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  1. Article ; Online: Nonsuperiority of Standard Therapy Compared to Short-Course Therapy in Symptomatic UTIs-Reply.

    Shaikh, Nader / Hoberman, Alejandro

    JAMA pediatrics

    2023  Volume 177, Issue 12, Page(s) 1361

    MeSH term(s) Humans ; Urinary Tract Infections/diagnosis ; Urinary Tract Infections/drug therapy ; Anti-Bacterial Agents/therapeutic use
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2023-10-09
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2701223-2
    ISSN 2168-6211 ; 2168-6203
    ISSN (online) 2168-6211
    ISSN 2168-6203
    DOI 10.1001/jamapediatrics.2023.4059
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Antibiotic Receipt for Pediatric Telemedicine Visits With Primary Care vs Direct-to-Consumer Vendors.

    Wittman, Samuel R / Hoberman, Alejandro / Mehrotra, Ateev / Sabik, Lindsay M / Yabes, Jonathan G / Ray, Kristin N

    JAMA network open

    2024  Volume 7, Issue 3, Page(s) e242359

    Abstract: Importance: Prior research found that pediatric direct-to-consumer (DTC) telemedicine visits are associated with more antibiotic prescribing than in-person primary care visits. It is unclear whether this difference is associated with modality of care ( ... ...

    Abstract Importance: Prior research found that pediatric direct-to-consumer (DTC) telemedicine visits are associated with more antibiotic prescribing than in-person primary care visits. It is unclear whether this difference is associated with modality of care (telemedicine vs in-person) or with the context of telemedicine care (primary care vs not primary care).
    Objective: To compare antibiotic management during telemedicine visits with primary care practitioners (PCPs) vs commercial direct-to-consumer (DTC) telemedicine companies for pediatric acute respiratory tract infections (ARTIs).
    Design, setting, and participants: This retrospective, cross-sectional study of visits for ARTIs by commercially insured children 17 years of age or younger analyzed deidentified medical and pharmacy claims in OptumLabs Data Warehouse data, a national sample of commercial enrollees, between January 1 and December 31, 2022.
    Exposure: Setting of telemedicine visit as PCP vs DTC.
    Main outcomes and measures: The primary outcome was percentage of visits with antibiotic receipt. Secondary outcomes were the percentages of visits with diagnoses for which prescription of an antibiotic was potentially appropriate, guideline-concordant antibiotic management, and follow-up ARTI visits within the ensuing 1 to 2 days and 3 to 14 days. The ARTI telemedicine visits with PCP vs DTC telemedicine companies were matched on child demographic characteristics. Generalized estimated equation log-binomial regression models were used to compute marginal outcomes.
    Results: In total, data from 27 686 children (mean [SD] age, 8.9 [5.0] years; 13 893 [50.2%] male) were included in this study. There were 14 202 PCP telemedicine index visits matched to 14 627 DTC telemedicine index visits. The percentage of visits involving receipt of an antibiotic was lower for PCP (28.9% [95% CI, 28.1%-29.7%]) than for DTC (37.2% [95% CI, 36.0%-38.5%]) telemedicine visits. Additionally, fewer PCP telemedicine visits involved receipt of a diagnosis in which the use of antibiotics may be appropriate (19.0% [95% CI, 18.4%-19.7%] vs 28.4% [95% CI, 27.3%-29.6%]), but no differences were observed in receipt of nonguideline-concordant antibiotic management based on a given diagnosis between PCP (20.2% [95% CI, 19.5%-20.9%]) and DTC (20.1% [95% CI, 19.1%-21.0%]) telemedicine visits. Fewer PCP telemedicine visits involved a follow-up visit within the ensuing 1 to 2 days (5.0% [95% CI, 4.7%-5.4%] vs 8.0% [95% CI, 7.3%-8.7%]) and 3 to 14 days (8.2% [95% CI, 7.8%-8.7%] vs 9.6% [95% CI, 8.8%-10.3%]).
    Conclusions and relevance: Compared with virtual-only DTC telemedicine companies, telemedicine integrated within primary care was associated with lower rates of antibiotic receipt and follow-up care. Supporting use of telemedicine integrated within pediatric primary care may be one strategy to reduce antibiotic receipt through telemedicine visits.
    MeSH term(s) Humans ; Child ; Male ; Female ; Cross-Sectional Studies ; Retrospective Studies ; Anti-Bacterial Agents/therapeutic use ; Respiratory Tract Infections/drug therapy ; Telemedicine ; Primary Health Care
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2024-03-04
    Publishing country United States
    Document type Journal Article
    ISSN 2574-3805
    ISSN (online) 2574-3805
    DOI 10.1001/jamanetworkopen.2024.2359
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: More Recent Literature Does Not Support Premise or Conclusions.

    Shope, Timothy R / Shaikh, Nader / Hoberman, Alejandro

    JAMA pediatrics

    2022  Volume 176, Issue 8, Page(s) 826–827

    Language English
    Publishing date 2022-06-10
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 2701223-2
    ISSN 2168-6211 ; 2168-6203
    ISSN (online) 2168-6211
    ISSN 2168-6203
    DOI 10.1001/jamapediatrics.2022.1760
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Tympanostomy Tubes for Recurrent Otitis Media.

    Lee, Clement / Preciado, Diego / Hoberman, Alejandro

    The New England journal of medicine

    2022  Volume 387, Issue 1, Page(s) 83–85

    MeSH term(s) Humans ; Middle Ear Ventilation/instrumentation ; Otitis Media/surgery ; Otitis Media with Effusion/surgery ; Recurrence
    Language English
    Publishing date 2022-07-06
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMclde2202050
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: The research home: partnering with families.

    Hoberman, Alejandro

    Academic pediatrics

    2014  Volume 14, Issue 6, Page(s) 549–553

    MeSH term(s) Awards and Prizes ; Biomedical Research ; Family ; Humans ; Patient-Centered Care ; Pediatrics ; Periodicals as Topic ; United States
    Language English
    Publishing date 2014-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2483385-X
    ISSN 1876-2867 ; 1876-2859
    ISSN (online) 1876-2867
    ISSN 1876-2859
    DOI 10.1016/j.acap.2014.08.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Parent Perceptions of Telemedicine for Acute Pediatric Respiratory Tract Infections: Sequential Mixed Methods Study.

    Burns, Sarah K / Krishnamurti, Tamar / Doan, Tran T / Hanmer, Janel / Hoberman, Alejandro / Kahn, Jeremy M / Schweiberger, Kelsey / Ray, Kristin N

    JMIR pediatrics and parenting

    2024  Volume 7, Page(s) e49170

    Abstract: Background: Since 2020, parents have had increasing opportunities to use telemedicine for their children, but how parents decide whether to use telemedicine for acute pediatric care relative to alternative sites of care is not clear. One of the most ... ...

    Abstract Background: Since 2020, parents have had increasing opportunities to use telemedicine for their children, but how parents decide whether to use telemedicine for acute pediatric care relative to alternative sites of care is not clear. One of the most common reasons parents seek acute care for their children is for acute respiratory tract infections (ARTIs).
    Objective: This study aims to examine parental expectations of care via telemedicine for pediatric ARTIs, contrasting expectations of care delivered via primary care telemedicine and direct-to-consumer (DTC) telemedicine.
    Methods: We performed a sequential mixed methods analysis to examine how parents assess telemedicine for their children's acute care. We used ARTIs as a case study for examining parent perceptions of telemedicine. First, we analyzed semistructured interviews focused on parent responses about the use of telemedicine. Each factor discussed by parents was coded to reflect whether parents indicated it incentivized or disincentivized their preferences for telemedicine versus in-person care. Results were organized by a 7-dimension framework of parental health care seeking that was generated previously, which included dimensions related to care sites (expected access, affordability, clinical quality, and site quality) and dimensions related to child or family factors (perceived illness severity, perceived child susceptibility, and parent self-efficacy). Second, we analyzed responses to a national survey, which inquired about parental expectations of primary care telemedicine, commercial DTC telemedicine, and 3 in-person sites of care (primary care, urgent care, and emergency department) across 21 factors identified through prior qualitative work. To assess whether parents had different expectations of different telemedicine models, we compared survey responses for primary care telemedicine and commercial DTC telemedicine using weighted logistic regression.
    Results: Interview participants (n=40) described factors affecting their perceptions of telemedicine as a care modality for pediatric ARTIs. Generally, factors aligned with access and affordability (eg, decreased wait time and lower out-of-pocket cost) were discussed as potential incentives for telemedicine use, while factors aligned with perceived illness severity, child susceptibility, and clinician quality (eg, trustworthiness) were discussed as potential disincentives for telemedicine use. In survey responses (n=1206), primary care and commercial DTC telemedicine were rated similarly on items related to expected accessibility and affordability. In contrast, on items related to expected quality of care, primary care telemedicine was viewed similarly to in-person primary care, while commercial DTC telemedicine was rated lower. For example, 69.7% (weighted; 842/1197) of respondents anticipated their children would be comfortable and cooperative with primary care telemedicine versus 49.7% (weighted; 584/1193) with commercial DTC telemedicine (P<.001).
    Conclusions: In a mixed methods analysis focused on telemedicine for ARTIs, parents expressed more concerns about telemedicine quality in commercial DTC models compared with primary care-based telemedicine. These results could help health systems better design telemedicine initiatives to support family-centered care.
    Language English
    Publishing date 2024-01-16
    Publishing country Canada
    Document type Journal Article
    ISSN 2561-6722
    ISSN (online) 2561-6722
    DOI 10.2196/49170
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Tympanostomy Tubes or Medical Management for Recurrent Acute Otitis Media. Reply.

    Paradise, Jack L / Hoberman, Alejandro / Preciado, Diego

    The New England journal of medicine

    2021  Volume 385, Issue 9, Page(s) 861–862

    MeSH term(s) Chronic Disease ; Humans ; Middle Ear Ventilation ; Otitis Media/drug therapy ; Otitis Media with Effusion
    Language English
    Publishing date 2021-08-26
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMc2109725
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Pediatric Primary Care Clinicians' Perspectives on Telemedicine Use, 2020 Versus 2021.

    Schweiberger, Kelsey / Hoberman, Alejandro / Iagnemma, Jennifer / Schoemer, Pamela / White, Gretchen E / Wolfson, David / Ray, Kristin N

    Telemedicine journal and e-health : the official journal of the American Telemedicine Association

    2024  

    Abstract: Objective: ...

    Abstract Objective:
    Language English
    Publishing date 2024-04-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2035659-6
    ISSN 1556-3669 ; 1530-5627
    ISSN (online) 1556-3669
    ISSN 1530-5627
    DOI 10.1089/tmj.2023.0507
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Cost-Effectiveness of Management Strategies in Recurrent Acute Otitis Media.

    Noorbakhsh, Kathleen A / Liu, Hui / Kurs-Lasky, Marcia / Smith, Kenneth J / Hoberman, Alejandro / Shaikh, Nader

    The Journal of pediatrics

    2022  Volume 256, Page(s) 11–17.e2

    Abstract: Objective: To evaluate the cost-effectiveness of tympanostomy tube placementvs nonsurgical medical management, with the option of tympanostomy tube placement in the event of treatment failure, in children with recurrent acute otitis media (AOM).: ... ...

    Abstract Objective: To evaluate the cost-effectiveness of tympanostomy tube placementvs nonsurgical medical management, with the option of tympanostomy tube placement in the event of treatment failure, in children with recurrent acute otitis media (AOM).
    Study design: A Markov decision model compared management strategies in children ages 6-35 months, using patient-level data from a recently completed, multicenter, randomized clinical trial of tympanostomy tube placement vs medical management. The model ran over a 2-year time horizon using a societal perspective. Probabilities, including risk of AOM symptoms, were derived from prospectively collected patient diaries. Costs and quality-of-life measures were derived from the literature. We performed one-way and probabilistic sensitivity analyses, and secondary analyses in predetermined low- and high-risk subgroups. The primary outcome was incremental cost per quality-adjusted life-year gained.
    Results: Tympanostomy tubes cost $989 more per child than medical management. Children managed with tympanostomy tubes gained 0.69 more quality-adjusted life-days than children managed medically, corresponding to $520 855 per quality-adjusted life-year gained. Results were sensitive to the costs of oral antibiotics, missed work, special childcare, the societal cost of antibiotic resistance, and the quality of life associated with AOM. In probabilistic sensitivity analyses, medical management was favored in 66% of model iterations at a willingness-to-pay threshold of $100 000/quality-adjusted life-year. Medical management was preferred in secondary analyses of low- and high-risk subgroups.
    Conclusions: For young children with recurrent AOM, the additional cost associated with tympanostomy tube placement outweighs the small improvement in quality of life. Medical management for these children is an economically reasonable strategy.
    Trial registration: ClinicalTrials.gov number, NCT02567825.
    MeSH term(s) Child ; Humans ; Infant ; Child, Preschool ; Cost-Benefit Analysis ; Quality of Life ; Neoplasm Recurrence, Local/drug therapy ; Neoplasm Recurrence, Local/surgery ; Otitis Media/therapy ; Otitis Media/diagnosis ; Anti-Bacterial Agents/therapeutic use ; Middle Ear Ventilation
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2022-12-05
    Publishing country United States
    Document type Randomized Controlled Trial ; Multicenter Study ; Journal Article
    ZDB-ID 3102-1
    ISSN 1097-6833 ; 0022-3476
    ISSN (online) 1097-6833
    ISSN 0022-3476
    DOI 10.1016/j.jpeds.2022.11.032
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Telemedicine Visits to Children During the Pandemic: Practice-Based Telemedicine Versus Telemedicine-Only Providers.

    Ray, Kristin N / Wittman, Samuel R / Yabes, Jonathan G / Sabik, Lindsay M / Hoberman, Alejandro / Mehrotra, Ateev

    Academic pediatrics

    2022  Volume 23, Issue 2, Page(s) 265–270

    Abstract: Objective: In March 2020, regulatory and payment changes allowed "brick and mortar" pediatric practices to offer practice-based telemedicine for the first time, joining direct-to-consumer (DTC) telemedicine vendors in the ability to offer visits for ... ...

    Abstract Objective: In March 2020, regulatory and payment changes allowed "brick and mortar" pediatric practices to offer practice-based telemedicine for the first time, joining direct-to-consumer (DTC) telemedicine vendors in the ability to offer visits for common acute pediatric concerns via telemedicine. We sought to characterize the relative contribution of practice-based telemedicine versus commercial DTC telemedicine models in provision of children's telemedicine from 2018 through 2021.
    Methods: Using January 2018 to September 2021 data from Optum's de-identified Clinformatics® Data Mart Database, we identified telemedicine visits by children ≤17, excluding preventive visits and visits to specialists, emergency departments, and urgent care. Among included visits, we defined "telemedicine-only" providers as those with ≥80% of visits via telemedicine and practice-based telemedicine providers as those with ≤50% of visits via telemedicine. We then described the telemedicine visit volume and diagnoses for these categories overall and per 1000 children per month.
    Results: From January 2018 to February 2020, telemedicine-only providers accounted for 57,815 telemedicine visits (90.8%), while practice-based telemedicine accounted for 4192 telemedicine visits (6.6%). From March 2020 to September 2021, telemedicine-only providers accounted for 38,282 telemedicine visits (6.1%), while practice-based telemedicine accounted for 555,125 telemedicine visits (88.2%). Per month, telemedicine visits to practice-based telemedicine providers increased from pre-pandemic to pandemic periods (0.1 vs 12.9 visits per 1000 children/month), while telemedicine visits to telemedicine-only providers occurred at a similar rate from pre-pandemic to pandemic periods (0.92 vs 0.96 visits per 1000 children/month).
    Conclusions: We observed a large increase in telemedicine visits during the pandemic, with the growth in visits exclusively occurring among visits to practice-based telemedicine providers as opposed to telemedicine-only providers.
    MeSH term(s) Humans ; Child ; COVID-19 ; Pandemics/prevention & control ; Telemedicine ; Ambulatory Care ; Databases, Factual
    Language English
    Publishing date 2022-05-16
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2483385-X
    ISSN 1876-2867 ; 1876-2859
    ISSN (online) 1876-2867
    ISSN 1876-2859
    DOI 10.1016/j.acap.2022.05.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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