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  1. Article ; Online: What must be considered when prescribing hormonal pharmacotherapy for male infertility?

    Holtermann Entwistle, Olivia / Sharma, Aditi / Jayasena, Channa N

    Expert opinion on pharmacotherapy

    2022  Volume 23, Issue 9, Page(s) 1003–1008

    MeSH term(s) Antineoplastic Agents, Hormonal/therapeutic use ; Aromatase Inhibitors/therapeutic use ; Breast Neoplasms/drug therapy ; Humans ; Infertility, Male/drug therapy ; Male ; Selective Estrogen Receptor Modulators/therapeutic use
    Chemical Substances Antineoplastic Agents, Hormonal ; Aromatase Inhibitors ; Selective Estrogen Receptor Modulators
    Language English
    Publishing date 2022-02-28
    Publishing country England
    Document type Editorial
    ZDB-ID 2001535-5
    ISSN 1744-7666 ; 1465-6566
    ISSN (online) 1744-7666
    ISSN 1465-6566
    DOI 10.1080/14656566.2022.2043272
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5130: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Unusual cause of intraoperative haemorrhage: a lesson for patient counselling.

    Alghazawi, Laith Omar Khalaf / Holtermann Entwistle, Olivia / Fehervari, Matyas / Spalding, Duncan

    BMJ case reports

    2022  Volume 15, Issue 6

    Abstract: Hepatocellular carcinoma (HCC) is a well-known malignant neoplasm of the liver associated with spontaneous haemorrhage in 3%-15% of cases. This complication is life threatening and has a mortality rate of 33%-100%. Despite the frequency and severity of ... ...

    Abstract Hepatocellular carcinoma (HCC) is a well-known malignant neoplasm of the liver associated with spontaneous haemorrhage in 3%-15% of cases. This complication is life threatening and has a mortality rate of 33%-100%. Despite the frequency and severity of spontaneous haemorrhage, the importance of patient education about this complication has not been highlighted before. There is currently no information available on the NHS UK website, and no publications have addressed the effect of patient education. We present this case report describing a patient who developed classical symptoms of haemorrhage the day before her elective HCC resection, but was unaware of its importance, and thus did not seek medical attention. She was subsequently found to have a large volume haemoperitoneum, anaemia and a ruptured HCC intraoperatively. This case illustrates the significant importance of counselled regarding the symptoms and risk of spontaneous rupture of HCC to prompt early presentation to medical services.
    MeSH term(s) Blood Loss, Surgical ; Carcinoma, Hepatocellular/pathology ; Carcinoma, Hepatocellular/surgery ; Counseling ; Female ; Hemoperitoneum/etiology ; Hepatectomy ; Humans ; Liver Neoplasms/pathology ; Rupture, Spontaneous/surgery
    Language English
    Publishing date 2022-06-09
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2021-247951
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Prioritising women's and girls' health in disaster settings: Lessons from the COVID-19 pandemic and the overlapping crises affecting Beirut, Lebanon.

    Stevenson, Kerrie / Holtermann-Entwistle, Olivia / Alameddine, Reina / Ghattas, Hala / DeJong, Jocelyn / Singh, Neha / Usta, Jinan

    Global public health

    2022  Volume 17, Issue 5, Page(s) 794–799

    Abstract: The COVID-19 pandemic has placed strain on healthcare systems across the world; however, countries experiencing overlapping crises such as economic or political unrest face immense pressure in ensuring routine healthcare services can continue to operate. ...

    Abstract The COVID-19 pandemic has placed strain on healthcare systems across the world; however, countries experiencing overlapping crises such as economic or political unrest face immense pressure in ensuring routine healthcare services can continue to operate. Despite being less likely suffer severe disease or die from COVID-19, data suggest women have experienced poorer mental health, higher rates of unemployment, and more social isolation during the pandemic. In general, we know women and girls experience multiple forms of disadvantage in disaster contexts including being more likely to become homeless, work as an unpaid carer, and to experience poverty. Research from previous disaster contexts has demonstrated that women's healthcare services tend to be deprioritised in the emergency response, and reports suggest this has been the case during the COVID-19 pandemic. This paper highlights key priorities for safeguarding women's and girls' health in disaster contexts, especially during the COVID-19 pandemic, by drawing on learning from the multiple crises facing Beirut, including responding to the pandemic, economic collapse, and the Beirut Port Explosion in 2020.
    MeSH term(s) COVID-19/epidemiology ; Delivery of Health Care ; Disasters ; Female ; Humans ; Lebanon/epidemiology ; Pandemics
    Language English
    Publishing date 2022-02-21
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2234129-8
    ISSN 1744-1706 ; 1744-1692
    ISSN (online) 1744-1706
    ISSN 1744-1692
    DOI 10.1080/17441692.2022.2043924
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Improvements in Sperm Motility Following Low- or High-Intensity Dietary Interventions in Men With Obesity.

    Sharma, Aditi / Papanikolaou, Nikoleta / Abou Sherif, Sara / Dimakopolou, Anastasia / Thaventhiran, Thilipan / Go, Cara / Holtermann Entwistle, Olivia / Brown, Adrian / Luo, Rong / Jha, Rama / Prakash, Anavi / Khalifa, Dalia / Lewis, Hannah / Ramaraju, Sruthi / Leeds, Anthony R / Chahal, Harvinder / Purkayastha, Sanjay / Henkel, Ralf / Minhas, Sukhbinder /
    Frost, Gary / Dhillo, Waljit S / Jayasena, Channa N

    The Journal of clinical endocrinology and metabolism

    2023  Volume 109, Issue 2, Page(s) 449–460

    Abstract: Introduction: Obesity increases risks of male infertility, but bariatric surgery does not improve semen quality. Recent uncontrolled studies suggest that a low-energy diet (LED) improves semen quality. Further evaluation within a randomized, controlled ... ...

    Abstract Introduction: Obesity increases risks of male infertility, but bariatric surgery does not improve semen quality. Recent uncontrolled studies suggest that a low-energy diet (LED) improves semen quality. Further evaluation within a randomized, controlled setting is warranted.
    Methods: Men with obesity (18-60 years) with normal sperm concentration (normal count) (n = 24) or oligozoospermia (n = 43) were randomized 1:1 to either 800 kcal/day LED for 16 weeks or control, brief dietary intervention (BDI) with 16 weeks' observation. Semen parameters were compared at baseline and 16 weeks.
    Results: Mean age of men with normal count was 39.4 ± 6.4 in BDI and 40.2 ± 9.6 years in the LED group. Mean age of men with oligozoospermia was 39.5 ± 7.5 in BDI and 37.7 ± 6.6 years in the LED group. LED caused more weight loss than BDI in men with normal count (14.4 vs 6.3 kg; P < .001) and men with oligozoospermia (17.6 vs 1.8 kg; P < .001). Compared with baseline, in men with normal count total motility (TM) increased 48 ± 17% to 60 ± 10% (P < .05) after LED, and 52 ± 8% to 61 ± 6% (P < .0001) after BDI; progressive motility (PM) increased 41 ± 16% to 53 ± 10% (P < .05) after LED, and 45 ± 8% to 54 ± 65% (P < .001) after BDI. In men with oligozoospermia compared with baseline, TM increased 35% [26] to 52% [16] (P < .05) after LED, and 43% [28] to 50% [23] (P = .0587) after BDI; PM increased 29% [23] to 46% [18] (P < .05) after LED, and 33% [25] to 44% [25] (P < .05) after BDI. No differences in postintervention TM or PM were observed between LED and BDI groups in men with normal count or oligozoospermia.
    Conclusion: LED or BDI may be sufficient to improve sperm motility in men with obesity. The effects of paternal dietary intervention on fertility outcomes requires investigation.
    MeSH term(s) Male ; Humans ; Semen Analysis ; Sperm Motility ; Oligospermia ; Semen ; Sperm Count ; Infertility, Male/etiology ; Spermatozoa ; Obesity/complications ; Obesity/surgery
    Language English
    Publishing date 2023-09-01
    Publishing country United States
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 3029-6
    ISSN 1945-7197 ; 0021-972X
    ISSN (online) 1945-7197
    ISSN 0021-972X
    DOI 10.1210/clinem/dgad523
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uh III Zs.134: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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