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  1. Article ; Online: Quality improvement initiative approach to decrease the unindicated usage of antibiotics in a neonatal intensive care unit of a tertiary care teaching hospital in Hyderabad, India

    Kalyan Chakravarthy Konda / Himabindu Singh / Alimelu Madireddy / Megha Mala Rao Poodari

    BMJ Open Quality, Vol 10, Iss Suppl

    2021  Volume 1

    Keywords Medicine (General) ; R5-920
    Language English
    Publishing date 2021-08-01T00:00:00Z
    Publisher BMJ Publishing Group
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Supporting Immunization Uptake during a Pandemic, Using Remote Phone Call Intervention among Babies Discharged from a Special Neonatal Care Unit (SNCU) in South India

    Seema Murthy / Meenal Sawant / Sahana Sadholalu Doreswamy / Sateesh Chandra Pothula / Shirley Du Yan / Tanmay Singh Pathani / Deepali Thakur / Srikrishna Rajarama Sastry Vemuri / Sanjeev Upadhyaya / Shahed Alam / Madireddy Alimelu / Himabindu Singh

    Vaccines, Vol 10, Iss 507, p

    2022  Volume 507

    Abstract: COVID-19 has impacted children’s immunization rates, putting the lives of children at risk. The present study assesses the impact of phone-call counseling, on immunization uptake during the pandemic. Families of babies discharged from the SNCUs in six ... ...

    Abstract COVID-19 has impacted children’s immunization rates, putting the lives of children at risk. The present study assesses the impact of phone-call counseling, on immunization uptake during the pandemic. Families of babies discharged from the SNCUs in six government centers in three South Indian states were recruited. Calls were made 10 days after the immunization due date. Missed vaccinees were counseled and followed up on 7 and 15 days. Of 2313 contacted, 2097 completed the survey. Respondents were mostly mothers (88.2%), poor (67.5%), and had secondary level education (37.4%). Vaccinations were missed due to the baby’s poor health (64.1%), COVID-19 related concerns (32.6%), and lack of awareness (16.8%). At the end of the intervention, the immunization uptake increased from 65.2% to 88.2%. Phone-call intervention can safely support immunization and lower the burden on health workers.
    Keywords SNCU babies ; COVID ; immunization uptake ; Medicine ; R
    Language English
    Publishing date 2022-03-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Effect of Nutrition Supplementation in Children Living with HIV at ART Centre.

    Thakur, Himabindu Singh / Gottapu, Geetha Srivalliswari / Kadali, Sai Prasad / Kulkarni, Bharati / Mamidi, Raja Sriswan

    Indian journal of pediatrics

    2016  Volume 83, Issue 3, Page(s) 232–237

    Abstract: Objective: To assess the benefits of nutrition supplementation in children living with HIV (CLHIV).: Methods: A prospective observational study was carried out at antiretroviral therapy (ART)/pediatric centre of excellence (PCOE), Niloufer hospital ... ...

    Abstract Objective: To assess the benefits of nutrition supplementation in children living with HIV (CLHIV).
    Methods: A prospective observational study was carried out at antiretroviral therapy (ART)/pediatric centre of excellence (PCOE), Niloufer hospital for a period of one year in CLHIV (N = 164) aged 1 to 18 y referred to ART/PCOE. Nutrition supplementation was given in the form of Ready to Use Food (About 350 kcal and 12 g of protein per day) supplementation to assess improvement in Height for age Z (HAZ), Weight for Age Z (WAZ), Weight for Height Z (WHZ) and Body Mass Index for age Z (BMIZ) scores over a period of one year.
    Results: At baseline, 65.5 % and 57.5 % of children below and above 5 y respectively were stunted. 24.1 % and 45.3 % children below and above 5 y respectively were wasted/thin (as assessed by BMI for age). Mean BMIZ score significantly improved in both the age groups (0.96 Z score, P < 0.001) in below and above 5 (0.37 Z score, P < 0.001) respectively at the end of 12 mo. Mean HAZ score also significantly improved in children above 5 y (0.09 Z score, P < 0.05) with non-significant improvement below 5 y (0.14 Z score, P < 0.57) by the end of 12 mo.
    Conclusions: Nutrition supplementation over one year resulted in moderate improvement in the nutritional status of CLHIV. However, it is unclear, whether the improvement in nutritional status was due to regular visits to ART centre that may have resulted in better adherence to treatment or an additional benefit of nutrition intervention. This warrants a well-designed randomized controlled trial to examine the benefits of nutrition supplementation in CLHIV attending ART centre.
    MeSH term(s) Adolescent ; Anti-Retroviral Agents/therapeutic use ; Body Height ; Body Mass Index ; Body Weight ; Child ; Child, Preschool ; Dietary Supplements ; Female ; HIV Infections/drug therapy ; Humans ; Infant ; Male ; Nutritional Status/drug effects ; Prospective Studies ; Treatment Outcome
    Chemical Substances Anti-Retroviral Agents
    Language English
    Publishing date 2016-03
    Publishing country India
    Document type Journal Article ; Observational Study
    ZDB-ID 218231-2
    ISSN 0973-7693 ; 0019-5456
    ISSN (online) 0973-7693
    ISSN 0019-5456
    DOI 10.1007/s12098-015-1873-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Burden of congenital rubella syndrome (CRS) in India based on data from cross-sectional serosurveys, 2017 and 2019-20.

    Devika Shanmugasundaram / Shally Awasthi / Bhagirathi Dwibedi / S Geetha / Manish Jain / Shikha Malik / Bhupeshwari Patel / Himabindu Singh / Shalini Tripathi / Rajlakshmi Viswanathan / Anjoo Agarwal / Rajeswari Bonu / Shuchi Jain / Saubhagya Kumar Jena / J Priyasree / K Pushpalatha / Syed Ali / Debasis Biswas / Amita Jain /
    Rahul Narang / Sudha Madhuri / Suji George / Ojas Kaduskar / G Kiruthika / R Sabarinathan / Gajanan Sapakal / Nivedita Gupta / Manoj V Murhekar

    PLoS Neglected Tropical Diseases, Vol 15, Iss 7, p e

    2021  Volume 0009608

    Abstract: Background India has set a goal to eliminate measles and rubella/Congenital Rubella Syndrome (CRS) by 2023. Towards this goal, India conducted nationwide supplementary immunization activity (SIA) with measles-rubella containing vaccine (MRCV) targeting ... ...

    Abstract Background India has set a goal to eliminate measles and rubella/Congenital Rubella Syndrome (CRS) by 2023. Towards this goal, India conducted nationwide supplementary immunization activity (SIA) with measles-rubella containing vaccine (MRCV) targeting children aged between 9 months to <15 years and established a hospital-based sentinel surveillance for CRS. Reliable data about incidence of CRS is necessary to monitor progress towards the elimination goal. Methods We conducted serosurveys in 2019-20 among pregnant women attending antenatal clinics of 6 hospitals, which were also sentinel sites for CRS surveillance, to estimate the prevalence of IgG antibodies against rubella. We systematically sampled 1800 women attending antenatal clinics and tested their sera for IgG antibodies against rubella. We used rubella seroprevalence data from the current survey and the survey conducted in 2017 among antenatal women from another 6 CRS surveillance sites to construct a catalytic models to estimate the incidence and burden of CRS. Result The seroprevalence of rubella antibodies was 82.3% (95% CI: 80.4-84.0). Rubella seropositivity did not differ by age group and educational status. Based on the constant and age-dependent force of infection models, we estimated that the annual incidence of CRS in India was 225.58 per 100,000 live births (95% CI: 217.49-232.41) and 65.47 per 100,000 live births (95% CI: 41.60-104.16) respectively. This translated to an estimated 14,520 (95% CI: 9,225-23,100) and 50,028 (95% CI: 48,234-51,543) infants with CRS every year based on age-dependent and constant force of infection models respectively. Conclusions Our findings indicated that about one fifth of women in the reproductive age group in India were susceptible for rubella. The estimates of CRS incidence will serve as a baseline to monitor the impact of MRCV SIAs, as well progress towards the elimination goal of rubella/CRS.
    Keywords Arctic medicine. Tropical medicine ; RC955-962 ; Public aspects of medicine ; RA1-1270
    Subject code 120
    Language English
    Publishing date 2021-07-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Congenital rubella syndrome surveillance in India, 2016–21

    Devika Shanmugasundaram / Sanjay Verma / Kuldeep Singh / Bhagirathi Dwibedi / Shally Awasthi / S. Mahantesh / Himabindu Singh / Sridhar Santhanam / Nivedita Mondal / Geetha S / Priya Sreenivasan / Shikha Malik / Manish Jain / Rajlakshmi Viswanathan / Shalini Tripathi / Bhupeshwari Patel / Gajanan Sapkal / R. Sabarinathan / Mini P. Singh /
    R.K. Ratho / Vijaylakshmi Nag / Ravishekhar Gadepalli / Tapas Kumar Som / Baijayantimala Mishra / Amita Jain / M. Ashok / Devara Sudha Madhuri / V Sudha Rani / Asha Mary Abraham / Deepa John / Rahul Dhodapkar / A. Syed Ali / Debasis Biswas / Deepashri Pratyeke / Ashish Bavdekar / Jayant Prakash / Varsha Singh / Nidhi Prasad / Jaydeb Ray / Agniva Majumdar / Shanta Dutta / Nivedita Gupta / Manoj Murhekar / Akhil Sharma / Aniruddha Ghosh / Arun Alexander / Arun Baranwal / Avinash Anantharaj / Adhisivam Bethou / Dolat S. Shekhawat / G. Kiruthika / Jagat Ram / Madhu Gupta / Mamatha Gowda / Manoj K Rohit / Nabaneeta Dash / Naveen Sankhyan / Nidhi Kaushal / Niranjan Hunasanahalli Shivanna / Nirupama Kasturi / P. Prem Kumar / Parul Chawla Gupta / Pradeep Kumar Gunasekaran / Pratibha Singh / Praveen Kumar / Sanjay Kumar Munjal / Siddharth Agarwal / Suhani Manasa / Suruchi Shukla / Urvashi Nehra / Valsan P Verghese / Varuna Vyas / Vikas Gupta

    Heliyon, Vol 9, Iss 5, Pp e15965- (2023)

    Analysis of five years surveillance data

    2023  

    Abstract: Background: In India, facility-based surveillance for congenital rubella syndrome (CRS) was initiated in 2016 to estimate the burden and monitor the progress made in rubella control. We analyzed the surveillance data for 2016–2021 from 14 sentinel sites ... ...

    Abstract Background: In India, facility-based surveillance for congenital rubella syndrome (CRS) was initiated in 2016 to estimate the burden and monitor the progress made in rubella control. We analyzed the surveillance data for 2016–2021 from 14 sentinel sites to describe the epidemiology of CRS. Method: We analyzed the surveillance data to describe the distribution of suspected and laboratory confirmed CRS patients by time, place and person characteristics. We compared clinical signs of laboratory confirmed CRS and discarded case-patients to find independent predictors of CRS using logistic regression analysis and developed a risk prediction model. Results: During 2016–21, surveillance sites enrolled 3940 suspected CRS case-patients (Age 3.5 months, SD: 3.5). About one-fifth (n = 813, 20.6%) were enrolled during newborn examination. Of the suspected CRS patients, 493 (12.5%) had laboratory evidence of rubella infection. The proportion of laboratory confirmed CRS cases declined from 26% in 2017 to 8.7% in 2021. Laboratory confirmed patients had higher odds of having hearing impairment (Odds ratio [OR] = 9.5, 95% confidence interval [CI]: 5.6–16.2), cataract (OR = 7.8, 95% CI: 5.4–11.2), pigmentary retinopathy (OR = 6.7, 95 CI: 3.3–13.6), structural heart defect with hearing impairment (OR = 3.8, 95% CI: 1.2–12.2) and glaucoma (OR = 3.1, 95% CI: 1.2–8.1). Nomogram, along with a web version, was developed. Conclusions: Rubella continues to be a significant public health issue in India. The declining trend of test positivity among suspected CRS case-patients needs to be monitored through continued surveillance in these sentinel sites.
    Keywords Congenital Rubella Syndrome ; Surveillance ; India ; Science (General) ; Q1-390 ; Social sciences (General) ; H1-99
    Subject code 120
    Language English
    Publishing date 2023-05-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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