LIVIVO - Das Suchportal für Lebenswissenschaften

switch to English language
Zurück zur letzten Suche Suchhistorie
Erweiterte Suche

Ihre letzten Suchen

  1. AU="Hong, Fan"
  2. AU="Zhao, Shiteng"
  3. AU="Zimmermann, Lisa"
  4. AU="Malone, Daniel C"
  5. AU="Kuo, Sheree"
  6. AU="Leonard, Warren J"
  7. AU=Hawthorne Dawn M
  8. AU=Zein Ahmad Fariz Malvi Zamzam
  9. AU="Delgado, Fernanda"
  10. AU="André Scherag"
  11. AU="Simring, Steven"
  12. AU="Gowdy, John M."
  13. AU="Yeldandi, Anjana"
  14. AU="Mierdel, Katrin"
  15. AU="Karaaslan, Ayse"
  16. AU="Fuchs, Ch"
  17. AU="Toro, Diana"
  18. AU="Lindner, Robert"
  19. AU="Meshkat, Shakila"
  20. AU="Geist, Felix"
  21. AU="Xiong, Yinyi"
  22. AU="Larciprete, R"
  23. AU="Camila Mugnai Vieira"
  24. AU="Michael Sjöström"
  25. AU="Bouchau, Robin"
  26. AU="Shahabi Rabori, Venus"
  27. AU="Jeronimo, Matthew"
  28. AU="Misra, Maitreyi"
  29. AU="Liu, Xuping"
  30. AU="Corinna Lüneburg"
  31. AU="Clement, Lionel C"
  32. AU="Parkhill, Julian"
  33. AU="Wiita, Arun P"
  34. AU=Lubrano Riccardo
  35. AU=Biggs Andrew
  36. AU="Lian, Kejian"
  37. AU="Almutairi, Abdulrahman"
  38. AU="Cosculluela-Pueyo, Rafaél"
  39. AU="Gehrs, Teresa"
  40. AU="Munir, Atif"
  41. AU="Ou, Ya-Nan"
  42. AU=Brown James E AU=Brown James E
  43. AU="Wang, Zhongmin"
  44. AU="Lemieux, Audrée"
  45. AU="Abdelhameed, Mohamed F"
  46. AU="Schaible, Lonnie M"
  47. AU="Yazie, Taklo Simeneh Yazie"
  48. AU="Jude Orumuah Agbugui"
  49. AU="Kruse, Robert L"
  50. AU="Shyama Nandakumar"
  51. AU="Gelb, M"
  52. AU="Gasparini, L"
  53. AU="Ulvila, J"
  54. AU="Länsimies, Helena"

Suchergebnis

Treffer 1 - 10 von insgesamt 295

Suchoptionen

  1. Artikel ; Online: Identification of systemically important banks in China based on Merton-Shapley model and a comparison between different indicators

    Hong Fan / Yating Zhao

    Heliyon, Vol 8, Iss 12, Pp e12238- (2022)

    2022  

    Abstract: Accurately measuring systemic risk in the banking industry and identifying systemically important banks are significant parts of macro-prudential supervision. However, there is a lack of research on measuring systemic risk and identifying important banks ...

    Abstract Accurately measuring systemic risk in the banking industry and identifying systemically important banks are significant parts of macro-prudential supervision. However, there is a lack of research on measuring systemic risk and identifying important banks under the same framework. And there are relatively few studies comparing different indicators of systemically important banks in the context of China's banking industry. Therefore, this paper first constructs a new Merton model to measure the dynamically evolving systemic risk of China's banking system. Then combine the Merton model with the Shapley value to construct the Merton-Shapley framework, and propose a new indicator MShv to identify systemically important banks. At last, use the data of China's banking industry from 2006 to 2019 to conduct an empirical study. The research results show that the systemic risk in China peaked in 2008 and 2015 near the stock market crash, after 2008 the risk appeared a fluctuating decline. And it is found that MShv can accurately identify important banks and simultaneously is conducive to policy implementation. By a comparison between MShv and other systemic risk contribution indicators such as ΔCoVaR, MES, and SRISK, we find that there are many differences for different indicators in the applicability of identifying systemically important banks, the information reflected, and so on. Regulators can consider using several indicators synthetically to supervise banks during different risk periods, in order to maintain the stability of the financial system.
    Schlagwörter Systemically important banks ; Merton model ; Shapley value ; Indicator comparison ; Macro-prudential supervision ; Science (General) ; Q1-390 ; Social sciences (General) ; H1-99
    Thema/Rubrik (Code) 332
    Sprache Englisch
    Erscheinungsdatum 2022-12-01T00:00:00Z
    Verlag Elsevier
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

    Volltext online

    Zusatzmaterialien

    Kategorien

    Fernleihe an ZB MED

    Sie können sich den gewünschten Titel als lokale Nutzerin oder lokaler Nutzer von ZB MED direkt an den Standort Köln schicken lassen.

  3. Artikel ; Online: Research on Financial Systemic Risk in ASEAN Region

    Hong Fan / Renyun Liu

    Entropy, Vol 23, Iss 1131, p

    2021  Band 1131

    Abstract: The research of financial systemic risk is an important issue, however the research on the financial systemic risk in ASEAN region lacks. This paper uses the minimum density method to calculate the interbank network of ASEAN countries and uses the node ... ...

    Abstract The research of financial systemic risk is an important issue, however the research on the financial systemic risk in ASEAN region lacks. This paper uses the minimum density method to calculate the interbank network of ASEAN countries and uses the node centrality to judge the systemically important banks of various countries. Then the DebtRank algorithm is constructed to calculate the systemic risk value based on the interbank network. By comparing the systemic risk values obtained through the initial impact on the system important banks and non-important banks, we find that the systemic risk tends to reach the peak in the case of the initial impact on the system important banks. Furthermore, it is found that countries with high intermediary centrality and closeness centrality have higher systemic risk. It suggests that the regulatory authorities should implement legal supervision, strict supervision, and comprehensive supervision for key risk areas and weak links.
    Schlagwörter systemic risk ; node centricity ; ASEAN region ; minimum density method ; interbank network ; Science ; Q ; Astrophysics ; QB460-466 ; Physics ; QC1-999
    Thema/Rubrik (Code) 332
    Sprache Englisch
    Erscheinungsdatum 2021-08-01T00:00:00Z
    Verlag MDPI AG
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

    Volltext online

    Zusatzmaterialien

    Kategorien

    Fernleihe an ZB MED

    Sie können sich den gewünschten Titel als lokale Nutzerin oder lokaler Nutzer von ZB MED direkt an den Standort Köln schicken lassen.

  4. Artikel: Iterative GMM for partially linear single-index models with partly endogenous regressors

    Zhang, Hong-Fan

    Computational statistics & data analysis. 2021 Apr., v. 156

    2021  

    Abstract: In this paper, we consider the estimation method for the partially linear single-index model with endogenous regressors in the linear part. The Generalized Method of Moments (GMM) using instrumental variables is applied to cope with the problem that the ... ...

    Abstract In this paper, we consider the estimation method for the partially linear single-index model with endogenous regressors in the linear part. The Generalized Method of Moments (GMM) using instrumental variables is applied to cope with the problem that the parameter estimators may be inconsistent due to endogeneity. The GMM estimation is based on an iterative procedure, which has generalized the well known Minimum Average conditional Variance Estimation (MAVE) method, in the sense that in each iteration the estimates of the nonparametric components and the parameter vectors are obtained from the generalized moments equation instead of the least squares optimization. A specific algorithm to implement the estimation procedure concerning the choice of the instruments is provided. Asymptotic properties of the estimators are also established. Simulated experiments show that the proposed estimation method performs well in finite samples. Application to the National Longitudinal Survey of Young Men data illustrates the proposed model and method in analyzing the returns to schooling.
    Schlagwörter algorithms ; data analysis ; equations ; estimation ; least squares ; longitudinal studies ; men ; models ; paper ; sampling ; variance
    Sprache Englisch
    Erscheinungsverlauf 2021-04
    Erscheinungsort Elsevier B.V.
    Dokumenttyp Artikel
    Anmerkung NAL-light
    ZDB-ID 1478763-5
    ISSN 0167-9473
    ISSN 0167-9473
    DOI 10.1016/j.csda.2020.107145
    Datenquelle NAL Katalog (AGRICOLA)

    Volltext online

    Zusatzmaterialien

    Kategorien

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

  5. Artikel ; Online: Co-overexpression of BRD4 and CDK7 promotes cell proliferation and predicts poor prognosis in HCC

    Xinxiu Li / Chuqian Zheng / Yue Liu / Hui Sun / Yanyan Qian / Hong Fan

    Heliyon, Vol 10, Iss 2, Pp e24389- (2024)

    2024  

    Abstract: Aberrant expression of critical components of the trans-acting super-enhancers (SE) complex contributes to the continuous and robust transcription of oncogenes in human cancers. Small-molecule inhibitors targeting core-transcriptional components such as ... ...

    Abstract Aberrant expression of critical components of the trans-acting super-enhancers (SE) complex contributes to the continuous and robust transcription of oncogenes in human cancers. Small-molecule inhibitors targeting core-transcriptional components such as transcriptional bromodomain protein 4 (BRD4) and cyclin-dependent kinase 7 (CDK7) have been developed and are currently undergoing preclinical and clinical testing in several malignant cancers. By analysis of TCGA data and clinical specimens, we demonstrated that BRD4 and CDK7 were frequently overexpressed in human HCCs and were associated with the poor prognosis. Shorter survival and poorly differentiated histology were linked to high BRD4 or CDK7 expression levels. Interestingly, co-overexpression of BRD4 and CDK7 was a more unfavorable prognostic factor in HCC. Treatment with JQ1 or THZ1 alone exhibited an inhibitory impact on the proliferation of HCC cells, while JQ1 synergized with THZ1 showed a more pronounced suppression. Concurrently, a combined JQ1 and THZ1 treatment abolished the transcription of oncogenes ETV4, MYC, NFE2L2. Our study suggested that BRD4 and CDK7 coupled can be a valuable biomarker in HCC diagnosis and the combination of JQ1 and THZ1 can be a promising therapeutic treatment against HCC.
    Schlagwörter BRD4 ; CDK7 ; Combined inhibition ; Cell proliferation ; Science (General) ; Q1-390 ; Social sciences (General) ; H1-99
    Sprache Englisch
    Erscheinungsdatum 2024-01-01T00:00:00Z
    Verlag Elsevier
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

    Volltext online

    Zusatzmaterialien

    Kategorien

    Fernleihe an ZB MED

    Sie können sich den gewünschten Titel als lokale Nutzerin oder lokaler Nutzer von ZB MED direkt an den Standort Köln schicken lassen.

  6. Artikel ; Online: Aligning Superconducting Transition-Edge Sensors by Reflected Wave Intensity Measurement.

    Ma, Pei-Sa / Zhang, Hong-Fan / Zhou, Xingxiang

    Sensors (Basel, Switzerland)

    2023  Band 23, Heft 7

    Abstract: It is critical to accurately align a quantum photon detector such as a superconducting transition-edge sensor (TES) to an optical fiber in order to optimize its detection efficiency. Conventionally, such alignment requires advanced infrared imaging ... ...

    Abstract It is critical to accurately align a quantum photon detector such as a superconducting transition-edge sensor (TES) to an optical fiber in order to optimize its detection efficiency. Conventionally, such alignment requires advanced infrared imaging equipment or sophisticated microfabrication. We introduce a novel technique based on the simple idea of reflected wave intensity measurement which allows to determine the boundary of the sensor and align it accurately with the fiber. By routing a light wave through an optical fiber for normal incidence on the surface of the sensor chip, and separating the reflected wave coupled back into the fiber from the input signal with a circulator, we can observe the variation in the reflected wave intensity when the beam spot of the fiber crosses the boundary between the sensor and substrate that have different reflectivity, and adjust the position of the fiber such that its output falls on the sensor. We evaluate quantitatively the precision of our alignment method, as well as the conditions that must be met to avoid photon loss caused by light beam divergence. After demonstrating the working principle of our scheme and verifying the alignment result experimentally, we employ it for efficient input signal coupling to a TES device, which is used for photon-number-resolving measurement to showcase the successful application of our alignment method in practice. Relying on only ordinary and widely used optical elements that are easy to operate and low in cost, our solution is much less demanding than conventional methods. Dramatically easier to implement and not restricted by the detection mechanism of the sensor, it is accessible to a much broader community.
    Sprache Englisch
    Erscheinungsdatum 2023-03-27
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s23073495
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

  7. Artikel ; Online: Model to Predict Recurrent Hepatocellular Carcinoma after Resection: Impact of α-Fetoprotein in Patients with Cirrhosis: In Reply to Toro and colleagues.

    Ding, Hong-Fan / Zhang, Xu-Feng / Pawlik, Timothy M

    Journal of the American College of Surgeons

    2023  Band 237, Heft 3, Seite(n) 582

    Mesh-Begriff(e) Humans ; Carcinoma, Hepatocellular/surgery ; Carcinoma, Hepatocellular/pathology ; Liver Neoplasms/surgery ; Liver Neoplasms/pathology ; alpha-Fetoproteins ; Liver Cirrhosis/complications ; Liver Cirrhosis/surgery
    Chemische Substanzen alpha-Fetoproteins
    Sprache Englisch
    Erscheinungsdatum 2023-05-17
    Erscheinungsland United States
    Dokumenttyp Letter ; Comment
    ZDB-ID 1181115-8
    ISSN 1879-1190 ; 1072-7515
    ISSN (online) 1879-1190
    ISSN 1072-7515
    DOI 10.1097/XCS.0000000000000764
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

    Verfügbar in ZB MED Köln/Königswinter

    Uk I Zs.61: Hefte anzeigen Standort:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

  8. Artikel ; Online: Urban configuration and PM2.5 concentrations

    Luyao Wang / Dongxiao Niu / Hong Fan / Xiaoyu Long

    Environment International, Vol 161, Iss , Pp 107129- (2022)

    Evidence from 330 Chinese cities

    2022  

    Abstract: Preventing high concentrations of fine particulate (PM2.5) to realize the goal of sustainable development is becoming a challenge for rapidly urbanized cities. Increasing vehicle emission due to inefficient urban form is thought to be the main cause of ... ...

    Abstract Preventing high concentrations of fine particulate (PM2.5) to realize the goal of sustainable development is becoming a challenge for rapidly urbanized cities. Increasing vehicle emission due to inefficient urban form is thought to be the main cause of traffic congestion and increased PM2.5 concentrations. Previous efforts attributing PM2.5 concentrations to urban forms are yet to reach consistent conclusions on practical environmental protection strategies. In this study, we considered urban compositions and their spatial configuration to propose a new measurement—urban configuration—and document the effects of urban configuration on PM2.5 concentrations. Using 330 Chinese cities as our sample, we found that the areas of two types of urban facilities, namely, residence and industry, are positively related to PM2.5 concentrations, and the area of public service facilities is negatively related to PM2.5 concentrations. Regarding the spatial configuration of different urban compositions, we documented that residence–industry accessibility is a key factor of PM2.5 concentrations and plays a more important role than the residence–commerce accessibility. We also compared the influence of two accessibility indices (distance- and gravity-based accessibilities) and further found that the effect of reducing the residence–industry distance is more remarkable than the effect of increasing residential or industrial area on reducing PM2.5 concentrations. Our results indicate that the key to reaching sustainable urban expansion is to synchronize urban constructions with spatial configuration optimization. For Chinese cities, a 7.52% increase in residence area requires at least 1% decrease in the average residence–industry distance to eliminate the incremental effects of newly constructed residential region on PM2.5 concentrations. This study casts new light on the relationship between urban configuration and PM2.5 concentration and provides decision makers practical and realistic approaches in realizing sustainable ...
    Schlagwörter Urban configuration ; PM2.5 concentration ; Urban form ; Spatial configuration ; Residence–industry accessibility ; Sustainable development ; Environmental sciences ; GE1-350
    Thema/Rubrik (Code) 710
    Sprache Englisch
    Erscheinungsdatum 2022-03-01T00:00:00Z
    Verlag Elsevier
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

    Volltext online

    Zusatzmaterialien

    Kategorien

    Fernleihe an ZB MED

    Sie können sich den gewünschten Titel als lokale Nutzerin oder lokaler Nutzer von ZB MED direkt an den Standort Köln schicken lassen.

  9. Artikel ; Online: The Effect of Shadow Banking on the Systemic Risk in a Dynamic Complex Interbank Network System

    Hong Fan / Hongjie Pan

    Complexity, Vol

    2020  Band 2020

    Abstract: After the financial crisis triggered by the subprime mortgage crisis in the United States in 2008, many scholars believed that the unstable transmission of shadow banking business in the banking system is the main factor causing financial turmoil. This ... ...

    Abstract After the financial crisis triggered by the subprime mortgage crisis in the United States in 2008, many scholars believed that the unstable transmission of shadow banking business in the banking system is the main factor causing financial turmoil. This paper proposes a dynamic complex interbank network system model with shadow banking in which the dynamic complex interbank network system differs from the traditional banking network and is formed by the interrelated business between shadow banks and commercial banks to explore the effect of shadow banking on the systemic risk. The results show that the existence of shadow banking will increase the systemic risk, accelerate the speed of bankruptcy of banks, reduce the survival ratio of banks, and increase the strength of central bank assistance. The smaller the number of shadow banks in the system, the higher the degree of credit connection among commercial banks and the smaller the systemic risk.
    Schlagwörter Electronic computers. Computer science ; QA75.5-76.95
    Thema/Rubrik (Code) 332
    Sprache Englisch
    Erscheinungsdatum 2020-01-01T00:00:00Z
    Verlag Hindawi-Wiley
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

    Volltext online

    Zusatzmaterialien

    Kategorien

    Fernleihe an ZB MED

    Sie können sich den gewünschten Titel als lokale Nutzerin oder lokaler Nutzer von ZB MED direkt an den Standort Köln schicken lassen.

  10. Artikel ; Online: Perceptions of Chinese hospital leaders on joint commission international accreditation

    HongFan Zhang / Siou-Tang Huang / Mark J. Bittle / Lilly Engineer / Herng-Chia Chiu

    Frontiers in Public Health, Vol

    a qualitative study

    2023  Band 11

    Abstract: BackgroundJoint Commission International (JCI) accreditation plays a significant role in improving the quality of care and patient safety worldwide. Hospital leadership is critical in making international accreditation happen with successful ... ...

    Abstract BackgroundJoint Commission International (JCI) accreditation plays a significant role in improving the quality of care and patient safety worldwide. Hospital leadership is critical in making international accreditation happen with successful implementation. Little is known about how Chinese hospital leaders experienced and perceived the impact of JCI accreditation. This paper is the first study to explore the perceptions of hospital leaders toward JCI accreditation in China.MethodsQualitative semi-structured interviews were used to explore the perceptions of the chief operating officers, the chief medical officers, and the chief quality officers in five JCI-accredited hospitals in China. Thematic analysis was used to analyze the interview transcripts and identify the main themes.ResultsFifteen hospital leaders participated in the interviews. Three themes emerged from the analysis, namely the motivations, challenges, and benefits related to pursuing and implementing JCI accreditation. The qualitative study found that eight factors influenced hospital leadership to pursue JCI accreditation, five challenges were identified with implementing JCI standards, and eight benefits emerged from the leadership perspective.ConclusionPursuing JCI accreditation is a discretionary decision by the hospital leadership. Participants were motivated by prevalent perceptions that JCI requirements would be used as a management tool to improve the quality of care and patient safety in their hospitals. These same organizational leaders identified challenges associated with implementing and sustaining JCI accreditation. The significant challenges were a clear understanding of the foreign accreditation standards, making staff actively participate in JCI processes, and changing staff behaviors accordingly. The top 5 perceived benefits to JCI accreditation from the leaders’ perspective were improved leadership and hospital safety, improvements in the care processes, and the quality of care and the learning culture improved. Other perceived ...
    Schlagwörter joint commission international ; accreditation ; leadership ; Chinese hospital ; qualitative study ; Public aspects of medicine ; RA1-1270
    Thema/Rubrik (Code) 360
    Sprache Englisch
    Erscheinungsdatum 2023-10-01T00:00:00Z
    Verlag Frontiers Media S.A.
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

    Volltext online

    Zusatzmaterialien

    Kategorien

    Fernleihe an ZB MED

    Sie können sich den gewünschten Titel als lokale Nutzerin oder lokaler Nutzer von ZB MED direkt an den Standort Köln schicken lassen.

Zum Seitenanfang