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  1. Article ; Online: We should no longer play lip service to lifestyle interventions in the prevention of CVD.

    Hobbs, Fd Richard

    European journal of internal medicine

    2020  Volume 78, Page(s) 6–7

    MeSH term(s) Cardiovascular Diseases ; Humans ; Life Style ; Risk Reduction Behavior
    Language English
    Publishing date 2020-06-20
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 1038679-8
    ISSN 1879-0828 ; 0953-6205
    ISSN (online) 1879-0828
    ISSN 0953-6205
    DOI 10.1016/j.ejim.2020.05.022
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  2. Article ; Online: Lessons from the English primary care sentinel network's response to the COVID-19 pandemic.

    de Lusignan, Simon / Hobbs, Fd Richard / Sheikh, Aziz

    The Lancet. Infectious diseases

    2023  Volume 24, Issue 1, Page(s) 14–16

    MeSH term(s) Humans ; Pandemics ; COVID-19 ; Primary Health Care
    Language English
    Publishing date 2023-11-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2061641-7
    ISSN 1474-4457 ; 1473-3099
    ISSN (online) 1474-4457
    ISSN 1473-3099
    DOI 10.1016/S1473-3099(23)00736-3
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  3. Book: Cardiovascular risk management

    Hobbs, Richard

    2009  

    Author's details ed. by Richard Hobbs
    Keywords Cardiovascular Diseases / prevention & control ; Risk Assessment
    Language English
    Size X, 90 S. : Ill., graph. Darst.
    Publisher Wiley-Blackwell
    Publishing place Chichester u.a.
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT015890291
    ISBN 978-1-4051-5575-5 ; 1-4051-5575-2
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    2009 A 1455 order for loan Magazin

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  4. Article ; Online: Are more GPs associated with a reduction in emergency hospital admissions? A quantitative study on GP referral in England.

    Nicodemo, Catia / McCormick, Barry / Wittenberg, Raphael / Hobbs, Fd Richard

    The British journal of general practice : the journal of the Royal College of General Practitioners

    2021  Volume 71, Issue 705, Page(s) e287–e295

    Abstract: Background: Recent studies have found an association between access to primary care and accident and emergency attendances, with better access associated with fewer attendances. Analyses of an association with emergency admissions, however, have ... ...

    Abstract Background: Recent studies have found an association between access to primary care and accident and emergency attendances, with better access associated with fewer attendances. Analyses of an association with emergency admissions, however, have produced conflicting findings.
    Aim: This study investigated whether emergency admission rates in an area are associated with 1) the number of GPs, and 2) mean size of GP practice.
    Design and setting: Analysis was conducted utilising Hospital Episode Statistics, the numbers of GPs and GP practices, Office for National Statistics population data, Quality and Outcomes Framework prevalence data, and Index of Multiple Deprivation data, from 2004/2005 to 2011/2012, for all practices in England.
    Method: Regression analysis of panel data with fixed effects to address 1) a potential two-way relationship between the numbers of GPs and emergency admissions, and 2) unobservable characteristics of GP practices.
    Results: There is not a statistically significant relationship between the number of GPs in a primary care trust area and the number of emergency admissions, when analysing all areas. In deprived areas, however, a higher number of GPs is associated with lower emergency admissions. There is also a lower emergency admission rate in areas in which practices are on average larger, holding GP supply constant.
    Conclusion: An increase in GPs was found to reduce emergency admissions in deprived areas, but not elsewhere. Areas in which GPs are concentrated into larger practices showed reduced levels of emergency admissions, all else being equal.
    MeSH term(s) Emergency Service, Hospital ; England/epidemiology ; Hospitalization ; Hospitals ; Humans ; Referral and Consultation
    Language English
    Publishing date 2021-03-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 1043148-2
    ISSN 1478-5242 ; 0035-8797 ; 0960-1643
    ISSN (online) 1478-5242
    ISSN 0035-8797 ; 0960-1643
    DOI 10.3399/BJGP.2020.0737
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  5. Article ; Online: FASTer diagnosis: Time to BEAT heart failure.

    Taylor, Clare J / Hartshorne-Evans, Nick / Satchithananda, Duwarakan / Hobbs, Fd Richard

    BJGP open

    2021  Volume 5, Issue 3

    Language English
    Publishing date 2021-06-30
    Publishing country England
    Document type Journal Article
    ISSN 2398-3795
    ISSN (online) 2398-3795
    DOI 10.3399/BJGPO.2021.0006
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  6. Article ; Online: Beyond COVID-19: respiratory infection and cardiovascular events.

    Lee, Joseph J / Koshiaris, Constantinos / Hobbs, Fd Richard / Sheppard, James P

    The British journal of general practice : the journal of the Royal College of General Practitioners

    2021  Volume 71, Issue 709, Page(s) 342–343

    MeSH term(s) COVID-19 ; Cardiovascular Diseases ; Humans ; Respiratory Tract Infections/diagnosis ; SARS-CoV-2
    Language English
    Publishing date 2021-07-29
    Publishing country England
    Document type Editorial
    ZDB-ID 1043148-2
    ISSN 1478-5242 ; 0035-8797 ; 0960-1643
    ISSN (online) 1478-5242
    ISSN 0035-8797 ; 0960-1643
    DOI 10.3399/bjgp21X716477
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  7. Article ; Online: Face masks while exercising trial (MERIT): a cross-over randomised controlled study.

    Jones, Nicholas / Oke, Jason / Marsh, Seren / Nikbin, Kurosh / Bowley, Jonathan / Dijkstra, H Paul / Hobbs, Fd Richard / Greenhalgh, Trisha

    BMJ open

    2023  Volume 13, Issue 1, Page(s) e063014

    Abstract: Objectives: Physical exertion is a high-risk activity for aerosol emission of respiratory pathogens. We aimed to determine the safety and tolerability of healthy young adults wearing different types of face mask during moderate-to-high intensity ... ...

    Abstract Objectives: Physical exertion is a high-risk activity for aerosol emission of respiratory pathogens. We aimed to determine the safety and tolerability of healthy young adults wearing different types of face mask during moderate-to-high intensity exercise.
    Design: Cross-over randomised controlled study, completed between June 2021 and January 2022.
    Participants: Volunteers aged 18-35 years, who exercised regularly and had no significant pre-existing health conditions.
    Interventions: Comparison of wearing a surgical, cloth and filtering face piece (FFP3) mask to no mask during 4×15 min bouts of exercise. Exercise was running outdoors or indoor rowing at moderate-to-high intensity, with consistency of distance travelled between bouts confirmed using a smartphone application (Strava). Each participant completed each bout in random order.
    Outcomes: The primary outcome was change in oxygen saturations. Secondary outcomes were change in heart rate, perceived impact of face mask wearing during exercise and willingness to wear a face mask for future exercise.
    Results: All 72 volunteers (mean age 23.9) completed the study. Changes in oxygen saturations did not exceed the prespecified non-inferiority margin (2% difference) with any mask type compared with no mask. At the end of exercise, the estimated average difference in oxygen saturations for cloth mask was -0.07% (95% CI -0.39% to 0.25%), for surgical 0.28% (-0.04% to 0.60%) and for FFP3 -0.21% (-0.53% to 0.11%). The corresponding estimated average difference in heart rate for cloth mask was -1.20 bpm (95% CI -4.56 to 2.15), for surgical 0.36 bpm (95% CI -3.01 to 3.73) and for FFP3 0.52 bpm (95% CI -2.85 to 3.89). Wearing a face mask caused additional symptoms such as breathlessness (n=13, 18%) and dizziness (n=7, 10%). 33 participants broadly supported face mask wearing during exercise, particularly indoors, but 22 were opposed.
    Conclusion: This study adds to previous findings (mostly from non-randomised studies) that exercising at moderate-to-high intensity wearing a face mask appears to be safe in healthy, young adults.
    Trial registration number: NCT04932226.
    MeSH term(s) Young Adult ; Humans ; Adult ; COVID-19/prevention & control ; Masks ; Exercise ; Cross-Over Studies ; Oxygen
    Chemical Substances Oxygen (S88TT14065)
    Language English
    Publishing date 2023-01-05
    Publishing country England
    Document type Randomized Controlled Trial ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2599832-8
    ISSN 2044-6055 ; 2044-6055
    ISSN (online) 2044-6055
    ISSN 2044-6055
    DOI 10.1136/bmjopen-2022-063014
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  8. Article ; Online: Effectiveness of exhaled nitric oxide for the prediction of non-invasive left atrial pressure in older people: a cross-sectional cohort study.

    Jones, Samuel Thomas / Londahl, Monica / Prothero, Anthony / Hobbs, Fd Richard / Pavord, Ian / Myerson, Saul G / Prendergast, Bernard D / Coffey, Sean

    BJGP open

    2023  Volume 7, Issue 1

    Abstract: Background: During left-sided heart failure (HF), left atrial and pulmonary venous pressure increase, which may lead to pulmonary congestion. Previous cohort studies, examining participants with symptomatic HF or rheumatic heart disease, suggest a ... ...

    Abstract Background: During left-sided heart failure (HF), left atrial and pulmonary venous pressure increase, which may lead to pulmonary congestion. Previous cohort studies, examining participants with symptomatic HF or rheumatic heart disease, suggest a relationship between increased left atrial pressure (LAP) and fractional exhaled nitric oxide (FeNO).
    Aim: To examine the strength of association between FeNO and echocardiographic assessment of LAP by the E/e' ratio, to determine if FeNO could be used to identify those with elevated LAP.
    Design & setting: This cross-sectional cohort study examined a subset of the OxVALVE cohort aged ≥65 years. Data collection was undertaken in primary care practices in central England.
    Method: Each participant underwent a focused cardiovascular history and clinical examination. Standard transthoracic echocardiographic (TTE) assessment was performed on all participants, with the E/e' ratio calculated to obtain a validated surrogate of LAP. FeNO was measured in 227 participants.
    Results: FeNO was higher in males compared with females and no different in participants with asthma, chronic obstructive pulmonary disease (COPD), or those using inhaled steroids. Participants with a high E/e' (>14) were older, with a higher proportion of females than males. There was no relationship between E/e' and FeNO, either when measured as a continuous variable or in the group with high E/e'.
    Conclusion: FeNO was not found to be an accurate predictor of elevated LAP in a primary care setting.
    Language English
    Publishing date 2023-03-21
    Publishing country England
    Document type Journal Article
    ISSN 2398-3795
    ISSN (online) 2398-3795
    DOI 10.3399/BJGPO.2022.0105
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  9. Article ; Online: Body mass index and survival in people with heart failure.

    Jones, Nicholas R / Ordóñez-Mena, José M / Roalfe, Andrea K / Taylor, Kathryn S / Goyder, Clare R / Hobbs, Fd Richard / Taylor, Clare J

    Heart (British Cardiac Society)

    2023  Volume 109, Issue 20, Page(s) 1542–1549

    Abstract: Aims: In people with heart failure (HF), a high body mass index (BMI) has been linked with better outcomes ('obesity paradox'), but there is limited evidence in community populations across long-term follow-up. We aimed to examine the association ... ...

    Abstract Aims: In people with heart failure (HF), a high body mass index (BMI) has been linked with better outcomes ('obesity paradox'), but there is limited evidence in community populations across long-term follow-up. We aimed to examine the association between BMI and long-term survival in patients with HF in a large primary care cohort.
    Methods: We included patients with incident HF aged ≥45 years from the Clinical Practice Research Datalink (2000-2017). We used Kaplan-Meier curves, Cox regression and penalised spline methods to assess the association of pre-diagnostic BMI, based on WHO classification, with all-cause mortality.
    Results: There were 47 531 participants with HF (median age 78.0 years (IQR 70-84), 45.8% female, 79.0% white ethnicity, median BMI 27.1 (IQR 23.9-31.0)) and 25 013 (52.6%) died during follow-up. Compared with healthy weight, people with overweight (HR 0.78, 95% CI 0.75 to 0.81, risk difference (RD) -4.1%), obesity class I (HR 0.76, 95% CI 0.73 to 0.80, RD -4.5%) and class II (HR 0.76, 95% CI 0.71 to 0.81, RD -4.5%) were at decreased risk of death, whereas people with underweight were at increased risk (HR 1.59, 95% CI 1.45 to 1.75, RD 11.2%). In those underweight, this risk was greater among men than women (p value for interaction=0.02). Class III obesity was associated with increased risk of all-cause mortality compared with overweight (HR 1.23, 95% CI 1.17 to 1.29).
    Conclusion: The U-shaped relationship between BMI and long-term all-cause mortality suggests a personalised approach to identifying optimal weight may be needed for patients with HF in primary care. Underweight people have the poorest prognosis and should be recognised as high-risk.
    MeSH term(s) Male ; Humans ; Female ; Aged ; Overweight/complications ; Body Mass Index ; Thinness/complications ; Thinness/epidemiology ; Heart Failure ; Obesity/complications ; Obesity/epidemiology ; Obesity/diagnosis ; Risk Factors
    Language English
    Publishing date 2023-09-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 1303417-0
    ISSN 1468-201X ; 1355-6037
    ISSN (online) 1468-201X
    ISSN 1355-6037
    DOI 10.1136/heartjnl-2023-322459
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  10. Article ; Online: The Stern review of the Research Excellence Framework.

    Hobbs, Fd Richard / Roberts, Lesley M

    BMJ (Clinical research ed.)

    2016  Volume 354, Page(s) i4413

    MeSH term(s) Biomedical Research/economics ; Biomedical Research/standards ; Financing, Government ; Humans ; Quality Assurance, Health Care/methods ; Research Support as Topic/economics ; Research Support as Topic/organization & administration ; United Kingdom ; Universities/economics ; Universities/standards
    Language English
    Publishing date 2016--15
    Publishing country England
    Document type Editorial
    ZDB-ID 1362901-3
    ISSN 1756-1833 ; 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    ISSN (online) 1756-1833
    ISSN 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    DOI 10.1136/bmj.i4413
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