LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Back to previous search Search history
Advanced search

Your last searches

  1. AU="Hofmann, Nina"
  2. AU="Kaleagasi, Hakan"
  3. AU="Giulianelli, G"
  4. AU="Sanoj Punnen"

Search results

Result 1 - 10 of total 50

Search options

  1. Book ; Thesis: Evaluation von Infarktgröße und Vorhersage myokardialer Funktionsverbesserung nach akutem Myokardinfarkt mittels quantitativer Blushgrade-Analyse im Herzkatheterlabor

    Hofmann, Nina

    2011  

    Author's details vorgelegt von Nina Patricia Hofmann
    Language German
    Size 58 Bl., Ill., graph. Darst.
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Heidelberg, Univ., Diss., 2011
    HBZ-ID HT017121509
    Database Catalogue ZB MED Medicine, Health

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2012 E 236 order for loan Magazin

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article ; Online: Can elderly individuals perform partial weight bearing on their lower limbs? A prospective cohort study using ambulatory real-time biofeedback.

    Merkle, Tobias Peter / Hofmann, Nina / Knop, Christian / Da Silva, Tomas

    Journal of orthopaedic surgery and research

    2023  Volume 18, Issue 1, Page(s) 324

    Abstract: Background: Partial weight bearing in an orthosis and with forearm crutches is a widespread and well-accepted therapeutic principle after an injury of the lower extremity during early rehabilitation. Complying may be challenging to do under these ... ...

    Abstract Background: Partial weight bearing in an orthosis and with forearm crutches is a widespread and well-accepted therapeutic principle after an injury of the lower extremity during early rehabilitation. Complying may be challenging to do under these circumstances, especially for elderly people. This study compares the spatiotemporal parameters and peak loads performed by a group of older participants before and after activating real-time biofeedback (BF) to determine whether they benefit from a biofeedback.
    Methods: Twenty-four healthy subjects between 61 and 80 years learned how to walk using forearm crutches in a lower leg orthosis while performing a weight of 20 kg using a bathroom scale with the aim of loading in a zone between 15 and 30 kg. After that, they completed a course that was on level ground (50 m) and another course on stairs (11 steps). They did a walk without BF first, and then with BF. Each step was given a maximum load, which was determined and statistically checked. In addition, spatiotemporal parameters were collected.
    Results: The classical teaching method with a bathroom scale was ineffective. Only 32.3% of the loads could be adequately carried by a person on level ground in the 15-30 kg target zone. On the stairs, it was 48.2% and 34.3%, respectively. Thus, on level ground, 52.7% of loads exceeded 30 kg. Downstairs it was 46.4%, and upstairs it was 41.6%. Subjects clearly benefit from activated biofeedback. Biofeedback significantly reduced missteps > 30 kg in every course. The loads decreased significantly to 25.0% on level ground, to 23.0% upstairs, and to 24.4% downstairs. At the same time, speed and stride length decreased per course while total time increased.
    Conclusion: Partial weight bearing is more complex and difficult for the elderly. These study results may help better understand 3-point gait in older adults in an outpatient setting. When partial weight bearing is recommended, special follow-up attention must be given for this group. Age-based therapy strategies can be developed and monitored with the assistance of ambulatory biofeedback devices. Trial registration Retrospectively registered, https://www.drks.de/DRKS00031136 .
    MeSH term(s) Aged ; Humans ; Biofeedback, Psychology/methods ; Gait ; Leg ; Partial Weight-Bearing ; Prospective Studies ; Weight-Bearing
    Language English
    Publishing date 2023-04-27
    Publishing country England
    Document type Clinical Study ; Journal Article
    ZDB-ID 2252548-8
    ISSN 1749-799X ; 1749-799X
    ISSN (online) 1749-799X
    ISSN 1749-799X
    DOI 10.1186/s13018-023-03807-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article ; Online: Continuous real-time biofeedback in orthosis improves partial weight bearing on stairs.

    Merkle, Tobias Peter / Hofmann, Nina / Schmidt, Johannes / Dietrich, Thomas / Knop, Christian / Da Silva, Tomas

    Archives of orthopaedic and trauma surgery

    2023  Volume 143, Issue 9, Page(s) 5701–5706

    Abstract: Introduction: Climbing up and down stairs with crutches is a particular challenge. The current study evaluates a commercially available insole orthosis device for weighing an affected limb and for biofeedback training of gait. This study was done on ... ...

    Abstract Introduction: Climbing up and down stairs with crutches is a particular challenge. The current study evaluates a commercially available insole orthosis device for weighing an affected limb and for biofeedback training of gait. This study was done on healthy, asymptomatic individuals before applying to the intended postoperative patient. The outcomes should demonstrate whether a continuous real-time biofeedback (BF) system is more effective on stairs than the current protocol involving a bathroom scale.
    Materials and methods: 59 healthy test subjects received both crutches and an orthosis and learned to apply a 3-point gait with a partial load of 20 kg using a bathroom scale. Thereafter, the participants were asked to complete an up-and-down course, first without (control group) and then with (test group) an audio-visual real-time biofeedback (BF). Compliance was evaluated using an insole pressure measurement system.
    Results: Using the conventional therapy technique, 36.6% of the steps up and 39.1% of the steps down in the control group were loaded with < 20 kg. By activating continuous biofeedback, steps with < 20 kg could be increased significantly to 61.1% upstairs (p < 0.001) and 66.1% downstairs (p < 0.001). All subgroups profited from the BF system, independent of age, gender, side relieved, dominant or non-dominant side.
    Conclusions: Traditional training without biofeedback led to poor performance for partial weight bearing on stairs, even among young and healthy individuals. However, continuous real-time biofeedback clearly improved compliance, indicating its potential to enhance training and support future research in patient populations.
    MeSH term(s) Humans ; Partial Weight-Bearing ; Weight-Bearing ; Biofeedback, Psychology/methods ; Gait ; Orthotic Devices
    Language English
    Publishing date 2023-05-23
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 80407-1
    ISSN 1434-3916 ; 0003-9330 ; 0344-8444
    ISSN (online) 1434-3916
    ISSN 0003-9330 ; 0344-8444
    DOI 10.1007/s00402-023-04878-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Uk I Zs.58: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article: Calcineurin inhibitors in systemic sclerosis - a systematic literature review.

    Hofmann, Nina N / Ambühl, Robert A / Jordan, Suzana / Distler, Oliver

    Therapeutic advances in musculoskeletal disease

    2022  Volume 14, Page(s) 1759720X221092374

    Abstract: Objective: To review treatment effectiveness and adverse events of calcineurin inhibitors (CNIs) such as cyclosporin A (CsA) and tacrolimus in patients with systemic sclerosis (SSc).: Methods: A systematic literature search was performed on PubMed ... ...

    Abstract Objective: To review treatment effectiveness and adverse events of calcineurin inhibitors (CNIs) such as cyclosporin A (CsA) and tacrolimus in patients with systemic sclerosis (SSc).
    Methods: A systematic literature search was performed on PubMed and Web of Science using the predefined keywords 'systemic sclerosis', scleroderma, cyclosporin*, and tacrolimus. Articles were eligible for inclusion, if SSc patients had been treated with CNIs and data on treatment effects were available.
    Results: This systematic literature review identified 37 papers (19 case reports, 15 case series, 2 controlled studies, and 1 retrospective study) including 134 SSc patients treated with CNIs. In 34 of 37 papers, CsA was used. An improvement of skin fibrosis was observed in 77 of 96 (80.2%) patients using a wide variety of outcome measures and dose regimes. Both controlled studies showed significant improvements, one using a historical control group and one using a no-treatment control group. Improvement in pulmonary function tests (PFTs) occurred in 67.9% (19/28) of the patients who had reduced PFTs at baseline. In 58 (43.3%) cases, adverse renal events were reported, of which 7 (5.2%) were severe such as scleroderma renal crisis (SRC), CsA-associated nephropathy, or death by renal insufficiency. Adverse events led to dose reduction, treatment interruption, or withdrawal in 39 of 134 (29.1%).
    Conclusion: In this systematic literature review, signals for potential effectiveness of CsA for skin and pulmonary fibrosis were found, but the evidence level of the identified studies was too low to allow robust conclusions. Randomized controlled double-blind trials are needed to conclude on the effectiveness of CNIs in SSc. Renal toxicity of CNIs was confirmed in this review and needs to be considered in the design of such studies.
    Language English
    Publishing date 2022-05-19
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2516075-8
    ISSN 1759-7218 ; 1759-720X
    ISSN (online) 1759-7218
    ISSN 1759-720X
    DOI 10.1177/1759720X221092374
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Conference proceedings: Begünstigen Biofeedback-Einlegesohlen in der frühen postoperativen Phase nach Sprunggelenksfrakturen die Patientenperformance?

    Hofmann, Nina / Da Silva, Tomas / Knop, Christian / Merkle, Tobias

    2023  , Page(s) AB36–2641

    Event/congress Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU 2023); Berlin; ; Berufsverband für Orthopädie und Unfallchirurgie; 2023
    Keywords Medizin, Gesundheit ; Teilbelastung ; Rehabilitation ; Sprunggelenk ; Fraktur ; Biofeedback
    Publishing date 2023-10-23
    Publisher German Medical Science GMS Publishing House; Düsseldorf
    Document type Conference proceedings
    DOI 10.3205/23dkou154
    Database German Medical Science

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  6. Article: MiR-181a Targets

    Melnik, Svitlana / Hofmann, Nina / Gabler, Jessica / Hecht, Nicole / Richter, Wiltrud

    Frontiers in cell and developmental biology

    2021  Volume 9, Page(s) 747057

    Abstract: Mechanisms of WNT and bone morphogenetic protein (BMP) signaling crosstalk is in the focus of multiple biological studies, and it also has been discovered to play important roles in human mesenchymal stromal cells (MSC) that are of great interest for ... ...

    Abstract Mechanisms of WNT and bone morphogenetic protein (BMP) signaling crosstalk is in the focus of multiple biological studies, and it also has been discovered to play important roles in human mesenchymal stromal cells (MSC) that are of great interest for neocartilage engineering due to their high chondrogenic differentiation potential. However, MSC-derived chondrocytes undergo hypertrophic degeneration that impedes their clinical application for cartilage regeneration. In our previous study, we established that several microRNAs (miRs) are differentially expressed between articular chondrocytes (AC) - and MSC-derived neocartilage, with miR-181a being the most prominent candidate as key microRNA involved in the regulation of a balance between chondral and endochondral differentiation. The aim of this study was the identification of precise mRNA targets and signaling pathways regulated by miR-181a in MSC during chondrogenesis. MiR-181a was upregulated during chondrogenesis of MSC, along with an increase of the hypertrophic phenotype in resulting cartilaginous tissue. By
    Language English
    Publishing date 2021-10-29
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2737824-X
    ISSN 2296-634X
    ISSN 2296-634X
    DOI 10.3389/fcell.2021.747057
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Book ; Online ; Thesis: Analyse des Antisigmafaktors Rsd aus E. coli

    Hofmann, Nina

    Charakterisierung von Bindungspartnern, Einfluss von Rsd auf die Transkription und Regulation des rsd-Gens

    2010  

    Author's details Nina Hofmann
    Language German
    Size Online-Ressource
    Document type Book ; Online ; Thesis
    Thesis / German Habilitation thesis Univ., Diss.--Düsseldorf, 2010
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  8. Book ; Thesis: Medienkonzentration und Meinungsvielfalt

    Hofmann, Nina

    eine Analyse der Funktionsgrenzen der Fusionskontrolle auf dem Pressemarkt

    (Schriftenreihe Institut für Energie- und Wettbewerbsrecht in der Kommunalen Wirtschaft ; 39)

    2010  

    Author's details Nina Hofmann
    Series title Schriftenreihe Institut für Energie- und Wettbewerbsrecht in der Kommunalen Wirtschaft ; 39
    Keywords Pressemarkt ; Meinungsvielfalt ; Pressekonzentration ; Fusionskontrolle ; Mediensektor ; Presseverlag ; Medienwettbewerb ; Pluralismus ; Wirkungsanalyse ; Deutschland
    Language German
    Size 231 S., graph. Darst.
    Edition 1. Aufl.
    Publisher Nomos
    Publishing place Baden-Baden
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Zugl.: Berlin, Humboldt-Univ., Diss., 2009
    ISBN 9783832957278 ; 3832957278
    Database ECONomics Information System

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  9. Book ; Thesis: Medienkonzentration und Meinungsvielfalt

    Hofmann, Nina

    eine Analyse der Funktionsgrenzen der Fusionskontrolle auf dem Pressemarkt

    (Schriftenreihe Institut für Energie- und Wettbewerbsrecht in der Kommunalen Wirtschaft ; 39)

    2010  

    Author's details Nina Hofmann
    Series title Schriftenreihe Institut für Energie- und Wettbewerbsrecht in der Kommunalen Wirtschaft ; 39
    Keywords Pressemarkt ; Meinungsvielfalt ; Pressekonzentration ; Fusionskontrolle ; Mediensektor ; Presseverlag ; Medienwettbewerb ; Pluralismus ; Wirkungsanalyse ; Deutschland ; Europäisches Kartellrecht. Fusionskontrolle ; Kartelle. Presse ; Pressefreiheit
    Language German
    Size 231 S., graph. Darst.
    Edition 1. Aufl.
    Publisher Nomos
    Publishing place Baden-Baden
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Humboldt-Univ., Diss.--Berlin, 2009
    ISBN 9783832957278 ; 3832957278
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  10. Book ; Online ; Thesis: Analyse des Antisigmafaktors Rsd aus E. coli

    Hofmann, Nina [Verfasser]

    Charakterisierung von Bindungspartnern, Einfluss von Rsd auf die Transkription und Regulation des rsd-Gens

    2010  

    Author's details vorgelegt von Nina Hofmann
    Keywords Biowissenschaften, Biologie ; Life Science, Biology
    Subject code sg570
    Language German
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top