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Article ; Online: Flexible Actuators Based on Conductive Polymer Ionogels and Their Electromechanical Modeling

Jiawei Xu / Hongwei Hu / Shengtao Zhang / Guanggui Cheng / Jianning Ding

Polymers, Vol 15, Iss 23, p

2023 Volume 4482

Abstract: High-performance flexible actuators, integral components of soft robotics, hold promise for advancing applications in safe human–robot interactions, healthcare, and various other fields. Notable among these actuators are flexible electrochemical systems, ...

Abstract	High-performance flexible actuators, integral components of soft robotics, hold promise for advancing applications in safe human–robot interactions, healthcare, and various other fields. Notable among these actuators are flexible electrochemical systems, recognized for their merits in low-voltage manipulation, rapid response speed, and cost-effectiveness. However, the optimization of output strain, response speed, and stability presents a significant challenge in this domain. Despite the application of diverse electrochemically active materials to enhance actuation performance, a critical need persists for corresponding electrical-mechanical models to comprehensively grasp actuation mechanisms. In this study, we introduce a novel electrochemical actuator that utilizes conductive polymer ionogel as active electrodes. This ionogel exhibits exceptional properties, including high conductivity, flexibility, and electrochemical activity. Our electrochemical actuators exhibit noteworthy bending strain capabilities and rapid response rates, achieving frequencies up to 10 Hz at a modest voltage of 1 V. An analytical model integrating ion migration and dynamic processes has been established to elucidate actuator behavior. Simulation results highlight that electrodes characterized by low resistance and high capacitance are optimal for simultaneous enhancement of bending strain and blocking force. However, the augmentation of Young’s modulus, while increasing blocking force, compromises bending strain. Furthermore, a larger aspect ratio proves beneficial for unidirectional stress output, leading to increased bending strain, while actuator blocking force diminishes with greater length. These findings underscore the intricate interplay between material properties and dimensions in optimizing the performance of flexible electrochemical actuators. This work provides important practical and theoretical guidance for the manufacture of high-performance flexible actuators and the search for new smart materials.
Keywords	flexible actuator ; electromechanical model ; conductive polymer ; drive travel ; load capacity ; Organic chemistry ; QD241-441
Subject code	621
Language	English
Publishing date	2023-11-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Study on the Measurement and Influencing Factors of Care Service Demand of Disabled Elderly in Urban and Rural China

Haixia Jiang / Suhua Xiao / Hongwei Hu / Haotian He

International Journal of Environmental Research and Public Health, Vol 19, Iss 11112, p

2022 Volume 11112

Abstract: Caregiving services are currently the weakest part of China’s social security system for the elderly. It is well needed to investigate the fac-tors affecting the unmet care needs of the elderly with disabilities. Based on the Behavioral Model of Health ... ...

Abstract	Caregiving services are currently the weakest part of China’s social security system for the elderly. It is well needed to investigate the fac-tors affecting the unmet care needs of the elderly with disabilities. Based on the Behavioral Model of Health Services Use (BMHSU), this paper explores the needs and influencing factors of care services for the disabled elderly in urban and rural areas using data from the 2018 Project of Social Policy Support System for Disadvantaged Families in China. The demand for care services of the disabled elderly in central and western areas is significantly higher than that in eastern, along with that in rural areas significantly higher than that in urban areas. The demands for care services of the disabled elderly in urban and rural areas are significantly affected by tendency factors, resource factors, and need factors. Urban and rural attributes, worried pension and LCI are the common influencing factors for the care service demand of the disabled elderly from economically disadvantaged families and ordinary families. The demands for care services of the disabled elderly were associated with tendencies, resources, and needs, increased chronic disease prevention and mental health services benefit caregivers.
Keywords	population aging ; urban and rural disability elderly ; disadvantaged families ; care service demand ; MIMIC structural equation model ; Medicine ; R
Subject code	360
Language	English
Publishing date	2022-09-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Multivisual Animation Character 3D Model Design Method Based on VR Technology

Leiming Li / Wenyao Zhu / Hongwei Hu

Complexity, Vol

2021 Volume 2021

Abstract: For VR systems, one of its core parts is to present people with a real and immersive 3D simulation environment. This paper uses real-time computer graphics technology, three-dimensional modeling technology, and binocular stereo vision technology to study ...

Abstract	For VR systems, one of its core parts is to present people with a real and immersive 3D simulation environment. This paper uses real-time computer graphics technology, three-dimensional modeling technology, and binocular stereo vision technology to study the multivisual animation character objects in virtual reality technology; designs a binocular stereo vision animation system; designs and produces a three-dimensional model; and develops a virtual multivisual animation scene application. The main research content and work performed in the text include the research of the basic graphics rendering pipeline process and the analysis and research of each stage of the rendering pipeline. It mainly analyzes the 3D graphics algorithm used in the three-dimensional geometric transformation of computer graphics and studies the basic texture technology, basic lighting model, and other image output processes used in the fragment processing stage. Combined with the development needs of the subject, the principles of 3D animation rendering production software and 3D graphics modeling are studied, and the solid 3D model displayed in the virtual reality scene is designed and produced. This article also reflects the application of virtual reality in multivisual animation character design from the side, so it has realistic value and application prospects.
Keywords	Electronic computers. Computer science ; QA75.5-76.95
Subject code	629
Language	English
Publishing date	2021-01-01T00:00:00Z
Publisher	Hindawi-Wiley
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Rural women empowerment through social protection programs

Zonaira Naseer / Hongwei Hu / Muhammad Yaseen / Muhammad Tariq

Journal of the Saudi Society of Agricultural Sciences, Vol 20, Iss 2, Pp 67-

A case of Benazir income support programme in Punjab, Pakistan

2021 Volume 74

Abstract: Benazir Income Support Program (BISP) is one of social protection programs providing unconditional financial assistance to poor women. The present study was conducted to explore the role of BISP in empowering women. This quantitative research was ... ...

Abstract	Benazir Income Support Program (BISP) is one of social protection programs providing unconditional financial assistance to poor women. The present study was conducted to explore the role of BISP in empowering women. This quantitative research was conducted in two districts of Punjab randomly selected out of 36 using face-to-face interviews with a sample size of 160 women beneficiaries of BISP. Research findings show that the majority of beneficiaries (78.8%) were married, with rural background (88%). A huge number (80%) of beneficiaries were illiterate. Similarly, overwhelming majority (81.9%) of respondents has labor as source of income. Most of the respondents were strongly agree (65%) and agree (95%) that the assistance should be more than Rs.5000/month or Rs.10000/month. Similarly, 69.4% and 71.3% of respondents agreed that female adults should take household decision and children should attend school regardless of gender. The government should provide appropriate assistance allowance for needy families especially for the empowerment of women. Moreover, the government should also launch massive programs to maximize girls' education with motive to empower women.
Keywords	BISP ; Poverty reduction ; Social protection ; Social security ; Women empowerment ; Agriculture (General) ; S1-972
Subject code	360
Language	English
Publishing date	2021-02-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Adverse Childhood Experiences and Psychological Well-Being in Chinese College Students

Chien-Chung Huang / Yuanfa Tan / Shannon P. Cheung / Hongwei Hu

International Journal of Environmental Research and Public Health, Vol 18, Iss 1636, p

Mediation Effect of Mindfulness

2021 Volume 1636

Abstract: Literature on the antecedents of psychological well-being (PWB) has found that adverse childhood experiences (ACEs) and mindfulness are associated with PWB; less is known, however, about the role of mindfulness, a type of emotional and self-regulation, ... ...

Abstract	Literature on the antecedents of psychological well-being (PWB) has found that adverse childhood experiences (ACEs) and mindfulness are associated with PWB; less is known, however, about the role of mindfulness, a type of emotional and self-regulation, in the pathway between ACEs and PWB. This study used data from 1871 college students across China to examine the relation between ACEs and PWB, and whether the relation was mediated by mindfulness. The findings from structural equation modelling indicate a statistically significant negative association between ACEs and PWB, while mindfulness was strongly and positively associated with PWB. The effect of ACEs on PWB was reduced once mindfulness was controlled for in the analysis. This provides evidence that mindfulness was able to partially mediate the effects of negative life experiences on psychological well-being. This calls for mindfulness interventions targeted toward students with a history of ACEs to buffer the effects of ACEs on PWB.
Keywords	psychological well-being ; mindfulness ; adverse childhood experiences ; students ; China ; college ; Medicine ; R
Subject code	150
Language	English
Publishing date	2021-02-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Overcoming resistance to immunotherapy by targeting GPR84 in myeloid-derived suppressor cells

Guohui Qin / Shasha Liu / Jinyan Liu / Hongwei Hu / Li Yang / Qitai Zhao / Congcong Li / Bin Zhang / Yi Zhang

Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-

2023 Volume 15

Abstract: Abstract Myeloid-derived suppressor cells (MDSCs) were found to gradually accumulate in the orthotopic esophageal cancer mouse model during tumor progression. Although the roles of MDSCs in promoting tumor growth and inhibiting immune response have been ... ...

Abstract	Abstract Myeloid-derived suppressor cells (MDSCs) were found to gradually accumulate in the orthotopic esophageal cancer mouse model during tumor progression. Although the roles of MDSCs in promoting tumor growth and inhibiting immune response have been extensively explored, currently, there are still no effective means for targeting MDSCs clinically. The deficiency of specific markers of MDSCs was responsible for the limited strategy to eliminating in clinic. This study identified that GPR84 was exclusively overexpressed on MDSCs. It was further found that GPR84 was prominently expressed on MDSCs in clinical samples and tumor mouse models, which drives the immunosuppression on CD8+T cells by inhibiting PD-L1 degradation in lysosomes. Furthermore, G-CSF and GM-CSF were found to induce GPR84 expression through the STAT3/C/EBPβ signaling pathway. In addition, GPR84+MDSCs and PD-L1+MDSCs were highly accumulated in anti-PD-1 therapy-resistant patients with esophageal cancer, and high GPR84 signature risk was verified as a negative factor for the overall survival of patients with anti-PD-1 treatment. Finally, GPR84 antagonism combined with an anti-PD-1 antibody enhanced the antitumor responses. Therefore, targeting GPR84 enhanced anti-PD-1 efficacy in esophageal cancer and other malignant tumors. This combination therapy has the potential for tumor therapy in clinics.
Keywords	Medicine ; R ; Biology (General) ; QH301-705.5
Subject code	610
Language	English
Publishing date	2023-04-01T00:00:00Z
Publisher	Nature Publishing Group
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Machine learning predictors of risk of death within 7 days in patients with non-traumatic subarachnoid hemorrhage in the intensive care unit

Longyuan Gu / Hongwei Hu / Shinan Wu / Fengda Li / Zeyi Li / Yaodong Xiao / Chuanqing Li / Hui Zhang / Qiang Wang / Wenle Li / Yuechao Fan

Heliyon, Vol 10, Iss 1, Pp e23943- (2024)

A multicenter retrospective study

1481

Abstract: Non-traumatic subarachnoid hemorrhage (SAH) is a critical neurosurgical emergency with a high mortality rate, imposing a significant burden on both society and families. Accurate prediction of the risk of death within 7 days in SAH patients can provide ... ...

Abstract	Non-traumatic subarachnoid hemorrhage (SAH) is a critical neurosurgical emergency with a high mortality rate, imposing a significant burden on both society and families. Accurate prediction of the risk of death within 7 days in SAH patients can provide valuable information for clinicians, enabling them to make better-informed medical decisions. In this study, we developed six machine learning models using the MIMIC III database and data collected at our institution. These models include Logistic Regression (LR), AdaBoosting (AB), Multilayer Perceptron (MLP), Bagging (BAG), Gradient Boosting Machines (GBM), and Extreme Gradient Boosting (XGB). The primary objective was to identify predictors of death within 7 days in SAH patients admitted to intensive care units. We employed univariate and multivariate logistic regression as well as Pearson correlation analysis to screen the clinical variables of the patients. The initially screened variables were then incorporated into the machine learning models, and the performance of these models was evaluated. Furthermore, we compared the performance differences among the six models and found that the MLP model exhibited the highest performance with an AUC of 0.913. In this study, we conducted risk factor analysis using Shapley values to identify the factors associated with death within 7 days in patients with SAH. The risk factors we identified include Gcsmotor, bicarbonate, wbc, spo2, heartrate, age, nely, glucose, aniongap, GCS, rbc, sysbp, sodium, and gcseys. To provide clinicians with a useful tool for assessing the risk of death within 7 days in SAH patients, we developed a web calculator based on the MLP machine learning model.
Keywords	Non-traumatic subarachnoid hemorrhage ; Predictors ; Machine learning ; Prediction model ; Web calculator ; Science (General) ; Q1-390 ; Social sciences (General) ; H1-99
Subject code	310
Language	English
Publishing date	2024-01-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: A comparative study of unintentional injuries among schooling left-behind, migrant and residential children in China

Hongwei Hu / Jiamin Gao / Haochen Jiang / Pingnan Xing

International Journal for Equity in Health, Vol 17, Iss 1, Pp 1-

2018 Volume 10

Abstract: Abstract Background Children who suffer from parental migration have been manifested to exhibit physical and mental impairments at higher rates. This current study aims to explore unintentional injury disparity among schooling left-behind children, ... ...

Abstract	Abstract Background Children who suffer from parental migration have been manifested to exhibit physical and mental impairments at higher rates. This current study aims to explore unintentional injury disparity among schooling left-behind children, migrant children and residential children in China, and to examine the risk factors of unintentional injury among the three types of children based on a multi-level system framework. This study will fill the gaps of this topic for China and contribute to the world literature in the context of countries with frequent population migration. Methods Data for 4479 children aged 6–16 of a representative population sample were obtained from a survey conducted in China in 2017. Child’s unintentional injury in this survey was measured based on the definition and classification of ICD-10. Descriptive analysis, multivariable logistic regression and zero-inflated negative binomial regression were employed in this study. Results Left-behind children showed higher prevalence of total unintentional injury than migrant and residential children, as well as in 14 specific unintentional injuries. There was a statistical difference between left-behind and residential children’s unintentional injuries, but no significant difference was found between migrant and residential children. Results also indicated that both individual and environmental factors constructed as a multi-level system were associated with children’s unintentional injuries. Conclusions Family migration may have contributed to the increased unintentional injury risks among children. Left-behind children were more vulnerable to suffer from unintentional injuries than migrant and residential children, and specific attentions should be paid to unique group of children, especially the left-behind children. Given the importance and serious consequences of children’s unintentional injuries, the findings may provide implications for necessary intervention.
Keywords	Unintentional injury ; Left-behind children ; Migrant children ; Family migration ; Risk factor ; Public aspects of medicine ; RA1-1270
Subject code	360 ; 331
Language	English
Publishing date	2018-04-01T00:00:00Z
Publisher	BMC
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: The comparison of healthcare utilization inequity between URRBMI and NCMS in rural China

Zengwen Wang / Yucheng Chen / Tianyi Pan / Xiaodi Liu / Hongwei Hu

International Journal for Equity in Health, Vol 18, Iss 1, Pp 1-

2019 Volume 12

Abstract: Abstract Background The inequity of healthcare utilization in rural China is serious, and the urban-rural segmentation of the medical insurance system intensifies this problem. To guarantee that the rural population enjoys the same medical insurance ... ...

Abstract	Abstract Background The inequity of healthcare utilization in rural China is serious, and the urban-rural segmentation of the medical insurance system intensifies this problem. To guarantee that the rural population enjoys the same medical insurance benefits, China began to establish Urban and Rural Resident Basic Medical Insurance (URRBMI) nationwide in 2016. Against this backdrop, this paper aims to compare the healthcare utilization inequity between URRBMI and New Cooperative Medical Schemes (NCMS) and to analyze whether the inequity is reduced under URRBMI in rural China. Methods Using the data from a national representative survey, the China Health and Retirement Longitudinal Study (CHARLS), which was conducted in 2015, a binary logistic regression model was applied to analyze the influence of income on healthcare utilization, and the decomposition of the concentration index was adopted to compare the Horizontal inequity index (HI index) of healthcare utilization among the individuals insured by URRBMI and NCMS. Results There is no statistically significant difference in healthcare utilization between URRBMI and NCMS, but in outpatient utilization, there are significant differences among different income groups in NCMS; high-income groups utilize more outpatient care. The Horizontal inequity indexes (HI indexes) in outpatient utilization for individuals insured by URRBMI and NCMS are 0.024 and 0.012, respectively, indicating a pro-rich inequity. Meanwhile, the HI indexes in inpatient utilization under the two groups are − 0.043 and − 0.028, respectively, meaning a pro-poor inequity. For both the outpatient and inpatient care, the inequity degree of URRBMI is larger than that of NCMS. Conclusions This paper shows that inequity still exists in rural areas after the integration of urban-rural medical insurance schemes, and there is still a certain gap between the actual and the expected goal of URRBMI. Specifically, compared to NCMS, the pro-rich inequity in outpatient care and the pro-poor inequity in ...
Keywords	The integration of urban-rural medical insurance ; Healthcare utilization ; Inequity ; Horizontal inequity index ; Public aspects of medicine ; RA1-1270
Subject code	650
Language	English
Publishing date	2019-06-01T00:00:00Z
Publisher	BMC
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Gut Microbiota Dysbiosis Associated with Bile Acid Metabolism in Neonatal Cholestasis Disease

Meng Li / Sixiang Liu / Mingying Wang / Hongwei Hu / Jianwen Yin / Chuanfa Liu / Yongkun Huang

Scientific Reports, Vol 10, Iss 1, Pp 1-

2020 Volume 10

Abstract: Abstract Neonatal cholestasis disease (NCD) is a complex and easily mis-diagnosed condition. We analyzed microbiota community structure in feces and measured short-chain fatty acids, bile acids (BAs) and liver function of 12 healthy, 13 NCD, and 13 ... ...

Abstract	Abstract Neonatal cholestasis disease (NCD) is a complex and easily mis-diagnosed condition. We analyzed microbiota community structure in feces and measured short-chain fatty acids, bile acids (BAs) and liver function of 12 healthy, 13 NCD, and 13 treated infants after diagnosis. Based on 16S rRNA gene amplicon sequencing and gas-chromatographic-mass-spectrometric analysis of secondary BAs, we identified microbial genera and metabolites that associate with abnormal bile secretion. Streptococcus gallolyticus and Parabacteroides distasonis, and Lactobacillus gasseri had higher relative abundance in healthy and NCD infants respectively. Compared to NCD patients, healthy infants had higher LCA, CDCA and GCDCA fecal concentrations. The three microbial species and three secondary bile acids were selected as potential non-invasive combined biomarkers to diagnose NCD. We propose that microbiota-metabolite combined biomarkers could be used for diagnosis of NCD, and this may contribute to improved early clinical diagnosis of NCD in the future.
Keywords	Medicine ; R ; Science ; Q
Subject code	610
Language	English
Publishing date	2020-05-01T00:00:00Z
Publisher	Nature Publishing Group
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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