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  1. Article ; Online: The role of older adult-focused social vulnerability on the relationship between temperature and emergency department attendance in a subtropical Asian city.

    Ho, Janice Ying-En / Lai, Eric Tc / Chau, Pui Hing / Chong, Ka Chun / Woo, Jean

    Archives of gerontology and geriatrics

    2023  Volume 117, Page(s) 105195

    Abstract: Purpose: Older adults exhibit a wide range of capabilities and vulnerabilities that affect their capacity to respond to heat. This study analysed the associations between hot temperatures and Accident & Emergency (A&E) attendance taking into account ... ...

    Abstract Purpose: Older adults exhibit a wide range of capabilities and vulnerabilities that affect their capacity to respond to heat. This study analysed the associations between hot temperatures and Accident & Emergency (A&E) attendance taking into account older adult-focused social vulnerability.
    Methods: Daily A&E attendance data of Young-old (65-74) and Old-old (75+) was obtained for Hong Kong 2010-2019 hot seasons and stratified into three Social Vulnerability Index (SVI) groups (Low, Moderate, High). Mean temperature (lag 0-2) was analysed on A&E attendance at each SVI using Generalized Additive Models and Distributed Lag Non-linear Models.
    Results: High temperatures were associated with increased same-day (lag 0) relative risk (RR) of A&E attendance for Young-old and Old-old in High SVI districts, with RR being 1.024 (95 % CI: 1.011, 1.037) and 1.036 (95 % CI: 1.018, 1.053), respectively. The Old-old living in Moderate and Low SVI districts also demonstrated increased RR of 1.037 (95 % CI: 1.028, 1.047) and 1.022 (95 % CI: 1.009, 1.036), respectively. Fewer emergency visits were found on the subsequent day (lag 1) of hot temperatures.
    Conclusions: Older adults, both young-old and old-old, living in districts with higher social vulnerability tended to have increased risk of A&E attendance associated with same-day high temperature. With climate change and rapidly aging population, cities should prepare to meet needs of more vulnerable older adults in extreme heat.
    MeSH term(s) Humans ; Aged ; Temperature ; Cities ; Social Vulnerability ; Hot Temperature ; Emergency Service, Hospital
    Language English
    Publishing date 2023-09-11
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 603162-6
    ISSN 1872-6976 ; 0167-4943
    ISSN (online) 1872-6976
    ISSN 0167-4943
    DOI 10.1016/j.archger.2023.105195
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Relationship between temperature variability and daily hospitalisations in Hong Kong over two decades.

    Li, Kehang / Wang, Yawen / Jiang, Xiaoting / Li, Conglu / Chen, Jinjian / Zeng, Yiqian / Zhao, Shi / Ho, Janice Ying-En / Ran, Jinjun / Han, Lefei / Wei, Yuchen / Yeoh, Eng Kiong / Chong, Ka Chun

    Journal of global health

    2023  Volume 13, Page(s) 4122

    Abstract: Background: Studies have highlighted the impacts of temperature variability (TV) on mortality from respiratory diseases and cardiovascular diseases, with inconsistent results specifically in subtropical urban areas than temperate ones. We aimed to fully ...

    Abstract Background: Studies have highlighted the impacts of temperature variability (TV) on mortality from respiratory diseases and cardiovascular diseases, with inconsistent results specifically in subtropical urban areas than temperate ones. We aimed to fully determine TV-associated health risks over a spectrum of diseases and various subgroups in a subtropical setting.
    Methods: Using inpatient data from all public hospitals in Hong Kong from 1999 to 2019, we examined the TV-hospitalisation associations by causes, ages, and seasons by fitting a quasi-Poisson regression. We presented the results as estimated percentage changes of hospitalisations per interquartile range (IQR) of TV.
    Results: TVs in exposure days from 0-5 days (TV
    Conclusions: Our population-based study highlighted that TV-related health burden, usually regarded as minimal compared to other environmental factors, should receive more attention and be addressed in future relevant health policies, especially for vulnerable populations during the cold seasons.
    MeSH term(s) Humans ; Aged ; Hong Kong/epidemiology ; Temperature ; Hospitalization ; Respiration Disorders ; Respiratory Tract Diseases/epidemiology ; Seasons ; Cardiovascular Diseases
    Language English
    Publishing date 2023-10-13
    Publishing country Scotland
    Document type Journal Article
    ZDB-ID 2741629-X
    ISSN 2047-2986 ; 2047-2986
    ISSN (online) 2047-2986
    ISSN 2047-2986
    DOI 10.7189/jogh.13.04122
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Association of nirmatrelvir-ritonavir with post-acute sequelae and mortality in patients admitted to hospital with COVID-19: a retrospective cohort study.

    Wang, Huwen / Wei, Yuchen / Hung, Chi Tim / Lin, Guozhang / Jiang, Xiaoting / Li, Conglu / Jia, Katherine Min / Yam, Carrie Ho Kwan / Chow, Tsz Yu / Ho, Janice Ying-En / Wang, Yawen / Zhao, Shi / Guo, Zihao / Li, Kehang / Yang, Aimin / Mok, Chris Ka Pun / Hui, David S C / Yeoh, Eng Kiong / Chong, Ka Chun

    The Lancet. Infectious diseases

    2024  

    Abstract: Background: Studies have established the short-term efficacy of nirmatrelvir-ritonavir in managing COVID-19, yet its effect on post-COVID-19 condition, especially in patients admitted to hospital, remains understudied. This study aimed to examine the ... ...

    Abstract Background: Studies have established the short-term efficacy of nirmatrelvir-ritonavir in managing COVID-19, yet its effect on post-COVID-19 condition, especially in patients admitted to hospital, remains understudied. This study aimed to examine the effect of nirmatrelvir-ritonavir on post-COVID-19 condition among patients admitted to hospital in Hong Kong.
    Methods: This retrospective cohort study used real-world, territory-wide inpatient records, vaccination records, and confirmed COVID-19 case data from the Hong Kong Hospital Authority and Department of Health, The Government of the Hong Kong Special Administrative Region. Patients aged 18 years and older who tested positive for SARS-CoV-2 between March 11, 2022, and Oct 10, 2023, and who were admitted to hospital with COVID-19 were included. The treatment group included patients prescribed nirmatrelvir-ritonavir within 5 days of symptom onset, excluding those prescribed molnupiravir within 21 days, and the control group had no exposure to either nirmatrelvir-ritonavir or molnupiravir. The outcomes were post-acute inpatient death and 13 sequelae (congestive heart failure, atrial fibrillation, coronary artery disease, deep vein thrombosis, chronic pulmonary disease, acute respiratory distress syndrome, interstitial lung disease, seizure, anxiety, post-traumatic stress disorder, end-stage renal disease, acute kidney injury, and pancreatitis). These outcomes were evaluated starting at 21 days after the positive RT-PCR date in each respective cohort constructed for the outcome. Standardised mortality ratio weights were applied to balance covariates, and Cox proportional hazards regression was used to investigate the relationship between nirmatrelvir-ritonavir and outcomes.
    Findings: 136 973 patients were screened for inclusion, among whom 50 055 were eligible and included in the analysis (24 873 [49·7%] were female and 25 182 [50·3%] were male). 15 242 patients were prescribed nirmatrelvir-ritonavir during acute COVID-19 and 23 756 patients were included in the control group; 11 057 patients did not meet our definition for the exposed and unexposed groups. Patients were followed up for a median of 393 days (IQR 317-489). In the nirmatrelvir-ritonavir group compared with the control group, there was a significantly lower hazard of post-acute inpatient death (hazard ratio 0·62 [95% CI 0·57-0·68]; p<0·0001), congestive heart failure (0·70 [0·58-0·85]; p=0·0002), atrial fibrillation (0·63 [0·52-0·76]; p<0·0001), coronary artery disease (0·71 [0·59-0·85]; p=0·0002), chronic pulmonary disease (0·68 [0·54-0·86]; p=0·0011), acute respiratory distress syndrome (0·71 [0·58-0·86]; p=0·0007), interstitial lung disease (0·17 [0·04-0·75]; p=0·020), and end-stage renal disease (0·37 [0·18-0·74]; p=0·0049). There was no evidence indicating difference between the groups in deep vein thrombosis, seizure, anxiety, post-traumatic stress disorder, acute kidney injury, and pancreatitis.
    Interpretation: This study showed extended benefits of nirmatrelvir-ritonavir for reducing the risk of post-acute inpatient death as well as cardiovascular and respiratory complications among patients admitted to hospital with COVID-19. Further research is essential to uncover the underlying mechanisms responsible for these observed negative associations and to devise effective strategies for preventing the onset of post-acute sequelae.
    Funding: Health and Medical Research Fund, Research Grants Council theme-based research schemes, and Research Grants Council Collaborative Research Fund.
    Language English
    Publishing date 2024-05-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2061641-7
    ISSN 1474-4457 ; 1473-3099
    ISSN (online) 1474-4457
    ISSN 1473-3099
    DOI 10.1016/S1473-3099(24)00217-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Is "Perceived Water Insecurity" Associated with Disaster Risk Perception, Preparedness Attitudes, and Coping Ability in Rural China? (A Health-EDRM Pilot Study).

    Ho, Janice Ying-En / Chan, Emily Ying Yang / Lam, Holly Ching Yu / Yeung, May Pui Shan / Wong, Carol Ka Po / Yung, Tony Ka Chun

    International journal of environmental research and public health

    2019  Volume 16, Issue 7

    Abstract: Water security is essential for maintaining health and well-being, and for reducing a population's vulnerability in a disaster. Among resource-poor villagers in China, water-related disasters and climate change may increasingly affect people's water ... ...

    Abstract Water security is essential for maintaining health and well-being, and for reducing a population's vulnerability in a disaster. Among resource-poor villagers in China, water-related disasters and climate change may increasingly affect people's water security. The purpose of this study was to explore the relationship between perceived water security and disaster risk perception in a rural ethnic minority community. A cross-sectional household survey was conducted in 2015 in Xingguang village, Chongqing, China, examining the association between villagers' perceptions of household water security, disaster risk, and sociodemographic variables. Among 52 household representatives, 84.6% relied on rainwater as their main water source and 63.5% reported having insufficient water on a regular basis. Only 32.7% perceived themselves to be living in a high-risk area, of which climate-related disasters such as storms (44.4%) and droughts (38.9%) were the most frequently reported disasters in their area. Insufficient water quantity, previous disaster experience, and household members on chronic disease medication were found to be associated with higher disaster risk perception. Perceived water security indicators were not found to be predictors of preparedness attitudes and coping ability. Addressing water sufficiency in both disaster risk reduction strategies and long-term water management will be necessary to improve the health and livelihood of rural villagers in the coming decades.
    MeSH term(s) Adaptation, Psychological ; Adolescent ; Adult ; Aged ; Attitude ; China ; Cross-Sectional Studies ; Disaster Planning/organization & administration ; Ethnic Groups ; Female ; Humans ; Male ; Middle Aged ; Minority Groups ; Perception ; Pilot Projects ; Risk ; Rural Population ; Vulnerable Populations ; Water Supply ; Young Adult
    Language English
    Publishing date 2019-04-08
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1660-4601
    ISSN (online) 1660-4601
    DOI 10.3390/ijerph16071254
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Narrative review of non-pharmaceutical behavioural measures for the prevention of COVID-19 (SARS-CoV-2) based on the Health-EDRM framework.

    Yang Chan, Emily Ying / Shahzada, Tayyab Salim / Sham, Tiffany Sze Tung / Dubois, Caroline / Huang, Zhe / Liu, Sida / Ho, Janice Ying-En / Hung, Kevin K C / Kwok, Kin On / Shaw, Rajib

    British medical bulletin

    2020  Volume 136, Issue 1, Page(s) 46–87

    Abstract: Introduction: Non-pharmaceutical measures to facilitate a response to the COVID-19 pandemic, a disease caused by novel coronavirus SARS-CoV-2, are urgently needed. Using the World Health Organization (WHO) health emergency and disaster risk management ( ... ...

    Abstract Introduction: Non-pharmaceutical measures to facilitate a response to the COVID-19 pandemic, a disease caused by novel coronavirus SARS-CoV-2, are urgently needed. Using the World Health Organization (WHO) health emergency and disaster risk management (health-EDRM) framework, behavioural measures for droplet-borne communicable diseases and their enabling and limiting factors at various implementation levels were evaluated.
    Sources of data: Keyword search was conducted in PubMed, Google Scholar, Embase, Medline, Science Direct, WHO and CDC online publication databases. Using the Oxford Centre for Evidence-Based Medicine review criteria, 10 bottom-up, non-pharmaceutical prevention measures from 104 English-language articles, which published between January 2000 and May 2020, were identified and examined.
    Areas of agreement: Evidence-guided behavioural measures against transmission of COVID-19 in global at-risk communities were identified, including regular handwashing, wearing face masks and avoiding crowds and gatherings.
    Areas of concern: Strong evidence-based systematic behavioural studies for COVID-19 prevention are lacking.
    Growing points: Very limited research publications are available for non-pharmaceutical measures to facilitate pandemic response.
    Areas timely for research: Research with strong implementation feasibility that targets resource-poor settings with low baseline health-EDRM capacity is urgently needed.
    MeSH term(s) Attitude to Health ; COVID-19/epidemiology ; COVID-19/prevention & control ; COVID-19/psychology ; Disease Transmission, Infectious/prevention & control ; Health Promotion/methods ; Humans ; Outcome Assessment, Health Care/methods ; Primary Prevention/methods ; Risk Reduction Behavior ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-10-09
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 213294-1
    ISSN 1471-8391 ; 0007-1420
    ISSN (online) 1471-8391
    ISSN 0007-1420
    DOI 10.1093/bmb/ldaa030
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Socio-demographic predictors of health and environmental co-benefit behaviours for climate change mitigation in urban China.

    Chan, Emily Ying Yang / Wang, Susan Shuxin / Ho, Janice Ying-En / Huang, Zhe / Liu, Sida / Guo, Chunlan

    PloS one

    2017  Volume 12, Issue 11, Page(s) e0188661

    Abstract: Objective: This study aims to examine the patterns and socio-demographic predictors of health and environmental co-benefit behaviours that support climate change mitigation in a densely populated Asian metropolis-Hong Kong.: Methods: A population- ... ...

    Abstract Objective: This study aims to examine the patterns and socio-demographic predictors of health and environmental co-benefit behaviours that support climate change mitigation in a densely populated Asian metropolis-Hong Kong.
    Methods: A population-based, stratified and cross-sectional random digit dialling telephone survey study was conducted between January and February 2016, among the Cantonese-speaking population aged 15 and above in Hong Kong. Socio-demographic data and the self-reported practice of 10 different co-benefit behaviours were solicited. Ethics approval and participant's verbal consent were sought.
    Findings: The study sample consisted of 1,017 respondents (response rate: 63.6%) were comparable to the age, gender and geographical distributions of the Hong Kong population found in the latest 2011 Hong Kong Population Census. Among the co-benefit behaviours, using less packaging and disposable shopping bags were practiced in the highest frequency (70.1%). However, four behaviours were found to have never been practiced by more than half of the respondents, including bringing personal eating utensils when dining in restaurants or small eateries, showering less than five minutes, having one vegetarian meal a week, and buying more organic food. Results of multivariable logistic regression showed that frequency of practicing co-benefit behaviours were consistently associated with gender and age.
    Conclusion: Urban residents in Hong Kong do not engage in the practice of co-benefit behaviours in a uniform way. In general, females and older people are more likely to adopt co-benefit behaviours in their daily lives. Further research to assess the knowledge and attitudes of the population towards these co-benefit behaviours will provide support to relevant climate change mitigation policies and education programmes.
    MeSH term(s) Adolescent ; Adult ; Aged ; China/epidemiology ; Cities ; Climate Change ; Demography ; Environment ; Female ; Health ; Health Knowledge, Attitudes, Practice ; Hong Kong/epidemiology ; Humans ; Logistic Models ; Male ; Middle Aged ; Multivariate Analysis ; Young Adult
    Language English
    Publishing date 2017
    Publishing country United States
    Document type Journal Article
    ISSN 1932-6203
    ISSN (online) 1932-6203
    DOI 10.1371/journal.pone.0188661
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Narrative review of non-pharmaceutical behavioural measures for the prevention of COVID-19 (SARS-CoV-2) based on the Health-EDRM framework

    Chan, Emily Ying Yang / Shahzada, Tayyab Salim / Sham, Tiffany Sze Tung / Dubois, Caroline / Huang, Zhe / Liu, Sida / Ho, Janice Ying-En / Hung, Kevin K C / Kwok, Kin On / Shaw, Rajib

    Br. med. bull

    Abstract: INTRODUCTION: Non-pharmaceutical measures to facilitate a response to the COVID-19 pandemic, a disease caused by novel coronavirus SARS-CoV-2, are urgently needed. Using the World Health Organization (WHO) health emergency and disaster risk management ( ... ...

    Abstract INTRODUCTION: Non-pharmaceutical measures to facilitate a response to the COVID-19 pandemic, a disease caused by novel coronavirus SARS-CoV-2, are urgently needed. Using the World Health Organization (WHO) health emergency and disaster risk management (health-EDRM) framework, behavioural measures for droplet-borne communicable diseases and their enabling and limiting factors at various implementation levels were evaluated. SOURCES OF DATA: Keyword search was conducted in PubMed, Google Scholar, Embase, Medline, Science Direct, WHO and CDC online publication databases. Using the Oxford Centre for Evidence-Based Medicine review criteria, 10 bottom-up, non-pharmaceutical prevention measures from 104 English-language articles, which published between January 2000 and May 2020, were identified and examined. AREAS OF AGREEMENT: Evidence-guided behavioural measures against transmission of COVID-19 in global at-risk communities were identified, including regular handwashing, wearing face masks and avoiding crowds and gatherings. AREAS OF CONCERN: Strong evidence-based systematic behavioural studies for COVID-19 prevention are lacking. GROWING POINTS: Very limited research publications are available for non-pharmaceutical measures to facilitate pandemic response. AREAS TIMELY FOR RESEARCH: Research with strong implementation feasibility that targets resource-poor settings with low baseline health-EDRM capacity is urgently needed.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #838155
    Database COVID19

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  8. Article ; Online: Narrative review of non-pharmaceutical behavioural measures for the prevention of COVID-19 (SARS-CoV-2) based on the Health-EDRM framework

    Yang Chan, Emily Ying / Shahzada, Tayyab Salim / Sham, Tiffany Sze Tung / Dubois, Caroline / Huang, Zhe / Liu, Sida / Ho, Janice Ying-en / Hung, Kevin K C / Kwok, Kin On / Shaw, Rajib

    British Medical Bulletin ; ISSN 0007-1420 1471-8391

    2020  

    Abstract: Abstract Introduction Non-pharmaceutical measures to facilitate a response to the COVID-19 pandemic, a disease caused by novel coronavirus SARS-CoV-2, are urgently needed. Using the World Health Organization (WHO) health emergency and disaster risk ... ...

    Abstract Abstract Introduction Non-pharmaceutical measures to facilitate a response to the COVID-19 pandemic, a disease caused by novel coronavirus SARS-CoV-2, are urgently needed. Using the World Health Organization (WHO) health emergency and disaster risk management (health-EDRM) framework, behavioural measures for droplet-borne communicable diseases and their enabling and limiting factors at various implementation levels were evaluated. Sources of data Keyword search was conducted in PubMed, Google Scholar, Embase, Medline, Science Direct, WHO and CDC online publication databases. Using the Oxford Centre for Evidence-Based Medicine review criteria, 10 bottom-up, non-pharmaceutical prevention measures from 104 English-language articles, which published between January 2000 and May 2020, were identified and examined. Areas of agreement Evidence-guided behavioural measures against transmission of COVID-19 in global at-risk communities were identified, including regular handwashing, wearing face masks and avoiding crowds and gatherings. Areas of concern Strong evidence-based systematic behavioural studies for COVID-19 prevention are lacking. Growing points Very limited research publications are available for non-pharmaceutical measures to facilitate pandemic response. Areas timely for research Research with strong implementation feasibility that targets resource-poor settings with low baseline health-EDRM capacity is urgently needed.
    Keywords General Medicine ; covid19
    Language English
    Publisher Oxford University Press (OUP)
    Publishing country uk
    Document type Article ; Online
    DOI 10.1093/bmb/ldaa030
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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