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  1. Book ; Online ; E-Book: The Mekong River Basin

    Nguyen, Hong Quan / Apel, Heiko / Le, Quang Bao / Sridhar, Venkataramana

    Ecohydrological Complexity from Catchment to Coast

    (Issn Series)

    2024  

    Series title Issn Series
    Subject code 577.60959
    Language English
    Size 1 online resource (674 pages)
    Edition 1st ed.
    Publisher Elsevier
    Publishing place San Diego
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 0-323-91450-0 ; 0-323-90814-4 ; 978-0-323-91450-5 ; 978-0-323-90814-6
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Rh-catalyzed asymmetric hydrogenation of α- and β-enamido phosphonates: highly enantioselective access to amino phosphonic acids.

    Du, Hong-Quan

    Organic & biomolecular chemistry

    2022  Volume 20, Issue 45, Page(s) 8843–8848

    Abstract: Catalytic asymmetric hydrogenation of α- and β-enamido phosphonates was developed using a complex ... ...

    Abstract Catalytic asymmetric hydrogenation of α- and β-enamido phosphonates was developed using a complex formed
    MeSH term(s) Organophosphonates/chemistry ; Hydrogenation ; Rhodium/chemistry ; Stereoisomerism ; Amino Acids ; Amines ; Catalysis
    Chemical Substances Organophosphonates ; Rhodium (DMK383DSAC) ; Amino Acids ; Amines
    Language English
    Publishing date 2022-11-23
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2097583-1
    ISSN 1477-0539 ; 1477-0520
    ISSN (online) 1477-0539
    ISSN 1477-0520
    DOI 10.1039/d2ob01419j
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Low temperature synthesis of NiO/CoO nanostructures to enhance their low temperature oxygen reduction catalysis.

    Dan-Dan, Yu / Yong, Zhang / Hong-Quan, Yu / Hong, Zhao

    Micron (Oxford, England : 1993)

    2022  Volume 161, Page(s) 103326

    Abstract: Thermal expansion and cold contraction" are common occurrences in nature. Resulting from "thermal expansion and cold contraction" reaction, strain effect is created, which affects the oxygen reduction reaction (ORR) activities of fuel cell catalysts. ... ...

    Abstract "Thermal expansion and cold contraction" are common occurrences in nature. Resulting from "thermal expansion and cold contraction" reaction, strain effect is created, which affects the oxygen reduction reaction (ORR) activities of fuel cell catalysts. Nevertheless, the "thermal expansion and cold contraction" effects of catalysts have rarely been investigated. Herein, the influence of "thermal expansion and cold contraction" strains upon ORR activities of NiO/CoO catalysts is investigated. Experimental and first-principles calculations reveal that, when NiO/CoO are synthesized and used as catalysts under low temperature ice/water environment, there is virtually no strain effect created, and abundant active sites contribute to the good low temperature ORR activities of NiO/CoO catalysts (onset potential: 0.736 V, halfwave potential: 0.659 V). When high temperature synthesized NiO/CoO catalysts are used at low temperature, however, small amounts of active sites are created. Moreover, the adsorption activity of NiO(222) and CoO(311) stepped active sites are weakened by compressive strain of lattice contraction, which reduces their ORR activities. The "low temperature synthesis and low temperature catalysis" route proposed by this paper paves a new road for the synthesis and design of low-temperature catalysts.
    Language English
    Publishing date 2022-07-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 207808-9
    ISSN 1878-4291 ; 0047-7206 ; 0968-4328
    ISSN (online) 1878-4291
    ISSN 0047-7206 ; 0968-4328
    DOI 10.1016/j.micron.2022.103326
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    Zs.A 1927: Show issues Location:
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  4. Article ; Online: Integrin β1-rich extracellular vesicles of kidney recruit Fn1+ macrophages to aggravate ischemia-reperfusion-induced inflammation.

    Wang, Wenjuan / Ren, Xuejing / Chen, Xiangmei / Hong, Quan / Cai, Guangyan

    JCI insight

    2024  Volume 9, Issue 2

    Abstract: Ischemia-reperfusion injury-induced (IRI-induced) acute kidney injury is accompanied by mononuclear phagocyte (MP) invasion and inflammation. However, systematic analysis of extracellular vesicle-carried (EV-carried) proteins mediating intercellular ... ...

    Abstract Ischemia-reperfusion injury-induced (IRI-induced) acute kidney injury is accompanied by mononuclear phagocyte (MP) invasion and inflammation. However, systematic analysis of extracellular vesicle-carried (EV-carried) proteins mediating intercellular crosstalk in the IRI microenvironment is still lacking. Multiomics analysis combining single-cell RNA-Seq data of kidney and protein profiling of kidney-EV was used to elucidate the intercellular communication between proximal tubular cells (PTs) and MP. Targeted adhesion and migration of various MPs were caused by the secretion of multiple chemokines as well as integrin β1-rich EV by ischemic-damaged PTs after IRI. These recruited MPs, especially Fn1+ macrophagocyte, amplified the surviving PT's inflammatory response by secreting the inflammatory factors TNF-α, MCP-1, and thrombospondin 1 (THBS-1), which could interact with integrin β1 to promote more MP adhesion and interact with surviving PT to further promote the secretion of IL-1β. However, GW4869 reduced MP infiltration and maintained a moderate inflammatory level likely by blocking EV secretion. Our findings establish the molecular bases by which chemokines and kidney-EV mediate PT-MP crosstalk in early IRI and provide insights into systematic intercellular communication.
    MeSH term(s) Inflammation ; Integrin beta1 ; Ischemia ; Kidney ; Reperfusion ; Animals
    Chemical Substances Integrin beta1
    Language English
    Publishing date 2024-01-23
    Publishing country United States
    Document type Journal Article
    ISSN 2379-3708
    ISSN (online) 2379-3708
    DOI 10.1172/jci.insight.169885
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Using qualitative comparative analysis as a mixed methods synthesis in systematic mixed studies reviews: Guidance and a worked example.

    El Sherif, Reem / Pluye, Pierre / Hong, Quan Nha / Rihoux, Benoît

    Research synthesis methods

    2024  Volume 15, Issue 3, Page(s) 450–465

    Abstract: Qualitative comparative analysis (QCA) is a hybrid method designed to bridge the gap between qualitative and quantitative research in a case-sensitive approach that considers each case holistically as a complex configuration of conditions and outcomes. ... ...

    Abstract Qualitative comparative analysis (QCA) is a hybrid method designed to bridge the gap between qualitative and quantitative research in a case-sensitive approach that considers each case holistically as a complex configuration of conditions and outcomes. QCA allows for multiple conjunctural causation, implying that it is often a combination of conditions that produces an outcome, that multiple pathways may lead to the same outcome, and that in different contexts, the same condition may have a different impact on the outcome. This approach to complexity allows QCA to provide a practical understanding for complex, real-world situations, and the context of implementing interventions. There are guides for conducting QCA in primary research and quantitative systematic reviews yet, to our knowledge, no guidance for conducting QCA in systematic mixed studies reviews (SMSRs). Thus, the specific objectives of this paper are to (1) describe a step-by-step approach for novice researchers for using QCA to integrate qualitative and quantitative evidence, including guidance on how to use software; (2) highlight specific challenges; (3) propose potential solutions from a worked example; and (4) provide recommendations for reporting.
    MeSH term(s) Humans ; Research Design ; Qualitative Research ; Software ; Systematic Reviews as Topic ; Review Literature as Topic ; Data Interpretation, Statistical
    Language English
    Publishing date 2024-01-09
    Publishing country England
    Document type Journal Article ; Comparative Study
    ZDB-ID 2548499-0
    ISSN 1759-2887 ; 1759-2879
    ISSN (online) 1759-2887
    ISSN 1759-2879
    DOI 10.1002/jrsm.1698
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Identification of T-cell exhaustion-related gene signature for predicting prognosis in glioblastoma multiforme.

    Liu, Yue-Hui / Jin, Hong-Quan / Liu, Hai-Ping

    Journal of cellular and molecular medicine

    2023  Volume 27, Issue 22, Page(s) 3503–3513

    Abstract: Glioblastoma multiforme (GBM) is a highly malignant primary brain tumour with a poor prognosis in adults. Identifying biomarkers that can aid in the molecular classification and risk stratification of GBM is critical. Here, we conducted a transcriptional ...

    Abstract Glioblastoma multiforme (GBM) is a highly malignant primary brain tumour with a poor prognosis in adults. Identifying biomarkers that can aid in the molecular classification and risk stratification of GBM is critical. Here, we conducted a transcriptional profiling analysis of T-cell immunity in the tumour microenvironment of GBM patients and identified two novel T cell exhaustion (TEX)-related GBM subtypes (termed TEX-C1 and TEX-C2) using the consensus clustering. Our multi-omics analysis revealed distinct immunological, molecular and clinical characteristics for these two subtypes. Specifically, the TEX-C1 subtype had higher infiltration levels of immune cells and expressed higher levels of immune checkpoint molecules than the TEX-C2 subtype. Functional analysis revealed that upregulated genes in the TEX-C1 subtype were significantly enriched in immune response and signal transduction pathways, and upregulated genes in the TEX-C2 subtype were predominantly associated with cell fate and nervous system development pathways. Notably, patients with activated T-cell activity status in the TEX-C1 subgroup demonstrated a significantly worse prognosis than those with severe T cell exhaustion status in the TEX-C2 subgroup. Finally, we proposed a machine-learning-derived novel gene signature comprising 12 TEX-related genes (12TexSig) to indicate tumour subtyping. In the TCGA cohort, the 12TexSig demonstrated the ability to accurately predict the prognosis of GBM patients, and this prognostic value was further confirmed in two independent external cohorts. Taken together, our results suggest that the TEX-derived subtyping and gene signature has the potential to serve as a clinically helpful biomarker for guiding the management of GBM patients, pending further prospective validation.
    MeSH term(s) Adult ; Humans ; Gene Expression Profiling/methods ; Glioblastoma/pathology ; T-Cell Exhaustion ; Biomarkers ; Brain Neoplasms/pathology ; Tumor Microenvironment/genetics
    Chemical Substances Biomarkers
    Language English
    Publishing date 2023-08-27
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2074559-X
    ISSN 1582-4934 ; 1582-4934 ; 1582-1838
    ISSN (online) 1582-4934
    ISSN 1582-4934 ; 1582-1838
    DOI 10.1111/jcmm.17927
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5752: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  7. Article ; Online: Effect of A-Cation Radius on the Structure, Luminescence, and Temperature Sensing of Double Perovskites A

    Vu, Thi Hong Quan / Stefańska, Dagmara / Dereń, Przemysław Jacek

    Inorganic chemistry

    2023  Volume 62, Issue 49, Page(s) 20020–20029

    Abstract: Herein, we report a case of ... ...

    Abstract Herein, we report a case of A
    Language English
    Publishing date 2023-11-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1484438-2
    ISSN 1520-510X ; 0020-1669
    ISSN (online) 1520-510X
    ISSN 0020-1669
    DOI 10.1021/acs.inorgchem.3c02798
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  8. Article: [Therapeutic potential of targeting SIRT1 for the treatment of Alzheimer's disease].

    Shen, Li-Li / Sun, Hui-Yan / Wang, Hong-Quan

    Sheng li xue bao : [Acta physiologica Sinica

    2023  Volume 75, Issue 1, Page(s) 99–107

    Abstract: Silent information regulator 1 (SIRT1) is one of the seven mammalian proteins of the sirtuin family of ... ...

    Abstract Silent information regulator 1 (SIRT1) is one of the seven mammalian proteins of the sirtuin family of NAD
    MeSH term(s) Animals ; Alzheimer Disease ; Amyloid beta-Protein Precursor ; Animals, Genetically Modified ; Sirtuin 1 ; Sirtuins ; Humans
    Chemical Substances Amyloid beta-Protein Precursor ; Sirtuin 1 (EC 3.5.1.-) ; Sirtuins (EC 3.5.1.-)
    Language Chinese
    Publishing date 2023-03-01
    Publishing country China
    Document type Review ; English Abstract ; Journal Article
    ZDB-ID 604308-2
    ISSN 0371-0874
    ISSN 0371-0874
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 386: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  9. Article ; Online: Factors affecting organizational commitment

    Nguyen Hong Quan / Nguyen Thi Anh Tho

    Journal of International Economics and Management, Vol 22, Iss 3, Pp 91-

    research at the Joint-stock Commercial Bank for Investment and Development of Vietnam (BIDV)

    2022  Volume 109

    Abstract: The study examines the impact of six internal factors on the organizational commitment of the employees at the Bank for Investment and Development of Vietnam (BIDV). The reliability analysis and exploratory factor analysis were adopted to analyze the ... ...

    Abstract The study examines the impact of six internal factors on the organizational commitment of the employees at the Bank for Investment and Development of Vietnam (BIDV). The reliability analysis and exploratory factor analysis were adopted to analyze the collected data from 292 surveyed samples. The results show that six elements including current job, working condition, leadership, colleagues, payments and salaries, promotion and development positively relate to employees’ organizational commitment at BIDV. Based on this finding, the most important implication is the need of establishing a holistic working environment.
    Keywords human resource management ; organizational commitment ; bidv ; Economics as a science ; HB71-74
    Language English
    Publishing date 2022-11-01T00:00:00Z
    Publisher HDV INSER., JSC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Bicyclic Bridgehead Phosphoramidite-Based Hybrid Diphosphorus Ligands: Design, Synthesis, and Application in Catalytic Asymmetric Hydrogenation.

    Du, Hong-Quan / Hu, Xiang-Ping

    Organic letters

    2021  Volume 23, Issue 19, Page(s) 7678–7682

    Abstract: A strategy for chiral ligand design has been developed that allows for incorporation of an achiral bicyclic bridgehead phosphoramidite to generate a class of hybrid diphosphorus ligands for high activity and asymmetric control. Using this concept, a ... ...

    Abstract A strategy for chiral ligand design has been developed that allows for incorporation of an achiral bicyclic bridgehead phosphoramidite to generate a class of hybrid diphosphorus ligands for high activity and asymmetric control. Using this concept, a series of chiral phosphine-phosphoramidite ligands bearing the sole chirality at the ligand backbone have been prepared and successfully employed in the Rh-catalyzed asymmetric hydrogenation of 2-vinylanilides for the synthesis of optically active anilines bearing an
    Language English
    Publishing date 2021-09-21
    Publishing country United States
    Document type Journal Article
    ISSN 1523-7052
    ISSN (online) 1523-7052
    DOI 10.1021/acs.orglett.1c02978
    Database MEDical Literature Analysis and Retrieval System OnLINE

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