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Article ; Online: Motor unit firing rates increase in prepubescent youth following linear periodization resistance exercise training.

Herda, Trent J / Holmes, Elizabeth A / Cleary, Christopher J / Minor, Kelsey T / Thyfault, John P / Shook, Robin P / Herda, Ashley A

European journal of applied physiology

2024

Abstract: Purpose: The purpose was to examine the effects of 8-weeks (3 days/week) of linear periodization resistance exercise training (RET) on neuromuscular function in prepubescent youth.: Methods: Twenty-five healthy prepubescent youth (11 males, 14 ... ...

Abstract	Purpose: The purpose was to examine the effects of 8-weeks (3 days/week) of linear periodization resistance exercise training (RET) on neuromuscular function in prepubescent youth. Methods: Twenty-five healthy prepubescent youth (11 males, 14 females, age = 9.1 ± 0.8 years) completed the RET (n = 17) or served as controls (CON, n = 8). Isometric maximal voluntary contractions (MVCs) and trapezoidal submaximal contractions at 35 and 60% MVC of the right leg extensors were performed with surface electromyography (EMG) recorded from the leg extensors [vastus lateralis (VL), rectus femoris, and vastus medialis] and flexors (biceps femoris and semitendinosus). EMG amplitude of the leg extensors and flexors were calculated during the MVCs. Motor unit (MU) action potential trains were decomposed from the surface EMG of the VL for the 35 and 60% MVCs. MU firing rates and action potential amplitudes were regressed against recruitment threshold with the y-intercepts and slopes calculated for each contraction. Total leg extensor muscle cross-sectional area (CSA) was collected using ultrasound images. ANOVA models were used to examine potential differences. Results: Isometric strength increased post-RET (P = 0.006) with no changes in leg extensor and flexor EMG amplitude. Furthermore, there were no changes in total CSA or the MU action potential amplitude vs. recruitment threshold relationships. However, there were increases in the firing rates of the higher-threshold MUs post-RET as indicated with greater y-intercepts (P = 0.003) from the 60% MVC and less negative slope (P = 0.004) of the firing rates vs. recruitment threshold relationships at 35% MVC. Conclusions: MU adaptations contribute to strength increases following RET in prepubescent youth.
Language	English
Publishing date	2024-04-18
Publishing country	Germany
Document type	Journal Article
ZDB-ID	124793-1
ISSN	1439-6327 ; 1432-1025 ; 0301-5548 ; 1439-6319
ISSN (online)	1439-6327 ; 1432-1025
ISSN	0301-5548 ; 1439-6319
DOI	10.1007/s00421-024-05455-w
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Article: Exploring the role of Northeast Atlantic cod in the Barents Sea food web using a multi‐model approach

Nilsen, Ina / Hansen, Cecilie / Kaplan, Isaac / Holmes, Elizabeth / Langangen, Øystein

Fish and fisheries. 2022 Sept., v. 23, no. 5

2022

Abstract: It is commonly accepted that no ecosystem model is the ‘best’, but rather that ecosystem models should be used in ensembles. This is also the case for the Barents Sea ecosystem, where we have used two different ecosystem models to explore the role of the ...

Abstract	It is commonly accepted that no ecosystem model is the ‘best’, but rather that ecosystem models should be used in ensembles. This is also the case for the Barents Sea ecosystem, where we have used two different ecosystem models to explore the role of the top‐predator Northeast Arctic (NEA) stock of Atlantic cod (Gadus morhua, Gadidae) in the food web. The two models differ in complexity; Gompertz being less complex in terms of food web (7 components) and processes compared to the complex Nordic and Barents Seas Atlantis model (53 components). On the other hand, Gompertz provides thousands of stochastic realizations for each scenario, whereas Atlantis provides only one deterministic simulation. To compare the response to changes in NEA cod on two key prey species, capelin (Mallotus villosus, Osmeridae) and polar cod (Boreogadus saida, Gadidae), we perturbed the historical fishing pressure by ±50% and used the same NEA cod biomass in both models. Even though the links between NEA cod and the prey species are similar in the two models, the results from the study reveal that indirect effects through other food‐web components might be as important as direct predator–prey interactions. Differences in spatial structure and overlap between species also influence the species response to the perturbations. In this study, we focus on the mechanisms that drives the changes in the models, and advise on potential consequences for fisheries management. The two models can complement each other, and the differences between them point to areas where more knowledge is needed.
Keywords	Boreogadus saida ; Gadus morhua ; Mallotus villosus ; biomass ; ecological models ; fish ; food webs ; marine ecosystems ; prey species ; seafoods ; Arctic region ; Barents Sea
Language	English
Dates of publication	2022-09
Size	p. 1083-1098.
Publishing place	John Wiley & Sons, Ltd
Document type	Article
Note	JOURNAL ARTICLE
ZDB-ID	2024569-5
ISSN	1467-2979 ; 1467-2960
ISSN (online)	1467-2979
ISSN	1467-2960
DOI	10.1111/faf.12671
Database	NAL-Catalogue (AGRICOLA)

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Book ; Online: FAQs for NQTs

Holmes, Elizabeth

Practical Advice and Working Solutions for Newly Qualified Teachers

2014

Abstract: This useful reference book offers authoritative yet accessible answers to common questions posed by new and trainee teachers as they face the practical everyday questions that arise from entering the classroom for the first time. Organized into sections ... ...

Abstract	This useful reference book offers authoritative yet accessible answers to common questions posed by new and trainee teachers as they face the practical everyday questions that arise from entering the classroom for the first time. Organized into sections the book covers issues such as:job huntinginductionmanaging workloadrelationship building with pupils and colleaguesdealing with parentsother personal yet work-related issues. The issues covered are ones that have been highlighted through Elizabeth Holmes' work as an online agony aunt for teachers and her column 'Ask Elizabeth' on Eteach.com. B
Language	English
Size	Online-Ressource (185 p)
Publisher	Taylor and Francis
Publishing place	Hoboken
Document type	Book ; Online
Note	Description based upon print version of record
ISBN	9780415367950 ; 0415367956
Database	Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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Book ; Online: What Next After School?

Holmes, Elizabeth

All You Need to Know About Work, Travel and Study

2014

Abstract: What Next After School? has established itself as a key guide for helping students to understand the many options available to them as they approach the end of their school years, including education options (academic as well as vocational training), ... ...

Abstract	What Next After School? has established itself as a key guide for helping students to understand the many options available to them as they approach the end of their school years, including education options (academic as well as vocational training), gap years, the world of work, and practical issues such as finances, debts and insurance. This new 11th edition also includes case studies illustrating how other students have adapted to life after school, as well as detailed information on making the most of the decisions facing all school leavers
Language	English
Size	Online-Ressource (344 p)
Edition	11th ed
Publisher	Kogan Page
Publishing place	London
Document type	Book ; Online
Note	Description based upon print version of record
ISBN	9780749472504 ; 0749472502
Database	Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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Article ; Online: Cell-Free DNA Detects

Long, Dustin R / Holmes, Elizabeth A / Goss, Christopher H / Singh, Pradeep K / Waalkes, Adam / Salipante, Stephen J

American journal of respiratory and critical care medicine

2023 Volume 208, Issue 9, Page(s) 944–947

MeSH term(s)	Humans ; Cystic Fibrosis/complications ; Cystic Fibrosis/drug therapy ; Pseudomonas aeruginosa ; Cell-Free Nucleic Acids ; Pseudomonas Infections/drug therapy ; Anti-Bacterial Agents/therapeutic use ; Lung
Chemical Substances	Cell-Free Nucleic Acids ; Anti-Bacterial Agents
Language	English
Publishing date	2023-08-04
Publishing country	United States
Document type	Letter ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	1180953-x
ISSN	1535-4970 ; 0003-0805 ; 1073-449X
ISSN (online)	1535-4970
ISSN	0003-0805 ; 1073-449X
DOI	10.1164/rccm.202305-0844LE
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Article ; Online: The perspectives of participants with traumatic brain injury on prospective memory rehabilitation incorporating compensatory and metacognitive skills training.

Fleming, Jennifer / Hamilton, Caitlin / Ownsworth, Tamara / Doig, Emmah / Swan, Sarah / Holmes, Elizabeth / Griffin, Janelle / Shum, David H K

Patient education and counseling

2023 Volume 118, Page(s) 108023

Abstract: Objective: Patient feedback is rarely gathered systematically in cognitive rehabilitation research. This study examined the perceptions and experiences of people with traumatic brain injury (TBI) who participated in a trial of a 6-session educational ... ...

Abstract	Objective: Patient feedback is rarely gathered systematically in cognitive rehabilitation research. This study examined the perceptions and experiences of people with traumatic brain injury (TBI) who participated in a trial of a 6-session educational program for the rehabilitation of prospective memory (PM) impairment. Methods: A mixed methods design was used with 47 participants with TBI who completed a compensatory strategy training program (COMP) or COMP plus metacognitive strategy training program (COMP-MST) delivered by an occupational therapist. Data were collected via a participant survey, extracts from progress notes, and audiotaped discussions about learnings from the program during the final session. Results: Participants from both programs were highly satisfied and perceived improvements in everyday PM performance post-intervention. Elements that were highly valued include setting individualised client-centred goals, repetitive training of strategy use, establishing habits and routines, and receiving experiential, verbal, and written feedback.Changes including more therapy sessions were recommended. Conclusions: Both the COMP and COMP-MST programs were perceived as effective by participants with TBI in improving their PM performance in everyday life using compensatory strategies such as assistive technology. Practice implications: Routine collection of patient feedback on cognitive rehabilitation can provide valuable information to support person-centred implementation of clinical practice guidelines.
MeSH term(s)	Humans ; Brain Injuries, Traumatic/psychology ; Brain Injuries, Traumatic/rehabilitation ; Cognition ; Learning ; Memory Disorders ; Memory, Episodic ; Treatment Outcome ; Clinical Trials as Topic
Language	English
Publishing date	2023-10-20
Publishing country	Ireland
Document type	Journal Article
ZDB-ID	605590-4
ISSN	1873-5134 ; 0738-3991
ISSN (online)	1873-5134
ISSN	0738-3991
DOI	10.1016/j.pec.2023.108023
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Book ; Online: The Newly Qualified Teacher's Handbook

Holmes, Elizabeth

2013

Abstract: The Newly Qualified Teachers Handbook is an essential companion for all new teachers. Practical, comprehensive and lively, this invaluable guide covers all aspects of your first crucial months and years, and will set your teaching career off on the right ...

Abstract	The Newly Qualified Teachers Handbook is an essential companion for all new teachers. Practical, comprehensive and lively, this invaluable guide covers all aspects of your first crucial months and years, and will set your teaching career off on the right track. This updated and expanded second edition is the first book to draw on the new Induction Regulations for NQTs for September 2008 onwards. It gives tried and tested advice on everything you need to know, from induction to inspection, from getting your first job to continuing development. New features include a revised first chapter cover
Language	English
Size	Online-Ressource (393 p)
Publisher	Taylor and Francis
Publishing place	Hoboken
Document type	Book ; Online
Note	Description based upon print version of record
ISBN	9780749438579 ; 0749438576
Database	Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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Article ; Online: Contribution of the patient microbiome to surgical site infection and antibiotic prophylaxis failure in spine surgery.

Long, Dustin R / Bryson-Cahn, Chloe / Waalkes, Adam / Holmes, Elizabeth A / Penewit, Kelsi / Tavolaro, Celeste / Bellabarba, Carlo / Zhang, Fangyi / Chan, Jeannie D / Fang, Ferric C / Lynch, John B / Salipante, Stephen J

Science translational medicine

2024 Volume 16, Issue 742, Page(s) eadk8222

Abstract: Despite modern antiseptic techniques, surgical site infection (SSI) remains a leading complication of surgery. However, the origins of SSI and the high rates of antimicrobial resistance observed in these infections are poorly understood. Using ... ...

Abstract	Despite modern antiseptic techniques, surgical site infection (SSI) remains a leading complication of surgery. However, the origins of SSI and the high rates of antimicrobial resistance observed in these infections are poorly understood. Using instrumented spine surgery as a model of clean (class I) skin incision, we prospectively sampled preoperative microbiomes and postoperative SSI isolates in a cohort of 204 patients. Combining multiple forms of genomic analysis, we correlated the identity, anatomic distribution, and antimicrobial resistance profiles of SSI pathogens with those of preoperative strains obtained from the patient skin microbiome. We found that 86% of SSIs, comprising a broad range of bacterial species, originated endogenously from preoperative strains, with no evidence of common source infection among a superset of 1610 patients. Most SSI isolates (59%) were resistant to the prophylactic antibiotic administered during surgery, and their resistance phenotypes correlated with the patient's preoperative resistome (
MeSH term(s)	Humans ; Surgical Wound Infection/prevention & control ; Surgical Wound Infection/drug therapy ; Surgical Wound Infection/microbiology ; Antibiotic Prophylaxis ; Skin ; Anti-Infective Agents ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use
Chemical Substances	Anti-Infective Agents ; Anti-Bacterial Agents
Language	English
Publishing date	2024-04-10
Publishing country	United States
Document type	Journal Article
ZDB-ID	2518854-9
ISSN	1946-6242 ; 1946-6234
ISSN (online)	1946-6242
ISSN	1946-6234
DOI	10.1126/scitranslmed.adk8222
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Book ; Online: What Next After School?

Holmes, Elizabeth

All You Need to Know About Work, Travel and Study

2011

Abstract: What Next After School? offers students, teachers, parents and carers a full assessment of the options facing school-leavers, including education, training, employment and ... ...

Abstract	What Next After School? offers students, teachers, parents and carers a full assessment of the options facing school-leavers, including education, training, employment and travel
Language	English
Size	Online-Ressource (312 p.)
Edition	10th ed
Publisher	Kogan Page
Publishing place	London
Document type	Book ; Online
Note	Description based upon print version of record
ISBN	9780749465322 ; 0749465328
Database	Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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Article: Using modelled prey to predict the distribution of a highly mobile marine mammal

Pendleton, Daniel E / Holmes, Elizabeth E / Redfern, Jessica / Zhang, Jinlun

Diversity & distributions. 2020 Nov., v. 26, no. 11

2020

Abstract: AIM: Species distribution models (SDMs) are a widely used tool to estimate and map habitat suitability for wildlife populations. Most studies that model marine mammal density or distributions use oceanographic proxies for marine mammal prey. However, ... ...

Abstract	AIM: Species distribution models (SDMs) are a widely used tool to estimate and map habitat suitability for wildlife populations. Most studies that model marine mammal density or distributions use oceanographic proxies for marine mammal prey. However, proxies could be a problem for forecasting because the relationships between the proxies and prey may change in a changing climate. We examined the use of model‐derived prey estimates in SDMs using an iconic species, the western Arctic bowhead whale (Balaena mysticetus). LOCATION: Western Beaufort Sea, Alaska, USA. METHODS: We used Biology Ice Ocean Modeling and Assimilation System (BIOMAS) to simulate ocean conditions important to western Arctic bowhead whales, including important prey species. Using both static and dynamic predictors, we applied Maxent and boosted regression tree (BRT) SDMs to predict bowhead whale habitat suitability on an 8‐day timescale. We compared results from models that used bathymetry with those that used only BIOMAS simulated variables. RESULTS: The best model included bathymetry and BIOMAS variables. Inclusion of dynamic variables in SDMs produced predictions that reflected temporal dynamics evident from the survey data. Bathymetry was the most influential variable in models that included that variable. Zooplankton was the most important variable for models that did not include bathymetry. Models with bathymetry performed slightly better than models with only BIOMAS derived variables. MAIN CONCLUSIONS: Bathymetry and modelled zooplankton were the most important predictor variables in bowhead whale distribution models. Our predictions reflected within‐year variability in bowhead whale habitat suitability. Using modelled prey availability, rather than oceanographic proxies, could be important for forecasting species distributions. Predictor variables used in our study were derived from a biophysical ocean model with demonstrated ability to project future ocean conditions. A natural next step is to use output from our biophysical ocean model to understand the effects of Arctic climate change.
Keywords	Balaena mysticetus ; climate change ; geographical distribution ; habitats ; ice ; marine mammals ; models ; prediction ; prey species ; regression analysis ; surveys ; temporal variation ; wildlife ; zooplankton ; Alaska ; Arctic region ; Beaufort Sea
Language	English
Dates of publication	2020-11
Size	p. 1612-1626.
Publishing place	John Wiley & Sons, Ltd
Document type	Article
Note	JOURNAL ARTICLE
ZDB-ID	2020139-4
ISSN	1472-4642 ; 1366-9516
ISSN (online)	1472-4642
ISSN	1366-9516
DOI	10.1111/ddi.13149
Database	NAL-Catalogue (AGRICOLA)

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