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  1. Article ; Online: The ties between food and medicine in early modern Scottish recipe books.

    Holmes, Charlotte

    The journal of the Royal College of Physicians of Edinburgh

    2022  Volume 52, Issue 4, Page(s) 329–335

    Abstract: This article explores the prominent medical theories in Western Europe, paying attention to how these theoretical frameworks changed perceptions of consuming food. It discusses the idea of moderation of food and drink and how it connected to the practice ...

    Abstract This article explores the prominent medical theories in Western Europe, paying attention to how these theoretical frameworks changed perceptions of consuming food. It discusses the idea of moderation of food and drink and how it connected to the practice of Protestantism in the household. Finally, the article explores Scottish domestic papers dating from the seventeenth and eighteenth centuries, focusing on recipe books. Through these sources, this article will highlight the historical ties between food and medicine and how it was understood in the upper-class Scottish households.
    MeSH term(s) Humans ; Europe ; Medicine ; Books ; Scotland
    Language English
    Publishing date 2022-11-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 2866363-9
    ISSN 2042-8189 ; 0953-0932
    ISSN (online) 2042-8189
    ISSN 0953-0932
    DOI 10.1177/14782715221130184
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Common infections and increased risk of developing dementia: compelling evidence for intervention studies.

    Holmes, Clive

    The Lancet. Healthy longevity

    2021  Volume 2, Issue 7, Page(s) e391–e392

    MeSH term(s) Dementia/epidemiology ; Humans
    Language English
    Publishing date 2021-06-18
    Publishing country England
    Document type Journal Article ; Comment
    ISSN 2666-7568
    ISSN (online) 2666-7568
    DOI 10.1016/S2666-7568(21)00147-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Where Medical Statistics Meets Artificial Intelligence. Reply.

    Hunter, David J / Holmes, Christopher

    The New England journal of medicine

    2024  Volume 389, Issue 25, Page(s) 2403–2404

    MeSH term(s) Humans ; Artificial Intelligence ; Public Health
    Language English
    Publishing date 2024-01-01
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMc2312332
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Where Medical Statistics Meets Artificial Intelligence.

    Hunter, David J / Holmes, Christopher

    The New England journal of medicine

    2023  Volume 389, Issue 13, Page(s) 1211–1219

    MeSH term(s) Humans ; Artificial Intelligence/statistics & numerical data ; Public Health/statistics & numerical data ; Medicine/statistics & numerical data
    Language English
    Publishing date 2023-09-27
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMra2212850
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Changes in foveal avascular zone parameters in individuals with prediabetes compared to normoglycemic controls: a systematic review and meta-analysis.

    Kazantzis, Dimitrios / Holmes, Christopher / Wijesingha, Naomi / Sivaprasad, Sobha

    Eye (London, England)

    2024  

    Abstract: To investigate changes in foveal avascular zone parameters in individuals with prediabetes compared to normoglycemic controls. PUBMED, Scopus and Cochrane Library were searched for published articles comparing the foveal avascular zone between ... ...

    Abstract To investigate changes in foveal avascular zone parameters in individuals with prediabetes compared to normoglycemic controls. PUBMED, Scopus and Cochrane Library were searched for published articles comparing the foveal avascular zone between prediabetic individuals and normoglycemic controls as assessed by optical coherence tomography angiography (OCTA). Standardised Mean Difference (SMD) with 95% confidence interval (CI) was computed for the comparison. A total of seven studies were included in our analysis, 6 provided data for the superficial capillary plexus from 345 eyes of individuals with prediabetes and 347 eyes of controls and 4 provided data on the deep capillary plexus from 285 eyes from individuals with prediabetes and 325 eyes of controls. Foveal avascular zone (FAZ) area in the superficial capillary plexus was enlarged in individuals with prediabetes compared to normoglycemic controls (SMD = 0.23, 95% CI = 0.03-0.44, p = 0.03, I
    Language English
    Publishing date 2024-04-08
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 91001-6
    ISSN 1476-5454 ; 0950-222X
    ISSN (online) 1476-5454
    ISSN 0950-222X
    DOI 10.1038/s41433-024-03058-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Conference proceedings ; Online: Multi-well Horner Correction to Bottom Hole Temperatures in depleted oil and gas fields

    Nunn, J. / Saldana, S. / Holmes, C.

    XXVIII General Assembly of the International Union of Geodesy and Geophysics (IUGG)

    2023  

    Abstract: Depleted oil and gas fields contain a wealth of subsurface information that can be repurposed for geothermal, hydrogen, or carbon sequestration applications. The most common temperature measurement in oil and gas fields is the Bottom Hole Temperature ( ... ...

    Abstract Depleted oil and gas fields contain a wealth of subsurface information that can be repurposed for geothermal, hydrogen, or carbon sequestration applications. The most common temperature measurement in oil and gas fields is the Bottom Hole Temperature (BHT). BHTs need to be corrected for disturbances to the thermal field by circulation of cool mud during drilling. The Horner correction is commonly used to correct temperatures back to in-situ conditions. It uses two and preferably three or more temperatures at the same depth measured at different times after mud circulation stops. This information is used to estimate an equilibrium temperature. Unfortunately, very few oil and gas wells have three or more BHT measurements that can be used in the Horner correction. For example, in southwest Weld County of Colorado which is part of the Denver-Julesburg (DJ) basin, there are only 12 wells out of more than 6,000 wells that have been Horner corrected because of the lack of same-depth measurements. In this study, we test whether BHT from nearby wells measured within a few tens of meters of each other in terms of depth can be used to make a Horner correction. We tested horizontal search radii of 400 m and 800 m and vertical search radii of 15 and 50 m. While results need to be screened for obvious errors such as positive Horner slope or unrealistically large correction, this method added hundreds of additional Horner corrected values.
    Subject code 550
    Language English
    Publishing country de
    Document type Conference proceedings ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Stakeholder views on the role of spiritual care in Australian hospitals: An exploratory study.

    Holmes, Cheryl

    Health policy (Amsterdam, Netherlands)

    2018  Volume 122, Issue 4, Page(s) 389–395

    Abstract: Research increasingly demonstrates the contribution of spiritual care to patient experience, wellbeing and health outcomes. Responsiveness to spiritual needs is recognised as a legitimate component of quality health care. Yet there is no consistent ... ...

    Abstract Research increasingly demonstrates the contribution of spiritual care to patient experience, wellbeing and health outcomes. Responsiveness to spiritual needs is recognised as a legitimate component of quality health care. Yet there is no consistent approach to the models and governance of spiritual care across hospitals in Australia. This is consistent with the situation in other developed countries where there is increased attention to identifying best practice models for spiritual care in health. This study explores the views of stakeholders in Australian hospitals to the role of spiritual care in hospitals. A self-completion questionnaire comprising open and closed questions was distributed using a snowball sampling process. Analysis of 477 complete questionnaires indicated high levels of agreement with ten policy statements and six policy objectives. Perceived barriers to spiritual care related to: terminology and roles, education and training, resources, and models of care. Responses identified the issues to inform a national policy agenda including attention to governance and policy structures and clear delineation of roles and scope of practice with aligned education and training models. The inclusion of spiritual care as a significant pathway for the provision of patient-centred care is noted. Further exploration of the contribution of spiritual care to wellbeing, health outcomes and patient experience is invited.
    MeSH term(s) Australia ; Female ; Hospitals ; Humans ; Leadership ; Male ; Patient-Centered Care/methods ; Spirituality ; Surveys and Questionnaires
    Language English
    Publishing date 2018-02-20
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 605805-x
    ISSN 1872-6054 ; 0168-8510
    ISSN (online) 1872-6054
    ISSN 0168-8510
    DOI 10.1016/j.healthpol.2018.02.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Debriefing strategies for interprofessional simulation-a qualitative study.

    Holmes, Catherine / Mellanby, Edward

    Advances in simulation (London, England)

    2022  Volume 7, Issue 1, Page(s) 18

    Abstract: Background: Interprofessional education is becoming more common worldwide. Simulation is one format in which this can effectively take place. The debriefing after the simulation is a critical part of the simulation process as it allows reflection and ... ...

    Abstract Background: Interprofessional education is becoming more common worldwide. Simulation is one format in which this can effectively take place. The debriefing after the simulation is a critical part of the simulation process as it allows reflection and discussion of concepts that arose during the simulation. Debriefing has been noted to be challenging in the literature. Debriefing after interprofessional simulation (IPS) is likely to have even more challenges, many related to the different backgrounds (profession, specialty) of the learners. This study was designed to investigate: 'How do differing learner professions impact on delivery of post simulation debriefing after team based interprofessional simulation-what are the challenges and what strategies can be used to overcome them?'
    Methods: An initial review of the literature was used to identify current understanding and potential themes requiring further exploration. Using the results from the literature as a starting point for topics and questions to be asked, semi-structured interviews were planned, with those who are experienced in debriefing after IPS. The interviews were transcribed then analysed using a framework analysis.
    Results: The literature search resulted in twenty relevant papers. Four dimensions were drawn out from these papers that were directly related to debriefing after IPS: 'the debriefer', 'method of debriefing', 'the learner' and 'psychological safety'. Sixteen interviews occurred between June and August 2020. Ten themes were extracted from the analysis of the transcripts of these interviews: number and specialty of debriefers, credibility, assumptions/preconceptions, nurses vs doctors, method of debriefing, the learner, hierarchy, safe learning environment, inclusion of all learners, and number of debriefers. These themes were fitted in the four dimensions identified in the literature search, and discussed as so.
    Conclusion: Several challenges and strategies were identified during this study. 'It depends' was a common answer received in the interviews suggesting that there is very little advice that can be given that applies to every situation. The main recommendation from this study is the support for an interprofessional group of debriefers in IPS although this does introduce its own challenges. Further research is suggested around the hierarchy found in IPS debriefing and how this translates to and from clinical practice.
    Language English
    Publishing date 2022-06-18
    Publishing country England
    Document type Journal Article
    ISSN 2059-0628
    ISSN (online) 2059-0628
    DOI 10.1186/s41077-022-00214-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Is

    Goldstein, David S / Holmes, Courtney

    Clinical autonomic research : official journal of the Clinical Autonomic Research Society

    2022  Volume 32, Issue 6, Page(s) 445–453

    Abstract: Purpose: 18: Methods: Brain and cardiac : Results: Twelve subjects had severely decreased and eight normal cardiac : Conclusions: ... ...

    Abstract Purpose: 18
    Methods: Brain and cardiac
    Results: Twelve subjects had severely decreased and eight normal cardiac
    Conclusions: 18
    MeSH term(s) Humans ; Parkinson Disease ; Dopamine ; Hypotension, Orthostatic ; Neuroimaging ; Parkinsonian Disorders
    Chemical Substances fluorodopa F 18 (2C598205QX) ; Dopamine (VTD58H1Z2X)
    Language English
    Publishing date 2022-10-08
    Publishing country Germany
    Document type Journal Article ; Research Support, N.I.H., Intramural
    ZDB-ID 1080007-4
    ISSN 1619-1560 ; 0959-9851
    ISSN (online) 1619-1560
    ISSN 0959-9851
    DOI 10.1007/s10286-022-00885-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Review: systemic inflammation and Alzheimer's disease.

    Holmes, C

    Neuropathology and applied neurobiology

    2013  Volume 39, Issue 1, Page(s) 51–68

    Abstract: There is a great deal of evidence suggesting an important role for systemic inflammation in the pathogenesis of Alzheimer's disease. The role of systemic inflammation, and indeed inflammation in general, is still largely considered to be as a contributor ...

    Abstract There is a great deal of evidence suggesting an important role for systemic inflammation in the pathogenesis of Alzheimer's disease. The role of systemic inflammation, and indeed inflammation in general, is still largely considered to be as a contributor to the disease process rather than of aetiological importance although there is emerging evidence to suggest that its role may predate the deposition of amyloid. Therapies aimed at reducing inflammation in individuals with mild cognitive impairment and Alzheimer's disease have been disappointing and have largely focused on the need to ameliorate central inflammation with little attention to the importance of dampening down systemic inflammation. Novel approaches in this area require a greater understanding of the effects of systemic inflammation on the development and progression of Alzheimer's disease and of the communicating pathways between the systemic and central innate immune systems.
    MeSH term(s) Alzheimer Disease/etiology ; Alzheimer Disease/immunology ; Alzheimer Disease/pathology ; Animals ; Humans ; Inflammation/complications ; Inflammation/immunology ; Inflammation/pathology
    Language English
    Publishing date 2013-02
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 80371-6
    ISSN 1365-2990 ; 0305-1846
    ISSN (online) 1365-2990
    ISSN 0305-1846
    DOI 10.1111/j.1365-2990.2012.01307.x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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