LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 1998

Search options

  1. Article ; Online: Clinical Results and Prognostic Factors in BNCT for Recurrent Squamous Cell Carcinoma of the Head and Neck under the Japan National Health Insurance System: A Retrospective Study of the Initial 47 Patients.

    Hirose, Katsumi / Sato, Mariko

    International journal of radiation oncology, biology, physics

    2024  

    Abstract: Purpose: Recurrent head and neck cancer presents a therapeutic challenge due to cumulative toxicity from initial radiation therapy, limiting re-irradiation options. Boron neutron capture therapy (BNCT) offers a promising alternative, selectively ... ...

    Abstract Purpose: Recurrent head and neck cancer presents a therapeutic challenge due to cumulative toxicity from initial radiation therapy, limiting re-irradiation options. Boron neutron capture therapy (BNCT) offers a promising alternative, selectively delivering a radical dose to tumors while sparing adjacent normal tissue. This study investigates the initial clinical outcomes and prognostic factors associated with BNCT for recurrent squamous cell carcinoma of the head and neck.
    Materials and methods: This retrospective analysis investigated the initial 47 patients treated with BNCT between May 2020 and February 2021 in Japan. All patients had received radiotherapy with a median dose of 70 Gy (range, 44-176) prior to BNCT. Median tumor size was 11 cm
    Results: Efficacy analysis revealed a 51% complete response rate and a 74% overall response rate. Disease-free survival rates at 1 and 2 years were 34.6% and 26.6%, respectively. Overall survival rates at 1 and 2 years were 86.1% and 66.5%, respectively. Multivariate analysis revealed that, among the patient characteristics, whether the lesion was mucosal had a significant impact on achieving complete response.
    Conclusions: This study provided valuable insights into the early integration of BNCT into routine clinical practice, highlighting its efficacy and safety. Technical improvements are needed to ensure precise dose administration. Ongoing prospective studies, such as the phase II REBIVAL study, will further elucidate the role of BNCT in recurrent head and neck cancer.
    Language English
    Publishing date 2024-04-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 197614-x
    ISSN 1879-355X ; 0360-3016
    ISSN (online) 1879-355X
    ISSN 0360-3016
    DOI 10.1016/j.ijrobp.2024.03.041
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1218: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article ; Online: Atmospheric effects of Fukushima nuclear accident: A review from a sight of atmospheric monitoring.

    Hirose, Katsumi

    Journal of environmental radioactivity

    2020  Volume 218, Page(s) 106240

    Abstract: The Fukushima Daiichi Nuclear Power Plant (FDNPP) accident, which occurred in March 2011, has released large amounts of radionuclides (such as radioiodine and radiocesium) into the atmosphere, resulting in the contamination of terrestrial and marine ... ...

    Abstract The Fukushima Daiichi Nuclear Power Plant (FDNPP) accident, which occurred in March 2011, has released large amounts of radionuclides (such as radioiodine and radiocesium) into the atmosphere, resulting in the contamination of terrestrial and marine environments. To assess radiological and environmental effects of the FDNPP-derived radionuclides, huge amounts of radioactive monitoring activities have been conducted to environmental samples. In this paper, we review results of atmospheric radioactivity monitoring for the FDNPP accident. Learning from atmospheric radioactivity monitoring of the FDNPP accident is as follows; 1. At the initial stage of accident, large spatiotemporal variability of emitted radionuclides near the FDNPP site occurred at short (less than 1 h) time scale and small (less than 10 km) space scale due to complicated emissions of radionuclides and variable flow of Fukushima radioactive plume, 2. Chemical form of FDNPP-derived radionuclides, in which a typical example is coexistence of
    MeSH term(s) Atmosphere ; Cesium Radioisotopes ; Fukushima Nuclear Accident ; Iodine Radioisotopes ; Japan ; Nuclear Power Plants ; Radiation Monitoring ; Water Pollutants, Radioactive
    Chemical Substances Cesium Radioisotopes ; Iodine Radioisotopes ; Water Pollutants, Radioactive
    Language English
    Publishing date 2020-03-18
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1483112-0
    ISSN 1879-1700 ; 0265-931X
    ISSN (online) 1879-1700
    ISSN 0265-931X
    DOI 10.1016/j.jenvrad.2020.106240
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article ; Online: Temporal changes of

    Hirose, Katsumi / Povinec, Pavel P

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 22963

    Abstract: Deep-ocean sediments, similarly to seawater, are important reservoirs ... ...

    Abstract Deep-ocean sediments, similarly to seawater, are important reservoirs of
    Language English
    Publishing date 2023-12-27
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-49083-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article: Pilsicainide Toxicity-Induced Brugada-Like ST Segment Elevation and Increased Pacing Voltage Threshold.

    Hirose, Kosuke / Arita, Yoh / Ogasawara, Nobuyuki

    Cureus

    2024  Volume 16, Issue 1, Page(s) e51576

    Abstract: Pilsicainide is a class Ic antiarrhythmic agent that exhibits fully selective sodium channel blockade. In Japan, it is one of the most prescribed medicines for rhythm control in atrial fibrillation. Pilsicainide is mainly excreted by the kidney. ... ...

    Abstract Pilsicainide is a class Ic antiarrhythmic agent that exhibits fully selective sodium channel blockade. In Japan, it is one of the most prescribed medicines for rhythm control in atrial fibrillation. Pilsicainide is mainly excreted by the kidney. Therefore, the plasma concentration of pilsicainide is likely to be increased in patients with renal insufficiency. In this case report, a 90-year-old woman presented with generalized fatigue and loss of appetite. Her ECG showed marked bradycardia and coved-type ST-segment elevation similar to that of the Brugada type 1 pattern. Owing to dehydration, her renal function indices worsened compared with those measured four months prior. The plasma pilsicainide concentration was elevated to 2.67 µg/mL (therapeutic range: 0.20-0.90 µg/mL), indicating pilsicainide toxicity. A transvenous temporary pacemaker was placed; however, the pacing voltage threshold was increased at several sites within the right ventricle. Pilsicainide administration was immediately discontinued. On day 2 of admission, ventricular backup pacing was no longer required, and there was an improvement in renal function and heart failure symptoms, such as pulmonary edema and cardiomegaly. The ECG changes improved alongside the renal function and as the plasma concentration of pilsicainide decreased. In conclusion, elevated plasma concentrations of pilsicainide can induce life-threatening arrhythmias and pacing failure. Therefore, clinicians should prescribe pilsicainide cautiously, particularly in older patients.
    Language English
    Publishing date 2024-01-03
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.51576
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article: A Case of Odontoid Osteomyelitis.

    Hashimoto, Etaro / Miyazaki, Kenji / Hirose, Kazuhito / Maeno, Tetsuhiro

    Cureus

    2024  Volume 16, Issue 1, Page(s) e52012

    Abstract: Odontoid osteomyelitis is a rare infectious disease that manifests as fever and posterior neck pain, while crowned dens syndrome is a relatively common inflammatory disorder with similar signs and symptoms. We describe the case of a 90-year-old woman ... ...

    Abstract Odontoid osteomyelitis is a rare infectious disease that manifests as fever and posterior neck pain, while crowned dens syndrome is a relatively common inflammatory disorder with similar signs and symptoms. We describe the case of a 90-year-old woman presenting with fever, posterior neck pain, throat pain, and headache. Crowned dens syndrome was initially diagnosed based on the clinical picture and calcification around the odontoid process on cervical spine CT. However, the diagnosis was revised to odontoid osteomyelitis following the detection of
    Language English
    Publishing date 2024-01-10
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.52012
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article ; Online: Identification and characterization of novel N-acylhomoserine lactonase from nonpathogenic Allorhizobium vitis, a candidate for biocontrol agent.

    Morohoshi, Tomohiro / Hirose, Koki / Someya, Nobutaka

    Journal of bioscience and bioengineering

    2024  

    Abstract: Some strains of nonpathogenic Allorhizobium vitis can control crown gall disease in grapevines caused by pathogenic A. vitis and are considered candidates for biocontrol agents. Many plant pathogenic bacteria regulate the expression of their virulence ... ...

    Abstract Some strains of nonpathogenic Allorhizobium vitis can control crown gall disease in grapevines caused by pathogenic A. vitis and are considered candidates for biocontrol agents. Many plant pathogenic bacteria regulate the expression of their virulence genes via quorum sensing using N-acylhomoserine lactone (AHL) as a signaling compound. The eight nonpathogenic A. vitis strains used in this study showed AHL-degrading activity. The complete genome sequence of A. vitis MAFF 212306 contained three AHL lactonase gene homologs. When these genes were cloned and transformed into Escherichia coli DH5α, E. coli harboring the aiiV gene (RvVAR031_27660) showed AHL-degrading activity. The aiiV coding region was successfully amplified by polymerase chain reaction from the genomes of all eight strains of nonpathogenic A. vitis. Purified His-tagged AiiV exhibited AHL lactonase activity by hydrolyzing the lactone ring of AHL. AiiV had an optimal temperature of approximately 30 °C; however, its thermostability decreased above 40 °C. When the AiiV-expressing plasmid was transformed into Pectobacterium carotovorum subsp. carotovorum NBRC 3830, AHL production by NBRC 3830 decreased below the detection limit, and its maceration activity, which was controlled by quorum sensing, almost disappeared. These results suggest the potential use of AHL-degrading nonpathogenic A. vitis for the inhibition of crown gall disease in grapevines and other plant diseases controlled by quorum sensing.
    Language English
    Publishing date 2024-04-03
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 1465387-4
    ISSN 1347-4421 ; 1389-1723
    ISSN (online) 1347-4421
    ISSN 1389-1723
    DOI 10.1016/j.jbiosc.2024.03.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Bonn / Germany

    Z 4728: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  7. Article ; Online: RIM-BP2 regulates Ca

    Miyano, Rinako / Sakamoto, Hirokazu / Hirose, Kenzo / Sakaba, Takeshi

    eLife

    2024  Volume 12

    Abstract: Synaptic vesicles dock and fuse at the presynaptic active zone (AZ), the specialized site for transmitter release. AZ proteins play multiple roles such as recruitment of ... ...

    Abstract Synaptic vesicles dock and fuse at the presynaptic active zone (AZ), the specialized site for transmitter release. AZ proteins play multiple roles such as recruitment of Ca
    MeSH term(s) Animals ; Mice ; Biological Transport ; Mice, Knockout ; Mossy Fibers, Hippocampal ; Neurotransmitter Agents ; Synapses ; Synaptic Transmission ; Intracellular Signaling Peptides and Proteins/genetics ; Calcium Channels/metabolism
    Chemical Substances Neurotransmitter Agents ; Rimbp2 protein, mouse ; Intracellular Signaling Peptides and Proteins ; Calcium Channels
    Language English
    Publishing date 2024-02-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 2687154-3
    ISSN 2050-084X ; 2050-084X
    ISSN (online) 2050-084X
    ISSN 2050-084X
    DOI 10.7554/eLife.90799
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Article ; Online: Spontaneous Coronary Artery Dissection With Concomitant Coronary Vasospasm.

    Hirose, Kazutoshi / Kamei, Izaya / Tanabe, Takahiro / Haraki, Tatsuo

    JACC. Case reports

    2024  Volume 29, Issue 7, Page(s) 102281

    Abstract: We herein describe a case of acute myocardial infarction due to spontaneous coronary artery dissection complicated by vasospastic angina. Given the need for different clinical management strategies of these cardiac manifestations, clinicians should ... ...

    Abstract We herein describe a case of acute myocardial infarction due to spontaneous coronary artery dissection complicated by vasospastic angina. Given the need for different clinical management strategies of these cardiac manifestations, clinicians should consider the possibility of concomitant vasospasm in cases of spontaneous coronary artery dissection.
    Language English
    Publishing date 2024-02-28
    Publishing country Netherlands
    Document type Case Reports
    ISSN 2666-0849
    ISSN (online) 2666-0849
    DOI 10.1016/j.jaccas.2024.102281
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  9. Article ; Online: An exploration of elite Japanese female footballers' acute cultural transition experiences in Europe.

    Hirose, Kotone / Meijen, Carla

    Science & medicine in football

    2022  Volume 6, Issue 5, Page(s) 660–667

    Abstract: The globalisation of women's football reflects the increasing number of female football players moving abroad for their professional careers. Yet, the cultural transition of Asian female athletes into western culture is merely studied. This study focused ...

    Abstract The globalisation of women's football reflects the increasing number of female football players moving abroad for their professional careers. Yet, the cultural transition of Asian female athletes into western culture is merely studied. This study focused on the experiences of nine elite Japanese female football players competing in the professional league in Spain and Portugal in the immediate period after moving from Japan. During the semi-structured interview participants shared their experiences of their sporting and non-sporting lives abroad and the impact of this transition on their athletic and non-athletic self and well-being. By using thematic analysis three themes illustrating their positive acculturation experiences were identified: opening up to people's kindness, redefining family, and learning a new mentality. Based on the concept of two types of happiness (interdependent and independent), and the collectivism versus individualism dichotomy, the influence of culture on the relationship between life satisfaction and athletic performance, personal growth, and expanding the support system were critically discussed. Practical implications include insights for sport professionals on how cultural change can affect transnational athletes' sporting and non-sporting lives and influence their mental health.
    MeSH term(s) Female ; Humans ; Athletes/psychology ; East Asian People ; Europe ; Soccer/psychology
    Language English
    Publishing date 2022-10-02
    Publishing country England
    Document type Journal Article
    ISSN 2473-4446
    ISSN (online) 2473-4446
    DOI 10.1080/24733938.2022.2133161
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  10. Article ; Online: Ten years of investigations of Fukushima radionuclides in the environment: A review on process studies in environmental compartments.

    Hirose, Katsumi / Povinec, Pavel P

    Journal of environmental radioactivity

    2022  Volume 251-252, Page(s) 106929

    Abstract: In March 2011, severe nuclear accident happened at the Fukushima Dai-ichi Nuclear Power Plant (FDNPP) after the gigantic earthquake and following huge tsunami wave. A lot of investigations to assess environmental and radiological impacts of released ... ...

    Abstract In March 2011, severe nuclear accident happened at the Fukushima Dai-ichi Nuclear Power Plant (FDNPP) after the gigantic earthquake and following huge tsunami wave. A lot of investigations to assess environmental and radiological impacts of released radionuclides have been conducted by domestic and international organizations. Environmental radioactivity research related to the FDNPP accident has spread widely over different scientific fields due to specific features of the accident, and specifically its impact on the marine environment. The present paper summarizes major lessons learned from the environmental investigations of the FDNPP accident. Environmental radioactivity studies have typical interdisciplinary character; especially physics and chemistry are fundamental as a base of process studies in the environment. In this sight, we review chemical aspects regarding FDNPP-derived radiocesium transfer within and between compartments (atmosphere, ocean and land). We also discuss future trends in investigations of behavior of anthropogenic radionuclides in the environment, important not only for a better understanding of impacts of the FDNPP accident on the environment, but also for improving our general knowledge of the total environment in the Anthropocene era and its protection for the future.
    MeSH term(s) Cesium Radioisotopes/analysis ; Fukushima Nuclear Accident ; Japan ; Nuclear Power Plants ; Radiation Monitoring ; Water Pollutants, Radioactive/analysis
    Chemical Substances Cesium Radioisotopes ; Water Pollutants, Radioactive
    Language English
    Publishing date 2022-06-16
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1483112-0
    ISSN 1879-1700 ; 0265-931X
    ISSN (online) 1879-1700
    ISSN 0265-931X
    DOI 10.1016/j.jenvrad.2022.106929
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top