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  1. Article: Use of Multiple Doses of Intravenous Infusion of Umbilical Cord-Mesenchymal Stem Cells for the Treatment of Adult Patients with Severe COVID-19-Related Acute Respiratory Distress Syndrome: Literature Review.

    Hsueh, Po-Ren / Ho, Sung-Jung / Hsieh, Po-Chuen / Liu, I-Min / Jean, Shio-Shin

    Stem cells international

    2023  Volume 2023, Page(s) 7179592

    Abstract: Objectives: Acute respiratory distress syndrome (ARDS) is a critical complication in severe COVID-19 patients. The intravenous infusion (IVF) of umbilical cord- (UC-) mesenchymal stem cells (MSCs), validated to substantially reduce the release of ... ...

    Abstract Objectives: Acute respiratory distress syndrome (ARDS) is a critical complication in severe COVID-19 patients. The intravenous infusion (IVF) of umbilical cord- (UC-) mesenchymal stem cells (MSCs), validated to substantially reduce the release of several inflammatory cytokines
    Methods: We reviewed the 2020-2022 PubMed literature database concerning the clinical efficacy of IVF-UC-MSCs among severe COVID-19 patients.
    Results: The data of COVID-19 case series in the PubMed literature revealed a notable heterogeneity in the therapeutic dosage (a single dose: 1-10 × 10
    Conclusions: According to our analysis, the ideal treatment dosage of IVF-UC-MSCs for severe COVID-19-induced ARDS is likely 5 × 10
    Language English
    Publishing date 2023-08-18
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2573856-2
    ISSN 1687-9678 ; 1687-966X
    ISSN (online) 1687-9678
    ISSN 1687-966X
    DOI 10.1155/2023/7179592
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Successful treatment of tocilizumab and ivermectin for a patient with ARDS due to COVID-19.

    Chuang, Tzu-Yi / Tsai, Ming-Han / Wu, Lit-Min / Ho, Sung-Jung / Yeh, Pu-Sheng / Liu, Yi-Lien / Fred Yang, Hung-Jen

    Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi

    2020  

    Language English
    Publishing date 2020-10-03
    Publishing country England
    Document type Letter
    ZDB-ID 1497590-7
    ISSN 1995-9133 ; 1684-1182 ; 0253-2662
    ISSN (online) 1995-9133
    ISSN 1684-1182 ; 0253-2662
    DOI 10.1016/j.jmii.2020.09.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.B 2083: Show issues Location:
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  3. Article: Successful treatment of tocilizumab and ivermectin for a patient with ARDS due to COVID-19

    Chuang, Tzu-Yi / Tsai, Ming-Han / Wu, Lit-Min / Ho, Sung-Jung / Yeh, Pu-Sheng / Liu, Yi-Lien / Fred Yang, Hung-Jen

    Journal of Microbiology, Immunology and Infection

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #813698
    Database COVID19

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  4. Article ; Online: Successful treatment of tocilizumab and ivermectin for a patient with ARDS due to COVID-19

    Chuang, Tzu-Yi / Tsai, Ming-Han / Wu, Lit-Min / Ho, Sung-Jung / Yeh, Pu-Sheng / Liu, Yi-Lien / Fred Yang, Hung-Jen

    Journal of Microbiology, Immunology and Infection ; ISSN 1684-1182

    2020  

    Keywords Immunology and Allergy ; Microbiology (medical) ; General Immunology and Microbiology ; Infectious Diseases ; General Medicine ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    DOI 10.1016/j.jmii.2020.09.007
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article: Fatal community-acquired pneumonia caused by Legionella pneumophila and fluoroquinolone-resistant Salmonella enterica serotype Choleraesuis bacteraemia.

    Jean, Shio-Shin / Tsai, Ming-Han / Chen, Wan-Chin / Ho, Sung-Jung / Wu, Ming-Hsun / Hsueh, Po-Ren

    International journal of antimicrobial agents

    2009  Volume 33, Issue 2, Page(s) 189–190

    MeSH term(s) Aged ; Anti-Bacterial Agents/pharmacology ; Bacteremia/microbiology ; Community-Acquired Infections/microbiology ; Drug Resistance, Bacterial ; Fatal Outcome ; Fluoroquinolones/pharmacology ; Humans ; Legionella pneumophila/drug effects ; Legionella pneumophila/isolation & purification ; Legionnaires' Disease/diagnosis ; Legionnaires' Disease/microbiology ; Male ; Radiography, Thoracic ; Salmonella/drug effects ; Salmonella/isolation & purification ; Salmonella Infections/diagnosis ; Salmonella Infections/microbiology
    Chemical Substances Anti-Bacterial Agents ; Fluoroquinolones
    Language English
    Publishing date 2009-02
    Publishing country Netherlands
    Document type Case Reports ; Letter
    ZDB-ID 1093977-5
    ISSN 1872-7913 ; 0924-8579
    ISSN (online) 1872-7913
    ISSN 0924-8579
    DOI 10.1016/j.ijantimicag.2008.08.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 3368: Show issues Location:
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    Zs.MO 500: Show issues

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  6. Article ; Online: Clinical predictors of obstructive sleep apnea in Asian bariatric patients.

    Yeh, Pu-Sheng / Lee, Yi-Chih / Lee, Wei-Jei / Chen, Sheng-Bin / Ho, Sung-Jung / Peng, Wei-Ban / Tsao, Ching-Ching / Chiu, Hui-Ling

    Obesity surgery

    2009  Volume 20, Issue 1, Page(s) 30–35

    Abstract: Background: Obstructive sleep apnea (OSA) is a common disorder in modern society and closely associated with obesity. Because OSA increases the likelihood of complications in the perioperative period, preoperative recognition is very important for ... ...

    Abstract Background: Obstructive sleep apnea (OSA) is a common disorder in modern society and closely associated with obesity. Because OSA increases the likelihood of complications in the perioperative period, preoperative recognition is very important for bariatric patients. Polysomnography (PSG) remains the gold standard for diagnosis, but it is a time-consuming and expensive examination. Our study is aimed at identifying practical clinical predictors of OSA for bariatric patients.
    Methods: From April 2006 to December 2007, 101 morbid obese patients [41 men and 60 women, mean age 30.3 +/- 8.5, mean body mass index (BMI) 43.3 +/- 6.9] who underwent PSG before bariatric surgery were retrospectively studied. The severity of OSA was categorized by the apnea-hypopnea index (AHI) as follows: normal, 0 to 4.9; mild, 5 to 14.9; moderate, 15 to 29.9; and severe, >/=30. Chi-squared tests and linear regression models were used to assess associations between clinical parameters and AHI; P < 0.05 was considered statistically significant.
    Results: The mean Epworth sleepiness scale (ESS) score was 8.2 +/- 4.7, and the mean AHI was 28.9 +/- 33.8 per hour. Of 101 patients, 83 patients had OSA; including severe (32.7%), moderate (17.8%), and mild (31.7%) OSA; 18.5% had no OSA. Patients with severe OSA are significantly male predominant and had higher BMI, systolic blood pressure, hemoglobin, neck and waist circumference, and ESS scores. In linear regression model analysis, the parameters which positively correlated with AHI were body weight, BMI, systolic blood pressure, diastolic blood pressure, hemoglobin, waist and neck circumferences, and the scores of ESS. Multivariate analysis confirmed that BMI, neck circumference, and scores of ESS are independent predictors of the increasing of AHI.
    Conclusions: OSA is highly prevalent (82.2%) in Asian bariatric patients. BMI, neck circumference, and scores of ESS are independent predictors of OSA in these patients.
    MeSH term(s) Adult ; Body Mass Index ; Comorbidity ; Female ; Humans ; Male ; Multivariate Analysis ; Neck/anatomy & histology ; Obesity, Morbid/epidemiology ; Obesity, Morbid/surgery ; Polysomnography ; Risk Factors ; Sleep Apnea, Obstructive/diagnosis ; Sleep Apnea, Obstructive/epidemiology ; Taiwan/epidemiology ; Young Adult
    Language English
    Publishing date 2009-05-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1070827-3
    ISSN 1708-0428 ; 0960-8923
    ISSN (online) 1708-0428
    ISSN 0960-8923
    DOI 10.1007/s11695-009-9854-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 3381: Show issues Location:
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  7. Article: Initial otolaryngological manifestations of severe acute respiratory syndrome in Taiwan.

    Chen, Hsin-Chi / Young, Yi-Ho / Luo, Jyh-Perng / Tsai, Hui-Ju / Ho, Sung-Jung / Yeh, Chi-Huang / Huang, Lien-Chi

    Archives of otolaryngology--head & neck surgery

    2003  Volume 129, Issue 11, Page(s) 1157–1160

    Abstract: Objective: To provide a clue for screening severe acute respiratory syndrome (SARS), a highly transmissible disease with health care workers at particular risk, in the early stage from an otolaryngological perspective.: Design: Prospective study.: ... ...

    Abstract Objective: To provide a clue for screening severe acute respiratory syndrome (SARS), a highly transmissible disease with health care workers at particular risk, in the early stage from an otolaryngological perspective.
    Design: Prospective study.
    Setting: Community hospital.
    Patients: Between April 17 and April 26, 2003, 32 consecutive patients with SARS were encountered. Investigation consisted of local examination of ear, nose, and throat fields; palpation of the nuchal areas; and plain chest radiography. Analyses of throat swab samples using reverse transcription-polymerase chain reaction were conducted.
    Results: Clinical manifestations included fever in 31 patients (97%), followed by cough, dyspnea, chill, headache, sore throat, diarrhea, rhinorrhea, and otalgia. Neither the pharyngeal wall nor the tonsillar area demonstrated hyperemia. There was no lymphadenopathy in the neck. Plain chest radiographs revealed consolidation in 25 (78%) of 32 patients. Results of reverse transcription-polymerase chain reaction analysis targeting the novel coronavirus present in throat swab samples were positive in 19 (66%) of 29 patients tested. Twenty-eight patients required supplemental oxygen, and 14 patients were intubated with mechanical ventilation. Twenty-eight patients survived and 4 patients died.
    Conclusions: When presented with a patient with flulike symptoms such as fever and/or cough, but no pharyngeal hyperemia or neck lymphadenopathy, physicians should be alerted to the possibility of SARS. In contrast, evidence of inflammatory signs in the otolaryngological field may explain the flulike symptoms, and serve as a differential diagnostic tool between influenza and SARS.
    MeSH term(s) Adolescent ; Adult ; Female ; Humans ; Influenza, Human/diagnosis ; Male ; Middle Aged ; Prospective Studies ; Severe Acute Respiratory Syndrome/complications ; Severe Acute Respiratory Syndrome/diagnosis ; Taiwan
    Keywords covid19
    Language English
    Publishing date 2003-11
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 632721-7
    ISSN 1538-361X ; 0886-4470 ; 2168-6181
    ISSN (online) 1538-361X
    ISSN 0886-4470 ; 2168-6181
    DOI 10.1001/archotol.129.11.1157
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