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  1. Article ; Online: Right ventricular function in severe aortic stenosis assessed by echocardiography and MRI.

    Holmberg, Erica / Tamás, Éva / Nylander, Eva / Engvall, Jan / Granfeldt, Hans

    Clinical physiology and functional imaging

    2023  Volume 44, Issue 3, Page(s) 211–219

    Abstract: Background: The prevalence of aortic valve stenosis (AS) is increasing due to an ageing population. Despite that right ventricular function has prognostic value for postoperative outcome, the right ventricle (RV) is not extensively studied and often not ...

    Abstract Background: The prevalence of aortic valve stenosis (AS) is increasing due to an ageing population. Despite that right ventricular function has prognostic value for postoperative outcome, the right ventricle (RV) is not extensively studied and often not routinely assessed in AS. Our aim was to explore the relation between severe AS and RV function in a surgical aortic valve replacement (SAVR) cohort, comparing two imaging modalities for RV evaluation.
    Methods: Patients with severe AS, underwent cardiovascular magnetic resonance imaging (CMR) and transthoracic echocardiography (TTE) before SAVR. RV dysfunction was defined as one or more of the following: tricuspid annular plane systolic excursion (TAPSE) < 17 mm, RV free wall strain (RVFWS) > -20% by TTE and RV ejection fraction (RVEF) <50% by CMR.
    Results: Sixteen (33%) patients were found to have RV dysfunction. Patients with RV dysfunction showed significantly lower indexed aortic valve area, left ventricular (LV) ejection fraction as well as RV and LV stroke volumes compared to patients with maintained RV function. All patients with reduced RVEF also had changes in TAPSE or RVFWS and a larger number of patients had a reduced longitudinal RV function despite a normal RVEF.
    Conclusion: In a SAVR cohort one-third of the patients had RV dysfunction, defined by RVEF, TAPSE or RVFW strain. Echocardiography detected subtle changes in RV function before RVEF was reduced. It is likely that the more pronounced the AS, the more frequent the occurrence of RV dysfunction.
    MeSH term(s) Humans ; Ventricular Function, Right ; Echocardiography/methods ; Magnetic Resonance Imaging ; Heart ; Stroke Volume ; Aortic Valve Stenosis/diagnostic imaging ; Aortic Valve Stenosis/surgery ; Ventricular Dysfunction, Right/diagnostic imaging ; Ventricular Dysfunction, Right/etiology
    Language English
    Publishing date 2023-11-27
    Publishing country England
    Document type Journal Article
    ZDB-ID 2071203-0
    ISSN 1475-097X ; 1475-0961
    ISSN (online) 1475-097X
    ISSN 1475-0961
    DOI 10.1111/cpf.12867
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: More than 20 years' experience of left ventricular assist device implantation at a non-transplant Centre.

    Holmberg, Erica / Ahn, Henrik / Peterzén, Bengt

    Scandinavian cardiovascular journal : SCJ

    2017  Volume 51, Issue 6, Page(s) 293–298

    Abstract: Objectives: Over recent decades implantable left ventricular assist devices (LVAD) have increased the possibility of improved survival in patients with advanced heart failure who also benefit from a better quality of life. The aim of this retrospective ... ...

    Abstract Objectives: Over recent decades implantable left ventricular assist devices (LVAD) have increased the possibility of improved survival in patients with advanced heart failure who also benefit from a better quality of life. The aim of this retrospective survey was to review the clinical results of LVAD implantation at a low-volume non-transplant centre (Linköping, Sweden) between 1993 and 2016. Our aim was also to assess the mortality and morbidity rates associated with implantation of three LVAD versions at our centre, and to compare our results with those from transplant centres.
    Design: A retrospective cohort study was performed examining the medical records of patients who had a HeartMate
    Results: Our main finding was a survival to heart transplantation rate of 82% among our BTT LVAD patients. The most common adverse event among our patients was infection. A higher frequency of temporary dialysis was seen in the HMII group compared to the HMI group, and the frequency of right ventricular failure was higher in our HMII material.
    Conclusions: Our data suggests that patients requiring long-term LVAD support can safely have their device implanted and cared for at a non-transplant centre.
    Language English
    Publishing date 2017-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 1379906-x
    ISSN 1651-2006 ; 1401-7431
    ISSN (online) 1651-2006
    ISSN 1401-7431
    DOI 10.1080/14017431.2017.1388536
    Database MEDical Literature Analysis and Retrieval System OnLINE

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