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Article ; Online: Leisure-Related Social Work Interventions for Patients with Cognitive Impairment

Hui Yang / Zhezhen Lv / Yuyue Xu / Honglin Chen

International Journal of Environmental Research and Public Health, Vol 20, Iss 1906, p

A Systematic Review and Meta-Analysis

2023 Volume 1906

Abstract: The social work profession has been exploring nonpharmacological interventions for patients with cognitive impairment, but there are few evidence-based research outputs. Systematically evaluating the effectiveness of social work interventions for people ... ...

Abstract	The social work profession has been exploring nonpharmacological interventions for patients with cognitive impairment, but there are few evidence-based research outputs. Systematically evaluating the effectiveness of social work interventions for people with cognitive impairment can shed light on the matter to further improve similar interventions. Randomized controlled trials of nonpharmacological interventions for patients with cognitive impairment were selected from key literature databases in both English and Chinese from 2010 to 2021. A systematic review and meta-analysis with Revman 5.4 were performed. Seven trials were included, involving 851 patients with cognitive impairment. The meta-analysis showed that, in terms of overall cognitive function, the Montreal Cognitive Assessment score (MD = 1.64, 95% CI [0.97, 2.30], p < 0.001) of the intervention group was superior to the control group, but there was no significant difference in the Mini-Mental State Examination score between the two groups (MD = 0.33, 95% CI [−0.16, 0.82], p = 0.18). Compared with the control group, nonpharmacological intervention can effectively improve the neuropsychiatric condition of patients (SMD = −0.42, 95% CI [−0.64, −0.20], p = 0.0002). In summary, the current evidence shows that nonpharmacological social work interventions had a positive effect on the cognitive function and neuropsychiatric status of patients with cognitive impairment. Suggestions for future nonpharmacological intervention practice are discussed.
Keywords	nonpharmacological intervention ; social work ; cognitive impairment ; systematic review ; meta-analysis ; Medicine ; R
Subject code	616
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: A GNSS/LiDAR/IMU Pose Estimation System Based on Collaborative Fusion of Factor Map and Filtering

Honglin Chen / Wei Wu / Si Zhang / Chaohong Wu / Ruofei Zhong

Remote Sensing, Vol 15, Iss 790, p

2023 Volume 790

Abstract: One of the core issues of mobile measurement is the pose estimation of the carrier. The classic Global Navigation Satellite System/Inertial Measurement Unit (GNSS/IMU) integrated navigation scheme has high positioning accuracy but is vulnerable to Global ...

Abstract	One of the core issues of mobile measurement is the pose estimation of the carrier. The classic Global Navigation Satellite System/Inertial Measurement Unit (GNSS/IMU) integrated navigation scheme has high positioning accuracy but is vulnerable to Global Navigation Satellite System (GNSS) signal occlusion and multipath effect. Simultaneous Localization and Mapping (SLAM) is not affected by signal occlusion, but there are problems such as error accumulation and scene degradation. The multi-sensor fusion scheme combining the two technologies can effectively expand the scene coverage and improve the positioning accuracy and system robustness. However, the current scheme has some limitations. On the one hand, GNSS plays a less important role in most SLAM systems, only for initialization or as a closed-loop factor and other auxiliary work. On the other hand, in the fusion method, most of the current systems only use filtering or graph optimization, without taking into account the advantages of both. Aiming at pose estimation for mobile carriers, this paper combines the advantages of the global optimization of the factor graph and the local optimization of filtering and proposes a GNSS-IMU-LiDAR Constraint Kalman Filter (abbreviated as GIL-CKF), which has the characteristics of full coverage and effectively improving absolute accuracy and high output frequency. The scheme proposed in this paper consists of three parts. Firstly, an extensible factor map is used to fuse the positioning information from different sources, including GNSS, IMU, LiDAR, and a closed-loop map, to maintain a high-precision SLAM system, and the output is used as Multi-Sensor-Fusion-Odometry (MSFO). Then, the scene is divided according to the GNSS quality factor, and a Scene Optimizer (SO) is designed to filter GNSS pose and MSFO. Finally, the results are input into the Extended Kalman Filter (EKF) together with the original IMU data for further optimization and smoothing. The experimental results show that the integration of high-precision GNSS ...
Keywords	fusion positioning ; GNSS/LiDAR/IMU ; factor graph ; EKF filtering ; Science ; Q
Subject code	629
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Integrated Nonpharmacological Intervention for Patients with MCI—A Preliminary Study in Shanghai, China

Hui Yang / Yinghong Liu / Honglin Chen / You Yin

International Journal of Integrated Care, Vol 22, Iss

2022 Volume 1

Abstract: Objective: Mild cognitive impairment is a transitional state between normal aging and Alzheimer’s and is an internationally recognized pre-stage state of Alzheimer’s. It is the starting point for early detection and intervention in dementia. An empirical ...

Abstract	Objective: Mild cognitive impairment is a transitional state between normal aging and Alzheimer’s and is an internationally recognized pre-stage state of Alzheimer’s. It is the starting point for early detection and intervention in dementia. An empirical study was conducted to determine how medical social workers provide intervention services to older adults with mild cognitive impairment, specific strategies for change, and the effectiveness of the intervention. Methods: This was a quasi-experimental intervention study. Conclusion: Through integrated intervention, the development of cognitive impairment can be significantly delayed, cognitive abilities can be improved ('p' < .05), and decline in daily living abilities can be significantly delayed ('p' < .05). At the same time, the mental health of participants can be improved to a certain extent.
Keywords	mild cognitive impairment ; social work ; integrated nonpharmacological intervention ; multicomponent nonpharmacological intervention approach ; Medicine (General) ; R5-920
Subject code	796
Language	English
Publishing date	2022-03-01T00:00:00Z
Publisher	Ubiquity Press
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Zoonotic attack

Lin Zhu / Honglin Chen / Zongwei Cai

The Innovation, Vol 3, Iss 3, Pp 100242- (2022)

An underestimated threat of SARS-CoV-2?

2022

Keywords	Science (General) ; Q1-390
Language	English
Publishing date	2022-05-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Social Isolation, Cognitive Function, and Depression Among Chinese Older Adults

Yunjun Li / Xiao Bai / Honglin Chen

Frontiers in Public Health, Vol

Examining Internet Use as a Predictor and a Moderator

2022 Volume 10

Abstract: ObjectivesDespite the theoretical and practical interest in Internet use among older adults, evidence examining the impacts of Internet use on late-in-life health is limited. This study examines how Internet use affects depression and cognitive function ... ...

Abstract	ObjectivesDespite the theoretical and practical interest in Internet use among older adults, evidence examining the impacts of Internet use on late-in-life health is limited. This study examines how Internet use affects depression and cognitive function in older adults and investigates if Internet use moderates the relationship between social isolation and depression/cognitive function.MethodWe performed regression analyses using data came from the second wave of the China Longitudinal Aging Social Survey of 2016. Our final sample featured 8,835 older adults.ResultsThe results show 11.4% of Chinese older adults often used the Internet to engage in at least one activity. Internet use was negatively associated with depression, but it was positively related to cognitive function. Socially isolated older adults were more likely to have more depressive symptoms and higher level of cognitive function. There was also an interaction effect between Internet use and social isolation on depression/cognitive function. The negative effect of social isolation was stronger for older adults who used the Internet less. The moderating effect of Internet use was significant for both males and females. However, among those who used the Internet more, the depression levels of socially isolated male participants were much lower than female participants.ConclusionsOur results reveal the importance of considering Internet use in buffering the negative effects of social isolation and the associated health burdens for aging populations. Recommendations for service practice and future research are discussed.
Keywords	Internet use ; social isolation ; older adults ; cognitive function ; depression ; Public aspects of medicine ; RA1-1270
Subject code	300
Language	English
Publishing date	2022-03-01T00:00:00Z
Publisher	Frontiers Media S.A.
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Energy Storage Capacity Planning Method for Improving Offshore Wind Power Consumption

Hao Yu / Xiaojuan Yang / Honglin Chen / Suhua Lou / Yong Lin

Sustainability, Vol 14, Iss 14589, p

2022 Volume 14589

Abstract: This paper proposes a method of energy storage capacity planning for improving offshore wind power consumption. Firstly, an optimization model of offshore wind power storage capacity planning is established, which takes into account the annual load ... ...

Abstract	This paper proposes a method of energy storage capacity planning for improving offshore wind power consumption. Firstly, an optimization model of offshore wind power storage capacity planning is established, which takes into account the annual load development demand, the uncertainty of offshore wind power, various types of power sources and line structure. The model aims at the lowest cost of investment, operation and maintenance of the system, and takes lower than a certain abandoned wind level as the strict constraint to obtain two parameters of power capacity and energy capacity of energy storage on the source side. Secondly, taking a coastal power grid as a typical case, the energy storage capacity planning method is verified. Finally, the key factors affecting offshore wind power consumption are summarized, and the sensitivity analysis is carried out from the point of view of the transmission protocol of the transmission lines outside the province and the capacity allocation of the tie lines in the province. This study will be helpful for the planning and operation of the high-proportion of offshore wind energy power systems.
Keywords	offshore wind power ; energy storage system ; wind power consumption ; planning optimization model ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
Subject code	690
Language	English
Publishing date	2022-11-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: A Novel Method for Intrinsic and Extrinsic Parameters Estimation by Solving Perspective-Three-Point Problem with Known Camera Position

Kai Guo / Hu Ye / Junhao Gu / Honglin Chen

Applied Sciences, Vol 11, Iss 6014, p

2021 Volume 6014

Abstract: The aim of the perspective-three-point (P3P) problem is to estimate extrinsic parameters of a camera from three 2D–3D point correspondences, including the orientation and position information. All the P3P solvers have a multi-solution phenomenon that is ... ...

Abstract	The aim of the perspective-three-point (P3P) problem is to estimate extrinsic parameters of a camera from three 2D–3D point correspondences, including the orientation and position information. All the P3P solvers have a multi-solution phenomenon that is up to four solutions and needs a fully calibrated camera. In contrast, in this paper we propose a novel method for intrinsic and extrinsic parameter estimation based on three 2D–3D point correspondences with known camera position. Our core contribution is to build a new, virtual camera system whose frame and image plane are defined by the original 3D points, to build a new, intermediate world frame by the original image plane and the original 2D image points, and convert our problem to a P3P problem. Then, the intrinsic and extrinsic parameter estimation is to solve frame transformation and the P3P problem. Lastly, we solve the multi-solution problem by image resolution. Experimental results show its accuracy, numerical stability and uniqueness of the solution for intrinsic and extrinsic parameter estimation in synthetic data and real images.
Keywords	perspective-three-point problem ; intrinsic and extrinsic parameters estimation ; new camera system ; unique solution ; Technology ; T ; Engineering (General). Civil engineering (General) ; TA1-2040 ; Biology (General) ; QH301-705.5 ; Physics ; QC1-999 ; Chemistry ; QD1-999
Subject code	620
Language	English
Publishing date	2021-06-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: C/EBPβ Coupled with E2F2 Promoted the Proliferation of hESC-Derived Hepatocytes through Direct Binding to the Promoter Regions of Cell-Cycle-Related Genes

Shoupei Liu / Jue Wang / Sen Chen / Zonglin Han / Haibin Wu / Honglin Chen / Yuyou Duan

Cells, Vol 12, Iss 497, p

2023 Volume 497

Abstract: Human embryonic stem cells (hESCs) hold the potential to solve the problem of the shortage of functional hepatocytes in clinical applications and drug development. However, a large number of usable hepatocytes derived from hESCs cannot be effectively ... ...

Abstract	Human embryonic stem cells (hESCs) hold the potential to solve the problem of the shortage of functional hepatocytes in clinical applications and drug development. However, a large number of usable hepatocytes derived from hESCs cannot be effectively obtained due to the limited proliferation capacity. In this study, we found that enhancement of liver transcription factor C/EBPβ during hepatic differentiation could not only significantly promote the expression of hepatic genes, such as albumin, alpha fetoprotein, and alpha-1 antitrypsin, but also dramatically reinforce proliferation-related phenotypes, including increasing the expression of proliferative genes, such as CDC25C, CDC45L, and PCNA, and the activation of cell cycle and DNA replication pathways. In addition, the analysis of CUT&Tag sequencing further revealed that C/EBPβ is directly bound to the promoter region of proliferating genes to promote cell proliferation; this interaction between C/EBPβ and DNA sequences of the promoters was verified by luciferase assay. On the contrary, the knockdown of C/EBPβ could significantly inhibit the expression of the aforementioned proliferative genes. RNA transcriptome analysis and GSEA enrichment indicated that the E2F family was enriched, and the expression of E2F2 was changed with the overexpression or knockdown of C/EBPβ. Moreover, the results of CUT&Tag sequencing showed that C/EBPβ also directly bound the promoter of E2F2, regulating E2F2 expression. Interestingly, Co-IP analysis exhibited a direct binding between C/EBPβ and E2F2 proteins, and this interaction between these two proteins was also verified in the LO2 cell line, a hepatic progenitor cell line. Thus, our results demonstrated that C/EBPβ first initiated E2F2 expression and then coupled with E2F2 to regulate the expression of proliferative genes in hepatocytes during the differentiation of hESCs. Therefore, our findings open a new avenue to provide an in vitro efficient approach to generate proliferative hepatocytes to potentially meet the ...
Keywords	human embryonic stem cells ; liver enriched transcription factor ; C/EBPβ ; E2F ; hepatocyte differentiation ; cell cycle ; Biology (General) ; QH301-705.5
Subject code	570
Language	English
Publishing date	2023-02-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Studies on the Digital Inclusion Among Older Adults and the Quality of Life—A Nanjing Example in China

Hui Yang / Hongtu Chen / Tianshu Pan / Yiran Lin / Ying Zhang / Honglin Chen

Frontiers in Public Health, Vol

2022 Volume 10

Abstract: Digital inclusion can bridge the digital divide and reduce the social exclusion of older adults, yet it is understudied in China. This research examined factors influencing the digital inclusion of older adults in China and the relationship between ... ...

Abstract	Digital inclusion can bridge the digital divide and reduce the social exclusion of older adults, yet it is understudied in China. This research examined factors influencing the digital inclusion of older adults in China and the relationship between digital inclusion and quality of life. Data collected from 312 older people (M = 69.6 years old) in Nanjing were included in a multinomial logit model to tackle these questions. Their attitudes toward technology were the most significant factor predicting their digital inclusion. Other factors included party affiliation, living situation, personal average monthly income, occupation, and capacity for instrumental activities of daily living (IADLs). This study shows digital inclusion has a direct impact on quality of life. It also serves as an intermediate variable that affects older people's attitudes toward technology and their IADL capacities. Most importantly, digital inclusion promotes social integration of older adults and improves the quality of their lives. Hence, it should not be ignored. Older people's attitudes toward technology are one of the keys to promoting their digital inclusion.
Keywords	digital inclusion ; quality of life ; multinomial logit model ; older adults ; Nanjing ; Public aspects of medicine ; RA1-1270
Subject code	390
Language	English
Publishing date	2022-05-01T00:00:00Z
Publisher	Frontiers Media S.A.
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Evaluation of the Production Potential of Mung Bean Cultivar “Zhonglv 5”

Lixia Wang / Suhua Wang / Gaoling Luo / Jintao Zhang / Yanhua Chen / Honglin Chen / Xuzhen Cheng

Agronomy, Vol 12, Iss 707, p

2022 Volume 707

Abstract: High yields, high stress resistance, and wide adaptability are important cultivar traits, especially for crops sensitive to the photoperiod and temperature. Mung bean ( Vigna radiata ) is a typical short-day plant, traditionally cultivated in Asian ... ...

Abstract	High yields, high stress resistance, and wide adaptability are important cultivar traits, especially for crops sensitive to the photoperiod and temperature. Mung bean ( Vigna radiata ) is a typical short-day plant, traditionally cultivated in Asian countries, and consumed all over the world. However, there has long been relatively little research regarding its genetic improvement until in recent decades. Zhonglv 5 is a mung bean cultivar that was developed via crossbreeding in China in the early part of this century. It has since played an important role in improving mung bean production in the country because of its high yields, high stress tolerance, and wide adaptability. We herein describe the development of Zhonglv 5, summarize its yield performance and adaptability in diverse eco-regions within China, and predict its potential future uses to provide information relevant for mung bean breeding, production, trade, and related industries.
Keywords	mung bean ; development ; Zhonglv 5 ; high yield ; adaptability ; Agriculture ; S
Language	English
Publishing date	2022-03-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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