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  1. Article ; Online: Knowledge Mapping of Tourist Experience Research

    Hongmei Guan / Taozhen Huang / Xin Guo

    SAGE Open, Vol

    Based on CiteSpace Analysis

    2023  Volume 13

    Abstract: Tourist experience research has been increasing in practitioners and academics. The study collected 1,079 tourist experience related articles published in the Web of Science (WOS) core database to summarize research on tourist experience from 2007 to ... ...

    Abstract Tourist experience research has been increasing in practitioners and academics. The study collected 1,079 tourist experience related articles published in the Web of Science (WOS) core database to summarize research on tourist experience from 2007 to 2019 and to explore research hotspots and trends related to the topic. CiteSpace analysis was used from the selected 1,045 articles to identify and visualize the evolution of knowledge. The results revealed that the major disciplines for research tourist experience are Hospitality Leisure Sport Tourism disciplines. The most influential authors are mostly from high-yield institutions. The high-yield countries (regions) are in the USA, China, Australia, England and Italy. In addition, three hotspots research topics and contemporary trends are presented.
    Keywords History of scholarship and learning. The humanities ; AZ20-999 ; Social Sciences ; H
    Language English
    Publishing date 2023-04-01T00:00:00Z
    Publisher SAGE Publishing
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Establishment of human-induced pluripotent stem cell GZHMCi0011-A from peripheral blood mononuclear cells from a volunteer with 14/63 CAG repeats of the ATXN3 mutation.

    Hongmei, Guan / Xiaofang, Sun / Bing, Song

    Stem cell research

    2023  Volume 72, Page(s) 103190

    Abstract: Spinocerebellar ataxia type 3 (SCA3) is a genetic degeneration disease of the nervous system with ataxia as the main clinical manifestation, and the most frequent subtype of SCA3 is known to be caused by CAG repeat expansions of more than 55 units in ... ...

    Abstract Spinocerebellar ataxia type 3 (SCA3) is a genetic degeneration disease of the nervous system with ataxia as the main clinical manifestation, and the most frequent subtype of SCA3 is known to be caused by CAG repeat expansions of more than 55 units in ATXN3. In this study, we used peripheral blood mononuclear cells (PBMCs) from a volunteer with 14/63 CAG repeats in ATXN3 to generate induced pluripotent stem cells (iPSCs), which will be a good model for studying SCA3.
    MeSH term(s) Humans ; Induced Pluripotent Stem Cells/metabolism ; Leukocytes, Mononuclear/metabolism ; Ataxin-3/genetics ; Ataxin-3/metabolism ; Machado-Joseph Disease/genetics ; Machado-Joseph Disease/metabolism ; Mutation/genetics ; Volunteers ; Repressor Proteins/genetics
    Chemical Substances Ataxin-3 (EC 3.4.19.12) ; ATXN3 protein, human (EC 3.4.19.12) ; Repressor Proteins
    Language English
    Publishing date 2023-08-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 2393143-7
    ISSN 1876-7753 ; 1873-5061
    ISSN (online) 1876-7753
    ISSN 1873-5061
    DOI 10.1016/j.scr.2023.103190
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Contrast media extravasation injury

    Wanli Liu / Pinghu Wang / Hui Zhu / Hui Tang / Hongmei Guan / Xiaoying Wang / Chengxiang Wang / Yao Qiu / Lianxiang He

    European Journal of Medical Research, Vol 28, Iss 1, Pp 1-

    a prospective observational cohort study

    2023  Volume 8

    Abstract: Abstract Objective To identify the risk factors for moderate and severe contrast media extravasation and provide effective guidance to reduce the degree of extravasation injuries. Methods We observed 224 adult patients who underwent contrast media ... ...

    Abstract Abstract Objective To identify the risk factors for moderate and severe contrast media extravasation and provide effective guidance to reduce the degree of extravasation injuries. Methods We observed 224 adult patients who underwent contrast media extravasation at Xiangya Hospital of Central South University, Hunan Provincial Maternal and Child Healthcare Hospital, and Xiangya Changde Hospital, Hunan Province between January 1, 2018 and December 31, 2022. Risk factors for moderate extravasation injuries were evaluated using univariate and multivariate logistic regression. Results Among 224 patients, 0 (0%) had severe, 18 (8.0%) had moderate, and 206 (92.0%) had mild contrast media extravasation injury. Multivariate logistic regression analysis revealed malignant tumors (odds ratio [OR] = 6.992, 95% confidence interval [CI]: 1.674–29.208), Iohexol (OR = 9.343, 95% CI 1.280–68.214), large-volume (> 50 mL) extravasation (OR = 5.773, 95% CI 1.350‒24.695), and injection site (back of the hand) (OR = 13.491, 95% CI 3.056–59.560) as independent risk factors for moderate injury. Conclusion Risk factors for moderate contrast media extravasation injury are malignant tumors, iohexol, large-volume (> 50 mL) extravasation, and back-of-the-hand injection. Analysis of these risk factors can help reduce the degree of injury after extravasation. Clinical relevance statement High-risk patients with extravasation support should choose the appropriate contrast media type, avoiding back-of-the-hand injections. We recommend that patients with cancer be implanted with a high-pressure resistant central venous catheter and receive effective measures to timely detect and reduce extravasation.
    Keywords Contrast media ; Extravasation ; Moderate extravasation injury ; Risk factor ; Medicine ; R
    Subject code 610
    Language English
    Publishing date 2023-10-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Generation of induced pluripotent stem cell line GZHMCi006-A from amniotic fluid-derived cells with deletion 14q syndrome

    Bing Song / Yi Cheng / Dingya Cao / Nengqing Liu / Hongmei Guan / Lili Du / Huimin Zhang / Yi Liang / Jiajia Xian / Xiaofang Sun

    Stem Cell Research, Vol 53, Iss , Pp 102315- (2021)

    2021  

    Abstract: The deletions of the long arm of chromosome 14 involving the 14q24-q32 region have been identified as deletion 14q (del 14q) syndrome, but were rarely reported. The patients with del 14q syndrome are observed a peculiar facial appearance and neurological ...

    Abstract The deletions of the long arm of chromosome 14 involving the 14q24-q32 region have been identified as deletion 14q (del 14q) syndrome, but were rarely reported. The patients with del 14q syndrome are observed a peculiar facial appearance and neurological defects, but the molecular mechanisms were not clear. Here we generated a human iPSC line from the patient’s amniotic fluid cells with 24 Mb deletion in 14q24.3q32.31 which will serve as useful tools for studying the mechanism of del 14q syndrome and the genes involved, which will provide useful basic theory of prenatal diagnosis.
    Keywords Biology (General) ; QH301-705.5
    Language English
    Publishing date 2021-05-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Generation of induced pluripotent stem cell GZHMCi005-A from amniotic fluid-derived cells with duplication of chromosome 8p.

    Yi, Cheng / Dingya, Cao / Nengqing, Liu / Hongmei, Guan / Yi, Liang / Huimin, Zhang / Jiajia, Xian / Bing, Song / Xiaofang, Sun

    Stem cell research

    2021  Volume 52, Page(s) 102226

    Abstract: Cases in which the duplication of chromosome 8p (dup 8p) is observed are characterized by facial dysmorphism, agenesis/hypoplasia of the corpus callosum, heart defects and severe mental retardation. The frequency of dup 8p cases is higher compared to ... ...

    Abstract Cases in which the duplication of chromosome 8p (dup 8p) is observed are characterized by facial dysmorphism, agenesis/hypoplasia of the corpus callosum, heart defects and severe mental retardation. The frequency of dup 8p cases is higher compared to other chromosomes because of the Non-allelic homologous recombination (NAHR) between two segmental duplication regions (SDs) containing olfactory receptor gene clusters, REPD (repeat-distal) and REPP (repeat-proximal), located in chromosome 8p23.1. Here we generated a human iPSC line from a patient's amniotic fluid cells with a 18 Mb duplication in 8p23.3p22, which will serve as useful tools for studying dup 8p syndrome.
    MeSH term(s) Amniotic Fluid ; Chromosomes ; Chromosomes, Human, Pair 8/genetics ; Humans ; In Situ Hybridization, Fluorescence ; Induced Pluripotent Stem Cells ; Intellectual Disability/genetics
    Language English
    Publishing date 2021-02-05
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1876-7753
    ISSN (online) 1876-7753
    DOI 10.1016/j.scr.2021.102226
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Generation of induced pluripotent stem cell GZHMCi002-A from peripheral blood mononuclear cells with APOB mutation.

    Bing, Song / Nengqing, Liu / Yi, Cheng / Dian, Lu / Diyu, Chen / Yingjun, Xie / Lina, He / Yinghong, Yang / Hongmei, Guan / Xiaofang, Sun

    Stem cell research

    2020  Volume 49, Page(s) 102054

    Abstract: Apolipoprotein (apo) B is a large, amphipathic glycoprotein which plays an important role in human lipoprotein metabolism. The 43-kb APOB gene located on the short arm of human chromosome 2 and consisted of 29 exons, mutations in the APOB gene can give ... ...

    Abstract Apolipoprotein (apo) B is a large, amphipathic glycoprotein which plays an important role in human lipoprotein metabolism. The 43-kb APOB gene located on the short arm of human chromosome 2 and consisted of 29 exons, mutations in the APOB gene can give rise to either hypo- or hypercholesterolemia. We used peripheral blood mononuclear cells (PBMCs) from a volunteer carrying the APOB mutation (c.10579C>T, p.Arg3527Trp) located in exon 9 to establish induced pluripotent stem cells (iPSC), which will be an effective means to reveal the key biologically relevant metabolic mechanisms, a powerful tool for medicine selection and related research.
    MeSH term(s) Apolipoproteins B/genetics ; Exons/genetics ; Humans ; Induced Pluripotent Stem Cells ; Leukocytes, Mononuclear ; Mutation/genetics
    Chemical Substances Apolipoproteins B
    Language English
    Publishing date 2020-10-16
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1876-7753
    ISSN (online) 1876-7753
    DOI 10.1016/j.scr.2020.102054
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

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    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

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