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  1. Article ; Online: Organspende nach irreversiblem Hirnfunktionsausfall : Rechtliche Aspekte und praktisches Vorgehen.

    Englbrecht, Jan Sönke / Holling, Markus

    Die Anaesthesiologie

    2023  Volume 72, Issue 1, Page(s) 67–78

    Abstract: The prerequisites for post-mortem organ donation in Germany include the determination of irreversible loss of brain function, consent to organ donation, and the exclusion of medical contraindications. In addition, mainly because of the shortage of donor ... ...

    Title translation Organ donation after determination of brain death : Legal aspects and practical approach.
    Abstract The prerequisites for post-mortem organ donation in Germany include the determination of irreversible loss of brain function, consent to organ donation, and the exclusion of medical contraindications. In addition, mainly because of the shortage of donor organs in Germany and the sometimes controversial social and media discussions on the topic of organ donation, all physicians involved in the donation process must be familiar with the relevant laws, guidelines, and procedural instructions. This applies especially to those who are to carry out the verification of irreversible brain death. Only then, can they act safely in this challenging situation and serve as competent consultants for all involved.
    MeSH term(s) Humans ; Brain Death/diagnosis ; Informed Consent/legislation & jurisprudence ; Tissue and Organ Harvesting/legislation & jurisprudence ; Tissue and Organ Procurement/legislation & jurisprudence ; Tissue and Organ Procurement/methods ; Germany
    Language German
    Publishing date 2023-01-13
    Publishing country Germany
    Document type English Abstract ; Journal Article
    ISSN 2731-6866
    ISSN (online) 2731-6866
    DOI 10.1007/s00101-022-01241-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Erratum zu: Organspende nach irreversiblem Hirnfunktionsausfall. Rechtliche Aspekte und praktisches Vorgehen.

    Englbrecht, Jan Sönke / Holling, Markus

    Die Anaesthesiologie

    2023  Volume 72, Issue Suppl 1, Page(s) 44

    Title translation Erratum to: Organ donation after determination of brain death: Legal aspects and practical approach.
    Language German
    Publishing date 2023-02-09
    Publishing country Germany
    Document type Published Erratum
    ISSN 2731-6866
    ISSN (online) 2731-6866
    DOI 10.1007/s00101-023-01259-3
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  3. Conference proceedings: Innovative Möglichkeiten mittels Virtual und Augmented Reality in der neurochirurgischen Lehre unter COVID-19-Bedingungen

    Holling, Markus / Friederichs, Hendrik

    2022  , Page(s) P–02–05

    Event/congress Gemeinsame Jahrestagung der Gesellschaft für Medizinische Ausbildung (GMA) und des Arbeitskreises zur Weiterentwicklung der Lehre in der Zahnmedizin (AKWLZ); Halle (Saale); 2022
    Keywords Medizin, Gesundheit
    Publishing date 2022-09-14
    Publisher German Medical Science GMS Publishing House; Düsseldorf
    Document type Conference proceedings
    DOI 10.3205/22gma168
    Database German Medical Science

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  4. Article: How Should We Treat Meningeal Melanocytoma? A Retrospective Analysis of Potential Treatment Strategies.

    Ricchizzi, Sarah / Gallus, Marco / Stummer, Walter / Holling, Markus

    Cancers

    2022  Volume 14, Issue 23

    Abstract: Background: Meningeal melanocytomas (MM) are rare primary melanocytic tumors of the leptomeninges with an incidence of 1:10,000,000. Until now, there has been only sparse information about this tumor entity. Here, we provide a meta-analysis of all cases ...

    Abstract Background: Meningeal melanocytomas (MM) are rare primary melanocytic tumors of the leptomeninges with an incidence of 1:10,000,000. Until now, there has been only sparse information about this tumor entity. Here, we provide a meta-analysis of all cases published in the English language since 1972.
    Methods: A literature review was performed using PubMed and Web of Science. All published cases were evaluated for location, sex, age, therapeutic approach, and outcome. In total, we included 201 patient cases in our meta-analysis.
    Results: The majority of MM was diagnosed more frequently in men between the third and fifth decade of life. Surgery is the preferred therapeutic approach, and total resection is associated with the best outcome. Patients with partial resection or tumor recurrence benefit from adjuvant radiotherapy, whereas chemo- or immunotherapies do not improve the disease course. Malignant transformation was described in 18 patients. Of these, 11 patients developed metastasis.
    Conclusions: We present the first retrospective meta-analysis of all MM cases published in the English language, including an evaluation of different treatment strategies allowing us to suggest a novel treatment guideline highlighting the importance of total resection for recurrence-free survival and characterizing those cases which benefit from adjuvant radiotherapy.
    Language English
    Publishing date 2022-11-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers14235851
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  5. Article: Hirndruck als Traumafolge

    Bohn, Andreas / Brune, Mona / Holling, Markus

    NOTARZT

    2023  Volume 39, Issue 02, Page(s) 65–65

    Language German
    Publishing date 2023-04-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2039417-2
    ISSN 1438-8693 ; 0177-2309
    ISSN (online) 1438-8693
    ISSN 0177-2309
    DOI 10.1055/a-1780-0815
    Database Thieme publisher's database

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  6. Article ; Online: Mixed Reality as a Teaching Tool for Medical Students in Neurosurgery.

    Silvero Isidre, Arturo / Friederichs, Hendrik / Müther, Michael / Gallus, Marco / Stummer, Walter / Holling, Markus

    Medicina (Kaunas, Lithuania)

    2023  Volume 59, Issue 10

    Abstract: Background and ... ...

    Abstract Background and Objectives
    MeSH term(s) Humans ; Augmented Reality ; Neurosurgery ; Students, Medical ; Curriculum ; Educational Measurement
    Language English
    Publishing date 2023-09-26
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2188113-3
    ISSN 1648-9144 ; 1010-660X
    ISSN (online) 1648-9144
    ISSN 1010-660X
    DOI 10.3390/medicina59101720
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  7. Book ; Online ; Thesis: Risikofaktoren für die Entwicklung einer Ventrikulitis im Rahmen der Behandlung einer aneurysmatischen Subarachnoidalblutung

    Stummer, Anna-Katharina [Verfasser] / Holling, Markus [Akademischer Betreuer]

    2022  

    Author's details Anna-Katharina Stummer ; Betreuer: Markus Holling
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Universitäts- und Landesbibliothek Münster
    Publishing place Münster
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  8. Article ; Online: Neurosurgery in Contemporary Medical Dramas: How Grey's Anatomy & Co. May Affect Perception of Neurosurgery in the Media.

    Pilz, Merle / Stummer, Walter / Holling, Markus

    Journal of neurological surgery. Part A, Central European neurosurgery

    2020  Volume 81, Issue 6, Page(s) 495–500

    Abstract: Background:  Neurosurgery is a common topic in contemporary medical dramas. This study aimed to examine depictions of several neurosurgical diseases and techniques as well as the perception of the personality of neurosurgeons in the media, focusing on ... ...

    Abstract Background:  Neurosurgery is a common topic in contemporary medical dramas. This study aimed to examine depictions of several neurosurgical diseases and techniques as well as the perception of the personality of neurosurgeons in the media, focusing on their impact on the physician-patient relationship.
    Methods:  TV series and movies with a main focus on neurosurgeons and/or neurosurgical diseases were identified by consulting the International Movie Database (IMDb).
    Results:  After investigation of many TV series and movies, we identified five main topics: vascular neurosurgery, neuro-oncology, neurointensive care, neurosurgical techniques, and neurosurgeon's personality. The portrayal of neurosurgery in medical drama is characterized to a large extent by sensationalism, a lot of misinformation, and an unfavorable portrayal of neurosurgeons, although it is assumed that expert advice was sought in advance of every production.
    Conclusions:  Considering the popularity of medical dramas and movies dealing with medical topics, we must consider the general public's picture of neurosurgery to be widely influenced by the media.
    MeSH term(s) Adult ; Critical Care/psychology ; Drama ; Female ; Humans ; Male ; Middle Aged ; Neurosurgeons/psychology ; Neurosurgery/trends ; Physician-Patient Relations ; Public Relations ; Television
    Language English
    Publishing date 2020-09-10
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2651663-9
    ISSN 2193-6323 ; 2193-6315
    ISSN (online) 2193-6323
    ISSN 2193-6315
    DOI 10.1055/s-0040-1709169
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Risk factors associated with vasospasm after non-traumatic subarachnoid hemorrhage: a retrospective analysis of 456 patients.

    Joos, Gunther S / Gottschalk, Antje / Ewelt, Christian / Holling, Markus / Stummer, Walter / Englbrecht, Jan S

    Journal of neurosurgical sciences

    2022  Volume 67, Issue 5, Page(s) 576–584

    Abstract: Background: The pathophysiology of vasospasm (VS) after non-traumatic subarachnoid hemorrhage is not completely understood. Several risk factors associated with VS were previously reported, partially with conflicting results. The aim of this study was ... ...

    Abstract Background: The pathophysiology of vasospasm (VS) after non-traumatic subarachnoid hemorrhage is not completely understood. Several risk factors associated with VS were previously reported, partially with conflicting results. The aim of this study was to identify patients at increased risk for VS.
    Methods: Retrospective analysis of data from all patients treated in our institutional intensive care unit (ICU) between 2010 and 2016 after non-traumatic subarachnoid hemorrhage. Possible contributing factors for VS studied were: age, sex, aneurysm-localization, treatment option, ICU-stay, ICU mortality, pre-existing condition, medication history, World Federation of Neurosurgical Societies (WFNS) grading system, modified Fisher scale.
    Results: We obtained data from 456 patients. 184 were male and 272 female patients, respectively. Mean age was 57.7±13.9 and was not different between sexes. In 119 patients, VS was diagnosed after subarachnoid hemorrhage. Incidence of VS was not different between sexes (male: 22.3%, female: 28.7%, P=0.127). Patients with VS were significantly younger (mean age 52.2 vs. 59.7, P<0.001), meanwhile patients aged 36-40 yrs. had the highest incidence of VS. Most VS were found after rupture of middle cerebral artery-aneurysms. Higher incidence of VS was found after aneurysm clipping compared to coiling. VS developed more often in patients with more severe WFNS grade and Fisher scale. In multivariate analysis, age, previous drug abuse and history of anticoagulants were associated with the incidence of VS.
    Conclusions: Younger age, middle cerebral artery-aneurysms, aneurysm clipping, previous drug abuse and history of anticoagulants were associated with a higher incidence of VS after non-traumatic subarachnoid hemorrhage. No gender difference was found.
    MeSH term(s) Humans ; Male ; Female ; Adult ; Middle Aged ; Aged ; Subarachnoid Hemorrhage/epidemiology ; Subarachnoid Hemorrhage/etiology ; Subarachnoid Hemorrhage/surgery ; Retrospective Studies ; Intracranial Aneurysm/surgery ; Risk Factors ; Vasospasm, Intracranial/epidemiology ; Vasospasm, Intracranial/etiology
    Language English
    Publishing date 2022-04-13
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 193139-8
    ISSN 1827-1855 ; 0390-5616 ; 0026-4881
    ISSN (online) 1827-1855
    ISSN 0390-5616 ; 0026-4881
    DOI 10.23736/S0390-5616.22.05497-2
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  10. Article ; Online: Resection of Intramedullary Hemangioblastoma: Timing of Surgery and Its Impact on Neurological Outcome and Quality of Life.

    Schwake, Michael / Ricchizzi, Sarah / Krahwinkel, Sophia / Maragno, Emanuele / Schipmann, Stephanie / Stummer, Walter / Gallus, Marco / Holling, Markus

    Medicina (Kaunas, Lithuania)

    2023  Volume 59, Issue 9

    Abstract: Background and ... ...

    Abstract Background and Objectives
    MeSH term(s) Adult ; Humans ; Hemangioblastoma/surgery ; Quality of Life ; Retrospective Studies ; Cross Infection ; Length of Stay
    Language English
    Publishing date 2023-09-06
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2188113-3
    ISSN 1648-9144 ; 1010-660X
    ISSN (online) 1648-9144
    ISSN 1010-660X
    DOI 10.3390/medicina59091611
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