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Article: Management strategies for antidepressant-related sexual dysfunction.

Lach, Frank / Bottemanne, Hugo / Hingray, Coraline / Papeta, Didier / Rousseau, Amélie / Javelot, Hervé

2024

Abstract: Antidepressant-related sexual dysfunction is one of the most frequently met adverse effects for individuals suffering from major depressive disorder. When primary prevention by non-pharmacological measures fails, empirical coping strategies might be ... ...

Abstract	Antidepressant-related sexual dysfunction is one of the most frequently met adverse effects for individuals suffering from major depressive disorder. When primary prevention by non-pharmacological measures fails, empirical coping strategies might be proposed. In this article, we present a brief overview of pharmacological strategies for antidepressant-related sexual dysfunction, considering antidepressants and conceivable corrective medications. We suggest dividing these strategies into three groups: (1) tapering (dose reduction, therapeutic window or short-term treatment interruption); (2) maintenance (focusing on spontaneous remission); (3) optimizing treatment (substitution for another antidepressant or addition of treatments to correct sexual side effects). Whichever strategy is selected, we encourage the clinician to propose the most adequate therapeutic option for the patient, while considering the efficacy and overall tolerance of the current antidepressant strategy, the affected phase of sexuality and patient preferences and gender. This summary is limited to antidepressant treatments and correctors marketed in France and aimed at a clinician reading to help manage patients suffering from antidepressant-induced sexual dysfunction.
Language	English
Publishing date	2024-02-03
Publishing country	France
Document type	Journal Article
ZDB-ID	214431-1
ISSN	0013-7006
ISSN	0013-7006
DOI	10.1016/j.encep.2023.11.025
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Article ; Online: Correction to: Functional neurologic disorders in an adult with propionic acidemia: a case report.

Tarrada, Alexis / Frismand-Kryloff, Solène / Hingray, Coraline

BMC psychiatry

2022 Volume 22, Issue 1, Page(s) 31

Language	English
Publishing date	2022-01-10
Publishing country	England
Document type	Published Erratum
ISSN	1471-244X
ISSN (online)	1471-244X
DOI	10.1186/s12888-021-03656-7
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Article: Crise non épileptique psychogène : le renouveau de l’abord des troubles de conversion.

Aupy, Jerome / Hingray, Coraline

La Revue du praticien

2019 Volume 69, Issue 2, Page(s) 214–218

Abstract: Non-epileptic psychogenic seizures: a renewal approach of conversion disorders. Psychogenic non-epileptic seizures (PNES) are characterized by a paroxystic modification of behaviour or consciousness that resemble to an epileptic seizure. They are ... ...

Title translation	Non-epileptic psychogenic seizures: a renewal approach of conversion disorders.
Abstract	Non-epileptic psychogenic seizures: a renewal approach of conversion disorders. Psychogenic non-epileptic seizures (PNES) are characterized by a paroxystic modification of behaviour or consciousness that resemble to an epileptic seizure. They are classified as dissociative or somatoform disorders. Their diagnostic remains difficult and the recording of a typical event through video-EEG is the gold standard. PNES are a symptom of the underlying disease related to disturbances in the management and regulation of emotions. Thus, the predisposing, the precipitating and the perpetuating factors must be evaluated carefully. A multidisciplinary diagnosis announcement is an essential and effective therapeutic step and treatment has to be adapted case by case.
MeSH term(s)	Conversion Disorder ; Electroencephalography ; Humans ; Psychophysiologic Disorders ; Seizures ; Somatoform Disorders
Language	French
Publishing date	2019-04-14
Publishing country	France
Document type	Journal Article ; Review
ZDB-ID	205365-2
ISSN	2101-017X ; 0035-2640
ISSN (online)	2101-017X
ISSN	0035-2640
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Article: Synthèse des principes et schémas de prise en charge dans les troubles neurologiques fonctionnels.

Carle-Toulemonde, Guilhem / Hingray, Coraline / Alaoui, Othman Mounir / Aybek, Selma / Mouchabac, Stéphane / Garcin, Béatrice

L'Encephale

2023 Volume 49, Issue 4S, Page(s) S49–S55

Abstract: After more than twenty years of academic research on functional neurological disorders (FND) throughout the world, a standardized care management strategy has emerged to allow a more adapted care offer to patients with FND, as close as possible to their ... ...

Title translation	Overview of care management principles in functional neurological disorders.
Abstract	After more than twenty years of academic research on functional neurological disorders (FND) throughout the world, a standardized care management strategy has emerged to allow a more adapted care offer to patients with FND, as close as possible to their experience and their needs. With regard to this special issue on FND in collaboration with L'Encéphale and at the initiative of the Neuropsychiatry section of the AFPBN (French Association of Biological Psychiatry and Neuropsychopharmacology), we would like to suggest a summary of all topics discussed in more detail in each article of this special issue, in order to facilitate its reading. We therefore cover the following themes: the initial contact with a patient with FND, the diagnostic process in favor of a positive diagnosis, the physiological, neural and psychological basis of FND, the diagnostic announcement (and its intangibles), the therapeutic patient education in FND, the general principles of therapeutic management through a personalized and multidisciplinary care program, and the validated therapeutic tools available according to the symptoms identified. This article is designed to be of broad interest on FND, supported by tables and figures showing the key points of all these steps, to keep an educational purpose at most. We hope that through this special issue, each health professional will be able to grasp this knowledge and this framework of care as easily and quickly as possible, in order to participate in the standardization of the care offer.
MeSH term(s)	Humans ; Conversion Disorder/diagnosis ; Conversion Disorder/psychology ; Conversion Disorder/therapy ; Educational Status ; Nervous System Diseases/diagnosis ; Nervous System Diseases/therapy
Language	French
Publishing date	2023-07-01
Publishing country	France
Document type	English Abstract ; Journal Article ; Review
ZDB-ID	214431-1
ISSN	0013-7006
ISSN	0013-7006
DOI	10.1016/j.encep.2023.06.007
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Article: Définitions, épidémiologie et démarche diagnostique clinique dans les troubles neurologiques fonctionnels.

Garcin, Béatrice / Roze, Emmanuel / Daubigney, Antoine / Carle-Toulemonde, Guilhem / Degos, Bertrand / Hingray, Coraline

L'Encephale

2023 Volume 49, Issue 4S, Page(s) S3–S8

Abstract: Functional neurological disorders (FND) are symptoms that can affect a variety of functions including motor, sensory and cognitive. These symptoms are genuinely experienced by the patient and are related to a functional disorder rather than a structural ... ...

Title translation	Diagnostic criteria, epidemiology and assessment of patients with functional neurological disorders.
Abstract	Functional neurological disorders (FND) are symptoms that can affect a variety of functions including motor, sensory and cognitive. These symptoms are genuinely experienced by the patient and are related to a functional disorder rather than a structural one. There is little epidemiological data on these disorders, but their frequency is well established in clinical practice, it is the second most frequent reason for consultation in Neurology. Despite of the frequency of the disorder, general practitioners and specialists are insufficiently trained in the disease, and patients often suffer from stigmatization and/or unnecessary investigations. It is therefore important to be aware of the diagnostic approach to FND, which mostly relies on positive clinical signs. Psychiatric evaluation can help with the characterization of predisposing, precipitating and perpetuating factors of the symptoms (according to the 3P biopsychosocial model related to FND), and guide their management. Finally, diagnosis explanation is a crucial step in the management of the disease, which can in itself have a therapeutic effect, and allow the patient to adhere to the treatments.
MeSH term(s)	Humans ; Nervous System Diseases/diagnosis ; Nervous System Diseases/epidemiology ; Conversion Disorder/diagnosis ; Conversion Disorder/epidemiology ; Conversion Disorder/psychology ; General Practitioners ; Referral and Consultation
Language	French
Publishing date	2023-07-01
Publishing country	France
Document type	English Abstract ; Journal Article
ZDB-ID	214431-1
ISSN	0013-7006
ISSN	0013-7006
DOI	10.1016/j.encep.2023.06.001
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Article ; Online: The latent factor structure and assessment of childbirth-related PTSD in fathers: Psychometric characteristics of the City Birth Trauma Scale-French version (partner version).

Sandoz, Vania / Lacroix, Alain / Jubin, Maria / Hingray, Coraline / El Hage, Wissam / Horsch, Antje

Psychological trauma : theory, research, practice and policy

2023 Volume 15, Issue 7, Page(s) 1145–1152

Abstract: Objective: There is no evidence on the latent structure of symptoms of childbirth-related posttraumatic stress disorder (CB-PTSD) in fathers and to date, no validated French instrument exists to measure CB-PTSD in partners, although the City Birth ... ...

Abstract	Objective: There is no evidence on the latent structure of symptoms of childbirth-related posttraumatic stress disorder (CB-PTSD) in fathers and to date, no validated French instrument exists to measure CB-PTSD in partners, although the City Birth Trauma Scale (partner version) (City BiTS (P)) was developed to measure such CB-PTSD symptoms. This study aimed to validate the French version of the City BiTS-P (City BiTS-F (P)) in partners attending childbirth and to examine its factor structure, reliability, and validity. Method: French-speaking fathers of 1-to-12-month-olds participated in this online cross-sectional survey ( Results: The four-factor model did not fit well the data, contrary to the two-factor model with birth-related symptoms (BRS) and general symptoms (GS). However, the bifactor model with a general factor and the BRS and GS provided the best fit to the data. High reliability (α = .88-.89), and good convergent and divergent validity were found. Fathers with a history of traumatic childbirth reported higher total and subscale scores. Discussion: Our findings provide evidence for the use of the City BiTS-F (P) as a reliable and validated tool to assess CB-PTSD symptoms in French-speaking partners. The use of the total score in addition to the BRS and GS subscale scores is warranted. (PsycInfo Database Record (c) 2023 APA, all rights reserved).
MeSH term(s)	Female ; Pregnancy ; Humans ; Stress Disorders, Post-Traumatic/diagnosis ; Psychometrics ; Reproducibility of Results ; Cross-Sectional Studies ; Delivery, Obstetric
Language	English
Publishing date	2023-01-23
Publishing country	United States
Document type	Journal Article
ZDB-ID	2497028-1
ISSN	1942-969X ; 1942-9681
ISSN (online)	1942-969X
ISSN	1942-9681
DOI	10.1037/tra0001407
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Article ; Online: Benefit of long-acting paliperidone in Huntington's disease: a case report.

Javelot, Hervé / Meyer, Mylène / Frismand, Solène / Hingray, Coraline

International clinical psychopharmacology

2021 Volume 36, Issue 2, Page(s) 101–103

Abstract: Through this brief report, we described our clinical considerations about the treatment of motor fluctuations and psychiatric comorbidities in Huntington's disease, for example, aggressiveness and obsessive-compulsive disorders. Indeed, as classical ... ...

Abstract	Through this brief report, we described our clinical considerations about the treatment of motor fluctuations and psychiatric comorbidities in Huntington's disease, for example, aggressiveness and obsessive-compulsive disorders. Indeed, as classical treatment, for example, olanzapine and risperidone, were inefficient to improve motor disorders in our patient, we postulated that motor fluctuations could be influenced by the pharmacokinetic profile of oral risperidone. So, in line with recent practice in schizophrenia, we proposed empirically paliperidone 1-month long-acting injections hypothesized to improve motor fluctuations, treatment so far reserved to Huntington's disease patients who are noncompliant to oral risperidone. Improvement was soon observed concerning motor fluctuations, but also aggressiveness, supporting our initial hypothesis.
MeSH term(s)	Delayed-Action Preparations ; Humans ; Huntington Disease/drug therapy ; Paliperidone Palmitate/therapeutic use ; Treatment Outcome
Chemical Substances	Delayed-Action Preparations ; Paliperidone Palmitate (R8P8USM8FR)
Language	English
Publishing date	2021-01-21
Publishing country	England
Document type	Case Reports
ZDB-ID	632837-4
ISSN	1473-5857 ; 0268-1315
ISSN (online)	1473-5857
ISSN	0268-1315
DOI	10.1097/YIC.0000000000000346
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Article ; Online: Functional neurologic disorders in an adult with propionic acidemia: a case report.

Tarrada, Alexis / Frismand-Kryloff, Solène / Hingray, Coraline

BMC psychiatry

2021 Volume 21, Issue 1, Page(s) 587

Abstract: Background: Inborn errors of metabolism are often characterized by various psychiatric syndromes. Previous studies tend to classify psychiatric manifestations into clinical entities. Among inborn errors of metabolism, propionic acidemia (PA) is a rare ... ...

Abstract	Background: Inborn errors of metabolism are often characterized by various psychiatric syndromes. Previous studies tend to classify psychiatric manifestations into clinical entities. Among inborn errors of metabolism, propionic acidemia (PA) is a rare inherited organic aciduria that leads to neurologic disabilities. Several studies in children with PA demonstrated that psychiatric disorders are associated to neurological symptoms. To our knowledge, no psychopathological description in adult with propionic acidemia is available. Case presentation: We aimed to compare the case of a 53-year-old woman with PA, to the previous psychiatric descriptions in children with PA and in adults with other inborn errors of metabolism. Our patient presented a large variety of signs: functional neurologic disorders, borderline personality traits (emotional dyregulation, dissociative and alexithymic trends, obsessive-compulsive disorders), occurring in a context of neurodevelopmental disorder. Conclusion: Clinical and paraclinical examinations are in favor of a mild mental retardation since childhood and disorders of behavior and personality without any definite psychiatric syndrome, as already described in other metabolic diseases (group 3). Nonetheless, further studies are needed to clarify the psychiatric alterations within adult patients with PA.
MeSH term(s)	Adult ; Child ; Female ; Humans ; Middle Aged ; Nervous System Diseases/complications ; Phenotype ; Propionic Acidemia/complications ; Propionic Acidemia/diagnosis ; Propionic Acidemia/genetics
Language	English
Publishing date	2021-11-22
Publishing country	England
Document type	Case Reports ; Journal Article
ISSN	1471-244X
ISSN (online)	1471-244X
DOI	10.1186/s12888-021-03596-2
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Article: Anxiety and Depression in Newly Diagnosed Epilepsy: A Matter of Psychological History?

Forthoffer, Natacha / Tarrada, Alexis / Brissart, Hélène / Maillard, Louis / Hingray, Coraline

Frontiers in neurology

2021 Volume 12, Page(s) 744377

Abstract: Purpose: ...

Abstract	Purpose:
Language	English
Publishing date	2021-10-05
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2564214-5
ISSN	1664-2295
ISSN	1664-2295
DOI	10.3389/fneur.2021.744377
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Article: Case Report: Atonic PNES Capture in fMRI.

Hologne, Emmanuelle / Hossu, Gabriela / Fantin, Luca / Braun, Marc / Husson, Cyril / Tyvaert, Louise / Hingray, Coraline

Frontiers in neurology

2022 Volume 13, Page(s) 803145

Abstract: Psychogenic Non-Epileptic Seizures (PNES) are a misunderstood and disabling pathology, characterized by a paroxysmal occurrence of clinical signs without the epileptic activity. Resting-state functional MRI (fMRI) studies in patients with PNES have shown ...

Abstract	Psychogenic Non-Epileptic Seizures (PNES) are a misunderstood and disabling pathology, characterized by a paroxysmal occurrence of clinical signs without the epileptic activity. Resting-state functional MRI (fMRI) studies in patients with PNES have shown abnormal functional connectivity of the resting-state networks, especially in the limbic and motor systems, and in the precuneus. However, the transient nature of PNES episodes prevents us from elucidating the underlying mechanisms of seizures. Here, we report the case of a patient who presented an atonic episode of PNES during a 3T fMRI session. The patient is a 23-year-old woman, suffering from post-traumatic stress disorder, with no neurological comorbidities. The preprocessing of the fMRI images involved realignment, co-registration, segmentation, normalization, denoising (PhysIO toolbox), and smoothing. The time boundary of the seizure was defined according to the patient's reports, and the seizure period was contrasted with the resting state period before the seizure. A whole-brain analysis showed significant activations (left inferior temporal gyrus, left temporo-occipital junction) and deactivations (right precuneus, right superior parietal lobule, right postcentral gyrus, bilateral lingual gyri, inferior occipital gyri, and cerebellar lobules; right insula in a sub-thresholded analysis). Activations and deactivations occurred in four cerebral networks: emotional processing, agency, self-perception, and dissociation. To our knowledge, this report is the first published case of functional MRI during PNES. These results could confirm the emotional and dissociative hypothesis of the physiopathology of PNES and highlight future targets for neuromodulation.
Language	English
Publishing date	2022-02-21
Publishing country	Switzerland
Document type	Case Reports
ZDB-ID	2564214-5
ISSN	1664-2295
ISSN	1664-2295
DOI	10.3389/fneur.2022.803145
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