LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Back to previous search Search history
Advanced search

Your last searches

  1. AU="Homa Rasoolijazi"
  2. AU="Guimón, José"

Search results

Result 1 - 2 of total 2

Search options

  1. Article ; Online: A Review on Brain Evolution and Development

    Fatemeh Tahmasebi / Homa Rasoolijazi / Shirin Barati

    Journal of Research in Applied and Basic Medical Sciences, Vol 8, Iss 3, Pp 137-

    2022  Volume 144

    Abstract: Development of human brain is the essential process in the prenatal period of human growth. The total surface of human brain area is 1820 cm2, and the average cortical thickness is 2.7 mm. We reviewed and referred to several articles in this field. ... ...

    Abstract Development of human brain is the essential process in the prenatal period of human growth. The total surface of human brain area is 1820 cm2, and the average cortical thickness is 2.7 mm. We reviewed and referred to several articles in this field. Comparative studies of the primate's brain show that there are general architectural basis governing the brain growth and evolutionary development. In this study, it is discussed about the human brain development with highlighting on the main mechanisms in the embryonic stage and early postnatal life as well as the general architectural values in brain evolution from primates to now. It is suggested that neurodevelopment involves some genetic bases in the neural stem cells proliferation, cortical neurons migration, cerebral cortex folding, synaptogenesis, gliogenesis, and myelination of neural fibers.
    Keywords neurodevelopment ; brain evolution ; prenatal stage ; primate ; Medicine ; R
    Language English
    Publishing date 2022-07-01T00:00:00Z
    Publisher Urmia University of Medical Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  2. Article ; Online: Neuroprotective Effects of Carnosic Acid in an Experimental Model of Alzheimer’s Disease in Rats

    Mohammad Taghi Joghataie / Homa Rasoolijazi / Nahid Azad / Sara Soleimani

    Cell Journal, Vol 13, Iss 1, Pp 39-

    2011  Volume 44

    Abstract: Objective: Alzheimer’s disease is the most common type of neurodegenerative disorder.It has been suggested that oxidative stress can be one of the pathological mechanisms ofthis disease. Carnosic acid (CA) is an effective antioxidant substance and recent ...

    Abstract Objective: Alzheimer’s disease is the most common type of neurodegenerative disorder.It has been suggested that oxidative stress can be one of the pathological mechanisms ofthis disease. Carnosic acid (CA) is an effective antioxidant substance and recent studieshave shown that its electrophilic compounds play a role in reversing oxidative stress. Thuswe tried to find out whether CA administration protects hippocampal neurons, preventingneurodegeneration in rats.Materials and Methods: Animals were divided into four groups: Sham-operated (sham),CA-pretreated sham-operated (sham+CA), untreated lesion (lesion) and CA-pretreatedlesion (lesion+CA). Animals in all groups received vehicle or vehicle plus CA (CA: 10mg/kg) intra-peritoneally one hour before surgery, again the same solution injected 3-4hours after surgery (CA: 3 mg/kg) and repeated each afternoon for 12 days. A lesionwas made by bilateral intra-hippocampal injection of 4 μl of beta amyloid protein (1.5nmol/μl) or vehicle in each side. 14 days after surgery, the brains were extracted forhistochemical studies. Data was expressed as mean ± SEM and analyzed using SPSSstatistical software.Results: Results showed that pretreatment with carnosic acid can reduce cellular deathin the cornu ammonis 1 (CA1) region of the hippocampus in the lesion+CA group, as comparedwith the lesion group.Conclusion: Carnosic acid may be useful in protecting against beta amyloid-induced neurodegenerationin the hippocampus.
    Keywords Carnosic Acid ; Alzheimer’s Disease ; Hippocampus ; Medicine ; R ; Science ; Q
    Subject code 630
    Language English
    Publishing date 2011-01-01T00:00:00Z
    Publisher Royan Institute (ACECR), Tehran
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top