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  1. Article: Tracheostomy for the pediatric patient with fibrodysplasia ossificans progressiva: a case report.

    Kobayashi, Megumi / Hirai, Misako / Suzuki, Makoto / Sasaki, Akira

    Surgical case reports

    2024  Volume 10, Issue 1, Page(s) 61

    Abstract: Background: Fibrodysplasia ossificans progressiva (FOP) is an extremely rare connective tissue disease characterized by subsequent ossification of skeletal muscles, tendons, ligaments, and other fibrous tissues. The ossification of these tissues ... ...

    Abstract Background: Fibrodysplasia ossificans progressiva (FOP) is an extremely rare connective tissue disease characterized by subsequent ossification of skeletal muscles, tendons, ligaments, and other fibrous tissues. The ossification of these tissues progresses during childhood and leads to limb and trunk deformities. Since any surgery may trigger subsequent ossification, it is relatively contraindicated for patients with FOP. In this report, we describe our experience in performing tracheostomy in a pediatric patient with FOP who developed a restrictive respiratory disorder due to progressive deformity of the trunk.
    Case presentation: A 12-year-old boy, diagnosed with FOP at the age of one, was referred for a tracheotomy after requiring 2 months of oral intubation and mechanical ventilation due to severe deformity-induced dyspnea. After changing from oral intubation to nasal intubation, we carefully considered the indications and benefits of tracheostomy in patients with FOP. Eventually, tracheostomy was successfully performed using our surgical design: creating a skin incision at the level of the cricoid cartilage that can always be identified, creating inverted U-shaped incision on the anterior tracheal wall to make a flap, and suturing the entire circumference of the tracheotomy and skin. One month after the surgery, he regained normal breathing and pronunciation and returned to school. The patient showed no unfavorable postoperative outcomes over a 4-year follow-up period.
    Conclusions: Tracheostomy in our pediatric case of FOP required careful perioperative management. However, it could effectively improve the patient's quality of life.
    Language English
    Publishing date 2024-03-15
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2809613-7
    ISSN 2198-7793
    ISSN 2198-7793
    DOI 10.1186/s40792-024-01864-3
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  2. Article ; Online: Positive C4d staining of the portal vein endothelium in the liver of patients with biliary atresia: a role of humoral immunity in ongoing liver fibrosis.

    Fujisawa, Sorahiko / Muraji, Toshihiro / Sakamoto, Naoya / Hosaka, Naoki / Matsuda, Satoshi / Kawakami, Hajime / Hirai, Misako / Yanai, Toshihiro

    Pediatric surgery international

    2014  Volume 30, Issue 9, Page(s) 877–881

    Abstract: Purpose: This study aimed to clarify the role of complement activation in fibrogenesis in BA.: Methods: In total, 27 paraffin-embedded liver biopsy samples were immunohistochemically analyzed using C4d polyclonal antibody, vascular cell adhesion ... ...

    Abstract Purpose: This study aimed to clarify the role of complement activation in fibrogenesis in BA.
    Methods: In total, 27 paraffin-embedded liver biopsy samples were immunohistochemically analyzed using C4d polyclonal antibody, vascular cell adhesion molecule-1 (VCAM-1), and CD45. The liver samples were obtained from 25 patients during Kasai operation, and two additional specimens were obtained from 2 patients by needle biopsy later at the time of liver function deterioration. The degree of liver fibrosis was histologically graded 1-3.
    Results: Among the 25 samples, 9 showed C4d-positive immunostaining localized on the endothelia of a few portal veins in the portal tract. The degree of fibrosis was correlated with C4d staining (p = 0.025). The age at Kasai operation correlated with the degree of fibrosis and the C4d positivity. Two needle biopsy samples were positive for C4d. Among 13 samples submitted for VCAM-1 staining, 2 negative samples were C4d negative and all positive C4d samples were VCAM-1 positive with CD45 mononuclear cell infiltration.
    Conclusion: These findings suggest that ongoing cirrhosis could be a result of progressive "vasculopathy" of the portal vein caused by humoral and cell-mediated immune interaction.
    MeSH term(s) Age Factors ; Biliary Atresia/complications ; Biliary Atresia/immunology ; Biliary Atresia/pathology ; Biopsy ; Complement C4b/immunology ; Endothelium/pathology ; Endothelium/ultrastructure ; Female ; Fluorescent Antibody Technique/methods ; Follow-Up Studies ; Humans ; Immunity, Humoral/immunology ; Infant ; Liver/immunology ; Liver/pathology ; Liver Cirrhosis/complications ; Liver Cirrhosis/immunology ; Liver Cirrhosis/pathology ; Male ; Observer Variation ; Peptide Fragments/immunology ; Portal Vein/immunology ; Portal Vein/pathology ; Portal Vein/ultrastructure ; Severity of Illness Index
    Chemical Substances Peptide Fragments ; Complement C4b (80295-50-7) ; complement C4d (80295-52-9)
    Language English
    Publishing date 2014-07-27
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 632773-4
    ISSN 1437-9813 ; 0179-0358
    ISSN (online) 1437-9813
    ISSN 0179-0358
    DOI 10.1007/s00383-014-3553-3
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  3. Article ; Online: Minimally invasive repair of hypospadiac urethral duplication.

    Yanai, Toshihiro / Kawakami, Hajime / Nango, Yoko / Watayo, Hiroko / Masuko, Takayuki / Hirai, Misako / Muraji, Toshihiro

    Pediatric surgery international

    2010  Volume 27, Issue 1, Page(s) 115–118

    Abstract: Urethral duplication is a rare congenital anomaly with various clinical presentations, and multiple techniques have been described for its repair. We report a 1-year-old boy with hypospadiac urethral duplication who presented with double urinary stream. ... ...

    Abstract Urethral duplication is a rare congenital anomaly with various clinical presentations, and multiple techniques have been described for its repair. We report a 1-year-old boy with hypospadiac urethral duplication who presented with double urinary stream. Voiding cystourethrography, retrograde urethrography, and cystourethroscopy showed the normal-caliber ventral urethra was dominant and the distal dorsal (non-dominant) urethra had a good caliber. Urethral reconstruction was performed with an incision of the adjoining walls of the both urethra in a side-to-side urethrourethrostomy fashion.
    MeSH term(s) Humans ; Hypospadias/surgery ; Infant ; Male ; Minimally Invasive Surgical Procedures/methods ; Treatment Outcome ; Urethra/abnormalities ; Urethra/surgery ; Urethral Diseases/surgery ; Urologic Surgical Procedures, Male/methods
    Language English
    Publishing date 2010-11-27
    Publishing country Germany
    Document type Case Reports ; Journal Article
    ZDB-ID 632773-4
    ISSN 1437-9813 ; 0179-0358
    ISSN (online) 1437-9813
    ISSN 0179-0358
    DOI 10.1007/s00383-010-2720-4
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  4. Article ; Online: Long-term survival with cloacal dysgenesis sequence.

    Yanai, Toshihiro / Urita, Yasuhisa / Amagai, Teruyoshi / Kawakami, Hajime / Watayo, Hiroko / Masuko, Takayuki / Matsuda, Satoshi / Hirai, Misako / Muraji, Toshihiro / Hamada, Hiromi

    Pediatric surgery international

    2011  Volume 28, Issue 1, Page(s) 107–110

    Abstract: Cloacal dysgenesis sequence (CDS) is a rare and lethal malformation. We report such a case of long-term survival, currently to 12 years of age. In the fetal period, she received a timely placement of vesico-amniotic shunt for a megabladder due to a ... ...

    Abstract Cloacal dysgenesis sequence (CDS) is a rare and lethal malformation. We report such a case of long-term survival, currently to 12 years of age. In the fetal period, she received a timely placement of vesico-amniotic shunt for a megabladder due to a severe urethral obstruction. Postnatally, cystostomy and colostomy were created because of no perineal opening of urethra, vagina, and anus. Anorectoplasty, construction of efferent conduit, and colostomy closure were performed at 4 years of age. Ileovaginoplasty and ileovesicostomy which was a Mitrofanoff-type of conduit, and labioplasty were performed at the age of 11 years. To the best of our knowledge, only five survivors with CDS over 1 year of age have been reported.
    MeSH term(s) Abnormalities, Multiple ; Adult ; Anal Canal/abnormalities ; Anal Canal/surgery ; Cloaca/abnormalities ; Cloaca/embryology ; Cloaca/surgery ; Colostomy/methods ; Diagnosis, Differential ; Female ; Follow-Up Studies ; Humans ; Infant, Newborn ; Pregnancy ; Pregnancy Outcome ; Reconstructive Surgical Procedures/methods ; Time Factors ; Ultrasonography, Prenatal ; Urethra/abnormalities ; Urethra/surgery ; Vagina/abnormalities ; Vagina/surgery
    Language English
    Publishing date 2011-12-14
    Publishing country Germany
    Document type Case Reports ; Journal Article
    ZDB-ID 632773-4
    ISSN 1437-9813 ; 0179-0358
    ISSN (online) 1437-9813
    ISSN 0179-0358
    DOI 10.1007/s00383-011-3020-3
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  5. Article ; Online: Implications of MYCN amplification in patients with stage 4 neuroblastoma who undergo intensive chemotherapy.

    Suita, Sachiyo / Tajiri, Tatsuro / Kaneko, Michio / Hirai, Misako / Mugishima, Hideo / Sugimoto, Toru / Tsuchida, Yoshiaki

    Journal of pediatric surgery

    2007  Volume 42, Issue 3, Page(s) 489–493

    Abstract: Background/purpose: This study aims to clarify the implications of MYCN amplification in patients with high-risk neuroblastomas treated with 2 different regimens of induction chemotherapy established by the Japan Study Group for Advanced Neuroblastoma.!# ...

    Abstract Background/purpose: This study aims to clarify the implications of MYCN amplification in patients with high-risk neuroblastomas treated with 2 different regimens of induction chemotherapy established by the Japan Study Group for Advanced Neuroblastoma.
    Methods: Between 1985 and 2003 in Japan, 392 patients with stage 4 neuroblastomas who were older than 12 months were treated with 2 regimens of induction chemotherapy (the combination of cyclophosphamide [CTX], cisplatin [CDDP], pirarubicin, and vincristine or etoposide). Regimen 91A3 or 98A3 (A3) (CTX 2400 mg/m2, CDDP 125 mg/m2) was a higher dose combination of CTX and CDDP than regimen 85A1 or 91A1 (A1) (CTX 1200 mg/m2, CDDP 90 mg/m2). The 392 cases were classified into 3 groups (A, 1 copy; B, 2-9 copies; C, more than 10 copies) based on the MYCN amplification status by a Southern blot analysis.
    Results: The 5-year overall survival rate (5-YS) was 41.1% for all 392 cases. Regarding the MYCN amplification status, the 5-YS was 46.6% for A group (n = 227), 22.7% for B group (n = 26), and 36.0% for C group (n = 139). A fluorescence in situ hybridization analysis showed the presence of the cells with more than 10 copies in cases with 2 to 9 copies based on the Southern blot findings. Of the 227 patients in a group, the 5-YS was 46.7% for the 70 cases treated by A3 and 47.0% for 154 cases treated by A1 (nonsignificant). The 5-YS of the 210 patients with stem cell transplantation (SCT) (51.%) was significantly better than that of the 127 patients without SCT (41.1%) (P < .05).
    Conclusions: Regarding the MYCN amplification status, the tumor aggressiveness might thus be different between 2 and 9 copies and a single copy of MYCN. In neuroblastomas with 2 and 9 copies of MYCN based on a Southern blot analysis, the MYCN amplification status should be analyzed using the fluorescence in situ hybridization method. Induction chemotherapy followed by SCT according to the Japan Study Group for Advanced Neuroblastoma protocol improved the outcome of neuroblastomas with MYCN amplification; however, obtaining a further improvement in the long-term survival of stage 4 neuroblastomas may therefore require the development of an even more effective treatment modality.
    MeSH term(s) Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Gene Amplification ; Humans ; N-Myc Proto-Oncogene Protein ; Neoadjuvant Therapy ; Neuroblastoma/drug therapy ; Neuroblastoma/genetics ; Neuroblastoma/therapy ; Nuclear Proteins/genetics ; Oncogene Proteins/genetics ; Stem Cell Transplantation ; Survival Analysis
    Chemical Substances MYCN protein, human ; N-Myc Proto-Oncogene Protein ; Nuclear Proteins ; Oncogene Proteins
    Language English
    Publishing date 2007-03
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 80165-3
    ISSN 1531-5037 ; 0022-3468
    ISSN (online) 1531-5037
    ISSN 0022-3468
    DOI 10.1016/j.jpedsurg.2006.10.056
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  6. Article ; Online: Placental vascular compromise in jejunoileal atresia.

    Komuro, Hiroaki / Amagai, Teruyoshi / Hori, Tetsuo / Hirai, Misako / Matoba, Kimio / Watanabe, Miho / Kaneko, Michio

    Journal of pediatric surgery

    2004  Volume 39, Issue 11, Page(s) 1701–1705

    Abstract: Background/purpose: The mechanisms of intrauterine vascular disruptions that result in the development of jejunoileal atresia (JIA) are not fully understood. Monochorionic twinning with fetal death of a cotwin is known to be correlated with the ... ...

    Abstract Background/purpose: The mechanisms of intrauterine vascular disruptions that result in the development of jejunoileal atresia (JIA) are not fully understood. Monochorionic twinning with fetal death of a cotwin is known to be correlated with the development of JIA in the survivor through placental communication. The aim of this study was to evaluate whether other placental vascular compromises might contribute to the development of JIA.
    Methods: Forty-five newborns (23 boys and 22 girls) who were treated for JIA at Tsukuba University Hospital from 1978 to 2003 were reviewed. Placental findings were informative in 23 cases.
    Results: No or slight abnormality of the placenta was found in 19 cases. Significant placental abnormalities were found in 4 patients who also had a low birth weight. One patient with apple peel atresia (APA) had excessive torsion of the umbilical cord (UC), which was inserted at the margin of the placenta, and there was an adjacent area of infarction. One patent with multiple atresia (MA) was a surviving monochorionic twin with intrauterine fetal death of the other. Another case of MA showed marginal insertion of the UC. Severe placental abnormalities including wide infarction, cyst formation, and marginal insertion of the UC were found in 1 case of MA. These 3 cases of MA were complicated with other anomalies including brain anomaly.
    Conclusions: Placental vascular compromises were involved infrequently in JIA but might possibly be responsible for the development of JIA as well as associated anomalies and a low birth weight as chronic insults since an early stage of gestation in some cases.
    MeSH term(s) Female ; Humans ; Ileum/abnormalities ; Infant, Newborn ; Intestinal Atresia/etiology ; Intestinal Atresia/pathology ; Jejunum/abnormalities ; Male ; Placenta/blood supply ; Placenta Diseases ; Pregnancy
    Language English
    Publishing date 2004-06-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80165-3
    ISSN 1531-5037 ; 0022-3468
    ISSN (online) 1531-5037
    ISSN 0022-3468
    DOI 10.1016/j.jpedsurg.2004.07.016
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  7. Article ; Online: Intrahepatic biliary cysts in children with biliary atresia who have had a Kasai operation.

    Watanabe, Miho / Hori, Tetsuo / Kaneko, Michio / Komuro, Hiroaki / Hirai, Misako / Inoue, Seiichiro / Urita, Yasuhisa / Hoshino, Noriko

    Journal of pediatric surgery

    2007  Volume 42, Issue 7, Page(s) 1185–1189

    Abstract: Purpose: In patients with biliary atresia who had undergone a Kasai operation, treatment of intrahepatic biliary cysts (IBCs), particularly when complicated by cholangitis, is often difficult because the clinical implications and the course of IBCs are ... ...

    Abstract Purpose: In patients with biliary atresia who had undergone a Kasai operation, treatment of intrahepatic biliary cysts (IBCs), particularly when complicated by cholangitis, is often difficult because the clinical implications and the course of IBCs are unclear. Thus, to determine the best treatment guideline, the morphology of IBCs, the clinical course, and the outcomes of such patients were evaluated.
    Patients and methods: A total of 44 patients with type III biliary atresia who underwent a Kasai operation from 1977 to 2005 were postoperatively examined for IBC by using ultrasonography and computed tomography. We classified the IBCs based on their number and shape.
    Results: Intrahepatic biliary cysts developed in 12 of 54 patients. Three patients with solitary simple cysts and 1 patient with multiple simple cysts had no history of cholangitis. Two patients with multiple simple cysts had cholangitis at the time of IBC diagnosis and were treated with percutaneous transhepatic cholangiodrainage (PTCD). Patients with simple IBCs did not develop persistent cholangitis and their prognosis depended largely on their liver function; 3 of 6 patients remained healthy without cholangitis, whereas 3 patients required liver transplantation (LT) because of progressive liver failure or worsening hepatopulmonary syndrome, and not severe cholangitis. On the other hand, all 6 patients with multiple complicated IBCs had persistent cholangitis, eventually requiring LT. Even after bile flow to the intestine was reestablished after PTCD, both IBCs and cholangitis recurred. These patients required LT because of severe cholangitis.
    Conclusions: Intrahepatic biliary cysts without cholangitis are not a source of infection and require no treatment. Simple IBCs with cholangitis can be controlled by antibiotics and/or PTCD. Patients with multiple complicated IBCs have a poor prognosis, requiring LT to control cholangitis. Although PTCD can control cholangitis in these patients as they wait for LT, PTCD does not alleviate it--LT is the final solution.
    MeSH term(s) Adolescent ; Adult ; Bile Duct Diseases/diagnostic imaging ; Bile Duct Diseases/etiology ; Bile Duct Diseases/therapy ; Bile Ducts, Intrahepatic ; Biliary Atresia/complications ; Biliary Atresia/surgery ; Child ; Child, Preschool ; Cysts/diagnostic imaging ; Cysts/etiology ; Cysts/therapy ; Drainage ; Female ; Humans ; Infant ; Male ; Prognosis ; Retrospective Studies ; Tomography, X-Ray Computed ; Treatment Outcome ; Ultrasonography
    Language English
    Publishing date 2007-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80165-3
    ISSN 1531-5037 ; 0022-3468
    ISSN (online) 1531-5037
    ISSN 0022-3468
    DOI 10.1016/j.jpedsurg.2007.02.035
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  8. Article: Rare association of severe hypoplasia of the abdominal aorta with imperforate anus, colonic atresia, and choledochal cyst.

    Komuro, Hiroaki / Takahashi, Miho I / Matoba, Kimio / Hori, Tetsuo / Hirai, Misako / Gotoh, Chikashi / Kaneko, Michio

    Pediatric surgery international

    2006  Volume 22, Issue 3, Page(s) 289–292

    Abstract: Hypoplasia of the abdominal aorta (HAA) is a rare condition that causes marked hypertension. Although multiple etiologies have been postulated for HAA, congenital structural anomalies are rarely observed except in cases associated with some hereditary ... ...

    Abstract Hypoplasia of the abdominal aorta (HAA) is a rare condition that causes marked hypertension. Although multiple etiologies have been postulated for HAA, congenital structural anomalies are rarely observed except in cases associated with some hereditary syndromes. The authors describe a neonatal case with HAA complicated by multiple anomalies including colonic atresia (CA), imperforate anus, choledochal cyst, facial cleft, and brain defects. This patient showed CA in the descending colon and caliber change in the transverse colon mimicking Hirschsprung disease, both of which were thought to be caused by vascular insult to the mesentery due to HAA. Although multiple surgical corrections were successfully performed, the hypertension was uncontrollable.
    MeSH term(s) Abnormalities, Multiple ; Anus, Imperforate/diagnosis ; Anus, Imperforate/surgery ; Aorta, Abdominal/abnormalities ; Aorta, Abdominal/surgery ; Aortic Diseases/congenital ; Aortic Diseases/diagnosis ; Aortic Diseases/surgery ; Choledochal Cyst/diagnosis ; Choledochal Cyst/surgery ; Colon, Descending/abnormalities ; Colon, Descending/surgery ; Colonic Diseases/congenital ; Colonic Diseases/diagnosis ; Colonic Diseases/surgery ; Diagnosis, Differential ; Digestive System Surgical Procedures/methods ; Humans ; Infant, Newborn ; Male ; Vascular Surgical Procedures/methods
    Language English
    Publishing date 2006-03
    Publishing country Germany
    Document type Case Reports ; Journal Article
    ZDB-ID 632773-4
    ISSN 0179-0358
    ISSN 0179-0358
    DOI 10.1007/s00383-005-1604-5
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  9. Article ; Online: Perforation of the colon in neonates.

    Komuro, Hiroaki / Urita, Yasuhisa / Hori, Tetsuo / Hirai, Misako / Kudou, Sumi / Gotoh, Chikashi / Kawakami, Hajime / Kaneko, Michio

    Journal of pediatric surgery

    2005  Volume 40, Issue 12, Page(s) 1916–1919

    Abstract: Purpose: Gastrointestinal perforation is a catastrophic condition in neonates, especially in premature neonates. Although perforation is commonly observed in the small intestine during the neonatal period, perforation of the colon is a rare condition. ... ...

    Abstract Purpose: Gastrointestinal perforation is a catastrophic condition in neonates, especially in premature neonates. Although perforation is commonly observed in the small intestine during the neonatal period, perforation of the colon is a rare condition. This study analyzed the clinical findings and results of perforation of the colon in neonates.
    Methods: Between 1989 and 2004, 8 neonates were treated for spontaneous perforation of the colon at our institute. These patients were retrospectively reviewed.
    Results: Gestational ages ranged from 36 to 41 weeks. Seven patients weighed above 2500 g, whereas one patient weighed 1800 g at birth. Perforations developed within 7 days after birth in 6 patients and before birth in two. Associated bowel diseases included rectosigmoid type of Hirschsprung's disease in two patients, immature ganglia in one, imperforate anus in one, colonic atresia in one, and necrotizing enterocolitis in one. An obvious cause was not identified in the remaining two. Six patients without definite anatomic obstructions, such as imperforate anus or colonic atresia, required evaluations for suspected Hirschsprung's disease. All 8 patients underwent colostomy and recovered from peritonitis. Seven survived, but one died of sudden infant death syndrome.
    Conclusions: In this study, perforation of the colon during the neonatal period mostly occurred in term or near-term neonates and carried a good prognosis. During management, it was important to identify Hirschsprung's and its allied disorders as a cause of perforation.
    MeSH term(s) Colonic Diseases/complications ; Colonic Diseases/pathology ; Colonic Diseases/surgery ; Colostomy ; Fatal Outcome ; Female ; Humans ; Infant, Newborn ; Intestinal Obstruction/complications ; Intestinal Perforation/complications ; Intestinal Perforation/pathology ; Intestinal Perforation/surgery ; Male ; Peritonitis/etiology ; Prognosis ; Retrospective Studies ; Sudden Infant Death ; Treatment Outcome
    Language English
    Publishing date 2005-12
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 80165-3
    ISSN 1531-5037 ; 0022-3468
    ISSN (online) 1531-5037
    ISSN 0022-3468
    DOI 10.1016/j.jpedsurg.2005.08.006
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  10. Article ; Online: The etiologic role of intrauterine volvulus and intussusception in jejunoileal atresia.

    Komuro, Hiroaki / Hori, Tetsuo / Amagai, Teruyoshi / Hirai, Misako / Yotsumoto, Katsumi / Urita, Yasuhisa / Gotoh, Chikashi / Kaneko, Michio

    Journal of pediatric surgery

    2004  Volume 39, Issue 12, Page(s) 1812–1814

    Abstract: Purpose: Although intussusception has been reported as quite a rare cause of jejunoileal atresia (JIA), pediatric surgeons have noted the frequent presence of intussusception as well as volvulus at surgery. The aim of this study was to investigate the ... ...

    Abstract Purpose: Although intussusception has been reported as quite a rare cause of jejunoileal atresia (JIA), pediatric surgeons have noted the frequent presence of intussusception as well as volvulus at surgery. The aim of this study was to investigate the contribution of intrauterine intussusception and volvulus to the development of JIA.
    Methods: In 48 newborns (24 boys and 24 girls) treated for JIA at our hospital between 1978 and 2004, the operative and pathologic findings were reviewed.
    Results: Intussusception was responsible for gap and cord type atresia in 12 cases (25%). The cord showed an atrophic intestinal lumen in 2 cases. Volvulus was observed in 13 cases. Volvulus and intussusception were simultaneously noted in 1 case. This suggested that intussusception was the cause of the atresia, whereas volvulus was a secondary event. Neither intussusception nor volvulus was observed in high jejunal, apple peel, or multiple atresia.
    Conclusions: Intrauterine volvulus and intussusception were commonly observed in single mid- and low JIA. Thus, intrauterine intussusception may be a common cause of gap and cord type JIA. Volvulus may not only cause JIA but also result from anatomic changes after the development of JIA in some cases.
    MeSH term(s) Female ; Fetal Diseases ; Humans ; Ileal Diseases/complications ; Ileum/abnormalities ; Infant, Newborn ; Intestinal Atresia/etiology ; Intestinal Volvulus/complications ; Intussusception/complications ; Jejunal Diseases/complications ; Jejunum/abnormalities ; Male
    Language English
    Publishing date 2004-06-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80165-3
    ISSN 1531-5037 ; 0022-3468
    ISSN (online) 1531-5037
    ISSN 0022-3468
    DOI 10.1016/j.jpedsurg.2004.08.037
    Database MEDical Literature Analysis and Retrieval System OnLINE

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