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  1. Book ; Online ; E-Book: Diagnostic imaging of drug resistant pulmonary tuberculosis

    Lu, Pu-Xuan / Lu, Hong-zhou / Yi, Yong-xiang

    2023  

    Author's details Pu-Xuan Lu, Hong-zhou Lu, Yong-xiang Yi editors
    Keywords Radiology
    Language English
    Size 1 Online-Ressource (xx, 267 Seiten), Illustrationen, Diagramme
    Publisher People's Medical Publishing House
    Publishing place Singapore
    Publishing country Singapore
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT030697346
    ISBN 978-981-99-8339-1 ; 9789819983384 ; 981-99-8339-8 ; 981998338X
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: The Role of Contract Farming in Green Smart Agricultural Technology

    Junjin Chen / Hong Zhou

    Sustainability, Vol 15, Iss 10600, p

    2023  Volume 10600

    Abstract: Promoting green agricultural production is becoming increasingly important in order to address resource and environmental issues and meet consumers’ demand for safe agricultural products. Green agriculture mainly refers to the adoption of green, smart ... ...

    Abstract Promoting green agricultural production is becoming increasingly important in order to address resource and environmental issues and meet consumers’ demand for safe agricultural products. Green agriculture mainly refers to the adoption of green, smart agriculture technologies in agricultural production. Farmers are the main body of agricultural production, so guiding farmers to adopt green, smart agriculture technologies is of great significance for safeguarding the ecological environment. However, due to the combined influence of internal and external factors, the current level of adoption of green, smart agriculture technologies by farmers is not high. Contract farming can have an impact on farmers’ production behavior through various channels, such as guiding and standardizing production, and may become an internal driving force for improving the adoption of green, smart agriculture technologies. How do farmers make contract farming selection decisions? How does the choice of contract farming affect farmers’ adoption of green, smart agriculture technologies? Further research on the above issues can provide useful references for promoting the development of green agriculture and ensuring the quality of agricultural products in China. Against this backdrop, this paper, using research data about rice farmers in the Jiangsu Province of China, adopted a gradual regression method for checking the mediating and moderating effects to discover the mechanism of how contract farming influences rice farmers’ choice of green, smart agriculture technologies. The research results showed that: (1) contract farming has an evidently positive influence on farmers’ choice of green, smart agriculture technologies; (2) the high ecological value standard plays a complete mediating role in the process of contract farming influencing farmers’ choice of green, smart agriculture technologies; and (3) the moderating effect of planting rice income exists and is significant. When the income from cultivation is high, the positive ...
    Keywords contract farming ; high ecological value standard ; rice cultivation ; smart agricultural technology ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
    Subject code 330
    Language English
    Publishing date 2023-07-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Does every Staphylococcus aureus infection require anti-MRSA drugs? Three case reports of a Staphylococcus aureus infection.

    Chen, Guangbin / Lu, Hong-Zhou

    Drug discoveries & therapeutics

    2023  Volume 17, Issue 2, Page(s) 144–147

    Abstract: Staphylococcus aureus is a common clinical pathogen. Does every S. aureus infection require anti-MRSA drugs? Reported here are three cases of a community-acquired infection with S. aureus. The first case involveds a 45-year-old male who was admitted due ... ...

    Abstract Staphylococcus aureus is a common clinical pathogen. Does every S. aureus infection require anti-MRSA drugs? Reported here are three cases of a community-acquired infection with S. aureus. The first case involveds a 45-year-old male who was admitted due to right ankle pain for 1 month; he was diagnosed with chronic suppurative osteomyelitis and an acute soft tissue infection of the ankle. S.aureus was cultured from the pus and was resistant to penicillin and sensitive to oxacillin and vancomycin. After receiving oxacillin, he was cured and discharged 45 days after admission. The second case involved a 44-year-old male who was admitted due to lumbar pain with right lower limb numbness for more than 1 month and fever for 1 day. S. aureus was cultured from blood specimens and was resistant to penicillin and sensitive to oxacillin and vancomycin. After receiving oxacillin, he as cured. The third case involved a 7-day-old newborn who was admitted due to skin jaundice for 6 days. S. aureus was cultured from skin secretions specimens and was resistant to penicillin and sensitive to oxacillin, erythromycin, and vancomycin. The newborn was treated with oxacillin for 4 days, and she was cured and discharged. Not all cases a suspected S. aureus infection require anti-MRSA drugs; instead, previous S. aureus susceptibility results in the area and hospital, as well as the patient's clinical profile, need to be taken into account.
    MeSH term(s) Male ; Female ; Infant, Newborn ; Humans ; Middle Aged ; Adult ; Staphylococcus aureus ; Vancomycin/pharmacology ; Vancomycin/therapeutic use ; Anti-Bacterial Agents/therapeutic use ; Microbial Sensitivity Tests ; Staphylococcal Infections/drug therapy ; Staphylococcal Infections/diagnosis ; Oxacillin/pharmacology ; Oxacillin/therapeutic use ; Methicillin-Resistant Staphylococcus aureus
    Chemical Substances Vancomycin (6Q205EH1VU) ; Anti-Bacterial Agents ; Oxacillin (UH95VD7V76)
    Language English
    Publishing date 2023-04-09
    Publishing country Japan
    Document type Case Reports ; Journal Article
    ZDB-ID 2568828-5
    ISSN 1881-784X ; 1881-784X
    ISSN (online) 1881-784X
    ISSN 1881-784X
    DOI 10.5582/ddt.2022.01102
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Using cryoEM and cryoET to visualize membrane penetration of a non-enveloped virus

    Xian Xia / Z. Hong Zhou

    STAR Protocols, Vol 3, Iss 4, Pp 101825- (2022)

    2022  

    Abstract: Summary: Key to cell entry by non-enveloped viruses is virus-cell interactions at the cell or endosomal membrane. Here, we detail our protocols to capture such interactions between non-enveloped virus bluetongue virus (BTV) and vesicular membrane by ... ...

    Abstract Summary: Key to cell entry by non-enveloped viruses is virus-cell interactions at the cell or endosomal membrane. Here, we detail our protocols to capture such interactions between non-enveloped virus bluetongue virus (BTV) and vesicular membrane by cryogenic electron microscopy (cryoEM) and tomography (cryoET). Key steps include virus isolation, liposome preparation, virus-liposome incubation and vitrification, cryoEM and cryoET imaging, data processing for 3D reconstruction, and subtomogram averaging. The protocols can be generally applicable to studies of cell entry by other non-enveloped viruses.For complete details on the use and execution of this protocol, please refer to Xia et al. (2021). : Publisher’s note: Undertaking any experimental protocol requires adherence to local institutional guidelines for laboratory safety and ethics.
    Keywords Microbiology ; Microscopy ; Structural biology ; Cryo-EM ; Science (General) ; Q1-390
    Language English
    Publishing date 2022-12-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Incentives to Enhance Production Reliability against Disruption

    Xiaodan Jin / Hong Zhou

    Sustainability, Vol 14, Iss 15, p

    Cost-Sharing vs. Penalty

    2022  Volume 9003

    Abstract: Two kinds of incentive strategies, cost-sharing and penalty, are examined in dealing with production disruption, with consideration of production process reliability as an endogenous factor for a two-echelon supply chain. Based on the Stackelberg game ... ...

    Abstract Two kinds of incentive strategies, cost-sharing and penalty, are examined in dealing with production disruption, with consideration of production process reliability as an endogenous factor for a two-echelon supply chain. Based on the Stackelberg game framework, we derive the optimal decisions of supply chain partners and compare their expected profits with different strategies. Considering the uncertain demand and the retailer’s preference against the risk, we further analyze how the partners’ decisions and the retailer’s expected profit are influenced by the feature of loss aversion. From theoretical analysis and numerical experiments, we find that: (1) overall, a penalty strategy dominates that of cost-sharing for the retailer, whereas the reverse applies with respect to the manufacturer; (2) a penalty strategy may outperform a cost-sharing strategy for the whole supply chain, depending on demand; and (3) a reasonable aversion against risk can help the retailer to achieve a more robust result when a penalty strategy is adopted under volatile and unpredictable demand.
    Keywords production disruption ; production process reliability ; incentive strategies ; loss-averse ; Stackelberg game ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
    Subject code 670
    Language English
    Publishing date 2022-07-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Are vulnerable farmers more easily influenced? Heterogeneous effects of Internet use on the adoption of integrated pest management

    Kai LI / Yu JIN / Jie-hong ZHOU

    Journal of Integrative Agriculture, Vol 22, Iss 10, Pp 3220-

    2023  Volume 3233

    Abstract: The Internet is believed to bring more technological dividends to vulnerable farmers during the green agriculture transformation. However, this is different from the theory of skill-biased technological change, which emphasizes that individuals with ... ...

    Abstract The Internet is believed to bring more technological dividends to vulnerable farmers during the green agriculture transformation. However, this is different from the theory of skill-biased technological change, which emphasizes that individuals with higher levels of human capital and more technological endowments benefit more. This study investigates the effects of Internet use on farmers’ adoption of integrated pest management (IPM), theoretically and empirically, based on a dataset containing 1 015 farmers in China's Shandong Province. By exploring the perspective of rational inattention, the reasons for the heterogeneity of the effects across farmers with different endowments, i.e., education and land size, are analyzed. The potential endogeneity issues are addressed using the endogenous switching probit model. The results reveal that: (1) although Internet use significantly positively affects farmers’ adoption of IPM, vulnerable farmers do not benefit more from it. Considerable selection bias leads to an overestimation of technological dividends for vulnerable farmers; (2) different sources of technology information lead to the difference in the degree of farmers’ rational inattention toward Internet information, which plays a crucial role in the heterogeneous effect of Internet use; and (3) excessive dependence on strong-tie social network information sources entraps vulnerable farmers in information cocoons, hindering their ability to reap the benefits of Internet use fully. Therefore, it is essential to promote services geared towards elderly-oriented Internet agricultural technology information and encourage farmers with strong Internet utilization skills to share technology information with other farmers actively.
    Keywords Internet use ; IPM ; vulnerable farmers ; technological dividends ; endogenous switching probit model ; Agriculture (General) ; S1-972
    Subject code 303
    Language English
    Publishing date 2023-10-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Management of massive airway hemorrhage associated with extracorporeal membrane oxygenation

    Hong Zhou / Qindong Shi / Litao Guo

    Health Science Reports, Vol 6, Iss 6, Pp n/a-n/a (2023)

    A retrospective case series study

    2023  

    Abstract: Abstract Background and Aims Extracorporeal membrane oxygenation (ECMO) is an important means of treating patients with respiratory failure. Massive airway hemorrhage is a rare complication of ECMO, with high mortality. The aim of this study was to ... ...

    Abstract Abstract Background and Aims Extracorporeal membrane oxygenation (ECMO) is an important means of treating patients with respiratory failure. Massive airway hemorrhage is a rare complication of ECMO, with high mortality. The aim of this study was to provide a reference for improving the success rate of treatment of this complication by analyzing and summarizing patient clinical data. Methods We searched PubMed, Medline, and EMBASE databases for case reports of massive airway bleeding associated with ECMO from January 2000 to January 2022 and included one case treated at our facility. All patients were disconnected from the ventilator, and the endotracheal tube was clamped during treatment, resulting in complete airway packing for hemostasis. The clinical data of these patients were analyzed. Results Through searching and further screening, two works of literature reported four cases that met our inclusion criteria. Including our patient's case, five patients were included in this study (four adults and one neonate). The longest ECMO treatment time before bleeding was 14 days, and the shortest was 20 min. In all patients, conservative treatment was ineffective after a major airway hemorrhage. They were disconnected from the ventilator and the tracheal tube was clamped for 13–72 h. The four adult patients underwent bronchial artery embolization in the interventional radiology suite. All patients' bleeding stopped after treatment; they were successfully weaned off ECMO and discharged. Conclusions Treatment measures to disconnect the ventilator and clamp the endotracheal tube with full support from ECMO are feasible for massive airway bleeding associated with ECMO. Early bronchial arteriography and embolization can prevent rebleeding.
    Keywords bleeding ; cryotherapy ; ECMO ; extracorporeal membrane oxygenation ; hemoptysis ; Medicine ; R
    Subject code 610
    Language English
    Publishing date 2023-06-01T00:00:00Z
    Publisher Wiley
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Brain abscess due to Aggregatibacter aphrophilus in association with atrial septal defect:Case report and literature review.

    Chen, Guang-Bin / Lu, Hong-Zhou

    Clinical neurology and neurosurgery

    2022  Volume 219, Page(s) 107337

    Abstract: Background: Aggregatibacter aphrophilus(A. aphrophilus)is one of the organisms of the HACEK group. Previously reported cases of brain abscesses caused by A. aphrophilus infection have occurred in children with a basis for congenital heart disease, or in ...

    Abstract Background: Aggregatibacter aphrophilus(A. aphrophilus)is one of the organisms of the HACEK group. Previously reported cases of brain abscesses caused by A. aphrophilus infection have occurred in children with a basis for congenital heart disease, or in adults with a basis for dental disease. Rare cases of brain abscess caused by A. aphrophilus have been reported in adults with congenital heart disease or in patients without dental disease history. Herein we present a rare case of brain abscess caused by A. aphrophilus, who was in association with atrial septal defect for more than 20 years, and had no dental disease and did not develop infective endocarditis.
    Case presentation: A 51-year-old female was admitted due to progressively worsening headache and left limb weakness for more than 10 days. She denied the history of chronic diseases such as hypertension and diabetes, and no periodontal disease. While she had a history of atrial septal defect, a form of congenital heart disease with severe pulmonary hypertension for more than 20 years. After admission, echocardiographic illustrated congenital heart disease with severe pulmonary hypertension. CT and MRI showed brain abscess. Cerebrospinal fluid (CSF) results also confirmed the presence of intracranial infection. Empirical therapy with vancomycin 1.0 g i.v q12h and meropenem 2.0 g i.v q8h was initiated from the day of admission. On the fourth day after admission, brain abscess resection and decompressive craniectomy were performed, and the pus drained on operation were cultured and Gram-negative bacilli grew, which was identified as A.aphrophilus. Vancomycin was discontinued and meropenem was continued(2.0 g i.v q8h)for 5 weeks, followed by oral levofloxacin 0.5 qd for 4 weeks of out-patient antibiotics. The patient recovered fully within 9 weeks of treatment.
    Conclusions: This is the first case of A. aphrophilus to cause brain abscess in adult with a history of congenital heart disease for more than 20 years, who had no dental disease and did not develop infective endocarditis. We also highlight the value of bacterial 16 S rDNA PCR amplification and sequencing in identifying bacteria in abscesses which are culture-negative, and prompt surgical treatment,choosing effective antibiotics and appropriate course of treatment will get better clinical effect.
    MeSH term(s) Adult ; Aggregatibacter aphrophilus ; Anti-Bacterial Agents/therapeutic use ; Brain Abscess/diagnostic imaging ; Brain Abscess/drug therapy ; Brain Abscess/surgery ; Child ; Endocarditis/complications ; Endocarditis/drug therapy ; Female ; Heart Defects, Congenital/complications ; Heart Defects, Congenital/drug therapy ; Heart Septal Defects, Atrial/complications ; Heart Septal Defects, Atrial/drug therapy ; Heart Septal Defects, Atrial/surgery ; Humans ; Hypertension, Pulmonary/complications ; Hypertension, Pulmonary/drug therapy ; Meropenem/therapeutic use ; Middle Aged ; Pasteurellaceae Infections/complications ; Pasteurellaceae Infections/drug therapy ; Pasteurellaceae Infections/microbiology ; Vancomycin/therapeutic use
    Chemical Substances Anti-Bacterial Agents ; Vancomycin (6Q205EH1VU) ; Meropenem (FV9J3JU8B1)
    Language English
    Publishing date 2022-06-11
    Publishing country Netherlands
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 193107-6
    ISSN 1872-6968 ; 0303-8467
    ISSN (online) 1872-6968
    ISSN 0303-8467
    DOI 10.1016/j.clineuro.2022.107337
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Correlation-Consistent Gaussian Basis Sets for Solids Made Simple.

    Ye, Hong-Zhou / Berkelbach, Timothy C

    Journal of chemical theory and computation

    2022  Volume 18, Issue 3, Page(s) 1595–1606

    Abstract: The rapidly growing interest in simulating condensed-phase materials using quantum chemistry methods calls for a library of high-quality Gaussian basis sets suitable for periodic calculations. Unfortunately, most standard Gaussian basis sets commonly ... ...

    Abstract The rapidly growing interest in simulating condensed-phase materials using quantum chemistry methods calls for a library of high-quality Gaussian basis sets suitable for periodic calculations. Unfortunately, most standard Gaussian basis sets commonly used in molecular simulation show significant linear dependencies when used in close-packed solids, leading to severe numerical issues that hamper the convergence to the complete basis set (CBS) limit, especially in correlated calculations. In this work, we revisit Dunning's strategy for construction of correlation-consistent basis sets and examine the relationship between accuracy and numerical stability in periodic settings. We find that limiting the number of primitive functions avoids the appearance of problematic small exponents while still providing smooth convergence to the CBS limit. As an example, we generate double-, triple-, and quadruple-ζ correlation-consistent Gaussian basis sets for periodic calculations with Goedecker-Teter-Hutter (GTH) pseudopotentials. Our basis sets cover the main-group elements from the first three rows of the periodic table. Especially for atoms on the left side of the periodic table, our basis sets are less diffuse than those used in molecular calculations. We verify the fast and reliable convergence to the CBS limit in both Hartree-Fock and post-Hartree-Fock (MP2) calculations, using a diverse test set of 19 semiconductors and insulators.
    Language English
    Publishing date 2022-02-22
    Publishing country United States
    Document type Journal Article
    ISSN 1549-9626
    ISSN (online) 1549-9626
    DOI 10.1021/acs.jctc.1c01245
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Drebrin Protects Assembled Actin from INF2-FFC-mediated Severing and Stabilizes Cell Protrusions.

    Rajan, Sudeepa / Aguirre, Roman / Hong Zhou, Z / Hauser, Peter / Reisler, Emil

    Journal of molecular biology

    2023  Volume 436, Issue 4, Page(s) 168421

    Abstract: Highly specialized cells, such as neurons and podocytes, have arborized morphologies that serve their specific functions. Actin cytoskeleton and its associated proteins are responsible for the distinctive shapes of cells. The mechanism of their ... ...

    Abstract Highly specialized cells, such as neurons and podocytes, have arborized morphologies that serve their specific functions. Actin cytoskeleton and its associated proteins are responsible for the distinctive shapes of cells. The mechanism of their cytoskeleton regulation - contributing to cell shape maintenance - is yet to be fully clarified. Inverted formin 2 (INF2), one of the modulators of the cytoskeleton, is an atypical formin that can both polymerize and depolymerize actin filaments depending on its molar ratio to actin. Prior work has established that INF2 binds to the sides of actin filaments and severs them. Drebrin is another actin-binding protein that also binds filaments laterally and stabilizes them, but the interplay between drebrin and INF2 on actin filament stabilization is not well understood. Here, we have used biochemical assays, electron microscopy, and total internal reflection fluorescence microscopy imaging to show that drebrin protects actin filaments from severing by INF2 without inhibiting its polymerization activity. Notably, truncated drebrin - DrbA1-300 - is sufficient for this protection, though not as effective as the full-length protein. INF2 and drebrin are abundantly expressed in highly specialized cells and are crucial for the temporal regulation of their actin cytoskeleton, consistent with their involvement in peripheral neuropathy.
    MeSH term(s) Actin Cytoskeleton/chemistry ; Actins/chemistry ; Formins/chemistry ; Neuropeptides/chemistry ; Cell Surface Extensions/chemistry ; Neurons/metabolism ; Microscopy, Electron
    Chemical Substances Actins ; drebrins ; Formins ; Neuropeptides ; INF2 protein, human
    Language English
    Publishing date 2023-12-27
    Publishing country Netherlands
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 80229-3
    ISSN 1089-8638 ; 0022-2836
    ISSN (online) 1089-8638
    ISSN 0022-2836
    DOI 10.1016/j.jmb.2023.168421
    Database MEDical Literature Analysis and Retrieval System OnLINE

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