Article ; Online: Puzzling phenomenon: adult-onset cancer predisposition and pediatric cancer.
2024
Abstract: Pathogenic variants (PVs) in DNA repair-linked adult-onset cancer predisposition genes, including double heterozygosity, are increasingly identified in pediatric patients with cancer. Their role in childhood cancer, however, remains poorly understood. ... ...
Abstract | Pathogenic variants (PVs) in DNA repair-linked adult-onset cancer predisposition genes, including double heterozygosity, are increasingly identified in pediatric patients with cancer. Their role in childhood cancer, however, remains poorly understood. Integrating comprehensive tumor analysis is integral for understanding the contribution of such PVs in cancer development and personalized cancer care. |
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Language | English |
Publishing date | 2024-03-18 |
Publishing country | United States |
Document type | Journal Article |
ZDB-ID | 2852626-0 |
ISSN | 2405-8025 ; 2405-8033 ; 2405-8033 |
ISSN (online) | 2405-8025 ; 2405-8033 |
ISSN | 2405-8033 |
DOI | 10.1016/j.trecan.2024.02.011 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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