from patients undergoing surgical treatment for non-spinal orthopaedic infections, to identify the most appropriate empiric antibiotic strategy.
    Methods: A retrospective review was performed of all cases of non-spinal orthopaedic infections treated surgically from 1 January 2018 to 31 December 2018. The National Health Laboratory Service microbiology database was used to identify all intra-operative microbiological specimens obtained from orthopaedic patients, and data were correlated with the orthopaedic surgical database. Cases were divided into fracture-related infections, chronic osteomyelitis, prosthetic joint infection, and septic arthritis. Antibiotic susceptibility data were used to predict the efficacy of different empiric antibiotic regimens.
    Results: A total of 107 cases were included in the study; 184 organisms were cultured. Overall, the most common organism cultured was Staphylococcus aureus (25%) followed by Acinetobacter baumannii (9%), Enterococcus faecalis (7%) and Enterobacter cloacae (5%). Across all categories the oral antibiotic combination with the highest effectiveness (81%) would have been a combination of co-trimoxazole, ciprofloxacin and amoxicillin. The most effective intravenous antibiotic combination would have been either piperacillin-tazobactam, amikacin and vancomycin or meropenem and vancomycin; 90% of tested isolates were susceptible to either of these combinations.
    Conclusion: Antibiogram profiles can serve to guide to empiric antibiotic choice in the management of different categories of non-spinal orthopaedic infections.
    MeSH term(s) Adult ; Humans ; Anti-Bacterial Agents/therapeutic use ; Vancomycin ; Orthopedics ; Osteomyelitis/drug therapy ; Arthritis, Infectious/drug therapy ; Microbial Sensitivity Tests ; Retrospective Studies
    Chemical Substances Anti-Bacterial Agents ; Vancomycin (6Q205EH1VU)
    Language English
    Publishing date 2023-09-15
    Publishing country France
    Document type Journal Article
    ZDB-ID 1231084-0
    ISSN 1432-1068 ; 1633-8065 ; 0948-4817 ; 0940-3264
    ISSN (online) 1432-1068
    ISSN 1633-8065 ; 0948-4817 ; 0940-3264
    DOI 10.1007/s00590-023-03718-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: The promise of PROMIS(®) for addiction.

    Hilton, Thomas F

    Drug and alcohol dependence

    2012  Volume 119, Issue 3, Page(s) 229–234

    Abstract: The field of addiction treatment has a measurement problem that pervades efforts to help patients achieve self-sustainable recovery. The impact of using older measurement technology has increased the measurement burden on both service providers and ... ...

    Abstract The field of addiction treatment has a measurement problem that pervades efforts to help patients achieve self-sustainable recovery. The impact of using older measurement technology has increased the measurement burden on both service providers and patients, while at the same time limiting the scope and frequency of measurement. The resulting burden can affect provider performance, patient access, and addiction recovery. This paper underscores the need for applying modern measurement theory techniques to reduce the measurement burden currently affecting most if not all major aspects of treatment and recovery. It is currently possible to obtain information more precisely, over a broad spectrum of recovery-oriented domains, faster and at lower cost than current measurement practices allow. However, a persistent research effort will be necessary to achieve that goal.
    MeSH term(s) Cost of Illness ; Decision Making, Computer-Assisted ; Humans ; Self Report/standards ; Substance-Related Disorders/diagnosis ; Substance-Related Disorders/epidemiology ; Substance-Related Disorders/therapy ; Treatment Outcome
    Language English
    Publishing date 2012-01-12
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 519918-9
    ISSN 1879-0046 ; 0376-8716
    ISSN (online) 1879-0046
    ISSN 0376-8716
    DOI 10.1016/j.drugalcdep.2011.09.031
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Life Expectancy After Treatment of Metastatic Bone Disease: An International Trend Analysis.

    Rogers, Davis L / Raad, Micheal / Rivera, Julio A / Wedin, Rikard / Laitinen, Minna / Sørensen, Michala S / Petersen, Michael M / Hilton, Thomas / Morris, Carol D / Levin, Adam S / Forsberg, Jonathan A

    The Journal of the American Academy of Orthopaedic Surgeons

    2024  Volume 32, Issue 6, Page(s) e293–e301

    Abstract: Introduction: The decision to treat metastatic bone disease (MBD) surgically depends in part on patient life expectancy. We are unaware of an international analysis of how life expectancy among these patients has changed over time. Therefore, we asked ( ... ...

    Abstract Introduction: The decision to treat metastatic bone disease (MBD) surgically depends in part on patient life expectancy. We are unaware of an international analysis of how life expectancy among these patients has changed over time. Therefore, we asked (1) how has the life expectancy for patients treated for MBD changed over time, and (2) which, if any, of the common primary cancer types are associated with longer survival after treatment of MBD?
    Methods: We reviewed data collected from 2000 to 2022 in an international MBD database, as well as data used for survival model validation. We included 3,353 adults who underwent surgery and/or radiation. No patients were excluded. Patients were grouped by treatment date into period 1 (2000 to 2009), period 2 (2010 to 2019), and period 3 (2020 to 2022). Cumulative survival was portrayed using Kaplan-Meier curves; log-rank tests were used to determine significance at P < 0.05. Subgroup analyses by primary cancer diagnosis were performed.
    Results: Median survival in period 2 was longer than in period 1 ( P < 0.001). Median survival (at which point 50% of patients survived) had not been reached for period 3. Median survival was longer in period 2 for all cancer types ( P < 0.001) except thyroid. Only lung cancer reached median survival in period 3, which was longer compared with periods 1 and 2 ( P < 0.001). Slow-growth, moderate-growth, and rapid-growth tumors all demonstrated longer median survival from period 1 to period 2; only rapid-growth tumors reached median survival for period 3, which was longer compared with periods 1 and 2 ( P < 0.001).
    Discussion: Median duration of survival after treatment of MBD has increased, which was a consistent finding in nearly all cancer types. Longer survival is likely attributable to improvements in both medical and surgical treatments. As life expectancy for patients with MBD increases, surgical methods should be selected with this in mind.
    Level of evidence: VI.
    MeSH term(s) Adult ; Humans ; Bone Diseases ; Bone Neoplasms/surgery ; Life Expectancy ; Lung Neoplasms ; Retrospective Studies
    Language English
    Publishing date 2024-01-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1200524-1
    ISSN 1940-5480 ; 1067-151X
    ISSN (online) 1940-5480
    ISSN 1067-151X
    DOI 10.5435/JAAOS-D-23-00332
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Polymerization stress--is it clinically meaningful?

    Ferracane, Jack L / Hilton, Thomas J

    Dental materials : official publication of the Academy of Dental Materials

    2016  Volume 32, Issue 1, Page(s) 1–10

    Abstract: Objectives: The objective of this article is to discuss the evidence for polymerization shrinkage and shrinkage stress of dental composite restoratives in terms of its potential relevance to the clinical situation: Methods: Articles relating to the ... ...

    Abstract Objectives: The objective of this article is to discuss the evidence for polymerization shrinkage and shrinkage stress of dental composite restoratives in terms of its potential relevance to the clinical situation
    Methods: Articles relating to the issue of polymerization contraction stress generation in dental composite materials, and the factors that influence it, were reviewed and included. Particular attention was paid to evidence derived from clinical studies. Articles were identified through PubMed and through the bibliographies of other articles.
    Results: There is extensive evidence for the presence of polymerization contraction stress in dental composites, as well as evidence for its deleterious effects, which include marginal leakage, gap formation, cuspal deflection, tooth cracking, reduced bond strength and lowered mechanical properties of the restorative. There is little, if any, direct evidence for the clinical effect of these contraction stresses. No study has directly established a link between these stresses and enhanced postoperative sensitivity or recurrent caries, for example. However, the concern over these stresses and the manner in which they influence the placement of current composite materials demonstrates that they are considered to be very important.
    Conclusion: Though no direct evidence exists to prove that the generation of contraction stress in dental composite restorations causes reduced clinical longevity, the indirect evidence from numerous in vitro studies and the concern over controlling their effects proves that they are clinically relevant.
    MeSH term(s) Composite Resins/chemistry ; Dental Restoration, Permanent ; Elasticity ; Hardness ; Materials Testing ; Polymerization ; Tensile Strength
    Chemical Substances Composite Resins
    Language English
    Publishing date 2016-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 605995-8
    ISSN 1879-0097 ; 0109-5641
    ISSN (online) 1879-0097
    ISSN 0109-5641
    DOI 10.1016/j.dental.2015.06.020
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: The Key to Individualized Addiction Treatment is Comprehensive Assessment and Monitoring of Symptoms and Behavioral Change.

    Hilton, Thomas F / Pilkonis, Paul A

    Behavioral sciences (Basel, Switzerland)

    2015  Volume 5, Issue 4, Page(s) 477–495

    Abstract: Modern health services now strive for individualized treatment. This approach has been enabled by the increase in knowledge derived from neuroscience and genomics. Substance use disorders are no exception to individualized treatment even though there are ...

    Abstract Modern health services now strive for individualized treatment. This approach has been enabled by the increase in knowledge derived from neuroscience and genomics. Substance use disorders are no exception to individualized treatment even though there are no gene-specific medications yet available. What is available is the ability to quickly and precisely assess and monitor biopsychosocial variables known to vary during addiction recovery and which place addicts at increased risk of relapse. Monitoring a broad spectrum of biopsychosocial health enables providers to address diverse genome-specific changes that might trigger withdrawal from treatment or recovery relapse in time to prevent that from occurring. This paper describes modern measurement tools contained in the NIH Patient-Reported Outcomes Measurement Information System (PROMIS) and the NIH Toolbox and suggests how they might be applied to support recovery from alcohol and other substance use disorders in both pharmacological and abstinence-oriented modalities of care.
    Language English
    Publishing date 2015-10-30
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2651997-5
    ISSN 2076-328X
    ISSN 2076-328X
    DOI 10.3390/bs5040477
    Database MEDical Literature Analysis and Retrieval System OnLINE

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